J C Vickers

Summary

Affiliation: University of Tasmania
Country: Australia

Publications

  1. ncbi request reprint The cause of neuronal degeneration in Alzheimer's disease
    J C Vickers
    Neurobiology Laboratory, School of Medicine, Faculty of Health Sciences, University of Tasmania, Hobart, Australia
    Prog Neurobiol 60:139-65. 2000
  2. pmc Measuring dementia carers' unmet need for services--an exploratory mixed method study
    Christine Stirling
    Wicking Dementia Research and Education Centre, Menzies Research Institute, University of Tasmania, Private Bag 121, Hobart Tas, 7000 Australia
    BMC Health Serv Res 10:122. 2010
  3. ncbi request reprint A vaccine against Alzheimer's disease: developments to date
    James C Vickers
    Discipline of Pathology, University of Tasmania, GPO Box 252 29, Hobart, Tasmania 7001, Australia
    Drugs Aging 19:487-94. 2002
  4. ncbi request reprint Direct determination of the proportion of intra- and extra-cellular neocortical neurofibrillary tangles in Alzheimer's disease
    James C Vickers
    Discipline of Pathology, School of Medicine, University of Tasmania, 43 Collins St, GPO Box 252 29, Tasmania Hobart 7001, Australia
    Brain Res 971:135-7. 2003
  5. ncbi request reprint The apolipoprotein epsilon4 gene is associated with elevated risk of normal tension glaucoma
    James C Vickers
    School of Medicine, University of Tasmania, Hobart, Tasmania, Australia
    Mol Vis 8:389-93. 2002
  6. doi request reprint Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system
    James C Vickers
    NeuroRepair Group and Wicking Dementia Research and Education Centre, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Brain Res Bull 80:217-23. 2009
  7. doi request reprint Neuron-glia interactions underlie ALS-like axonal cytoskeletal pathology
    A E King
    NeuroRepair Group and Wicking Dementia Research and Education Centre, Menzies Research Institute, Hobart, Tasmania 7000, Australia
    Neurobiol Aging 32:459-69. 2011
  8. ncbi request reprint The morphological phenotype of beta-amyloid plaques and associated neuritic changes in Alzheimer's disease
    T C Dickson
    Discipline of Pathology, Clinical School, University of Tasmania, 43 Collins St, 7000, Hobart, Tasmania, Australia
    Neuroscience 105:99-107. 2001
  9. ncbi request reprint Olfactory ensheathing cells promote neurite sprouting of injured axons in vitro by direct cellular contact and secretion of soluble factors
    R S Chung
    NeuroRepair Group, School of Medicine, University of Tasmania, Private Bag 58, Hobart, Tasmania 7001, Australia
    Cell Mol Life Sci 61:1238-45. 2004
  10. ncbi request reprint Excitotoxicity mediated by non-NMDA receptors causes distal axonopathy in long-term cultured spinal motor neurons
    A E King
    NeuroRepair Group, Menzies Research Institute, Hobart, Tasmania 7000, Australia
    Eur J Neurosci 26:2151-9. 2007

Detail Information

Publications53

  1. ncbi request reprint The cause of neuronal degeneration in Alzheimer's disease
    J C Vickers
    Neurobiology Laboratory, School of Medicine, Faculty of Health Sciences, University of Tasmania, Hobart, Australia
    Prog Neurobiol 60:139-65. 2000
    ..Therapeutically, inhibition of the neuronal reaction to physical trauma may be a useful neuroprotective strategy in the earliest stages of Alzheimer's disease...
  2. pmc Measuring dementia carers' unmet need for services--an exploratory mixed method study
    Christine Stirling
    Wicking Dementia Research and Education Centre, Menzies Research Institute, University of Tasmania, Private Bag 121, Hobart Tas, 7000 Australia
    BMC Health Serv Res 10:122. 2010
    ..This study used Bradshaw's taxonomy of need to explore the link between measures of carer burden (normative need), service use (expressed need), and carer's stated need (felt need)...
