Research Topics
| Danielle SkropetaSummaryAffiliation: University of Wollongong Country: Australia Publications
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Detail Information
Publications
Kinase inhibitors from marine spongesDanielle Skropeta
School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
Mar Drugs 9:2131-54. 2011..These compounds, which belong to diverse structural classes, are reviewed herein, and ordered based upon the kinase that they inhibit. Relevant synthetic studies on the marine natural product kinase inhibitors have also been included...
Deep-sea natural productsDanielle Skropeta
School of Chemistry, University of Wollongong, Wollongong, Australia
Nat Prod Rep 25:1131-66. 2008..Relevant synthetic studies on the deep-sea natural products have also been included...
The effect of individual N-glycans on enzyme activityDanielle Skropeta
School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
Bioorg Med Chem 17:2645-53. 2009....
N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agentsLidia Matesic
School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
Bioorg Med Chem 16:3118-24. 2008..The results allowed further development of structure-activity relationships. The compound 5,7-dibromo-N-(1-naphthylmethyl)-1H-indole-2,3-dione 5a was the most potent against U937 cells with an IC(50) value of 0.19 microM...
Kinase inhibitory, haemolytic and cytotoxic activity of three deep-water sponges from North Western Australia and their fatty acid compositionAna Zivanovic
School of Chemistry, University of Wollongong, NSW 2500, Australia
Nat Prod Commun 6:1921-4. 2011....
c-AMP dependent protein kinase A inhibitory activity of six algal extracts from southeastern Australia and their fatty acid compositionAna Zivanovic
School of Chemistry, University of Wollongong, NSW, 2500, Australia
Nat Prod Commun 7:923-6. 2012..Importantly, this study reveals that abundant and readily available marine algae are a new and relatively unexplored source of PKA inhibitory compounds...
N,O-isopropylidenated threonines as tools for peptide cyclization: application to the synthesis of mahafacyclin BNima Sayyadi
School of Chemistry, The University of Sydney, 2006 NSW, Australia
Org Lett 7:5497-9. 2005..Incorporation of an N,O-isopropylidenated threonine more than doubles the head-to-tail cyclization yield. The N,O-isopropylidene grouping is then readily disassembled to give the antimalarial cyclic peptide in high yield...
