M Stowasser

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. ncbi Hyperaldosteronism: primary versus tertiary
    Michael Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Brisbane 4102, Australia
    J Hypertens 20:17-9. 2002
  2. ncbi Biochemical evidence of aldosterone overproduction and abnormal regulation in normotensive individuals with familial hyperaldosteronism type I
    M Stowasser
    University Department of Medicine, Greenslopes Hospital, Brisbane, Australia
    J Clin Endocrinol Metab 84:4031-6. 1999
  3. ncbi Familial varieties of primary aldosteronism
    M Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Queensland, Australia
    Clin Exp Pharmacol Physiol 28:1087-90. 2001
  4. ncbi Familial hyperaldosteronism
    M Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, QLD 4120, Brisbane, Australia
    J Steroid Biochem Mol Biol 78:215-29. 2001
  5. ncbi New perspectives on the role of aldosterone excess in cardiovascular disease
    M Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    Clin Exp Pharmacol Physiol 28:783-91. 2001
  6. ncbi Primary aldosteronism: rare bird or common cause of secondary hypertension?
    M Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane 4102, Australia
    Curr Hypertens Rep 3:230-9. 2001
  7. ncbi Primary aldosteronism: learning from the study of familial varieties
    M Stowasser
    University Department of Medicine, Greenslopes Hospital, Brisbane, Australia
    J Hypertens 18:1165-76. 2000
  8. ncbi Primary aldosteronism: from genesis to genetics
    Michael Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Brisbane 4102, Australia
    Trends Endocrinol Metab 14:310-7. 2003
  9. ncbi Factors affecting the aldosterone/renin ratio
    M Stowasser
    Endocrine Hypertension Research Centre, University of Queensland School of Medicine, Greenslopes and Princess Alexandra Hospitals, Brisbane, Australia
    Horm Metab Res 44:170-6. 2012
  10. ncbi Unilateral adrenalectomy improves urinary protein excretion but does not abolish its relationship to sodium excretion in patients with aldosterone-producing adenoma
    E Pimenta
    Endocrine Hypertension Research Centre, University of Queensland School of Medicine, Princess Alexandra and Greenslopes Hospitals, Brisbane, Queensland, Australia
    J Hum Hypertens 25:592-9. 2011