  3. ncbi request reprint A vaccine against Alzheimer's disease: developments to date
    James C Vickers
    Discipline of Pathology, University of Tasmania, GPO Box 252 29, Hobart, Tasmania 7001, Australia
    Drugs Aging 19:487-94. 2002
    ..The promise of this novel approach to AD treatment and/or prevention has led to initial human trials utilising beta-amyloid as an immunogen...
  4. ncbi request reprint Direct determination of the proportion of intra- and extra-cellular neocortical neurofibrillary tangles in Alzheimer's disease
    James C Vickers
    Discipline of Pathology, School of Medicine, University of Tasmania, 43 Collins St, GPO Box 252 29, Tasmania Hobart 7001, Australia
    Brain Res 971:135-7. 2003
    ..Thus, most neocortical tangles in Alzheimer's disease are intracellular and may not be the principal cause of neocortical cell loss...
  5. ncbi request reprint The apolipoprotein epsilon4 gene is associated with elevated risk of normal tension glaucoma
    James C Vickers
    School of Medicine, University of Tasmania, Hobart, Tasmania, Australia
    Mol Vis 8:389-93. 2002
    ..Thus, we have investigated the association of inheritance of apolipoprotein E allelic isoforms (epsilon2, [epsilon]3, and epsilon4) with relative risk for different forms of glaucoma...
  6. doi request reprint Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system
    James C Vickers
    NeuroRepair Group and Wicking Dementia Research and Education Centre, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Brain Res Bull 80:217-23. 2009
    ..The identification of a degenerative process initiated in the axon may provide new therapeutic targets for early intervention to inhibit the grim outcomes related to the progression of these diseases...
  7. doi request reprint Neuron-glia interactions underlie ALS-like axonal cytoskeletal pathology
    A E King
    NeuroRepair Group and Wicking Dementia Research and Education Centre, Menzies Research Institute, Hobart, Tasmania 7000, Australia
    Neurobiol Aging 32:459-69. 2011
    ..These data provide strong evidence for the involvement of non-neuronal cells in axonal dysfunction in ALS. This cell culture model may be of benefit for the development of therapeutic interventions directed at axonal preservation...
  8. ncbi request reprint The morphological phenotype of beta-amyloid plaques and associated neuritic changes in Alzheimer's disease
    T C Dickson
    Discipline of Pathology, Clinical School, University of Tasmania, 43 Collins St, 7000, Hobart, Tasmania, Australia
    Neuroscience 105:99-107. 2001
    ..There data indicate key pathological changes that may be subject to therapeutic intervention to slow the progression of Alzheimer's disease...
  9. ncbi request reprint Olfactory ensheathing cells promote neurite sprouting of injured axons in vitro by direct cellular contact and secretion of soluble factors
    R S Chung
    NeuroRepair Group, School of Medicine, University of Tasmania, Private Bag 58, Hobart, Tasmania 7001, Australia
    Cell Mol Life Sci 61:1238-45. 2004
    ..Our findings provide new insight into the ability of OECs to promote axonal regeneration, and also indicate potential targets for manipulation of these cells to enhance their restorative ability...
  10. ncbi request reprint Excitotoxicity mediated by non-NMDA receptors causes distal axonopathy in long-term cultured spinal motor neurons
    A E King
    NeuroRepair Group, Menzies Research Institute, Hobart, Tasmania 7000, Australia
    Eur J Neurosci 26:2151-9. 2007
    ..These data provide a strong link between excitotoxicity and the selective pattern of axonopathy of lower motor neurons that underlies neuronal dysfunction in ALS...
  11. ncbi request reprint Metallothionein expression by NG2 glial cells following CNS injury
    R S Chung
    NeuroRepair Group, Menzies Research Institute, University of Tasmania, Private Bag 58, Hobart, Tasmania, 7001, Australia
    Cell Mol Life Sci 64:2716-22. 2007
    ..Our data suggest that expression of MT by NG2 glial cells may contribute to the overall permissiveness of these cells to axon regeneration...
  12. ncbi request reprint Olfactory ensheathing cells promote collateral axonal branching in the injured adult rat spinal cord
    M I Chuah
    NeuroRepair Group, School of Medicine, University of Tasmania, Hobart, Tasmania 7001, Australia
    Exp Neurol 185:15-25. 2004
    ..003), while a trend for increased collateral branches was observed in rats that received encapsulated ECs (P=0.07)...
