D Wakefield

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. pmc Are patients with inflammatory eye disease treated with systemic immunosuppressive therapy at increased risk of malignancy?
    William B Yates
    Inflammation Research Unit, School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    J Ophthalmic Inflamm Infect 3:48. 2013
  2. doi request reprint Scleritis: Immunopathogenesis and molecular basis for therapy
    Denis Wakefield
    School of Medical Sciences, UNSW Medicine, University of New South Wales, Sydney, NSW 2052, Australia
    Prog Retin Eye Res 35:44-62. 2013
  3. doi request reprint Treatment of severe inflammatory eye disease in patients of reproductive age and during pregnancy
    Denis Wakefield
    School of Medical Sciences, University of New South Wales, Sydney, Australia
    Ocul Immunol Inflamm 20:277-87. 2012
  4. doi request reprint Controversies in Behçet disease
    Denis Wakefield
    School of Medical Sciences, University of New South Wales, Sydney, Australia
    Ocul Immunol Inflamm 20:6-11. 2012
  5. ncbi request reprint Vernal keratoconjunctivitis
    Denis Wakefield
    School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia
    Med J Aust 185:523. 2006
  6. ncbi request reprint Intravenous pulse methylprednisolone in the treatment of uveitis associated with multiple sclerosis
    D Wakefield
    School of Pathology University of New South Wales, Department of Ophthalmology, St Vincent s Hospital, Sydney, Australia
    Clin Experiment Ophthalmol 28:103-6. 2000
  7. doi request reprint Controversy: ocular sarcoidosis
    Denis Wakefield
    Faculty of Medicine, University of New South Wales, Kensington, Sydney, New South Wales, Australia
    Ocul Immunol Inflamm 18:5-9. 2010
  8. doi request reprint What is new HLA-B27 acute anterior uveitis?
    Denis Wakefield
    School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia
    Ocul Immunol Inflamm 19:139-44. 2011
  9. doi request reprint The role of PAMPs and DAMPs in the pathogenesis of acute and recurrent anterior uveitis
    Denis Wakefield
    Laboratory of Ocular Immunology, Centre for Inflammation and Immunology, Faculty of Medicine University of New South Wales, Sydney, Australia
    Br J Ophthalmol 94:271-4. 2010
  10. ncbi request reprint Role and regulation of CXC-chemokines in acute experimental keratitis
    M L Xue
    Cooperative Research Centre for Eye Research and Technology, Cornea and Contact Lens Research Unit, The University of New South Wales, Sydney, NSW 2052, Australia
    Exp Eye Res 76:221-31. 2003

Detail Information

Publications78

  1. pmc Are patients with inflammatory eye disease treated with systemic immunosuppressive therapy at increased risk of malignancy?
    William B Yates
    Inflammation Research Unit, School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    J Ophthalmic Inflamm Infect 3:48. 2013
    ..Until such evidence is available, we recommend the adoption of preventative strategies to help minimise the risk of malignancy in such patients. ..
  2. doi request reprint Scleritis: Immunopathogenesis and molecular basis for therapy
    Denis Wakefield
    School of Medical Sciences, UNSW Medicine, University of New South Wales, Sydney, NSW 2052, Australia
    Prog Retin Eye Res 35:44-62. 2013
    ....
  3. doi request reprint Treatment of severe inflammatory eye disease in patients of reproductive age and during pregnancy
    Denis Wakefield
    School of Medical Sciences, University of New South Wales, Sydney, Australia
    Ocul Immunol Inflamm 20:277-87. 2012
    ..Most drugs are excluded from use in pregnancy not because of proven teratogenicity but because of the lack of available evidence of their safety for the fetus...
  4. doi request reprint Controversies in Behçet disease
    Denis Wakefield
    School of Medical Sciences, University of New South Wales, Sydney, Australia
    Ocul Immunol Inflamm 20:6-11. 2012
    ..The survey results revealed significant disparities between responders in terms of important concepts regarding the clinical features, diagnosis, and treatment of this important inflammatory eye disease...
