Julie A Simpson

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. pmc Nonlinear mixed-effects modelling of in vitro drug susceptibility and molecular correlates of multidrug resistant Plasmodium falciparum
    Julie A Simpson
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia
    PLoS ONE 8:e69505. 2013
  2. ncbi request reprint A comparison of adiposity measures as predictors of all-cause mortality: the Melbourne Collaborative Cohort Study
    Julie A Simpson
    Cancer Epidemiology Centre, Council Council Victoria, and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Level 2 723 Swanston St, Carlton, Victoria 3053, Australia
    Obesity (Silver Spring) 15:994-1003. 2007
  3. ncbi request reprint A comparison of different methods for including 'age at menopause' in analyses of the association between hormone replacement therapy use and breast cancer
    Julie A Simpson
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne and the Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Melbourne, Australia
    J Fam Plann Reprod Health Care 33:11-6. 2007
  4. pmc Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients
    Julie A Simpson
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia
    PLoS Med 3:e444. 2006
  5. pmc Towards optimal design of anti-malarial pharmacokinetic studies
    Julie A Simpson
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Melbourne, Victoria, Australia
    Malar J 8:189. 2009
  6. pmc Meat consumption and risk of primary hip and knee joint replacement due to osteoarthritis: a prospective cohort study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, VIC 3004, Australia
    BMC Musculoskelet Disord 12:17. 2011
  7. pmc Relationship between body adiposity measures and risk of primary knee and hip replacement for osteoarthritis: a prospective cohort study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC 3004, Australia
    Arthritis Res Ther 11:R31. 2009
  8. doi request reprint 20/20--Alcohol and age-related macular degeneration: the Melbourne Collaborative Cohort Study
    Madeleine K M Adams
    Centre for Eye Research Australia, University of Melbourne Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia
    Am J Epidemiol 176:289-98. 2012
  9. doi request reprint Fat consumption and its association with age-related macular degeneration
    Elaine W T Chong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
    Arch Ophthalmol 127:674-80. 2009
  10. doi request reprint Evaluation of an FFQ for assessment of antioxidant intake using plasma biomarkers in an ethnically diverse population
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Public Health Nutr 12:2438-47. 2009

Detail Information

Publications46

  1. pmc Nonlinear mixed-effects modelling of in vitro drug susceptibility and molecular correlates of multidrug resistant Plasmodium falciparum
    Julie A Simpson
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia
    PLoS ONE 8:e69505. 2013
    ....
  2. ncbi request reprint A comparison of adiposity measures as predictors of all-cause mortality: the Melbourne Collaborative Cohort Study
    Julie A Simpson
    Cancer Epidemiology Centre, Council Council Victoria, and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Level 2 723 Swanston St, Carlton, Victoria 3053, Australia
    Obesity (Silver Spring) 15:994-1003. 2007
    ..Our goal was to examine five different measures of adiposity as predictors of all-cause mortality...
  3. ncbi request reprint A comparison of different methods for including 'age at menopause' in analyses of the association between hormone replacement therapy use and breast cancer
    Julie A Simpson
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne and the Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Melbourne, Australia
    J Fam Plann Reprod Health Care 33:11-6. 2007
    ....
  4. pmc Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients
    Julie A Simpson
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia
    PLoS Med 3:e444. 2006
    ..We studied the population pharmacokinetics of intra-rectal artesunate and the relationship with parasitological responses in patients with moderately severe falciparum malaria...
  5. pmc Towards optimal design of anti-malarial pharmacokinetic studies
    Julie A Simpson
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Melbourne, Victoria, Australia
    Malar J 8:189. 2009
    ....
  6. pmc Meat consumption and risk of primary hip and knee joint replacement due to osteoarthritis: a prospective cohort study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, VIC 3004, Australia
    BMC Musculoskelet Disord 12:17. 2011
    ..However, whether it affects the risk of knee and hip osteoarthritis is unknown. We performed a prospective cohort study to examine the relationship between meat consumption and risk of primary hip and knee replacement for osteoarthritis...
  7. pmc Relationship between body adiposity measures and risk of primary knee and hip replacement for osteoarthritis: a prospective cohort study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC 3004, Australia
    Arthritis Res Ther 11:R31. 2009
    ..It is unknown whether the adipose mass and the distribution of adipose mass are associated with the risk of primary knee and hip replacement for osteoarthritis. The aim of the present investigation was to examine this in a cohort study...