  13. ncbi request reprint Cellular dynamics underlying regeneration of damaged axons differs from initial axon development
    C A Blizzard
    NeuroRepair Group, Menzies Research Institute, University of Tasmania, Private Bag 29, Hobart, Tasmania, Australia 7000
    Eur J Neurosci 26:1100-8. 2007
    ..These intrinsic differences may account for the inability of post-traumatic locally sprouting axons to make accurate pathway decisions and successfully respond to trauma...
  14. ncbi request reprint Cytoskeletal and morphological alterations underlying axonal sprouting after localized transection of cortical neuron axons in vitro
    Jyoti A Chuckowree
    Discipline of Pathology, Faculty of Health Sciences, University of Tasmania, Hobart, Tasmania, 7000, Australia
    J Neurosci 23:3715-25. 2003
    ..Our results indicate that the axons of cortical neurons have an intrinsic ability to sprout after transection, and similar cytoskeletal dynamics underlie neurite development and postinjury axonal sprouting...
  15. ncbi request reprint Alpha-synuclein is upregulated in neurones in response to chronic oxidative stress and is associated with neuroprotection
    M C Quilty
    NeuroRepair Group, University of Tasmania, Private Bag 29, Hobart, Tasmania 7001, Australia
    Exp Neurol 199:249-56. 2006
    ..These data indicate that increased alpha-synuclein content is associated with neuroprotection from relatively low levels of oxidative stress...
  16. ncbi request reprint Cyclosporin-A treatment attenuates delayed cytoskeletal alterations and secondary axotomy following mild axonal stretch injury
    J A Staal
    NeuroRepair Group, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Dev Neurobiol 67:1831-42. 2007
    ..In summary, these results suggest that cyclosporin-A reduces progressive cytoskeletal damage and secondary axotomy following transient axonal stretch injury in vitro...
  17. ncbi request reprint Localization of alpha-, beta-, and gamma-synuclein during neuronal development and alterations associated with the neuronal response to axonal trauma
    M C Quilty
    NeuroRepair Group, University of Tasmania, 7000, Hobart, Tasmania, Australia
    Exp Neurol 182:195-207. 2003
    ..In addition, synuclein proteins accumulate rapidly in damaged axons and may have a role in regenerative sprouting...
  18. ncbi request reprint Rho kinase activates ezrin-radixin-moesin (ERM) proteins and mediates their function in cortical neuron growth, morphology and motility in vitro
    Matilda A Haas
    NeuroRepair Group, University of Tasmania, Hobart, Australia
    J Neurosci Res 85:34-46. 2007
    ..Thus, Rho kinase is an important activator of ERMs in mediating specific neuronal functions...
  19. ncbi request reprint Binding partners L1 cell adhesion molecule and the ezrin-radixin-moesin (ERM) proteins are involved in development and the regenerative response to injury of hippocampal and cortical neurons
    Matilda A Haas
    NeuroRepair Group, University of Tasmania, 43 Collins Street, Hobart, Tasmania, 7000, Australia
    Eur J Neurosci 20:1436-44. 2004
    ..We have demonstrated that L1 and the ERM proteins are involved in the neuronal response to injury, and that neurons derived from the hippocampus and cortex may have different post-injury regenerative neurite sprouting abilities...
  20. doi request reprint Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease
    Adele Woodhouse
    Wicking Dementia Research and Education Centre and NeuroRepair Group, Menzies Research Institute, Private Bag 29, Hobart, TAS, 7001, Australia
    Acta Neuropathol 117:19-29. 2009
    ..These differences in cytoskeletal pathology in PS1 cases suggest an accelerated rate of neuritic pathology development, potentially due to mutant PS1 influencing multiple pathogenic pathways...
  21. ncbi request reprint The cellular mechanism underlying neuronal degeneration in glaucoma: parallels with Alzheimer's disease
    J C Vickers
    Division of Pathology, Clinical School, University of Tasmania, Hobart, Australia
    Aust N Z J Ophthalmol 25:105-9. 1997
    ....
