Peter D Sly
Affiliation: University of Queensland
- The early origins of asthma: who is really at risk?Peter D Sly
Deputy Director, Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Australia
Curr Opin Allergy Clin Immunol 11:24-8. 2011..This review will comment on the latest evidence in this field...
- Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung diseaseEmmanuelle Fantino
The Queensland Children s Medical Research Institute, The University of Queensland, Level 4, Foundation Building, Royal Children s Hospital, Herston Road, Herston, Brisbane, QLD 4059, Australia
BMC Pulm Med 14:28. 2014..The chitinase-like protein YKL-40 is raised in sputum and serum of adults with CF. We investigated YKL-40 in BAL, serum and urine to determine whether this reflected inflammation and infection in young children with CF...
- In utero exposure to low dose arsenic via drinking water impairs early life lung mechanics in miceKathryn A Ramsey
Division of Clinical Sciences, Telethon Institute for Child Health Research, 100 Roberts Road, Subiaco, WA, 6008, Australia
BMC Pharmacol Toxicol 14:13. 2013..The aim of this study was to determine if in utero exposure to low dose arsenic via drinking water is capable of altering lung growth and postnatal lung mechanics...
- Risk factors for bronchiectasis in children with cystic fibrosisPeter D Sly
Queensland Children s Medical Research Institute, Brisbane, Australia
N Engl J Med 368:1963-70. 2013..We sought to determine risk factors for the onset of bronchiectasis, using data collected by the Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF) intensive surveillance program...
- Medical research results in the general media: worthwhile and rewarding if presented well, potentially harmful if prepared poorlyPeter D Sly
Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Australia
Paediatr Respir Rev 12:277-80. 2011....
- Health impacts of climate change and biosecurity in the Asian Pacific regionPeter D Sly
Queensland Children s Medical Research Institute, University of Queensland, Royal Children s Hospital, Herston, Brisbane, Australia
Rev Environ Health 26:7-12. 2011..Strategies addressing the health impacts of climate change must incorporate the principles of social justice and equity within the region...
- Role of innate immunity in the development of allergy and asthmaPeter D Sly
Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia
Curr Opin Allergy Clin Immunol 11:127-31. 2011..The purpose of this review is to examine the role of innate immunity in the lungs in the development of allergy and asthma...
- Using mathematical transmission modelling to investigate drivers of respiratory syncytial virus seasonality in children in the PhilippinesStuart Paynter
School of Population Health, University of Queensland, Brisbane, Queensland, Australia
PLoS ONE 9:e90094. 2014..The timing of the seasonal patterns of nutritional status and rainfall were both consistent with the estimated seasonal pattern of transmissibility and these are both plausible drivers of the seasonality of RSV in this setting. ..
- Reference ranges for Mexican preschool-aged children using the forced oscillation techniqueClaire Shackleton
Queensland Children s Medical Research Institute, The University of Queensland, Brisbane, Australia
Arch Bronconeumol 49:326-9. 2013..We aimed to develop FOT reference ranges for preschool-aged Mexican children and to compare these with current FOT reference ranges...
- Malnutrition: a risk factor for severe respiratory syncytial virus infection and hospitalizationStuart Paynter
From the School of Population Health Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Australia Research Institute of Tropical Medicine, Manila, the Philippines Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland Barbara Hardy Institute, University of South Australia, Adelaide, Australia University of Colorado Denver, School of Medicine Center for Global Health, Colorado School of Public Health and Children s Hospital Colorado, Aurora, CO
Pediatr Infect Dis J 33:267-71. 2014..Children hospitalized with RSV lower respiratory infection represent those at the severe end of the disease spectrum...
- The impact of birth weight on peak lung function in young adultsSadasivam Suresh
School of Population Health, University of Queensland, Brisbane, QLD, Australia
Chest 142:1603-10. 2012..A birth cohort provides the opportunity to study the association between birth weight and adult respiratory function...
- Providing feedback on adherence increases use of preventive medication by asthmatic childrenScott W Burgess
Department of Paediatrics, Redland Hospital, Brisbane, Queensland, 4163 Australia
J Asthma 47:198-201. 2010..Measuring adherence and providing feedback increases the use of preventive medication. A larger study is required to explore implications for disease control...
- Relationship between environmental exposures in children and adult lung disease: the case for outdoor exposuresManuel Soto-Martinez
Department of Respiratory Medicine, Royal Children s Hospital, Australia
Chron Respir Dis 7:173-86. 2010..An understanding of how ambient exposures impact on normal lung growth and development will aid in understanding of how chronic respiratory diseases of adults develop and may lead to new preventative strategies...
- Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezingJohn W Upham
Telethon Institute for Child Health Research, West Perth, and Centre for Child Health Research, University of Western Australia, Perth, Australia
J Allergy Clin Immunol 124:707-13.e2. 2009..However, it is not known specifically whether changes in dendritic cells (DCs) during infancy antedate the development of respiratory tract infections, asthma, and related clinical phenotypes...
- Poor growth and pneumonia seasonality in infants in the Philippines: cohort and time series studiesStuart Paynter
School of Population Health, University of Queensland, Brisbane, Queensland, Australia
PLoS ONE 8:e67528. 2013..Further investigation of the seasonal level association, in particular the estimation of the expected lag between seasonal undernutrition and increased pneumonia incidence, is recommended. ..
- Environmental exposures: an underrecognized contribution to noncommunicable diseasesRosana E Norman
Children s Halth and Environment Program, Queenland Children s Medical Research Institute, The University of Queenland, Herston, Australia
Rev Environ Health 28:59-65. 2013....
- Respiratory viral infections in children with asthma: do they matter and can we prevent them?Hamid Ahanchian
The Queensland Children s Medical Research Institute, The University of Queensland, Brisbane, Australia
BMC Pediatr 12:147. 2012..Acute exacerbations are associated with decreased lung growth or accelerated loss of lung function and, as such, add substantially to both the cost and morbidity associated with asthma...
- Factors influencing the assessment of lung function in mice with influenza-induced lung diseaseAlexander N Larcombe
Division of Clinical Sciences, Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth, WA, Australia Airway Physiology Imaging Research Group, Woolcock Institute of Medical Research, Sydney, NSW, Australia Department of Medical Physics and Informatics, University of Szeged, Szeged, Hungary Queensland Children s Medical Research Institute, University of Queensland, Brisbane, QLD, Australia
Influenza Other Respir Viruses 7:889-94. 2013..Driving signal frequencies and the method of model fitting may influence the results, especially in cases of severe lung disease or under severe bronchoconstriction...
- Adolescent peer aggression and its association with mental health and substance use in an Australian cohortSophie E Moore
Children s Health and Environment Program, Queensland Children s Medical Research Institute, University of Queensland, Royal Children s Hospital, Herston, QLD, 4029, Australia
J Adolesc 37:11-21. 2014..These results show an independent temporal relationship between peer aggression and later mental health and substance use problems in adolescence. ..
- Clarithromycin therapy for patients with cystic fibrosis: a randomized controlled trialP Robinson
Department of Respiratory Medicine, Royal Children s Hospital, Murdoch Children s Research Instutite, Australia
Pediatr Pulmonol 47:551-7. 2012..We conclude that clarithromycin is not effective in treating CF lung disease...
- Lung function, bronchial responsiveness, and asthma in a community cohort of 6-year-old childrenJacqui Joseph-Bowen
Division of Clinical Sciences, Biostatiscs and Genetic Epidemiology, Population Sciences and Cell Biology, Telethon Institute for Child Health Research, University of Western, Australia, Perth, Australia
Am J Respir Crit Care Med 169:850-4. 2004..Lung function testing, including methacholine challenge, is feasible in 5- to 7-year-old children and has the potential to contribute to the clinical management of children with asthma.Keywords:..
- Identification of IL6R and chromosome 11q13.5 as risk loci for asthmaManuel A R Ferreira
The Queensland Institute of Medical Research, Brisbane, QLD, Australia
Lancet 378:1006-14. 2011..We aimed to identify novel genetic variants affecting asthma risk, since these might provide novel insights into molecular mechanisms underlying the disease...
- Incentive device improves spacer technique but not clinical outcome in preschool children with asthmaAndré Schultz
School of Paediatrics and Child Health, University of Western, Perth, Western Australia, Australia
J Paediatr Child Health 48:52-6. 2012..To investigate the influence of an incentive device, the Funhaler, on spacer technique and symptom control in young children with asthma and recurrent wheeze...
- Assessing adherence and factors associated with adherence in young children with asthmaScott W Burgess
Department of Paediatrics, Redland Hospital, Cleveland, Queensland, Australia
Respirology 13:559-63. 2008..However, few data exist regarding the accuracy of subjective measures of adherence and factors associated with adherence in young children...