Collaborators

Detail Information

Publications36

  1. ncbi Hyperaldosteronism: primary versus tertiary
    Michael Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Brisbane 4102, Australia
    J Hypertens 20:17-9. 2002
  2. ncbi Biochemical evidence of aldosterone overproduction and abnormal regulation in normotensive individuals with familial hyperaldosteronism type I
    M Stowasser
    University Department of Medicine, Greenslopes Hospital, Brisbane, Australia
    J Clin Endocrinol Metab 84:4031-6. 1999
    ..The absence of hypertension in such individuals, therefore, cannot be attributed to lack of biochemical expression of the hybrid gene...
  3. ncbi Familial varieties of primary aldosteronism
    M Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Queensland, Australia
    Clin Exp Pharmacol Physiol 28:1087-90. 2001
    ..As has already occurred in FH-I, elucidation of causative mutations is likely to facilitate earlier detection of PAL...
  4. ncbi Familial hyperaldosteronism
    M Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, QLD 4120, Brisbane, Australia
    J Steroid Biochem Mol Biol 78:215-29. 2001
    ..As has already occurred in FH-I, elucidation of causative mutations is likely to facilitate earlier detection of PAL and other curable or specifically treatable forms of hypertension...
  5. ncbi New perspectives on the role of aldosterone excess in cardiovascular disease
    M Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    Clin Exp Pharmacol Physiol 28:783-91. 2001
    ....
  6. ncbi Primary aldosteronism: rare bird or common cause of secondary hypertension?
    M Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane 4102, Australia
    Curr Hypertens Rep 3:230-9. 2001
    ....
  7. ncbi Primary aldosteronism: learning from the study of familial varieties
    M Stowasser
    University Department of Medicine, Greenslopes Hospital, Brisbane, Australia
    J Hypertens 18:1165-76. 2000
    ....
  8. ncbi Primary aldosteronism: from genesis to genetics
    Michael Stowasser
    Hypertension Unit, University Department of Medicine, Princess Alexandra Hospital, Brisbane 4102, Australia
    Trends Endocrinol Metab 14:310-7. 2003
  9. ncbi Factors affecting the aldosterone/renin ratio
    M Stowasser
    Endocrine Hypertension Research Centre, University of Queensland School of Medicine, Greenslopes and Princess Alexandra Hospitals, Brisbane, Australia
    Horm Metab Res 44:170-6. 2012
    ..Liquid chromatography-tandem mass spectrometry aldosterone assays represent a major advance towards addressing inaccuracies inherent in other available methods...
  10. ncbi Unilateral adrenalectomy improves urinary protein excretion but does not abolish its relationship to sodium excretion in patients with aldosterone-producing adenoma
    E Pimenta
    Endocrine Hypertension Research Centre, University of Queensland School of Medicine, Princess Alexandra and Greenslopes Hospitals, Brisbane, Queensland, Australia
    J Hum Hypertens 25:592-9. 2011
    ....
  11. ncbi Primary aldosteronism: are we diagnosing and operating on too few patients?
    R D Gordon
    Endocrine Hypertension Research Unit, University of Queensland, Department of Medicine, Greenslopes Hospital, Brisbane 4120, Australia
    World J Surg 25:941-7. 2001
    ....
  12. ncbi Central blood pressure measurement may improve risk stratification
    Je Sharman
    Department of Medicine, Princess Alexandra Hospital, University of Queensland, Brisbane, Queensland, Australia
    J Hum Hypertens 22:838-44. 2008
    ..This results in a significant overlap of central SBP scores between brachial SBP risk groups. This is likely to have treatment implications but remains to be tested...
  13. ncbi Arterial stiffness, central blood pressure and body size in health and disease
    O O Kolade
    The University of Queensland, School of Human Movement Studies, Brisbane, Queensland, Australia
    Int J Obes (Lond) 36:93-9. 2012
    ..We also sought to determine if aortic stiffness was correlated with body size, independent of BP...
  14. ncbi Salt, aldosterone and hypertension
    E Pimenta
    Endocrine Hypertension Research Centre, University of Queensland School of Medicine, Princess Alexandra and Greenslopes Hospitals, Brisbane, Queensland, Australia
    J Hum Hypertens 27:1-6. 2013
    ..Furthermore, aldosterone reduction or blockade may reduce salt appetite...
  15. ncbi Examination of chromosome 7p22 candidate genes RBaK, PMS2 and GNA12 in familial hyperaldosteronism type II
    Y W A Jeske
    Endocrine Hypertension Research Centre, University of Queensland School of Medicine, Greenslopes Hospital, Brisbane, Queensland, Australia
    Clin Exp Pharmacol Physiol 35:380-5. 2008
    ..Although present in the normal population, it is possible that the RBaK (-)2031T/2030G/834C/821T and PMS2 (-)876G alleles may have functional roles contributing to the FH-II phenotype in family 1...
  16. ncbi Polymorphisms of the renin-angiotensin system in patients with multifocal renal arterial fibromuscular dysplasia
    A Bofinger
    Hypertension Unit, University of Queensland Department of Medicine, Greenslopes Private Hospital, Brisbane, Queensland, Australia
    J Hum Hypertens 15:185-90. 2001
    ..This contrasts with atherosclerotic renal artery stenosis, coronary stent restenosis and carotid intimal thickening, which are diseases affecting the arterial intima, and which are associated with increased frequency of the D allele...
  17. ncbi Are thiazide diuretics preferred as first-line therapy for hypertension? An appraisal of The Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    I Scott
    Department of Internal Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    Intern Med J 33:327-30. 2003
  18. ncbi High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients
    Michael Stowasser
    Hypertension Unit, University of Queensland Department of Medicine, Princess Alexandra Hospital, Brisbane, Australia