  22. ncbi request reprint Localization of glutamate receptors in developing cortical neurons in culture and relationship to susceptibility to excitotoxicity
    A E King
    NeuroRepair Group, University of Tasmania, Hobart, Tasmania 7001, Australia
    J Comp Neurol 498:277-94. 2006
    ..These data also suggest that excitotoxicity can be mediated through extrasynaptic receptor subunit complexes along dendrites...
  23. ncbi request reprint Alterations in neurofilaments associated with reactive brain changes and axonal sprouting following acute physical injury to the rat neocortex
    C E King
    Neurodegeneration Research Laboratory, Discipline of Pathology, Faculty of Health Sciences, University of Tasmania, 43 Collins Street, Hobart, Tasmania 7000, Australia
    Neuropathol Appl Neurobiol 27:115-26. 2001
    ..These data also support a role for neurofilaments in axonal sprouting following brain injury...
  24. ncbi request reprint No difference in expression of apoptosis-related proteins and apoptotic morphology in control, pathologically aged and Alzheimer's disease cases
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, Private Bag 29, University of Tasmania, Hobart, Tasmania 7001, Australia
    Neurobiol Dis 22:323-33. 2006
    ..Apoptosis may not play a major role in the pathogenesis of neuronal degeneration of AD...
  25. doi request reprint Axonal shearing in mature cortical neurons induces attempted regeneration and the reestablishment of neurite polarity
    Catherine A Blizzard
    Wicking Dementia Research and Education Centre and NeuroRepair Group, Menzies Research Institute, University of Tasmania, Private Bag 29, Hobart, Tasmania, Australia 7000
    Brain Res 1300:24-36. 2009
    ..These results may aid in defining the cellular basis of neuronal structural plasticity and defining the role of astrocyte reactivity in the response to trauma...
  26. doi request reprint Focal demyelination in Alzheimer's disease and transgenic mouse models
    Stanislaw Mitew
    NeuroRepair Group, Wicking Dementia Research and Education Centre, Menzies Research Institute, University of Tasmania, Hobart, TAS 7000, Australia
    Acta Neuropathol 119:567-77. 2010
    ..We suggest that such plaque-associated focal demyelination of the cortical grey matter might impair cortical processing, and may also be associated with aberrant axonal sprouting that underlies dystrophic neurite formation...
  27. ncbi request reprint Metallothionein-IIA promotes initial neurite elongation and postinjury reactive neurite growth and facilitates healing after focal cortical brain injury
    Roger S Chung
    NeuroRepair Group, School of Medicine, University of Tasmania, Hobart, Tasmania 7001, Australia
    J Neurosci 23:3336-42. 2003
    ..These results are discussed in relation to a possible physiological role of metallothioneins in the brain, as well as in a therapeutic context...
  28. pmc Redefining the role of metallothionein within the injured brain: extracellular metallothioneins play an important role in the astrocyte-neuron response to injury
    Roger S Chung
    NeuroRepair Group, Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7001, Australia
    J Biol Chem 283:15349-58. 2008
    ..This unsuspected action of MT represents a novel paradigm of astrocyte-neuronal interaction after injury and may have implications for the development of MT-based therapeutic agents...
  29. ncbi request reprint Dystrophic neurites in TgCRND8 and Tg2576 mice mimic human pathological brain aging
    Adele Woodhouse
    NeuroRepair Group, Menzies Research Institute, 43 Collins Street, Hobart, 7001 Tasmania, Australia
    Neurobiol Aging 30:864-74. 2009
    ..These results suggest that neuronal pathology in these mice represent an accurate and valuable model for understanding, and developing treatments for, the early brain changes of AD...
  30. doi request reprint Multiple views reveal the complexity of dementia diagnosis
    Andrew L Robinson
    School of Nursing and Midwifery, University of Tasmania, Tasmania, Australia
    Australas J Ageing 27:183-8. 2008
    ..To reveal views about dementia diagnosis derived from a larger study of information needs of carers of people with dementia in Tasmania, Australia...