  5. ncbi request reprint Vernal keratoconjunctivitis
    Denis Wakefield
    School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia
    Med J Aust 185:523. 2006
  6. ncbi request reprint Intravenous pulse methylprednisolone in the treatment of uveitis associated with multiple sclerosis
    D Wakefield
    School of Pathology University of New South Wales, Department of Ophthalmology, St Vincent s Hospital, Sydney, Australia
    Clin Experiment Ophthalmol 28:103-6. 2000
    ..To demonstrate the safety and effectiveness of intravenous methylprednisolone (IVMP) in the treatment of uveitis in association with multiple sclerosis (MS)...
  7. doi request reprint Controversy: ocular sarcoidosis
    Denis Wakefield
    Faculty of Medicine, University of New South Wales, Kensington, Sydney, New South Wales, Australia
    Ocul Immunol Inflamm 18:5-9. 2010
    ....
  8. doi request reprint What is new HLA-B27 acute anterior uveitis?
    Denis Wakefield
    School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia
    Ocul Immunol Inflamm 19:139-44. 2011
    ..Salazopirine and methotrexate are effective in decreasing recurrent attacks. Biological agents such as anti-TNF and anti-CD20 therapy may be effective in refractory severe AU but are rarely required...
  9. doi request reprint The role of PAMPs and DAMPs in the pathogenesis of acute and recurrent anterior uveitis
    Denis Wakefield
    Laboratory of Ocular Immunology, Centre for Inflammation and Immunology, Faculty of Medicine University of New South Wales, Sydney, Australia
    Br J Ophthalmol 94:271-4. 2010
    ....
  10. ncbi request reprint Role and regulation of CXC-chemokines in acute experimental keratitis
    M L Xue
    Cooperative Research Centre for Eye Research and Technology, Cornea and Contact Lens Research Unit, The University of New South Wales, Sydney, NSW 2052, Australia
    Exp Eye Res 76:221-31. 2003
    ....
  11. ncbi request reprint The phenotype of limbal epithelial stem cells
    Edwin C Figueira
    Inflammatory Diseases Research Unit, University of New South Wales, Australia
    Invest Ophthalmol Vis Sci 48:144-56. 2007
    ..The purpose of this study was to identify phenotypic markers of human limbal stem cells in fetal and adult corneas...
  12. pmc Balance of pro- and anti-inflammatory cytokines correlates with outcome of acute experimental Pseudomonas aeruginosa keratitis
    A Thakur
    Cornea and Contact Lens Research Unit, Cooperative Research Centre for Eye Research and Technology, The University of New South Wales, Sydney, New South Wales 2052, Australia
    Infect Immun 70:2187-97. 2002
    ..These findings point to the therapeutic potential of rIL-1Ra protein in possible treatment strategies for bacterial keratitis...
  13. doi request reprint Stem cell activity in the developing human cornea
    Sarah B Davies
    Department of Pathology, School of Medical Sciences, Vision Science, University of New South Wales, Sydney, New South Wales 2052, Australia
    Stem Cells 27:2781-92. 2009
    ..This study expands our understanding of limbal niche development and opens new avenues for investigation...
  14. doi request reprint Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex
    Jeanie J Y Chui
    Department of Pathology, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia
    Invest Ophthalmol Vis Sci 51:2558-67. 2010
    ..In this study, the expression of LPS receptors in iris pigment epithelium (IPE) was determined...
  15. ncbi request reprint Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in the human lens: implications for cortical cataract formation
    Nitin H Sachdev
    Inflammation Research Unit, School of Pathology, University of New South Wales, Sydney, New South Wales, Australia
    Invest Ophthalmol Vis Sci 45:4075-82. 2004
    ..To evaluate the expression and activity of MMPs and TIMPs after cytokine and UV-B exposure in a human lens epithelial cell line...