  8. doi request reprint 20/20--Alcohol and age-related macular degeneration: the Melbourne Collaborative Cohort Study
    Madeleine K M Adams
    Centre for Eye Research Australia, University of Melbourne Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia
    Am J Epidemiol 176:289-98. 2012
    ..The odds ratio for those drinking more than 20 g of alcohol per day for late AMD was 1.44 (95% confidence interval: 0.85, 2.45; P = 0.17). These results show a modest association between alcohol consumption and increased AMD risk...
  9. doi request reprint Fat consumption and its association with age-related macular degeneration
    Elaine W T Chong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
    Arch Ophthalmol 127:674-80. 2009
    ..To evaluate associations between past dietary fat intake and the prevalence of age-related macular degeneration (AMD)...
  10. doi request reprint Evaluation of an FFQ for assessment of antioxidant intake using plasma biomarkers in an ethnically diverse population
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Public Health Nutr 12:2438-47. 2009
    ....
  11. doi request reprint Can genetic associations change with age? CFH and age-related macular degeneration
    Madeleine K M Adams
    Centre for Eye Research Australia, University of Melbourne Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia
    Hum Mol Genet 21:5229-36. 2012
    ..These findings have important implications for predictive models for AMD and potentially other age-related diseases which extrapolate risks from older cohorts, as they assume homogeneity of association by age, which might not exist...
  12. pmc Assessing the utility of an anti-malarial pharmacokinetic-pharmacodynamic model for aiding drug clinical development
    Sophie Zaloumis
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, Melbourne School of Population Health, University of Melbourne, Level 3, 207 Bouverie St, Carlton, VIC 3053, Australia
    Malar J 11:303. 2012
    ..A comprehensive simulation study to assess the utility of a stage-specific pharmacokinetic-pharmacodynamic (PK-PD) model for predicting within-host parasite response was performed...
  13. doi request reprint Apolipoprotein E gene associations in age-related macular degeneration: the Melbourne Collaborative Cohort Study
    Madeleine K M Adams
    Center for Eye Research Australia, University of Melbourne Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia
    Am J Epidemiol 175:511-8. 2012
    ..77 (P = 0.005)). These results highlight the importance of stratifying by smoking status in elderly populations. Smokers who survive to old age may be more likely to possess unknown genotypes which modify exposure-disease associations...
  14. pmc The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: A systematic review and meta-analysis
    Freya J I Fowkes
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    PLoS Med 7:e1000218. 2010
    ..However, published evidence of the protective effect of these antibodies is conflicting...
  15. pmc Adolescents' use of purpose built shade in secondary schools: cluster randomised controlled trial
    Suzanne J Dobbinson
    Centre for Behavioural Research in Cancer, Cancer Council Victoria, 1 Rathdowne Street, Carlton, VIC 3053, Australia
    BMJ 338:b95. 2009
    ..To examine whether students use or avoid newly shaded areas created by shade sails installed at schools...
  16. pmc Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malaria
    Kris M Jamsen
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    Malar J 11:143. 2012
    ....
  17. ncbi request reprint Alcohol consumption and cardiovascular mortality accounting for possible misclassification of intake: 11-year follow-up of the Melbourne Collaborative Cohort Study
    Linton R Harriss
    Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
    Addiction 102:1574-85. 2007
    ..To investigate the relationship between usual daily alcohol intake, beverage type and drinking frequency on cardiovascular (CVD) and coronary heart disease (CHD) mortality, accounting for systematic misclassification of intake...
  18. doi request reprint Dietary omega-3 fatty acid and fish intake in the primary prevention of age-related macular degeneration: a systematic review and meta-analysis
    Elaine W T Chong
    Centre for Eye Research Australia, University of Melbourne, Victoria, Australia
    Arch Ophthalmol 126:826-33. 2008
    ..To systematically review the evidence on dietary omega-3 fatty acid and fish intake in the primary prevention of age-related macular degeneration (AMD)...
  19. doi request reprint Body weight at early and middle adulthood, weight gain and persistent overweight from early adulthood are predictors of the risk of total knee and hip replacement for osteoarthritis
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria 3004, Australia
    Rheumatology (Oxford) 52:1033-41. 2013
    ..To examine the relationships between weight at early and middle adulthood and adult weight gain and the risk of total knee and hip replacement for OA...
  20. doi request reprint Comparison of methods for imputing ordinal data using multivariate normal imputation: a case study of non-linear effects in a large cohort study
    Katherine J Lee
    Clinical Epidemiology and Biostatistics Unit, Murdoch Childrens Research Institute, Melbourne, Australia
    Stat Med 31:4164-74. 2012
    ..Imputing categorical variables (which are clearly non-normal) using MVN imputation is challenging, and several approaches have been suggested. However, it remains unclear which approach should be preferred...
