R F Uren

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi request reprint Patterns of lymphatic drainage from the skin in patients with melanoma
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, 100 Carillon Avenue, Newtown, Sydney, New South Wales 2042, Australia
    J Nucl Med 44:570-82. 2003
  2. ncbi request reprint Lymphatic drainage of the skin
    Roger F Uren
    Divisions of Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, The Department of Medicine, The University of Sydney, Sydney, and The Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Ann Surg Oncol 11:179S-85S. 2004
  3. ncbi request reprint Metastatic occlusion of a lymphatic collecting vessel in a patient with cutaneous melanoma and clinically normal lymph nodes
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, Newton, NSW, Australia
    Clin Nucl Med 32:312-3. 2007
  4. ncbi request reprint The reproducibility in routine clinical practice of sentinel lymph node identification by pre-operative lymphoscintigraphy in patients with cutaneous melanoma
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre and Discipline of Medicine, The University of Sydney, Sydney, NSW, Australia
    Ann Surg Oncol 14:899-905. 2007
  5. ncbi request reprint The role of lymphoscintigraphy in the detection of lymph node drainage in melanoma
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, 100 Carillon Avenue, Newtown, NSW 2042, Australia
    Surg Oncol Clin N Am 15:285-300. 2006
  6. ncbi request reprint The utility of ultrasound in patients with melanoma
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, Suite 206, RPAH Medical Center, 100 Carillon Avenue, Newtown, NSW 2042, Sydney, Australia
    Expert Rev Anticancer Ther 7:1633-42. 2007
  7. ncbi request reprint Sentinel lymph node biopsy in patients with melanoma and breast cancer
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, Royal Prince Alfred Hospital Medical Centre, Newtown, New South Wales, Australia
    Intern Med J 31:547-53. 2001
  8. ncbi request reprint Interval nodes: the forgotten sentinel nodes in patients with melanoma
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, 100 Carillon Ave, Suite 206, Newtown, New South Wales 2042, Australia
    Arch Surg 135:1168-72. 2000
  9. ncbi request reprint High-resolution ultrasound to diagnose melanoma metastases in patients with clinically palpable lymph nodes
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, Missenden Medical Centre, Camperdown, NSW, Australia
    Australas Radiol 43:148-52. 1999
  10. ncbi request reprint Direct lymphatic drainage from a melanoma on the back to paravertebral lymph nodes in the thorax
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, Missenden Medical Centre, Camperdown, New South Wales, Australia
    Clin Nucl Med 24:388-9. 1999

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Patterns of lymphatic drainage from the skin in patients with melanoma
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, 100 Carillon Avenue, Newtown, Sydney, New South Wales 2042, Australia
    J Nucl Med 44:570-82. 2003
    ..Micrometastatic disease can be present in any sentinel node regardless of its location, and for the SLNB technique to be accurate, all true sentinel nodes must be biopsied in every patient...
  2. ncbi request reprint Lymphatic drainage of the skin
    Roger F Uren
    Divisions of Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, The Department of Medicine, The University of Sydney, Sydney, and The Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Ann Surg Oncol 11:179S-85S. 2004
    ..Because micrometastatic disease can be present in any SN regardless of its location, all true SNs must be biopsied. LS is an important first step to ensure this goal is achieved...
  3. ncbi request reprint Metastatic occlusion of a lymphatic collecting vessel in a patient with cutaneous melanoma and clinically normal lymph nodes
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, Newton, NSW, Australia
    Clin Nucl Med 32:312-3. 2007
  4. ncbi request reprint The reproducibility in routine clinical practice of sentinel lymph node identification by pre-operative lymphoscintigraphy in patients with cutaneous melanoma
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre and Discipline of Medicine, The University of Sydney, Sydney, NSW, Australia
    Ann Surg Oncol 14:899-905. 2007
    ..These results indicate that in routine clinical practice LS is a highly reproducible procedure to locate and radiolabel the SLNs prior to biopsy in patients with melanoma...
