Thomas J Whitford

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi request reprint Brain maturation in adolescence: concurrent changes in neuroanatomy and neurophysiology
    Thomas J Whitford
    Brain Dynamics Centre, Westmead Millennium Institute, University of Sydney, Westmead Hospital, New South Wales, Australia
    Hum Brain Mapp 28:228-37. 2007
  2. doi request reprint Delusions and dorso-medial frontal cortex volume in first-episode schizophrenia: a voxel-based morphometry study
    Thomas J Whitford
    The Brain Dynamics Centre, Westmead Millennium Institute and University of Sydney, Westmead, NSW, 2145, Australia
    Psychiatry Res 172:175-9. 2009
  3. ncbi request reprint Volumetric white matter abnormalities in first-episode schizophrenia: a longitudinal, tensor-based morphometry study
    Thomas J Whitford
    Brain Dynamics Centre, Acacia House, Westmead Hospital, Westmead, NSW, 2145, Australia
    Am J Psychiatry 164:1082-9. 2007
  4. ncbi request reprint Progressive grey matter atrophy over the first 2-3 years of illness in first-episode schizophrenia: a tensor-based morphometry study
    Thomas J Whitford
    The Brain Dynamics Centre, Westmead Millennium Institute and University of Sydney, Acacia House, Westmead Hospital, NSW 2145, Australia
    Neuroimage 32:511-9. 2006
  5. ncbi request reprint Investigating the neuropsychological and neuroanatomical changes that occur over the first 2-3 years of illness in patients with first-episode schizophrenia
    Lisa Zipparo
    Department of Psychology, Macquarie University, North Ryde, NSW, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 32:531-8. 2008
  6. ncbi request reprint Longitudinal changes in neuroanatomy and neural activity in early schizophrenia
    Thomas J Whitford
    The Brain Dynamics Centre, Westmead Millennium Institute and University of Sydney, and Acacia House, Westmead Hospital, New South Wales, Australia
    Neuroreport 18:435-9. 2007
  7. doi request reprint Duration of posttraumatic stress disorder predicts hippocampal grey matter loss
    Kim Felmingham
    Brain Dynamics Centre, Westmead Millennium Institute, Westmead Hospital, Australia
    Neuroreport 20:1402-6. 2009
  8. pmc Emotion-elicited gamma synchrony in patients with first-episode schizophrenia: a neural correlate of social cognition outcomes
    Leanne M Williams
    Brain Dynamics Centre, Westmead Millennium Institute and Western Clinical School, University of Sydney, Westmead Hospital, Westmead NSW, Australia
    J Psychiatry Neurosci 34:303-13. 2009
  9. pmc Neural synchrony in patients with a first episode of schizophrenia: tracking relations with grey matter and symptom profile
    Leanne M Williams
    Brain Dynamics Centre, Westmead Millennium Institute and Western Clinical School, University of Sydney, Westmead, Sydney, Australia
    J Psychiatry Neurosci 34:21-9. 2009
  10. ncbi request reprint Diagnosis-related regional gray matter loss over two years in first episode schizophrenia and bipolar disorder
    Tom F D Farrow
    Brain Dynamics Centre, Westmead Hospital, Westmead SCANLab, Department of Academic Clinical Psychiatry, University of Sheffield, United Kingdom
    Biol Psychiatry 58:713-23. 2005

