J R Walton

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi A bright field/fluorescent stain for aluminum: its specificity, validation, and staining characteristics
    J R Walton
    Australian Institute for Biomedical Research, Marrickville Sydney NSW, Australia
    Biotech Histochem 79:169-76. 2004
  2. doi Brain lesions comprised of aluminum-rich cells that lack microtubules may be associated with the cognitive deficit of Alzheimer's disease
    J R Walton
    Australian Institute for Biomedical Research, Sydney, NSW 2204, Australia
    Neurotoxicology 30:1059-69. 2009
  3. doi Evidence for participation of aluminum in neurofibrillary tangle formation and growth in Alzheimer's disease
    J R Walton
    St George Hospital Clinical School, University of New South Wales Faculty of Medicine, Sydney, NSW, Australia
    J Alzheimers Dis 22:65-72. 2010
  4. ncbi Aluminum in hippocampal neurons from humans with Alzheimer's disease
    J R Walton
    Australian Institute for Biomedical Research, Sydney, NSW 2204, Australia
    Neurotoxicology 27:385-94. 2006
  5. ncbi A longitudinal study of rats chronically exposed to aluminum at human dietary levels
    J R Walton
    Australian Institute for Biomedical Research, Sydney, NSW 2204, Australia
    Neurosci Lett 412:29-33. 2007
  6. pmc A two-year clinical outcomes study of 400 patients, comparing open surgery and arthroscopy for rotator cuff repair
    J R Walton
    Orthopaedic Research Institute ORI, University of New South Wales, St George Hospital Campus, Sydney, New South Wales 2217, Australia
    Bone Joint Res 1:210-7. 2012
  7. ncbi Aluminum involvement in the progression of Alzheimer's disease
    J R Walton
    Faculty of Medicine, University of New South Wales, St George Hospital Campus, Sydney NSW, Australia
    J Alzheimers Dis 35:7-43. 2013
  8. doi APP expression, distribution and accumulation are altered by aluminum in a rodent model for Alzheimer's disease
    J R Walton
    Australian Institute for Biomedical Research, Sydney NSW, Australia
    J Inorg Biochem 103:1548-54. 2009
  9. doi Functional impairment in aged rats chronically exposed to human range dietary aluminum equivalents
    J R Walton
    Australian Institute for Biomedical Research, NSW, Australia
    Neurotoxicology 30:182-93. 2009
  10. ncbi A sensitive stain for aluminum in undecalcified cancellous bone
    J R Walton
    Department of Orthopaedic Surgery, University of New South Wales, St George Hospital Campus, Sydney NSW 2217, Australia
    J Inorg Biochem 101:1285-90. 2007

