Kirsten M Spann

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. ncbi request reprint IRF-3, IRF-7, and IPS-1 Promote Host Defense against Acute Human Metapneumovirus Infection in Neonatal Mice
    Kirsten M Spann
    Clinical Medical Virology Centre, University of Queensland, St Lucia, Australia Sir Albert Sakzewski Virus Research Centre, Children s Hospital Queensland, Australia Australian Infectious Diseases Research Centre, University of Queensland, St Lucia, Australia Electronic address
    Am J Pathol 184:1795-806. 2014
  2. pmc siRNA against the G gene of human metapneumovirus
    Faith Maxine Preston
    Clinical Medical Virology Centre, The University of Queensland, Brisbane, QLD 4072, Australia
    Virol J 9:105. 2012
  3. pmc Mutation of the elongin C binding domain of human respiratory syncytial virus non-structural protein 1 (NS1) results in degradation of NS1 and attenuation of the virus
    Claire P Straub
    The University of Queensland, Clinical Medical Virology Centre, QLD 4072, Australia
    Virol J 8:252. 2011

Collaborators

  • Claire P Straub
  • Faith Maxine Preston
  • Suresh Mahalingam
  • Ruben Ramirez
  • Peter L Collins
  • Faith M Preston
  • Wei Har Lau
  • Madeleine J Headlam
  • Jeffery J Gorman

Detail Information

Publications3

  1. ncbi request reprint IRF-3, IRF-7, and IPS-1 Promote Host Defense against Acute Human Metapneumovirus Infection in Neonatal Mice
    Kirsten M Spann
    Clinical Medical Virology Centre, University of Queensland, St Lucia, Australia Sir Albert Sakzewski Virus Research Centre, Children s Hospital Queensland, Australia Australian Infectious Diseases Research Centre, University of Queensland, St Lucia, Australia Electronic address
    Am J Pathol 184:1795-806. 2014
    ..In the absence of a robust type I IFN-α/β response, targeting the IPS-1 signaling pathway may limit the overexuberant inflammatory response that occurs as a consequence of viral persistence. ..
  2. pmc siRNA against the G gene of human metapneumovirus
    Faith Maxine Preston
    Clinical Medical Virology Centre, The University of Queensland, Brisbane, QLD 4072, Australia
    Virol J 9:105. 2012
    ..The glycosylated G attachment protein of hMPV is required for viral entry in vivo and has also been identified as an inhibitor of innate immune responses...
  3. pmc Mutation of the elongin C binding domain of human respiratory syncytial virus non-structural protein 1 (NS1) results in degradation of NS1 and attenuation of the virus
    Claire P Straub
    The University of Queensland, Clinical Medical Virology Centre, QLD 4072, Australia
    Virol J 8:252. 2011
    ..It has been proposed that NS1 binds to elongin C to form a ubiquitin ligase (E3) complex that targets STAT2 for ubiquitination and proteosomal degradation...