  16. doi request reprint Ultraviolet radiation and the role of matrix metalloproteinases in the pathogenesis of ocular surface squamous neoplasia
    John Ng
    Inflammatory Diseases Research Unit, School of Medical Sciences, The University of New South Wales, Sydney, Australia
    Invest Ophthalmol Vis Sci 49:5295-306. 2008
    ....
  17. pmc The role of ultraviolet irradiation and heparin-binding epidermal growth factor-like growth factor in the pathogenesis of pterygium
    Timothy M Nolan
    Inflammation Research Unit, School of Medical Sciences, University of New South Wales, Sydney
    Am J Pathol 162:567-74. 2003
    ..We postulate that this growth factor is a major driving force in the development of pterygia and a means by which UV irradiation causes the pathogenesis of pterygium...
  18. ncbi request reprint Susac syndrome: microangiopathy of the retina, cochlea and brain
    V P Saw
    Department of Ophthalmology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    Clin Experiment Ophthalmol 28:373-81. 2000
    ..The underlying process is believed to be a small vessel vasculitis causing microinfarcts in the retina, brain and cochlea...
  19. doi request reprint Ultraviolet radiation-induced cytokines promote mast cell accumulation and matrix metalloproteinase production: potential role in cutaneous lupus erythematosus
    H Van Nguyen
    Infection and Inflammation Research Centre, Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Scand J Rheumatol 40:197-204. 2011
    ..To examine the role of mast cells (MCs), cytokines, and matrix metalloproteinases (MMPs) following ultraviolet B (UVB) radiation in cutaneous lupus erythematosus (CLE)...
  20. ncbi request reprint Expression of MMPs and TIMPs in human pterygia and cultured pterygium epithelial cells
    N Di Girolamo
    Inflammation Research Unit, School of Pathology, The University of New South Wales, Sydney, Australia
    Invest Ophthalmol Vis Sci 41:671-9. 2000
    ..In the current study the hypothesis was that MMPs and TIMPs may actively participate in the formation and progression of pterygia...
  21. ncbi request reprint Cognitive deficits in patients suffering from chronic fatigue syndrome, acute infective illness or depression
    U Vollmer-Conna
    Inflammation Research Unit, School of Pathology, University of New South Wales, Sydney, Australia
    Br J Psychiatry 171:377-81. 1997
    ....
  22. ncbi request reprint Production of pro-inflammatory cytokines correlates with the symptoms of acute sickness behaviour in humans
    U Vollmer-Conna
    Department of Human Behaviour, School of Psychiatry, University of New South Wales, Sydney 2052, Australia
    Psychol Med 34:1289-97. 2004
    ..The aim of this research was to examine human sickness behaviour and its immunological correlates in documented Epstein-Barr virus (EBV), Q fever or Ross River virus (RRV) infections...
  23. ncbi request reprint Screening for prolonged fatigue syndromes: validation of the SOFA scale
    D Hadzi-Pavlovic
    Mood Disorders Unit, Prince of Wales Hospital, Randwick, NSW, Australia
    Soc Psychiatry Psychiatr Epidemiol 35:471-9. 2000
    ....
  24. ncbi request reprint The role of IL-1beta in the regulation of IL-8 and IL-6 in human corneal epithelial cells during Pseudomonas aeruginosa colonization
    M L Xue
    Cooperative Research Centre for Eye Research and Technology, University of New South Wales, School of Optometry, Sydney, New South Wales, Australia
    Curr Eye Res 23:406-14. 2001
    ..The purpose of this study was to investigate whether IL-1beta regulates the expression of IL-6 and IL-8 in human corneal epithelial cells during Pseudomonas aeruginosa colonization...
  25. ncbi request reprint Active matrilysin (MMP-7) in human pterygia: potential role in angiogenesis
    N Di Girolamo
    Inflammation Research Unit, School of Pathology, University of New South Wales, Sydney, New South Wales, Australia
    Invest Ophthalmol Vis Sci 42:1963-8. 2001
    ..The purpose of this study was to determine the cellular distribution and activation status of matrilysin (MMP-7) in pterygia...