  21. doi request reprint Association between latitude and allergic diseases: a longitudinal study from childhood to middle-age
    Vicka Oktaria
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Melbourne, Australia
    Ann Allergy Asthma Immunol 110:80-5.e1. 2013
    ..Worldwide variations in allergy prevalence suggest that geographic factors may contribute to asthma. Ecologic studies have suggested that latitude, a marker of UV-B exposure and allergen exposures, may be related to clinical allergies...
  22. doi request reprint HFE C282Y homozygosity is associated with an increased risk of total hip replacement for osteoarthritis
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria, Australia
    Semin Arthritis Rheum 41:872-8. 2012
    ..Total joint replacement is considered a surrogate measure for symptomatic end-stage osteoarthritis. We examined the relationship between HFE gene mutations and risk of total hip and knee replacement using a prospective cohort study...
  23. pmc Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria
    Kris M Jamsen
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    Malar J 10:181. 2011
    ..In this work optimal design methods were used to determine sampling designs for typical future population PK studies of dihydroartemisinin, the principal biologically active metabolite of oral artesunate...
  24. pmc Reduced rates of primary joint replacement for osteoarthritis in Italian and Greek migrants to Australia: the Melbourne Collaborative Cohort Study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, VIC 3004, Australia
    Arthritis Res Ther 11:R86. 2009
    ..The aim of this study was to compare the rates of primary joint replacement for osteoarthritis for Italian and Greek migrants to Australia and Australian-born individuals...
  25. doi request reprint Red meat and chicken consumption and its association with age-related macular degeneration
    Elaine W T Chong
    Centre for Eye Research Australia, University of Melbourne, 32 Gisborne Street, East Melbourne 3002, Victoria, Australia
    Am J Epidemiol 169:867-76. 2009
    ..43, 95% confidence interval: 0.20, 0.91; P-trend = 0.007). These results suggest that different meats may differently affect AMD risk and may be a target for lifestyle modification...
  26. pmc New insights into acquisition, boosting, and longevity of immunity to malaria in pregnant women
    Freya J I Fowkes
    Macfarlane Burnet Institute of Medical Research, Melbourne, Australia
    J Infect Dis 206:1612-21. 2012
    ..How antimalarial antibodies are acquired and maintained during pregnancy and boosted after reinfection with Plasmodium falciparum and Plasmodium vivax is unknown...
  27. doi request reprint Alcohol consumption and the risk of age-related macular degeneration: a systematic review and meta-analysis
    Elaine W T Chong
    Centre for Eye Research Australia, The University of Melbourne, Victoria, Australia
    Am J Ophthalmol 145:707-715. 2008
    ..To review systematically the evidence currently available on alcohol consumption and the risk of age-related macular degeneration (AMD)...
  28. ncbi request reprint Observed use of sunglasses in public outdoor settings around Melbourne, Australia: 1993 to 2002
    Magdalena Lagerlund
    Centre for Behavioural Research in Cancer, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
    Prev Med 42:291-6. 2006
    ..Wearing sunglasses may reduce the risk of cataract and of skin cancer in the periorbital area. Understanding predictors of sunglasses use may help identify groups with lower usage patterns...
  29. ncbi request reprint Plasma phospholipid fatty acid composition as a biomarker of habitual dietary fat intake in an ethnically diverse cohort
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Nutr Metab Cardiovasc Dis 17:415-26. 2007
    ....
  30. ncbi request reprint Dietary carbohydrate, fibre, glycaemic index, glycaemic load and the risk of postmenopausal breast cancer
    Graham G Giles
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Int J Cancer 118:1843-7. 2006
    ..43, 0.99), p = 0.005. Our data do not support a strong role for GI and GL in breast carcinogenesis but suggest that increased intake of fibre and carbohydrate may be associated with the diagnosis of cancers of more favourable prognosis...
  31. doi request reprint Incidence of total knee and hip replacement for osteoarthritis in relation to the metabolic syndrome and its components: A prospective cohort study
    Sultana Monira Hussain
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria 3004, Australia
    Semin Arthritis Rheum 43:429-36. 2014
    ....
  32. ncbi request reprint Ultraviolet radiation at places of residence and the development of melanocytic nevi in children (Australia)
    Dallas R English
    Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne St, 3053, Carlton, Vic, Australia
    Cancer Causes Control 17:103-7. 2006
    ..To investigate the relationship between ambient ultraviolet radiation (UV) exposure and number of melanocytic nevi in children...
  33. pmc A robust design for identification of the Parasite Clearance Estimator
    Kris M Jamsen
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Australia
    Malar J 12:410. 2013
    ....
