Kirsten M Spann

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. Spann K, Loh Z, Lynch J, Ullah A, Zhang V, Baturcam E, et al. IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice. Am J Pathol. 2014;184:1795-806 pubmed publisher
    ..In the absence of a robust type I IFN-?/? response, targeting the IPS-1 signaling pathway may limit the overexuberant inflammatory response that occurs as a consequence of viral persistence. ..
  2. Lin M, Sivakumaran H, Jones A, Li D, Harper C, Wei T, et al. A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1. Retrovirology. 2014;11:121 pubmed publisher
    ..Furthermore, our research raises the possibility that wild type Tat may play a previously unrecognized but very important role in Rev function. ..