Collaborators

Detail Information

Publications15

  1. ncbi A bright field/fluorescent stain for aluminum: its specificity, validation, and staining characteristics
    J R Walton
    Australian Institute for Biomedical Research, Marrickville Sydney NSW, Australia
    Biotech Histochem 79:169-76. 2004
    ....
  2. doi Brain lesions comprised of aluminum-rich cells that lack microtubules may be associated with the cognitive deficit of Alzheimer's disease
    J R Walton
    Australian Institute for Biomedical Research, Sydney, NSW 2204, Australia
    Neurotoxicology 30:1059-69. 2009
    ..These lesions expand over time, disrupting afferent and efferent hippocampal circuitry with the development of clinically overt dementia...
  3. doi Evidence for participation of aluminum in neurofibrillary tangle formation and growth in Alzheimer's disease
    J R Walton
    St George Hospital Clinical School, University of New South Wales Faculty of Medicine, Sydney, NSW, Australia
    J Alzheimers Dis 22:65-72. 2010
    ..The photographic evidence presented combines with existing evidence to support a role for aluminum in the formation and growth of NFTs in neurons of humans with Alzheimer's disease...
  4. ncbi Aluminum in hippocampal neurons from humans with Alzheimer's disease
    J R Walton
    Australian Institute for Biomedical Research, Sydney, NSW 2204, Australia
    Neurotoxicology 27:385-94. 2006
    ....
  5. ncbi A longitudinal study of rats chronically exposed to aluminum at human dietary levels
    J R Walton
    Australian Institute for Biomedical Research, Sydney, NSW 2204, Australia
    Neurosci Lett 412:29-33. 2007
    ..In view of evidenced linkages of aluminum with beta-amyloid plaque and neurofibrillary tangle formation in humans with Alzheimer's disease, the findings suggest this protocol is worth testing in larger groups of animals...
  6. pmc A two-year clinical outcomes study of 400 patients, comparing open surgery and arthroscopy for rotator cuff repair
    J R Walton
    Orthopaedic Research Institute ORI, University of New South Wales, St George Hospital Campus, Sydney, New South Wales 2217, Australia
    Bone Joint Res 1:210-7. 2012
    ....
  7. ncbi Aluminum involvement in the progression of Alzheimer's disease
    J R Walton
    Faculty of Medicine, University of New South Wales, St George Hospital Campus, Sydney NSW, Australia
    J Alzheimers Dis 35:7-43. 2013
    ..This review describes evidence for aluminum involvement in AD neuropathology and the clinical progression of sporadic AD...
  8. doi APP expression, distribution and accumulation are altered by aluminum in a rodent model for Alzheimer's disease
    J R Walton
    Australian Institute for Biomedical Research, Sydney NSW, Australia
    J Inorg Biochem 103:1548-54. 2009
    ..Aluminum may thus launch the cascade that results in the formation of amyloid plaques in human brain...
  9. doi Functional impairment in aged rats chronically exposed to human range dietary aluminum equivalents
    J R Walton
    Australian Institute for Biomedical Research, NSW, Australia
    Neurotoxicology 30:182-93. 2009
    ..Hence, in this longitudinal study, ingestion of 0.5mg aluminum/(kg bodyweight day) or more, consumed throughout most of adult life led, in old age, to a slowly-progressing condition that impaired cognitive function in susceptible rats...
  10. ncbi A sensitive stain for aluminum in undecalcified cancellous bone
    J R Walton
    Department of Orthopaedic Surgery, University of New South Wales, St George Hospital Campus, Sydney NSW 2217, Australia
    J Inorg Biochem 101:1285-90. 2007
    ..As the ASA and Walton methods are considerably more sensitive for bone aluminum than the Aluminon method, we recommend that either of them should be used in place of the Aluminon method for routine diagnostic purposes...
  11. ncbi An aluminum-based rat model for Alzheimer's disease exhibits oxidative damage, inhibition of PP2A activity, hyperphosphorylated tau, and granulovacuolar degeneration
    J R Walton
    Australian Institute for Biomedical Research, Sydney, NSW, Australia
    J Inorg Biochem 101:1275-84. 2007
    ..As neuronal aluminum can account for early stages of plaque and tangle formation in an animal model for AD, neuronal aluminum could also initiate plaque and tangle formation in humans with AD...
  12. doi Aluminum disruption of calcium homeostasis and signal transduction resembles change that occurs in aging and Alzheimer's disease
    J R Walton
    UNSW Faculty of Medicine, University of New South Wales, St George Hospital Campus, Sydney, NSW, Australia
    J Alzheimers Dis 29:255-73. 2012
    ....
  13. ncbi Reliability of a new shoulder laxometer to assess inferior glenohumeral joint translation
    M L Sein
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Australia
    Br J Sports Med 42:178-82. 2008
    ..This study tested the reliability of the ORI laxometer, a newly developed non-invasive device for testing inferior translation of the humeral head in humans...
  14. ncbi Reliability of five methods for assessing shoulder range of motion
    K Hayes
    Department of Orthopaedic Surgery, St George Hospital, Kogarah, New South Wales 2217
    Aust J Physiother 47:289-94. 2001
    ..53-0.65) and still photography (Inter-rater Rho = 0.62-0.73; Intra-rater Rho = 0.56-0.61). The tests had standard errors of measurement of between 14 and 25 degrees (inter-rater trial) and 11 and 23 degrees (intra-rater trial)...