  26. ncbi request reprint Regulatory role of IL-1beta in the expression of IL-6 and IL-8 in human corneal epithelial cells during Pseudomonas aeruginosa colonization
    M L Xue
    Cooperative Research Centre for Eye Research and Technology, The University of New South Wales, Sydney, Australia
    Clin Experiment Ophthalmol 29:171-4. 2001
    ..In conclusion, P. aeruginosa-colonized HCE cells produced low levels of IL-1beta and high levels of IL-6 and IL-8. Neutralizing IL-1beta protein significantly downregulated the production of IL-8 and IL-6...
  27. pmc In vitro and in vivo expression of interstitial collagenase/MMP-1 by human mast cells
    N Di Girolamo
    Inflammation Research Unit, School of Pathology, The University of New South Wales, Sydney, Australia
    Dev Immunol 7:131-42. 2000
    ..Alternatively collagenase-1 production by mast cells may play a critical role in cell invasion and migration into sites of inflammation...
  28. ncbi request reprint Differential expression of matrix metalloproteinases and their tissue inhibitors at the advancing pterygium head
    N Di Girolamo
    Inflammation Research Unit, School of Pathology, University of New South Wales, Australia
    Invest Ophthalmol Vis Sci 41:4142-9. 2000
    ..The purpose of this study was to determine the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) at the advancing pterygium edge...
  29. ncbi request reprint A randomized, double-blind placebo-controlled trial of moclobemide in patients with chronic fatigue syndrome
    I B Hickie
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Clin Psychiatry 61:643-8. 2000
    ..To date, no medical or psychotropic therapies have provided clear symptomatic benefit...
  30. pmc Cultured human ocular surface epithelium on therapeutic contact lenses
    Nick Di Girolamo
    Inflammatory Diseases Research Unit, Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    Br J Ophthalmol 91:459-64. 2007
    ..This study was initiated after observation of some intriguing epithelial growth properties of contact lenses used as a bandage for patients after pterygium surgery...
  31. ncbi request reprint Changes in Toll-like receptor (TLR)-2 and TLR4 expression and function but not polymorphisms are associated with acute anterior uveitis
    John H Chang
    Inflammatory Diseases Research Unit, School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    Invest Ophthalmol Vis Sci 48:1711-7. 2007
    ..To investigate the expression and polymorphisms of Toll-like receptor (TLR)-2 and -4 in the peripheral neutrophils and monocytes of patients with acute anterior uveitis (AAU)...
  32. ncbi request reprint Postinfective fatigue syndrome is not associated with altered cytokine production
    Ute Vollmer-Conna
    School of Psychiatry, University of New South Wales, Sydney University, Sydney, Australia
    Clin Infect Dis 45:732-5. 2007
    ..No significant differences were found. Ongoing production of the cytokines examined does not play a role in postinfective fatigue syndrome...
  33. ncbi request reprint The role of substance P in the pathogenesis of pterygia
    Jeanie Chui
    Inflammatory Diseases Research Unit, Department of Pathology, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia
    Invest Ophthalmol Vis Sci 48:4482-9. 2007
    ..This hypothesis prompted an investigation of the role of the sensory neuropeptide substance P (SP) and its receptor (NK(1) receptor) in directing cell migration in pterygia that may explain the characteristic growth pattern...
  34. doi request reprint Localization of the low-affinity nerve growth factor receptor p75 in human limbal epithelial cells
    Nick Di Girolamo
    Inflammatory Diseases Research Unit, School of Medical Sciences, University of New South Wales, and Department of Ophthalmology, Prince of Wales Hospital, Sydney, NSW, Australia
    J Cell Mol Med 12:2799-811. 2008
    ..p75 may represent an additional ocular surface epithelial stem/progenitor cell signature gene...