Detail Information

Publications17

  1. ncbi request reprint Brain maturation in adolescence: concurrent changes in neuroanatomy and neurophysiology
    Thomas J Whitford
    Brain Dynamics Centre, Westmead Millennium Institute, University of Sydney, Westmead Hospital, New South Wales, Australia
    Hum Brain Mapp 28:228-37. 2007
    ..We suggest that the reduction in gray matter primarily reflects a reduction of neuropil, and that the corresponding elimination of active synapses is responsible for the observed reduction in EEG power...
  2. doi request reprint Delusions and dorso-medial frontal cortex volume in first-episode schizophrenia: a voxel-based morphometry study
    Thomas J Whitford
    The Brain Dynamics Centre, Westmead Millennium Institute and University of Sydney, Westmead, NSW, 2145, Australia
    Psychiatry Res 172:175-9. 2009
    ....
  3. ncbi request reprint Volumetric white matter abnormalities in first-episode schizophrenia: a longitudinal, tensor-based morphometry study
    Thomas J Whitford
    Brain Dynamics Centre, Acacia House, Westmead Hospital, Westmead, NSW, 2145, Australia
    Am J Psychiatry 164:1082-9. 2007
    ....
  4. ncbi request reprint Progressive grey matter atrophy over the first 2-3 years of illness in first-episode schizophrenia: a tensor-based morphometry study
    Thomas J Whitford
    The Brain Dynamics Centre, Westmead Millennium Institute and University of Sydney, Acacia House, Westmead Hospital, NSW 2145, Australia
    Neuroimage 32:511-9. 2006
    ..We argue that the progressive GM atrophy we have found to be associated with the onset of schizophrenia arises from a dysfunction in the dramatic period of healthy brain development typically associated with adolescence...
  5. ncbi request reprint Investigating the neuropsychological and neuroanatomical changes that occur over the first 2-3 years of illness in patients with first-episode schizophrenia
    Lisa Zipparo
    Department of Psychology, Macquarie University, North Ryde, NSW, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 32:531-8. 2008
    ..This study explored the concurrent courses of the neuroanatomical and neuropsychological changes that occurred over the first 2-3 years of illness in patients with first-episode schizophrenia (FES)...
  6. ncbi request reprint Longitudinal changes in neuroanatomy and neural activity in early schizophrenia
    Thomas J Whitford
    The Brain Dynamics Centre, Westmead Millennium Institute and University of Sydney, and Acacia House, Westmead Hospital, New South Wales, Australia
    Neuroreport 18:435-9. 2007
    ..These results suggest that first-episode schizophrenia may be associated with abnormally elevated levels of neural synchrony...
  7. doi request reprint Duration of posttraumatic stress disorder predicts hippocampal grey matter loss
    Kim Felmingham
    Brain Dynamics Centre, Westmead Millennium Institute, Westmead Hospital, Australia
    Neuroreport 20:1402-6. 2009
    ..This pattern suggests that prolonged PTSD may have cumulative adverse effects on hippocampal volume, highlighting the potential role of genetic-environmental interactions...
  8. pmc Emotion-elicited gamma synchrony in patients with first-episode schizophrenia: a neural correlate of social cognition outcomes
    Leanne M Williams
    Brain Dynamics Centre, Westmead Millennium Institute and Western Clinical School, University of Sydney, Westmead Hospital, Westmead NSW, Australia
    J Psychiatry Neurosci 34:303-13. 2009
    ....
  9. pmc Neural synchrony in patients with a first episode of schizophrenia: tracking relations with grey matter and symptom profile
    Leanne M Williams
    Brain Dynamics Centre, Westmead Millennium Institute and Western Clinical School, University of Sydney, Westmead, Sydney, Australia
    J Psychiatry Neurosci 34:21-9. 2009
    ..We examined relations between 40 Hz Gamma band synchrony and grey matter in patients with schizophrenia at first episode and after 2.5 years...
  10. ncbi request reprint Diagnosis-related regional gray matter loss over two years in first episode schizophrenia and bipolar disorder
    Tom F D Farrow
    Brain Dynamics Centre, Westmead Hospital, Westmead SCANLab, Department of Academic Clinical Psychiatry, University of Sheffield, United Kingdom
    Biol Psychiatry 58:713-23. 2005
    ..We predicted that FEP subjects would show longitudinal reductions in fronto-temporal gray- and white-matter volumes compared with controls. Furthermore, we expected groups to be differentiated by diagnosis-related reductions...
  11. ncbi request reprint Grey matter deficits and symptom profile in first episode schizophrenia
    Thomas J Whitford
    The Brain Dynamics Centre, Acacia House, Westmead Hospital and Western Clinical School, University of Sydney, Westmead Hospital, Westmead, NSW 2145, Australia
    Psychiatry Res 139:229-38. 2005
    ..The results also suggest a possible structural underpinning for the abnormal brain activity typically associated with symptoms of Reality Distortion...
  12. ncbi request reprint General and social cognition in first episode schizophrenia: identification of separable factors and prediction of functional outcome using the IntegNeuro test battery
    Leanne M Williams
    The Brain Dynamics Centre, Westmead Millennium Institute and Western Clinical School, University of Sydney, Westmead Hospital, NSW, 2145, Australia
    Schizophr Res 99:182-91. 2008
    ..We determined the presence of separable factors of general and social cognition, their equivalence to the consensus domains identified by the NIMH MATRICS project, and their effectiveness in predicting real world functional outcomes...
  13. ncbi request reprint Functional disconnections in the direct and indirect amygdala pathways for fear processing in schizophrenia
    Pritha Das
    Neuroscience Institute of Schizophrenia and Allied Disorders, Darlinghurst, NSW 2010, Australia
    Schizophr Res 90:284-94. 2007
    ..In this study we tested the hypothesis that schizophrenia is characterized by abnormal functional connectivity in the amygdala network underlying fear perception...
  14. ncbi request reprint Neural synchrony and gray matter variation in human males and females: integration of 40 Hz gamma synchrony and MRI measures
    Leanne M Williams
    The Brain Dynamics Center, University of Sydney and Westmead Hospital, NSW 2145, Australia
    J Integr Neurosci 4:77-93. 2005
    ..Sex differences in the profile of cortical synchronization may reflect distinct aspects of evolutionary advantage...
  15. pmc Rostral anterior cingulate volume predicts treatment response to cognitive-behavioural therapy for posttraumatic stress disorder
    Richard A Bryant
    Brain Dynamics Centre, Westmead Hospital, Sydney, Australia
    J Psychiatry Neurosci 33:142-6. 2008
    ..To index the extent to which treatment response in posttraumatic stress disorder (PTSD) is predicted by rostral anterior cingulate cortex (rACC) volume...
  16. ncbi request reprint The relationship between frontal gray matter volume and cognition varies across the healthy adult lifespan
    Molly E Zimmerman
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island, USA
    Am J Geriatr Psychiatry 14:823-33. 2006
    ..The goal of the current study is to examine the relationship between age-related changes in regional gray matter volumes and cognitive function in a large, cross-sectional sample of healthy adults across the lifespan...
  17. ncbi request reprint Diffusion tensor imaging of the corpus callosum: a cross-sectional study across the lifespan
    Nicole C R McLaughlin
    Brown Medical School, Department of Psychiatry and Human Behavior, Providence, RI 02912, USA
    Int J Dev Neurosci 25:215-21. 2007
    ..These results define the microstructural development of the white matter across the lifespan. Future studies are required to examine the neurobehavioral correlates of these neuroimaging indices...