  31. doi request reprint Disruption of the ubiquitin proteasome system following axonal stretch injury accelerates progression to secondary axotomy
    Jerome A Staal
    NeuroRepair Group, Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7001, Australia
    J Neurotrauma 26:781-8. 2009
    ..Protein ubiquitination in the axon may therefore have a protective role relative to the diffuse axonal changes that follow traumatic brain injury...
  32. doi request reprint Initial calcium release from intracellular stores followed by calcium dysregulation is linked to secondary axotomy following transient axonal stretch injury
    Jerome A Staal
    NeuroRepair Group and Wicking Dementia Research and Education Centre, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    J Neurochem 112:1147-55. 2010
    ....
  33. pmc The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons
    Roger S Chung
    NeuroRepair Group, Menzies Research Institute, University of Tasmania, Hobart, Australia
    PLoS ONE 5:e12030. 2010
    ..A major pathological hallmark of AD is the deposition of insoluble extracellular beta-amyloid (Abeta) plaques. There are compelling data suggesting that Abeta aggregation is catalysed by reaction with the metals zinc and copper...
  34. ncbi request reprint Acute reactive and regenerative changes in mature cortical axons following injury
    Tracey C Dickson
    NeuroRepair Group, School of Medicine, University of Tasmania, Tasmania, Australia
    Neuroreport 18:283-8. 2007
    ..These results indicate that damaged mature axons have an intrinsic capacity to react adaptively and attempt regeneration...
  35. ncbi request reprint Vaccination strategies for Alzheimer's disease: A new hope?
    Adele Woodhouse
    School of Medicine, NeuroRepair Group, University of Tasmania, Hobart, Tasmania, Australia
    Drugs Aging 24:107-19. 2007
    ..The vigour of international research on immunotherapy for AD provides significant hope for a strong therapeutic lead for the escalating number of individuals who will develop this otherwise incurable condition...
  36. ncbi request reprint Protective role of metallothioneins in the injured mammalian brain
    Adrian K West
    NeuroRepair Group, University of Tasmania, Hobart, Australia
    Rev Neurosci 15:157-66. 2004
    ....
  37. ncbi request reprint alpha-Internexin immunoreactivity reflects variable neuronal vulnerability in Alzheimer's disease and supports the role of the beta-amyloid plaques in inducing neuronal injury
    Tracey C Dickson
    NeuroRepair Group, University of Tasmania, Hobart, Tasmania, 7000, Australia
    Neurobiol Dis 18:286-95. 2005
    ..These results implicate the expression of specific intermediate filament proteins in a distinct hierarchy of differential neuronal vulnerability to AD...
  38. ncbi request reprint Mild axonal stretch injury in vitro induces a progressive series of neurofilament alterations ultimately leading to delayed axotomy
    Roger S Chung
    NeuroRepair Group, School of Medicine, University of Tasmania, Hobart, Tasmania, Australia
    J Neurotrauma 22:1081-91. 2005
    ..Hence, it is possible that the cytoskeletal characteristics that we have used in this study may be useful parameters for discriminating between mildly and severely injured axons following TBI...
  39. ncbi request reprint Neuron-glia communication: metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury
    Roger S Chung
    NeuroRepair Group, School of Medicine, University of Tasmania, Hobart, Tasmania, Australia
    J Neurochem 88:454-61. 2004
    ..Based upon recent reports indicating that MT-I/-II are major neuroprotective proteins within the brain, our results provide further evidence that MT-I/-II plays an important role in the cellular response to neuronal injury...
  40. ncbi request reprint Cytoplasmic cytochrome c immunolabelling in dystrophic neurites in Alzheimer's disease
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, University of Tasmania, Private Bag 29, Hobart, TAS, 7001 Australia
    Acta Neuropathol 112:429-37. 2006
    ..Although cytochrome c release is indicative of the activation of the intrinsic apoptotic pathway, cytoplasmic cytochrome c may also indicate mitochondrial damage or dysfunction...
  41. ncbi request reprint Identification and characterization of a population of motile neurons in long-term cortical culture
    Matilda A Haas
    NeuroRepair Group, University of Tasmania, Hobart, Tasmania, Australia
    Cell Motil Cytoskeleton 64:274-87. 2007
    ..These studies provide new information on the structurally dynamic features of subsets of neurons...