  5. ncbi request reprint The role of lymphoscintigraphy in the detection of lymph node drainage in melanoma
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, 100 Carillon Avenue, Newtown, NSW 2042, Australia
    Surg Oncol Clin N Am 15:285-300. 2006
    ..In this way, lymphoscintigraphy has a direct beneficial impact on the surgical management of patients who have melanoma...
  6. ncbi request reprint The utility of ultrasound in patients with melanoma
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, Suite 206, RPAH Medical Center, 100 Carillon Avenue, Newtown, NSW 2042, Sydney, Australia
    Expert Rev Anticancer Ther 7:1633-42. 2007
    ..In the future the use of ultrasound contrast agents may improve the sensitivity of ultrasound in the detection of very small metastatic deposits...
  7. ncbi request reprint Sentinel lymph node biopsy in patients with melanoma and breast cancer
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, Royal Prince Alfred Hospital Medical Centre, Newtown, New South Wales, Australia
    Intern Med J 31:547-53. 2001
    ..A further advantage of lyamphatic mapping is that drainage to sentinel nodes in unusual locations is identified, leading to more accurate nodal staging than could be achieved with routine dissection of the closest node field...
  8. ncbi request reprint Interval nodes: the forgotten sentinel nodes in patients with melanoma
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, 100 Carillon Ave, Suite 206, Newtown, New South Wales 2042, Australia
    Arch Surg 135:1168-72. 2000
    ..If drainage to such interval nodes is ignored by the surgeon during sentinel node biopsy, metastatic melanoma will be missed in some patients...
  9. ncbi request reprint High-resolution ultrasound to diagnose melanoma metastases in patients with clinically palpable lymph nodes
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, Missenden Medical Centre, Camperdown, NSW, Australia
    Australas Radiol 43:148-52. 1999
    ..A normal ultrasound finding does not exclude micrometastases, but a lymph node showing the two key ultrasound features aforementioned is highly likely to contain metastatic disease and should be treated accordingly...
  10. ncbi request reprint Direct lymphatic drainage from a melanoma on the back to paravertebral lymph nodes in the thorax
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, Missenden Medical Centre, Camperdown, New South Wales, Australia
    Clin Nucl Med 24:388-9. 1999
    ..There was also drainage directly to the right groin and via a series of interval nodes to the right axilla. Knowledge of the presence of such drainage may influence the surgical management of patients...
  11. ncbi request reprint Variability of cutaneous lymphatic flow rates in melanoma patients
    R F Uren
    Missenden Medical Centre, Camperdown, NSW, Australia
    Melanoma Res 8:279-82. 1998
    ..These results can be used to optimize the timing of blue dye injection prior to surgery and may influence the sentinel node biopsy method to be used in individuals who show no early drainage...
  12. doi request reprint SPECT/CT scans allow precise anatomical location of sentinel lymph nodes in breast cancer and redefine lymphatic drainage from the breast to the axilla
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, Sydney, NSW, Australia
    Breast 21:480-6. 2012
    ..The purpose of this study was to confirm this is not correct...
  13. doi request reprint Internal mammary lymph node metastasis in breast cancer: predictive models to assist with prognostic influence
    F Noushi
    Department of Surgical Oncology, Mater and Royal North Shore Hospital, University of Sydney, Lindfield, NSW 2071, Sydney, Australia
    Breast 20:278-83. 2011
    ..1-6)..
  14. ncbi request reprint Single-dose isotope injection for both preoperative lymphoscintigraphy and intraoperative sentinel lymph node identification in melanoma patients
    J F Thompson
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Melanoma Res 7:500-6. 1997
    ....
  15. doi request reprint Internal mammary node metastasis in breast cancer: predictive models to determine status & management algorithms
    F Noushi
    Department of Surgical Oncology, Mater and Royal North Shore Hospital, University of Sydney, Sydney, Australia
    Eur J Surg Oncol 36:16-22. 2010
    ..Through mathematical modeling based on large datasets this study aims to estimate the current rate of IMN and sentinel node metastasis...
