Paul A Tooney

Summary

Affiliation: University of Newcastle
Country: Australia

Publications

  1. ncbi Gene expression profiling of xeroderma pigmentosum
    Nikola A Bowden
    Hunter Medical Research Institute, John Hunter Hospital, Lookout Rd, New Lambton Heights, NSW, 2305, Australia
    Hered Cancer Clin Pract 4:103-10. 2006
  2. ncbi Tachykinin NK1 and NK3 receptors in the prefrontal cortex of the human brain
    P A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders and School of Biomedical Sciences, Faculty of Medicine and Health Sciences, The University of Newcastle, Callaghan, New South Wales, Australia
    Clin Exp Pharmacol Physiol 27:947-9. 2000
  3. ncbi Neurons expressing calcium-binding proteins in the prefrontal cortex in schizophrenia
    Paul A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders, Darlinghurst, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 28:273-8. 2004
  4. ncbi The effects of haloperidol treatment on the distribution of NK1 receptor immunoreactive neurons in guinea-pig brain
    Paul A Tooney
    NISAD, Neuroscience Institute of Schizophrenia and Allied Disorders NISAD, Sydney, Australia
    Neurosci Lett 383:155-9. 2005
  5. ncbi Transcriptome sequencing revealed significant alteration of cortical promoter usage and splicing in schizophrenia
    Jing Qin Wu
    Schizophrenia Research Institute, Sydney, Australia
    PLoS ONE 7:e36351. 2012
  6. ncbi Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia
    Danielle M Santarelli
    Schizophrenia Research Institute, Sydney, Australia
    Biol Psychiatry 69:180-7. 2011
  7. ncbi Immunohistochemical localisation of the NK1 receptor in the human amygdala: preliminary investigation in schizophrenia
    Judith Weidenhofer
    Neuroscience Institute of Schizophrenia and Allied Disorders, Sydney, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 30:1313-21. 2006
  8. ncbi Down-regulation of miR-17 family expression in response to retinoic acid induced neuronal differentiation
    Natalie J Beveridge
    Schizophrenia Research Institute, Sydney, NSW 2006, Australia
    Cell Signal 21:1837-45. 2009
  9. ncbi Altered gene expression in the superior temporal gyrus in schizophrenia
    Nikola A Bowden
    Neuroscience Institute of Schizophrenia and Allied Disorders, Sydney, NSW, Australia
    BMC Genomics 9:199. 2008
  10. ncbi Dysregulation of miRNA 181b in the temporal cortex in schizophrenia
    Natalie J Beveridge
    Schizophrenia Research Institute, Sydney, NSW 2006, Australia
    Hum Mol Genet 17:1156-68. 2008