  42. ncbi request reprint Glutamate induces rapid loss of axonal neurofilament proteins from cortical neurons in vitro
    Roger S Chung
    NeuroRepair Group, School of Medicine, University of Tasmania, Private Bag 58, Hobart, Tasmania 7001, Australia
    Exp Neurol 193:481-8. 2005
    ..This work suggests that excitotoxicity triggers a progressive pathway of cytoskeletal degeneration within axons, initially characterised by the loss of neurofilament proteins...
  43. ncbi request reprint Metallothionein biology in the ageing and neurodegenerative brain
    J Dittmann
    NeuroRepair Group, School of Medicine, University of Tasmania, Tasmania 7001 Australia
    Neurotox Res 7:87-93. 2005
    ....
  44. ncbi request reprint Magnocellular and parvocellular visual pathways are both affected in a macaque monkey model of glaucoma
    J C Vickers
    Division of Pathology, Clinical School, University of Tasmania, Hobart, Australia
    Aust N Z J Ophthalmol 25:239-43. 1997
    ..Neurochemical changes in nerve cells were investigated in the lateral geniculate nucleus (LGN) and primary visual cortex of macaque monkeys with experimentally induced glaucoma...
  45. ncbi request reprint Spinal cord tissue affects ensheathing cell proliferation and apoptosis
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, University of Tasmania, Private Bag 24, Hobart, Tasmania 7001, Australia
    Neuroreport 16:737-40. 2005
    ..These results suggest that delaying transplantation after spinal cord injury may be beneficial to ensheathing cell survival...
  46. ncbi request reprint Intrinsic regenerative ability of mature CNS neurons
    Jyoti A Chuckowree
    University of Tasmania, Hobart, Tasmania, Australia
    Neuroscientist 10:280-5. 2004
    ....
  47. ncbi request reprint Morphologically distinct plaque types differentially affect dendritic structure and organisation in the early and late stages of Alzheimer's disease
    Paul A Adlard
    Discipline of Pathology, University of Tasmania, Hobart, Austrtalia
    Acta Neuropathol 103:377-83. 2002
    ....
  48. ncbi request reprint Olfactory ensheathing cell phenotype following implantation in the lesioned spinal cord
    E Woodhall
    NeuroRepair Group, University of Tasmania, Private Bag 24, Hobart, Tasmania 7001, Australia
    Cell Mol Life Sci 60:2241-53. 2003
    ..Unlike oligodendrocytes, OECs expressed Nogo-66 receptor (NgR) mRNA. Implanted OECs upregulated Nogo-A and -B, but downregulated Nogo-ABC and NgR...
  49. ncbi request reprint Does beta-amyloid plaque formation cause structural injury to neuronal processes?
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, University of Tasmania, Australia
    Neurotox Res 7:5-15. 2005
    ..Identification of the key neuronal alterations underlying the pathology of Alzheimer's disease may provide new avenues for therapeutic intervention...
  50. ncbi request reprint Metallothionein-III inhibits initial neurite formation in developing neurons as well as postinjury, regenerative neurite sprouting
    R S Chung
    NeuroRepair Group, University of Tasmania, P O Box 252 58, Hobart, Tasmania 7001, Australia
    Exp Neurol 178:1-12. 2002
    ..Based on these results, we propose that MT-III, in the presence of brain extract, is a potent inhibitor of neurite sprouting, and may be involved in abnormal sprouting potentially underlying both AD and epilepsy...
  51. ncbi request reprint Positional effects of presenilin-1 mutations on tau phosphorylation in cortical plaques
    Claire E Shepherd
    Prince of Wales Medical Research Institute, Randwick, 2031 Sydney, Australia
    Neurobiol Dis 15:115-9. 2004
    ..These findings suggest that PS-1 mutations increase tau deposition while mutation-specific cellular responses determine phosphorylation events and may influence cell death mechanisms...
  52. ncbi request reprint Annular alpha-synuclein species from purified multiple system atrophy inclusions
    Dean L Pountney
    Department of Human Physiology, Flinders University, Adelaide, Australia
    J Neurochem 90:502-12. 2004
    ....