  16. ncbi request reprint Popliteal lymph node metastasis from primary cutaneous melanoma
    J F Thompson
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia
    Eur J Surg Oncol 26:172-6. 2000
    ..To document the incidence of popliteal lymph node involvement by metastatic melanoma and to consider the implications of this information for clinical management...
  17. ncbi request reprint Lymphatic mapping of the breast: locating the sentinel lymph nodes
    R F Uren
    Nuclear Medicine and Diagnostic Ultrasound, Suite 206, RPAH Medical Center, 100 Carillon Avenue, Newtown, N S W 2042, Australia
    World J Surg 25:789-93. 2001
    ..It is possible that in the future accurate nodal staging in each individual will involve biopsy of all sentinel lymph nodes, regardless of their location...
  18. ncbi request reprint Lymphatic mapping and sentinel node biopsy for melanoma
    J F Thompson
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Department of Surgery, University of Sydney, Sydney, New South Wales
    Expert Rev Anticancer Ther 1:446-52. 2001
    ..It is already clear, however, that SN examination provides very accurate staging, and SN biopsy is therefore essential for all melanoma patients entering adjuvant therapy trials...
  19. doi request reprint High-resolution lymphoscintigraphy is essential for recognition of the significance of internal mammary nodes in breast cancer
    A J Spillane
    Department of Surgical Oncology, The University of Sydney, Sydney, Australia
    Ann Oncol 20:977-84. 2009
    ..Controversy relates to the technique of lymphatic mapping, safety of IMN SNB, the significance of positive IMN, and potential to impact survival...
  20. ncbi request reprint Gallium and thallium scintigraphy in pediatric peripheral primitive neuroectodermal tumor (Askin tumor) of the chest wall
    R Howman Giles
    Department of Nuclear Medicine, Royal Alexandra Hospital for Children, Sydney, Australia
    J Nucl Med 36:814-6. 1995
    ..Histology showed a peripheral neuroectodermal tumor of the chest wall typical of the malignancy described as the Askin tumor. The 201Tl studies were a more accurate method of following tumor response to therapy than 67Ga scintigraphy...
  21. ncbi request reprint Surgical management of primary cutaneous melanoma: excision margins and the role of sentinel lymph node examination
    John F Thompson
    Sydney Melanoma Unit, Level 3, Gloucester House, Sydney Cancer Centre, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2006, Australia
    Surg Oncol Clin N Am 15:301-18. 2006
    ..Minimally invasive and noninvasive methods of SN assessment, such as magnetic resonance spectroscopy, are being evaluated...
  22. ncbi request reprint Neuroblastoma and other neuroendocrine tumors
    Robert Howman-Giles
    Department of Nuclear Medicine, Children s Hospital at Westmead, Sydney, NSW, Australia
    Semin Nucl Med 37:286-302. 2007
    ..Newer radiopharmaceuticals, including PET agents, are being evaluated for the assessment of NET. Nuclear medicine techniques play a major role in the management of neuroblastoma and NET...
  23. pmc Confirmation of sentinel lymph node identity by analysis of fine-needle biopsy samples using inductively coupled plasma-mass spectrometry
    Alison Beavis
    Department of Chemistry, Materials and Forensic Science, University of Technology, Sydney, New South Wales, Australia
    Ann Surg Oncol 15:934-40. 2008
    ..This involved the use of inductively coupled plasma-mass spectrometry (ICP-MS) to analyze antimony concentrations in fine-needle biopsy (FNB) samples from surgically procured lymph nodes...
  24. ncbi request reprint Mapping melanoma lymphoscintigraphy data onto a 3D anatomically based model
    Hayley M Reynolds
    The Bioengineering Institute, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Ann Biomed Eng 35:1444-57. 2007
    ..7% probability of dual drainage to both node fields, with 95% confidence limits between 14.5 and 21.0%...
