Peter D Sly

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. doi request reprint The early origins of asthma: who is really at risk?
    Peter D Sly
    Deputy Director, Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Australia
    Curr Opin Allergy Clin Immunol 11:24-8. 2011
  2. pmc Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung disease
    Emmanuelle Fantino
    The Queensland Children s Medical Research Institute, The University of Queensland, Level 4, Foundation Building, Royal Children s Hospital, Herston Road, Herston, Brisbane, QLD 4059, Australia
    BMC Pulm Med 14:28. 2014
  3. pmc In utero exposure to low dose arsenic via drinking water impairs early life lung mechanics in mice
    Kathryn A Ramsey
    Division of Clinical Sciences, Telethon Institute for Child Health Research, 100 Roberts Road, Subiaco, WA, 6008, Australia
    BMC Pharmacol Toxicol 14:13. 2013
  4. ncbi request reprint Risk factors for bronchiectasis in children with cystic fibrosis
    Peter D Sly
    Queensland Children s Medical Research Institute, Brisbane, Australia
    N Engl J Med 368:1963-70. 2013
  5. doi request reprint Medical research results in the general media: worthwhile and rewarding if presented well, potentially harmful if prepared poorly
    Peter D Sly
    Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Australia
    Paediatr Respir Rev 12:277-80. 2011
  6. doi request reprint Role of innate immunity in the development of allergy and asthma
    Peter D Sly
    Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia
    Curr Opin Allergy Clin Immunol 11:127-31. 2011
  7. ncbi request reprint Health impacts of climate change and biosecurity in the Asian Pacific region
    Peter D Sly
    Queensland Children s Medical Research Institute, University of Queensland, Royal Children s Hospital, Herston, Brisbane, Australia
    Rev Environ Health 26:7-12. 2011
  8. pmc Using mathematical transmission modelling to investigate drivers of respiratory syncytial virus seasonality in children in the Philippines
    Stuart Paynter
    School of Population Health, University of Queensland, Brisbane, Queensland, Australia
    PLoS ONE 9:e90094. 2014
  9. doi request reprint Reference ranges for Mexican preschool-aged children using the forced oscillation technique
    Claire Shackleton
    Queensland Children s Medical Research Institute, The University of Queensland, Brisbane, Australia
    Arch Bronconeumol 49:326-9. 2013
  10. doi request reprint Malnutrition: a risk factor for severe respiratory syncytial virus infection and hospitalization
    Stuart Paynter
    From the School of Population Health Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Australia Research Institute of Tropical Medicine, Manila, the Philippines Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland Barbara Hardy Institute, University of South Australia, Adelaide, Australia University of Colorado Denver, School of Medicine Center for Global Health, Colorado School of Public Health and Children s Hospital Colorado, Aurora, CO
    Pediatr Infect Dis J 33:267-71. 2014

Detail Information

Publications30

  1. doi request reprint The early origins of asthma: who is really at risk?
    Peter D Sly
    Deputy Director, Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Australia
    Curr Opin Allergy Clin Immunol 11:24-8. 2011
    ..This review will comment on the latest evidence in this field...
  2. pmc Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung disease
    Emmanuelle Fantino
    The Queensland Children s Medical Research Institute, The University of Queensland, Level 4, Foundation Building, Royal Children s Hospital, Herston Road, Herston, Brisbane, QLD 4059, Australia
    BMC Pulm Med 14:28. 2014
    ..The chitinase-like protein YKL-40 is raised in sputum and serum of adults with CF. We investigated YKL-40 in BAL, serum and urine to determine whether this reflected inflammation and infection in young children with CF...
  3. pmc In utero exposure to low dose arsenic via drinking water impairs early life lung mechanics in mice
    Kathryn A Ramsey
    Division of Clinical Sciences, Telethon Institute for Child Health Research, 100 Roberts Road, Subiaco, WA, 6008, Australia
    BMC Pharmacol Toxicol 14:13. 2013
    ..The aim of this study was to determine if in utero exposure to low dose arsenic via drinking water is capable of altering lung growth and postnatal lung mechanics...
  4. ncbi request reprint Risk factors for bronchiectasis in children with cystic fibrosis
    Peter D Sly
    Queensland Children s Medical Research Institute, Brisbane, Australia
    N Engl J Med 368:1963-70. 2013
    ..We sought to determine risk factors for the onset of bronchiectasis, using data collected by the Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF) intensive surveillance program...
  5. doi request reprint Medical research results in the general media: worthwhile and rewarding if presented well, potentially harmful if prepared poorly
    Peter D Sly
    Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Australia
    Paediatr Respir Rev 12:277-80. 2011
    ....
  6. doi request reprint Role of innate immunity in the development of allergy and asthma
    Peter D Sly
    Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia
    Curr Opin Allergy Clin Immunol 11:127-31. 2011
    ..The purpose of this review is to examine the role of innate immunity in the lungs in the development of allergy and asthma...