  35. doi request reprint A contact lens-based technique for expansion and transplantation of autologous epithelial progenitors for ocular surface reconstruction
    Nick Di Girolamo
    Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia
    Transplantation 87:1571-8. 2009
    ..We report on the safe and efficacy of a unique autologous SC transfer technique that utilizes an Food and Drug Administration-approved contact lens (CL) as the SC substrate and carrier for patients with LSCD...
  36. doi request reprint Chitosan-vancomysin composite biomaterial as a laser activated surgical adhesive with regional antimicrobial activity
    L John R Foster
    Bio polymer Research Group, Centre for Advanced Macromolecular Design, School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia
    Biomacromolecules 11:3563-70. 2010
    ..6 ± 2 KPa. Thus, we have developed a laser-activated bioadhesive with the potential to close wounds while facilitating the prevention of microbial infection through local release of antibiotic targeted to the site of potential infection...
  37. doi request reprint The potential of the immunological markers of sarcoidosis in exhaled breath and peripheral blood as future diagnostic and monitoring techniques
    Hasib Ahmadzai
    Inflammation and Infection Research Centre, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia
    Inflammopharmacology 19:55-68. 2011
    ..This review explores the literature on the cytokine profiles of blood and bronchoalveolar lavage lymphocytes following ex vivo stimulation, as well as disease markers measured using the medium of EBC...
  38. ncbi request reprint UVB-mediated induction of cytokines and growth factors in pterygium epithelial cells involves cell surface receptors and intracellular signaling
    Nick Di Girolamo
    Inflammatory Diseases Research Unit, Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Invest Ophthalmol Vis Sci 47:2430-7. 2006
    ....
  39. pmc Epidermal growth factor receptor signaling is partially responsible for the increased matrix metalloproteinase-1 expression in ocular epithelial cells after UVB radiation
    Nick Di Girolamo
    Inflammatory Diseases Research Unit, Department of Pathology, School of Medical Sciences, Faculty of Medicine, The University of New South Wales, Sydney, 2052, Australia
    Am J Pathol 167:489-503. 2005
    ....
  40. ncbi request reprint Pathogenesis of pterygia: role of cytokines, growth factors, and matrix metalloproteinases
    Nick Di Girolamo
    Department of Pathology, Inflammatory Diseases Research Unit, School of Medical Sciences, University of New South Wales, Sydney 2052, Australia
    Prog Retin Eye Res 23:195-228. 2004
    ..In this review, the current knowledge on pterygium pathogenesis is summarised, highlighting recent developments. In addition, we provide novel data further demonstrating the complexity of this intriguing disease...
  41. ncbi request reprint UVB-mediated induction of interleukin-6 and -8 in pterygia and cultured human pterygium epithelial cells
    Nick Di Girolamo
    Inflammation Research Unit, School of Medical Sciences, Department of Pathology, Faculty of Medicine, University of New South Wales, Sydney, Australia
    Invest Ophthalmol Vis Sci 43:3430-7. 2002
    ..The hypothesis tested in the current study is that UV radiation modulates the expression of interleukin (IL)-6 and -8, which could promote the neovascularization and chronic inflammation regularly observed in pterygia...
  42. ncbi request reprint UVB-elicited induction of MMP-1 expression in human ocular surface epithelial cells is mediated through the ERK1/2 MAPK-dependent pathway
    Nick Di Girolamo
    University of New South Wales, Inflammation Research Unit, Department of Pathology, Sydney, New South Wales, Australia
    Invest Ophthalmol Vis Sci 44:4705-14. 2003
    ....
  43. ncbi request reprint Web-based self-assessments in pathology with Questionmark Perception
    Gary M Velan
    Department of Pathology, University of New South Wales, Sydney, Australia
    Pathology 34:282-4. 2002
    ..The potential of on-line formative self-assessments for postgraduate training and continuing education in pathology so far remains untapped...
  44. ncbi request reprint Virtual microscopy for learning and assessment in pathology
    Rakesh K Kumar
    Department of Pathology, University of New South Wales, Sydney, NSW 2052, Australia
    J Pathol 204:613-8. 2004
    ..We believe that the use of high-quality learning resources such as virtual slides can ensure that microscopic examination of tissues remains both meaningful and interesting...