Detail Information

Publications16

  1. ncbi Gene expression profiling of xeroderma pigmentosum
    Nikola A Bowden
    Hunter Medical Research Institute, John Hunter Hospital, Lookout Rd, New Lambton Heights, NSW, 2305, Australia
    Hered Cancer Clin Pract 4:103-10. 2006
    ..Therefore, this analysis has revealed distinct gene expression profiles for the XP complementation groups and the first step towards understanding the neurological symptoms of XP...
  2. ncbi Tachykinin NK1 and NK3 receptors in the prefrontal cortex of the human brain
    P A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders and School of Biomedical Sciences, Faculty of Medicine and Health Sciences, The University of Newcastle, Callaghan, New South Wales, Australia
    Clin Exp Pharmacol Physiol 27:947-9. 2000
    ..Dots of NK3 receptor immunoreactivity were scattered across all cortical layers. In the white matter, astrocytes and beaded fibres displayed NK3 receptor immunoreactivity, particularly in areas surrounding blood vessels...
  3. ncbi Neurons expressing calcium-binding proteins in the prefrontal cortex in schizophrenia
    Paul A Tooney
    Neuroscience Institute of Schizophrenia and Allied Disorders, Darlinghurst, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 28:273-8. 2004
    ....
  4. ncbi The effects of haloperidol treatment on the distribution of NK1 receptor immunoreactive neurons in guinea-pig brain
    Paul A Tooney
    NISAD, Neuroscience Institute of Schizophrenia and Allied Disorders NISAD, Sydney, Australia
    Neurosci Lett 383:155-9. 2005
    ..Whether these changes are related to the therapeutic effects or to the side effects of haloperidol in individuals with schizophrenia, remains to be determined...
  5. ncbi Transcriptome sequencing revealed significant alteration of cortical promoter usage and splicing in schizophrenia
    Jing Qin Wu
    Schizophrenia Research Institute, Sydney, Australia
    PLoS ONE 7:e36351. 2012
    ..By contrast, sequencing technology can provide un-biased analysis of transcription at nucleotide resolution. Here we use this approach to investigate schizophrenia-associated cortical gene expression...
  6. ncbi Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia
    Danielle M Santarelli
    Schizophrenia Research Institute, Sydney, Australia
    Biol Psychiatry 69:180-7. 2011
    ..We hypothesize that abnormal miRNA levels contribute to the complex global changes in gene expression that underlie the pathophysiology of schizophrenia...
  7. ncbi Immunohistochemical localisation of the NK1 receptor in the human amygdala: preliminary investigation in schizophrenia
    Judith Weidenhofer
    Neuroscience Institute of Schizophrenia and Allied Disorders, Sydney, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 30:1313-21. 2006
    ....
  8. ncbi Down-regulation of miR-17 family expression in response to retinoic acid induced neuronal differentiation
    Natalie J Beveridge
    Schizophrenia Research Institute, Sydney, NSW 2006, Australia
    Cell Signal 21:1837-45. 2009
    ..This suggests that the miR-17 family have an integral role in fine-tuning the pathways involved in the regulation of neuronal differentiation...
  9. ncbi Altered gene expression in the superior temporal gyrus in schizophrenia
    Nikola A Bowden
    Neuroscience Institute of Schizophrenia and Allied Disorders, Sydney, NSW, Australia
    BMC Genomics 9:199. 2008
    ..The STG connects to the limbic system (hippocampus and amygdala), the thalamus and neocortical association areas in the prefrontal cortex, all of which have been implicated in schizophrenia...
  10. ncbi Dysregulation of miRNA 181b in the temporal cortex in schizophrenia
    Natalie J Beveridge
    Schizophrenia Research Institute, Sydney, NSW 2006, Australia
    Hum Mol Genet 17:1156-68. 2008
    ..This study suggests altered miRNA levels could be a significant factor in the dysregulation of cortical gene expression in schizophrenia...
  11. ncbi Preliminary investigation of gene expression profiles in peripheral blood lymphocytes in schizophrenia
    Nikola A Bowden
    Neuroscience Institute of Schizophrenia and Allied Disorders, Australia
    Schizophr Res 82:175-83. 2006
    ..The validity of this approach may lead to better methods of defining this enigmatic disease...
  12. ncbi Finding the needle in the haystack: a review of microarray gene expression research into schizophrenia
    Nishantha Kumarasinghe
    Priority Centre for Translational Neuroscience and Mental Health Research, University of Newcastle, Callaghan, Australia
    Aust N Z J Psychiatry 46:598-610. 2012
    ..Hence, the expression of susceptibility genes in response to environmental factors in concert with other disease-promoting or protecting genes has increasingly attracted attention...
  13. ncbi Alternative mRNA fates identified in microRNA-associated transcriptome analysis
    Adam P Carroll
    School of Biomedical Sciences and Pharmacy, Faculty of Health and Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW, Australia
    BMC Genomics 13:561. 2012
    ....
  14. ncbi Different forms of glycine- and GABA(A)-receptor mediated inhibitory synaptic transmission in mouse superficial and deep dorsal horn neurons
    Wayne B Anderson
    School of Biomedical Sciences and Pharmacy, The University of Newcastle and Hunter Medical Research Institute, University Drive, Callaghan, NSW 2308, Australia
    Mol Pain 5:65. 2009
    ..Recent work in mouse has discovered an additional type of GlyR, (containing alpha 3 subunits) in the SDH. The contribution of differing forms of the GlyR to sensory processing in SDH and DDH is not understood...
  15. ncbi Altered expression of regulator of G-protein signalling 4 (RGS4) mRNA in the superior temporal gyrus in schizophrenia
    Nikola A Bowden
    Neuroscience Institute of Schizophrenia and Allied Disorders, Sydney, Australia
    Schizophr Res 89:165-8. 2007
    ..Altered expression of RGS4 in cortical regions previously implicated in schizophrenia, such as the STG further supports the notion of RGS4 as a potential genetic and functional biological marker of schizophrenia...
  16. ncbi Altered gene expression in the amygdala in schizophrenia: up-regulation of genes located in the cytomatrix active zone
    Judith Weidenhofer
    Neuroscience Institute of Schizophrenia and Allied Disorders (NISAD, NSW, Australia
    Mol Cell Neurosci 31:243-50. 2006
    ..These results implicate for the first time the dysfunction of the cytomatrix active zone of synapses in the amygdala in the pathophysiology of schizophrenia...