    J Hypertens 21:2149-57. 2003
    ..Some investigators, however, have reported aldosterone-producing adenoma to be rare among patients so detected...
  19. ncbi The aldosterone-renin ratio and primary aldosteronism
    Michael Stowasser
    Mayo Clin Proc 77:202-3. 2002
  20. ncbi Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline
    John W Funder
    Prince Henry s Institute of Medical Research, Clayton, Vic, Australia
    J Clin Endocrinol Metab 93:3266-81. 2008
    ..Our objective was to develop clinical practice guidelines for the diagnosis and treatment of patients with primary aldosteronism...
  21. ncbi Primary aldosteronism: the case for screening
    Richard D Gordon
    Endocrine Hypertension Research Centre, University of Queensland School of Medicine, Princess Alexandra Hospital, Brisbane, Australia
    Nat Clin Pract Nephrol 3:582-3. 2007
  22. ncbi Aldosterone excess, hypertension, and chromosome 7p22: evidence continues to mount
    Michael Stowasser
    Hypertension 49:761-2. 2007
  23. ncbi Effect of aldosterone antagonism on myocardial dysfunction in hypertensive patients with diastolic heart failure
    Philip M Mottram
    University of Queensland, Brisbane, Australia
    Circulation 110:558-65. 2004
    ..The spironolactone group also exhibited reduction in posterior wall thickness (P=0.04) and a trend to reduced left atrial area (P=0.09). CONCLUSIONS: Aldosterone antagonism improves myocardial function in hypertensive heart disease...
  24. ncbi Aldosterone assays: an urgent need for improvement
    Michael Stowasser
    Clin Chem 52:1640-2. 2006
  25. ncbi Primary aldosteronism--careful investigation is essential and rewarding
    Michael Stowasser
    Hypertension Unit, University of Queensland, Department of Medicine, Princvess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane 4102, Australia
    Mol Cell Endocrinol 217:33-9. 2004
    ..Genetic testing has facilitated detection of glucocorticoid-remediable, familial PAL. Identification of mutations causing the more common familial variety described by GHHU in 1991 should further aid in detection of PAL...
  26. ncbi Familial hyperaldosteronism type II is linked to the chromosome 7p22 region but also shows predicted heterogeneity
    Albertina So
    Endocrine Hypertension Research Centre, University of Queensland, Princess Alexandra Hospital, Brisbane, Australia
    J Hypertens 23:1477-84. 2005
    ..Mutations in the exons or intron-exon boundaries of PRKAR1B (7p22, closely related to PRKAR1A, which is mutated in Carney complex) have been excluded in this family...
  27. ncbi Evidence for abnormal left ventricular structure and function in normotensive individuals with familial hyperaldosteronism type I
    Michael Stowasser
    Hypertension Unit, University of Queensland Department of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, Queensland 4102, Australia
    J Clin Endocrinol Metab 90:5070-6. 2005
    ....
  28. ncbi Left ventricular mass in patients with type 2 diabetes is independently associated with central but not peripheral pulse pressure
    James E Sharman
    University of Queensland, Department of Medicine, Princess Alexandra Hospital, Ipswich Road, Brisbane, Queensland 4102, Australia
    Diabetes Care 28:937-9. 2005
  29. ncbi Primary aldosteronism
    Michael Stowasser
    Hypertension Unit, University of Queensland Department of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane 4102, Australia
    Best Pract Res Clin Endocrinol Metab 17:591-605. 2003
    ....
  30. ncbi Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents
    Paolo Mulatero
    Hypertension Unit, Department of Medicine and Experimental Oncology, University of Torino, 10133 Turin, Italy
    J Clin Endocrinol Metab 89:1045-50. 2004
    ..In conclusion, the wide use of the ARR as a screening test in hypertensive patients led to a marked increase in the detection rate of PA...
  31. ncbi Haplotype analysis of aldosterone synthase gene (CYP11B2) polymorphisms shows association with essential hypertension
    Natasha N Kumar
    Department of Physiology, School of Medical Sciences, and Institute for Biomedical Research, The University of Sydney, Sydney, Australia
    J Hypertens 21:1331-7. 2003
    ..We therefore investigated CYP11B2 polymorphisms T-344C, T4986C and A6547G for association with essential HT. This included haplotype analysis and measurement of plasma aldosterone levels...
  32. ncbi Further evidence for linkage of familial hyperaldosteronism type II at chromosome 7p22 in Italian as well as Australian and South American families
    Norlela Sukor
    Endocrine Hypertension Research Center, University of Queensland School of Medicine, Greenslopes Hospital, Brisbane, Australia
    J Hypertens 26:1577-82. 2008
    ....
  33. ncbi Monogenic mineralocorticoid hypertension
    Michael Stowasser
    Endocrine Hypertension Research Centre, University of Queensland School of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, Australia 4102
    Best Pract Res Clin Endocrinol Metab 20:401-20. 2006
    ....
  34. ncbi Cochrane and the salt debate
    Trevor C Beard
    Lancet 362:403; discussion 403. 2003
  35. ncbi Genomic structure of the human gene for protein kinase A regulatory subunit R1-beta (PRKAR1B) on 7p22: no evidence for mutations in familial hyperaldosteronism type II in a large affected kindred
    Martin S Elphinstone
    Hypertension Units, University of Queensland Department of Medicine, Princess Alexandra and Greenslopes Hospitals, Brisbane 4102, Australia
    Clin Endocrinol (Oxf) 61:716-23. 2004
    ..Alternatively, a mutation within another gene residing at the 7p22 locus may be responsible...
  36. ncbi No evidence for coding region mutations in the retinoblastoma-associated Kruppel-associated box protein gene (RBaK) causing familial hyperaldosteronism type II
    Albertina So
    Clin Endocrinol (Oxf) 65:829-31. 2006