  45. ncbi request reprint Proliferative effects of heparin-binding epidermal growth factor-like growth factor on pterygium epithelial cells and fibroblasts
    Timothy M Nolan
    Inflammation Research Unit, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Invest Ophthalmol Vis Sci 45:110-3. 2004
    ....
  46. ncbi request reprint Functional activity of plasma fibronectin in patients with diabetes mellitus
    N Di Girolamo
    Laboratory of Ocular Immunology, School of Pathology, University of New South Wales, Australia
    Diabetes 42:1606-13. 1993
    ..These results suggest that diabetic patients receiving insulin treatment show no modulation of plasma fibronectin function, despite raised levels of circulating glucose...
  47. pmc Expression and distribution of matrix metalloproteinases and their inhibitors in the human iris and ciliary body
    J Lan
    The Inflammation Research Unit, School of Medical Sciences, Department of Pathology, University of New South Wales, Sydney 2052, Australia
    Br J Ophthalmol 87:208-11. 2003
    ..To determine the expression and distribution of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the normal human iris and ciliary body...
  48. doi request reprint Otago Glaucoma Surgery Outcome Study: the pattern of expression of MMPs and TIMPs in bleb capsules surrounding Molteno implants
    Peter McCluskey
    Department of Ophthalmology, Liverpool Hospital, Sydney, Australia
    Invest Ophthalmol Vis Sci 50:2161-4. 2009
    ..To determine whether MMPs and TIMPs are present in the bleb wall of Molteno implants...
  49. pmc Idiopathic orbital inflammatory syndrome: clinical features and treatment outcomes
    B N Swamy
    Department of Ophthalmology, Liverpool Hospital, Liverpool NSW 2170, Australia
    Br J Ophthalmol 91:1667-70. 2007
    ..To characterise the clinical and pathological features of 24 patients with biopsy proven Idiopathic Orbital Inflammatory Syndrome (IOIS)...
  50. ncbi request reprint Mast cell accumulation and cytokine expression in the tight skin mouse model of scleroderma
    Hong Wei Wang
    School of Medical Sciences, The University of New South Wales, Sydney, Australia
    Exp Dermatol 14:295-302. 2005
    ..These results suggest that locally produced cytokines in Tsk skin influence mast cell accumulation in this animal model of human scleroderma...
  51. pmc Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study
    Ian Hickie
    Brain and Mind Research Institute, Sydney University, Sydney, NSW 2050, Australia
    BMJ 333:575. 2006
    ..To delineate the risk factors, symptom patterns, and longitudinal course of prolonged illnesses after a variety of acute infections...
  52. ncbi request reprint Acute anterior uveitis and HLA-B27
    John H Chang
    Laboratory of Ocular Immunology, Inflammatory Diseases Research Unit, School of Medical Sciences, University of New South Wales, Sydney Department of Ophthalmology, St Vincent s Hospital, Sydney
    Surv Ophthalmol 50:364-88. 2005
    ..Furthermore, to the ophthalmologist and the internist, HLA-B27-associated acute anterior uveitis is also of systemic importance due to its significant association with extraocular inflammatory diseases...
  53. ncbi request reprint Expression of toll-like receptor 4 and its associated lipopolysaccharide receptor complex by resident antigen-presenting cells in the human uvea
    John H Chang
    Laboratory of Ocular Immunology, Inflammatory Diseases Research Unit, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Invest Ophthalmol Vis Sci 45:1871-8. 2004
    ..To investigate the in vivo expression of toll-like receptor 4 (TLR4) and its associated lipopolysaccharide (LPS) receptor complex in the human eye...
  54. ncbi request reprint Human limbal epithelial progenitor cells express αvβ5-integrin and the interferon-inducible chemokine CXCL10/IP-10
    P Ordonez
    School of Medical Sciences, University of New South Wales, Sydney, Australia
    Stem Cell Res 11:888-901. 2013
    ..Knowledge of the niche's molecular composition and the genes expressed by its SC will facilitate isolation and maintenance of these cells for therapeutic purposes. ..