  34. pmc Decreasing burden of malaria in pregnancy in Malawian women and its relationship to use of intermittent preventive therapy or bed nets
    Gaoqian Feng
    Department of Medicine RMH WH, Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Melbourne, Australia
    PLoS ONE 5:e12012. 2010
    ..Longitudinal data of malaria prevalence and pregnancy outcomes are valuable in gauging the impact of these antimalarial interventions...
  35. pmc Acquisition of growth-inhibitory antibodies against blood-stage Plasmodium falciparum
    Fiona J McCallum
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    PLoS ONE 3:e3571. 2008
    ..Antibodies that inhibit the growth of blood-stage Plasmodium falciparum may play an important role in acquired and vaccine-induced immunity in humans. However, the acquisition and activity of these antibodies is not well understood...
  36. pmc A review of the reporting and handling of missing data in cohort studies with repeated assessment of exposure measures
    Amalia Karahalios
    Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Vic, Australia
    BMC Med Res Methodol 12:96. 2012
    ..We have conducted a review of publications from cohort studies in order to document the reporting of missing data for exposure measures and to describe the statistical methods used to account for the missing data...
  37. pmc Antibodies to variant surface antigens of Plasmodium falciparum-infected erythrocytes are associated with protection from treatment failure and the development of anemia in pregnancy
    Gaoqian Feng
    Department of Medicine, Royal Melbourne Hospital, Melbourne, Australia
    J Infect Dis 200:299-306. 2009
    ..Antibodies to VSA-PAM develop with gravidity and block placental adhesion or opsonize IEs for phagocytic clearance, helping to prevent maternal anemia and low birth weight in infants...
  38. pmc Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone
    Julie A Simpson
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Br J Clin Pharmacol 61:289-300. 2006
    ....
  39. doi request reprint Implications of the licensure of a partially efficacious malaria vaccine on evaluating second-generation vaccines
    Freya J I Fowkes
    Macfarlane Burnet Institute of Medical Research, 85 Commercial Road, Melbourne, Victoria 3004, Australia
    BMC Med 11:232. 2013
    ..2 million deaths annually attributed to malaria. Development of a highly efficacious malaria vaccine will offer unparalleled possibilities for disease prevention and remains a key priority for long-term malaria control and elimination...
  40. doi request reprint The impact of breastfeeding on lung development and function: a systematic review
    Nilakshi T Waidyatillake
    Centre for Molecular, Environmental, Genetic and Analytic MEGA Epidemiology, Melbourne School of Population and Global Health, The University of Melbourne, 207, Bouverie Street, Carlton, VIC 3052, Australia
    Expert Rev Clin Immunol 9:1253-65. 2013
    ..Further research is needed to determine the specific details such as duration and type (exclusive vs partial) of breastfeeding that leads to improved lung function...
  41. pmc Altered temporal response of malaria parasites determines differential sensitivity to artemisinin
    Nectarios Klonis
    Department of Biochemistry and Molecular Biology and Australian Research Council Centre of Excellence for Coherent X Ray Science, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010, Australia
    Proc Natl Acad Sci U S A 110:5157-62. 2013
    ....
  42. doi request reprint Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype
    Dallas R English
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, The University of Melbourne, Level 1, Parkville, Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 17:1774-80. 2008
    ....
  43. pmc Impact of tobacco control policies and mass media campaigns on monthly adult smoking prevalence
    Melanie A Wakefield
    Centre for Behavioral Research in Cancer, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
    Am J Public Health 98:1443-50. 2008
    ..We sought to assess the impact of several tobacco control policies and televised antismoking advertising on adult smoking prevalence...
  44. ncbi request reprint Sun protection and the development of melanocytic nevi in children
    Dallas R English
    The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 14:2873-6. 2005
    ..Using sunscreen on the back when it was uncovered was not associated with number of nevi (P = 0.59). Children who stayed indoors in the middle of the day and wore clothing while outdoors had fewer nevi...
  45. pmc Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis
    Elaine W T Chong
    Centre for Eye Research Australia, University of Melbourne, Victoria 3002, Australia
    BMJ 335:755. 2007
    ..To evaluate the effectiveness of dietary antioxidants in the primary prevention of age related macular degeneration (AMD)...
  46. doi request reprint Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial
    Kerrie M Sanders
    Department of Clinical and Biomedical Sciences, Barwon Health, University of Melbourne, Geelong, Victoria, Australia 3220
    JAMA 303:1815-22. 2010
    ..Improving vitamin D status may be an important modifiable risk factor to reduce falls and fractures; however, adherence to daily supplementation is typically poor...