  25. doi request reprint Management of merkel cell carcinoma: the roles of lymphoscintigraphy, sentinel lymph node biopsy and adjuvant radiotherapy
    Ross E Warner
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, 2050, Australia
    Ann Surg Oncol 15:2509-18. 2008
    ..However, its optimal treatment is uncertain. In this study, we aimed to assess the roles of lymphoscintigraphy and sentinel node (SN) biopsy, as well as radiotherapy, in the treatment of MCC...
  26. ncbi request reprint Three-dimensional visualisation of lymphatic drainage patterns in patients with cutaneous melanoma
    Hayley M Reynolds
    Bioengineering Institute, University of Auckland, Auckland, New Zealand
    Lancet Oncol 8:806-12. 2007
    ..We aimed to map these data onto a three-dimensional computer model to provide improved visualisation and analysis of lymphatic drainage from sites of cutaneous melanoma...
  27. doi request reprint False negative sentinel lymph node biopsies in melanoma may result from deficiencies in nuclear medicine, surgery, or pathology
    Rooshdiya Z Karim
    Department of Anatomical Pathology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Ann Surg 247:1003-10. 2008
    ..To investigate a cohort of melanoma patients with false negative (FN) sentinel node (SN) biopsies (SNBs) to identify the reasons for the FN result...
  28. ncbi request reprint Sentinel lymph node biopsy in melanoma
    Roger F Uren
    Discipline of Medicine University of Sydney Sydney, New South Wales Australia
    J Nucl Med 47:191-5. 2006
  29. ncbi request reprint Lymphatic mapping in management of patients with primary cutaneous melanoma
    John F Thompson
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Lancet Oncol 6:877-85. 2005
    ..Because it is impossible to predict the site or sites of sentinel nodes clinically in individual patients, routine preoperative lymphoscintigraphy is a prerequisite if reliable results are to be obtained from sentinel-node biopsy...
  30. ncbi request reprint Antimony by ICP-MS as a marker for sentinel lymph nodes in melanoma patients
    Michael Dawson
    Department of Chemistry, Materials and Forensic Science, University of Technology, Sydney, 1 Broadway, Broadway, NSW 2007, Australia
    Analyst 128:217-9. 2003
    ..A sensitive, accurate and specific method for the analysis of antimony by ICP-MS is presented as a marker of the sentinel lymph node in melanoma patients...
  31. ncbi request reprint Nuclear medicine aspects of melanoma and breast lymphatic mapping
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre, Camperdown, NSW, Australia
    Semin Oncol 31:338-48. 2004
    ..LS is an important first step to ensure this goal is achieved...
  32. ncbi request reprint Teaching points on lymphatic mapping for melanoma from the Sydney Melanoma Unit
    John F Thompson
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Semin Oncol 31:349-56. 2004
    ....
  33. ncbi request reprint Antimony concentrations in nodal tissue can confirm sentinel node identity
    Richard A Scolyer
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Mod Pathol 17:1191-7. 2004
    ....
  34. ncbi request reprint Failure to remove true sentinel nodes can cause failure of the sentinel node biopsy technique: evidence from antimony concentrations in false-negative sentinel nodes from melanoma patients
    Richard A Scolyer
    Sydney Melanoma Unit and Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, Australia
    Ann Surg Oncol 11:174S-8S. 2004
    ..Our results suggest that an FN SNB can occur because of failure to remove the true SN as well as histopathologic misdiagnosis...
  35. ncbi request reprint Sentinel node biopsy for melanoma: Where have we been and where are we going?
    John F Thompson
    Sydney Melanoma Unit and the Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, New South Wales, Australia
    Ann Surg Oncol 11:147S-51S. 2004
    ..Techniques such as in vivo proton magnetic resonance spectroscopy hold great promise and suggest that this goal might be achievable...