  55. doi request reprint The effect of mesenchymal stem cell conditioned media on corneal stromal fibroblast wound healing activities
    S L Watson
    Department of Pathology, School of Medical Sciences, University of New South Wales, Randwick, New South Wales, Australia
    Br J Ophthalmol 94:1067-73. 2010
    ..To investigate the effects of conditioned media from mesenchymal stem cells (MSC) on the wound healing activities of corneal stromal fibroblasts...
  56. pmc Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease
    J H Chang
    School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    Br J Ophthalmol 90:103-8. 2006
    ....
  57. ncbi request reprint Expression of macrophage migration inhibitory factor during Pseudomonas keratitis
    A Thakur
    Cooperative Research Centre for Eye Research and Technology, The University of New South Wales, Sydney, Australia
    Clin Experiment Ophthalmol 29:179-82. 2001
    ..High expression of MIF in the infected corneas suggests that it may have a role in the pathogenesis of corneal disease induced by invasive and cytotoxic strains of P. aeruginosa...
  58. ncbi request reprint Small intestinal mucosal immunity and morphometry in luminal overgrowth of indigenous gut flora
    S M Riordan
    Department of Gastroenterology, The Prince of Wales Hospital and School of Pathology, The University of New South Wales, Sydney, Australia
    Am J Gastroenterol 96:494-500. 2001
    ..Nonetheless, these would not be readily apparent during routine histological assessment. Old age independently influences duodenal IEL counts...
  59. ncbi request reprint An akinetic-rigid syndrome, depression, and stereotypies in a young man
    J W Lance
    Institute of Neurological Sciences, Prince of Wales Hospital, Sydney, Australia
    Mov Disord 13:835-44. 1998
    ..There was no response to L-dopa/cardopa treatment. A course of ECT was followed by a marked improvement in his condition. Attempts to stop ECT for more than a week have led to recurrence of his bradykinesia...
  60. ncbi request reprint Polymorphisms in Toll-like receptors-2 and -4 are not associated with disease manifestations in acute Q fever
    B Everett
    Centre for Infection and Inflammation Research, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia
    Genes Immun 8:699-702. 2007
    ..No correlation was demonstrated between these polymorphisms and susceptibility to Q fever, illness severity or illness course...
  61. ncbi request reprint What is chronic fatigue syndrome? Heterogeneity within an international multicentre study
    A Wilson
    University of New South Wales, Sydney, Australia
    Aust N Z J Psychiatry 35:520-7. 2001
    ..The validity of the subclasses was then tested against clinical data...
  62. ncbi request reprint Lens dislocation in Marfan syndrome: potential role of matrix metalloproteinases in fibrillin degradation
    Nitin H Sachdev
    Department of Ophthalmology, Prince of Wales Hospital, University of New South Wales, Randwick, Sydney, Australia
    Arch Ophthalmol 120:833-5. 2002
  63. ncbi request reprint Regulation of MMPs and TIMPs by IL-1beta during corneal ulceration and infection
    Mei Lang Xue
    Cooperative Research Centre for Eye Research and Technology and Cornea and Contact Lens Research Unit, School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia
    Invest Ophthalmol Vis Sci 44:2020-5. 2003
    ..This study was conducted to investigate the role of IL-1beta in the regulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in a mouse model of experimental keratitis and corneal injury...
  64. ncbi request reprint Uveitis: a global perspective
    John Hyun Min Chang
    Inflammation Research Unit, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia
    Ocul Immunol Inflamm 10:263-79. 2002
    ..To study the patterns of uveitis in various geographic regions...
  65. doi request reprint Cytokine polymorphisms have a synergistic effect on severity of the acute sickness response to infection
    Ute Vollmer-Conna
    School of Psychiatry and 2Centre for Infection and Inflammation Research, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Clin Infect Dis 47:1418-25. 2008
    ..The genetic determinants of severity of the acute sickness response have not previously been explored...