  7. ncbi request reprint Health impacts of climate change and biosecurity in the Asian Pacific region
    Peter D Sly
    Queensland Children s Medical Research Institute, University of Queensland, Royal Children s Hospital, Herston, Brisbane, Australia
    Rev Environ Health 26:7-12. 2011
    ..Strategies addressing the health impacts of climate change must incorporate the principles of social justice and equity within the region...
  8. pmc Using mathematical transmission modelling to investigate drivers of respiratory syncytial virus seasonality in children in the Philippines
    Stuart Paynter
    School of Population Health, University of Queensland, Brisbane, Queensland, Australia
    PLoS ONE 9:e90094. 2014
    ..The timing of the seasonal patterns of nutritional status and rainfall were both consistent with the estimated seasonal pattern of transmissibility and these are both plausible drivers of the seasonality of RSV in this setting. ..
  9. doi request reprint Reference ranges for Mexican preschool-aged children using the forced oscillation technique
    Claire Shackleton
    Queensland Children s Medical Research Institute, The University of Queensland, Brisbane, Australia
    Arch Bronconeumol 49:326-9. 2013
    ..We aimed to develop FOT reference ranges for preschool-aged Mexican children and to compare these with current FOT reference ranges...
  10. doi request reprint Malnutrition: a risk factor for severe respiratory syncytial virus infection and hospitalization
    Stuart Paynter
    From the School of Population Health Queensland Children s Medical Research Institute, University of Queensland, Brisbane, Australia Research Institute of Tropical Medicine, Manila, the Philippines Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland Barbara Hardy Institute, University of South Australia, Adelaide, Australia University of Colorado Denver, School of Medicine Center for Global Health, Colorado School of Public Health and Children s Hospital Colorado, Aurora, CO
    Pediatr Infect Dis J 33:267-71. 2014
    ..Children hospitalized with RSV lower respiratory infection represent those at the severe end of the disease spectrum...
  11. doi request reprint The impact of birth weight on peak lung function in young adults
    Sadasivam Suresh
    School of Population Health, University of Queensland, Brisbane, QLD, Australia
    Chest 142:1603-10. 2012
    ..A birth cohort provides the opportunity to study the association between birth weight and adult respiratory function...
  12. doi request reprint The importance of the local environment in the transmission of respiratory syncytial virus
    Stuart Paynter
    School of Population Health, University of Queensland, Brisbane, Australia Electronic address
    Sci Total Environ 493:521-5. 2014
    ....
  13. doi request reprint Seasonal immune modulation in humans: observed patterns and potential environmental drivers
    Stuart Paynter
    School of Population Health, University of Queensland, Brisbane, Australia Electronic address
    J Infect 70:1-10. 2015
    ..Cyclical fluctuations in host immunity have been proposed as a driver of respiratory infection seasonality, however few studies have attempted to directly assess whether or not seasonal immune modulation occurs in humans...
  14. doi request reprint Relationship between environmental exposures in children and adult lung disease: the case for outdoor exposures
    Manuel Soto-Martinez
    Department of Respiratory Medicine, Royal Children s Hospital, Australia
    Chron Respir Dis 7:173-86. 2010
    ..An understanding of how ambient exposures impact on normal lung growth and development will aid in understanding of how chronic respiratory diseases of adults develop and may lead to new preventative strategies...
  15. doi request reprint Providing feedback on adherence increases use of preventive medication by asthmatic children
    Scott W Burgess
    Department of Paediatrics, Redland Hospital, Brisbane, Queensland, 4163 Australia
    J Asthma 47:198-201. 2010
    ..Measuring adherence and providing feedback increases the use of preventive medication. A larger study is required to explore implications for disease control...
  16. doi request reprint Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezing
    John W Upham
    Telethon Institute for Child Health Research, West Perth, and Centre for Child Health Research, University of Western Australia, Perth, Australia
    J Allergy Clin Immunol 124:707-13.e2. 2009
    ..However, it is not known specifically whether changes in dendritic cells (DCs) during infancy antedate the development of respiratory tract infections, asthma, and related clinical phenotypes...
  17. doi request reprint Adolescent peer aggression and its association with mental health and substance use in an Australian cohort
    Sophie E Moore
    Children s Health and Environment Program, Queensland Children s Medical Research Institute, University of Queensland, Royal Children s Hospital, Herston, QLD, 4029, Australia
    J Adolesc 37:11-21. 2014
    ..These results show an independent temporal relationship between peer aggression and later mental health and substance use problems in adolescence. ..
  18. pmc Poor growth and pneumonia seasonality in infants in the Philippines: cohort and time series studies
    Stuart Paynter
    School of Population Health, University of Queensland, Brisbane, Queensland, Australia
    PLoS ONE 8:e67528. 2013
    ..Further investigation of the seasonal level association, in particular the estimation of the expected lag between seasonal undernutrition and increased pneumonia incidence, is recommended. ..
  19. doi request reprint Environmental exposures: an underrecognized contribution to noncommunicable diseases
    Rosana E Norman
    Children s Halth and Environment Program, Queenland Children s Medical Research Institute, The University of Queenland, Herston, Australia
    Rev Environ Health 28:59-65. 2013
    ....