  36. ncbi request reprint Minimally invasive radio-guided surgery for recurrent thyroid cancer using iodine-123
    Robert Mansberg
    Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Clin Nucl Med 30:43-4. 2005
  37. ncbi request reprint Ultrasound examination of sentinel nodes in the initial assessment of patients with primary cutaneous melanoma
    Emma C Starritt
    Sydney Melanoma Unit, Sydney Cancer Centre and Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, 2050, Australia
    Ann Surg Oncol 12:18-23. 2005
    ..The aim of this study was to determine the threshold size of metastatic melanoma deposits in SLNs able to be detected by targeted US examination before initial melanoma surgery...
  38. ncbi request reprint Outcome in 846 cutaneous melanoma patients from a single center after a negative sentinel node biopsy
    Vivian S K Yee
    Sydney Melanoma Unit, Sydney Cancer Centre, Gloucester House, Royal Prince Alfred Hospital, Missenden Road, Camperdown, 2050 New South Wales, Australia
    Ann Surg Oncol 12:429-39. 2005
    ..A negative sentinel node biopsy (SNB) implies a good prognosis for melanoma patients. The purpose of this study was to determine the long-term outcome for melanoma patients with a negative SNB...
  39. ncbi request reprint Cancer surgery joins the dots
    Roger F Uren
    Nat Biotechnol 22:38-9. 2004
  40. ncbi request reprint A sentinel node biopsy does not increase the incidence of in-transit metastasis in patients with primary cutaneous melanoma
    Daan van Poll
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia
    Ann Surg Oncol 12:597-608. 2005
    ..It has been suggested that performing a sentinel node biopsy (SNB) in patients with cutaneous melanoma increases the incidence of in-transit metastasis (ITM)...
  41. ncbi request reprint Internal mammary node metastasis from primary cutaneous melanoma on the anterior chest
    John F Thompson
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    ANZ J Surg 75:723-5. 2005
    ..Direct lymphatic drainage from the skin of the anterior chest and breast to internal mammary lymph nodes does not normally occur...
  42. ncbi request reprint Role of lymphoscintigraphy for selective sentinel lymphadenectomy
    Roger F Uren
    Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre and Discipline of Medicine, The University of Sydney, Sydney, NSW, Australia
    Cancer Treat Res 127:15-38. 2005
    ..LS is an important first step in ensuring that this goal is achieved...
  43. pmc Correlation between preoperative lymphoscintigraphy and metastatic nodal disease sites in 362 patients with cutaneous melanomas of the head and neck
    Johannes H W de Wilt
    Sydney Melanoma Unit and the Melanoma and Skin Cancer Research Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, New South Wales, Australia
    Ann Surg 239:544-52. 2004
    ..To assess the clinical relevance of these discordant node fields, the lymphoscintigrams of patients with head and neck melanomas were analyzed and correlated with the sites of metastatic nodal disease...
  44. pmc Diagnostic accuracy of fine needle biopsy for metastatic melanoma and its implications for patient management
    Anna Doubrovsky
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia
    Ann Surg Oncol 15:323-32. 2008
    ..In this study, the accuracy of FNB for the diagnosis of metastatic melanoma was investigated...
  45. ncbi request reprint Left-to-right cardiac shunt diagnosed on Tc-99m MAG-3 renal study
    Hamda Saleh
    Department of Nuclear Medicine, The Children s Hospital at Westmead, UK
    Clin Nucl Med 29:762-4. 2004
  46. ncbi request reprint Diagnosis of metastatic melanoma by fine-needle biopsy: analysis of 2,204 cases
    Rajmohan Murali
    Department of Anatomical Pathology, Sydney Cancer Centre, Australia
    Am J Clin Pathol 127:385-97. 2007
    ..FNB is a highly accurate, rapid, and cost-effective procedure for the diagnosis of metastatic melanoma and should be considered as the initial diagnostic procedure of choice in patients with melanoma with clinically suspected metastases...
  47. ncbi request reprint Selective sentinel lymphadenectomy: progress to date and prospects for the future
    John F Thompson
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia
    Cancer Treat Res 127:269-87. 2005
    ....