  66. ncbi request reprint Prolonged illness after infectious mononucleosis is associated with altered immunity but not with increased viral load
    Barbara Cameron
    School of Medical Sciences, Inflammatory Diseases Research Unit, University of New South Wales, Sydney, Australia
    J Infect Dis 193:664-71. 2006
    ..We examined the relationships between clinical course, number of viral copies, and immunological parameters in a prospective cohort of subjects with recent IM...
  67. pmc The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer
    A Hettiaratchi
    Inflammatory Diseases Research Unit, Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Br J Cancer 96:783-92. 2007
    ..Although our results were unexpected, given that this genotype is associated with enhanced MMP-1 transcriptional activity, they are consistent with recent data highlighting the anti-tumorigenic properties of MMPs...
  68. ncbi request reprint Human mast cell-derived gelatinase B (matrix metalloproteinase-9) is regulated by inflammatory cytokines: role in cell migration
    Nick Di Girolamo
    Inflammatory Diseases Research Unit, School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    J Immunol 177:2638-50. 2006
    ....
  69. ncbi request reprint Epidemiology of uveitis
    Denis Wakefield
    School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    Int Ophthalmol Clin 45:1-13. 2005
  70. ncbi request reprint Gene expression correlates of postinfective fatigue syndrome after infectious mononucleosis
    Barbara Cameron
    School of Medical Sciences, University of New South Wales, Sydney, Australia
    J Infect Dis 196:56-66. 2007
    ..Infectious mononucleosis (IM) commonly triggers a protracted postinfective fatigue syndrome (PIFS) of unknown pathogenesis...
  71. ncbi request reprint A critical role for CCL2 and CCL3 chemokines in the regulation of polymorphonuclear neutrophils recruitment during corneal infection in mice
    Mei Lang Xue
    Vision Cooperative Research Centre, Sydney, NSW, Australia
    Immunol Cell Biol 85:525-31. 2007
    ..Our findings provide strong evidence that CCL2 and CCL3 are critical regulators of PMN recruitment, and may lead to therapeutic strategies via targeting of the CC chemokines, CCL2 and CCL3, in the management of P. aeruginosa keratitis...
  72. ncbi request reprint The pathogenesis of pterygium: current concepts and their therapeutic implications
    Jeanie Chui
    Inflammatory Diseases Research Unit, Department of Pathology, University of New South Wales, and Department of Ophthalmology, University of New South Wales at Prince of Wales Hospital, Sydney, Australia
    Ocul Surf 6:24-43. 2008
    ..Therapeutic options for pterygium are discussed based on the mechanisms that perpetuate its growth...
  73. ncbi request reprint Methotrexate therapy for ocular cicatricial pemphigoid
    Peter McCluskey
    Department of Ophthalmology, St Vincent s Hospital, Sydney, Australia
    Ophthalmology 111:796-801. 2004
    ..To report the use of methotrexate therapy as first-line systemic therapy in the treatment of ocular-cicatricial pemphigoid and drug-induced ocular-cicatricial pemphigoid...
  74. ncbi request reprint Isolated ectopia lentis: potential role of matrix metalloproteinases in fibrillin degradation
    Nitin H Sachdev
    Dept of Ophthalmology, Prince of Wales Hospital, University of New South Wales, Randwick, Sydney, Australia
    Arch Ophthalmol 122:111-4. 2004
  75. ncbi request reprint The future of medical museums: threatened but not extinct
    Denis Wakefield
    Med J Aust 187:380-1. 2007
  76. ncbi request reprint Paediatric uveitis in Sydney
    John H Chang
    Clin Experiment Ophthalmol 33:336; author reply 336-7. 2005
  77. ncbi request reprint Lens dislocation in Marfan syndrome and UV-B light exposure
    Nitin Sachdev
    Arch Ophthalmol 121:585. 2003