  20. pmc Respiratory viral infections in children with asthma: do they matter and can we prevent them?
    Hamid Ahanchian
    The Queensland Children s Medical Research Institute, The University of Queensland, Brisbane, Australia
    BMC Pediatr 12:147. 2012
    ..Acute exacerbations are associated with decreased lung growth or accelerated loss of lung function and, as such, add substantially to both the cost and morbidity associated with asthma...
  21. doi request reprint Health consequences of exposure to e-waste: a systematic review
    Kristen Grant
    Children s Health and Environment Program, Queensland Children s Medical Research Institute, The University of Queensland, Herston, QLD, Australia
    Lancet Glob Health 1:e350-61. 2013
    ..We aimed to summarise the evidence for the association between such exposures and adverse health outcomes...
  22. pmc Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy
    Kirsten M Spann
    Clinical Medical Virology Centre, The University of Queensland, Herston, Queensland, Australia Sir Albert Sakzewski Virus Research Centre, Queensland Children s Hospital and Health District, Herston, Queensland, Australia Australian Infectious Disease Research Centre, Queensland, Australia
    Thorax 69:918-25. 2014
    ..Airway epithelial cells (AEC) from patients with asthma, appear to have an impaired interferon (IFN)-β and -λ response to infection with rhinovirus...
  23. doi request reprint Brief exposure to cigarette smoke impairs airway epithelial cell innate anti-viral defence
    Jayden Logan
    Children s Lung, Environment and Asthma Research Team, Queensland Children s Medical Research Institute, The University of Queensland, Brisbane, Australia
    Toxicol In Vitro 28:1430-5. 2014
    ..Human rhinovirus (hRV) infections commonly cause acute upper respiratory infections and asthma exacerbations. Environmental cigarette smoke exposure is associated with a significant increase in the risk for these infections in children...
  24. pmc Factors influencing the assessment of lung function in mice with influenza-induced lung disease
    Alexander N Larcombe
    Division of Clinical Sciences, Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth, WA, Australia Airway Physiology Imaging Research Group, Woolcock Institute of Medical Research, Sydney, NSW, Australia Department of Medical Physics and Informatics, University of Szeged, Szeged, Hungary Queensland Children s Medical Research Institute, University of Queensland, Brisbane, QLD, Australia
    Influenza Other Respir Viruses 7:889-94. 2013
    ..Driving signal frequencies and the method of model fitting may influence the results, especially in cases of severe lung disease or under severe bronchoconstriction...
  25. ncbi request reprint Lung function, bronchial responsiveness, and asthma in a community cohort of 6-year-old children
    Jacqui Joseph-Bowen
    Division of Clinical Sciences, Biostatiscs and Genetic Epidemiology, Population Sciences and Cell Biology, Telethon Institute for Child Health Research, University of Western, Australia, Perth, Australia
    Am J Respir Crit Care Med 169:850-4. 2004
    ..Lung function testing, including methacholine challenge, is feasible in 5- to 7-year-old children and has the potential to contribute to the clinical management of children with asthma...
  26. doi request reprint Clarithromycin therapy for patients with cystic fibrosis: a randomized controlled trial
    P Robinson
    Department of Respiratory Medicine, Royal Children s Hospital, Murdoch Children s Research Instutite, Australia
    Pediatr Pulmonol 47:551-7. 2012
    ..We conclude that clarithromycin is not effective in treating CF lung disease...
  27. doi request reprint Early-life risk factors for chronic nonrespiratory diseases
    Archana Chacko
    World Health Organization Collaborating Centre for Children s Health and Environment, Queensland Children s Medical Research Institute, The University of Queensland, Brisbane, Australia
    Eur Respir J 45:244-59. 2015
    ..We will highlight the potential overlap in environmental risks with respiratory diseases, and point out knowledge gaps and research opportunities. ..
  28. pmc Incentive device improves spacer technique but not clinical outcome in preschool children with asthma
    André Schultz
    School of Paediatrics and Child Health, University of Western, Perth, Western Australia, Australia
    J Paediatr Child Health 48:52-6. 2012
    ..To investigate the influence of an incentive device, the Funhaler, on spacer technique and symptom control in young children with asthma and recurrent wheeze...
  29. pmc Identification of IL6R and chromosome 11q13.5 as risk loci for asthma
    Manuel A R Ferreira
    The Queensland Institute of Medical Research, Brisbane, QLD, Australia
    Lancet 378:1006-14. 2011
    ..We aimed to identify novel genetic variants affecting asthma risk, since these might provide novel insights into molecular mechanisms underlying the disease...
  30. doi request reprint Assessing adherence and factors associated with adherence in young children with asthma
    Scott W Burgess
    Department of Paediatrics, Redland Hospital, Cleveland, Queensland, Australia
    Respirology 13:559-63. 2008
    ..However, few data exist regarding the accuracy of subjective measures of adherence and factors associated with adherence in young children...