Research Topics
| L A SimonsSummaryAffiliation: University of New South Wales Country: Australia Publications
| Collaborators |
Detail Information
Publications
Beneficial effect on average lipid levels from energy restriction and fat loss in obese individuals with or without type 2 diabetesT P Markovic
Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, Australia
Diabetes Care 21:695-700. 1998..We investigated whether energy restriction or modest fat loss improved the lipid profile in obese subjects with and without type 2 diabetes. The relationship of site of adipose tissue loss to lipid changes was also examined...- Predictors of long-term mortality in the elderly: the Dubbo StudyL A Simons
University of NSW, Lipid Research Department, St Vincent s Hospital, Sydney, New South Wales, Australia
Intern Med J 41:555-60. 2011..This study examines the predictors of long-term all-causes mortality (ACM) in Australian senior citizens... - Risk functions for prediction of cardiovascular disease in elderly Australians: the Dubbo StudyLeon A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
Med J Aust 178:113-6. 2003..To evaluate a Framingham risk function for coronary heart disease in an elderly Australian cohort and to derive a risk function for cardiovascular disease (CVD) in elderly Australians... - Impact of smoking, diabetes and hypertension on survival time in the elderly: the Dubbo StudyLeon A Simons
Lipid Research Department, University of New South Wales, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
Med J Aust 182:219-22. 2005..To study the impact of various risk factors on survival time in a cohort of elderly Australians... - Additive effect of plant sterol-ester margarine and cerivastatin in lowering low-density lipoprotein cholesterol in primary hypercholesterolemiaLeon A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, Australia
Am J Cardiol 90:737-40. 2002..The addition of sterol-ester margarine to statin therapy offers LDL cholesterol reduction equivalent to doubling the dose of statin... - Risk factors for acute myocardial infarction in the elderly (the Dubbo study)Leon A Simons
University of New South Wales Lipid Research Department, St Vincent's Hospital, Sydney, Australia
Am J Cardiol 89:69-72. 2002 - Cholesterol and other lipids predict coronary heart disease and ischaemic stroke in the elderly, but only in those below 70 yearsL A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, NSW, Darlinghurst, Australia
Atherosclerosis 159:201-8. 2001..The findings support a case for cholesterol testing in older subjects up to 70 years, in whom there is ancillary evidence of CHD and stroke prevention through treatment designed to reduce LDL cholesterol... - Moderate alcohol intake is associated with survival in the elderly: the Dubbo StudyL A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, NSW
Med J Aust 173:121-4. 2000..To examine the relationship between alcohol intake and survival in elderly people... - Phytoestrogens do not influence lipoprotein levels or endothelial function in healthy, postmenopausal womenL A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, Australia
Am J Cardiol 85:1297-301. 2000..3% vs 13.7 +/- 1.2%, p >0.1). These results fail to show a significant impact of medium-term supplementation with 80 mg/day of isoflavones on lipid and lipoprotein levels or on endothelial function in healthy, postmenopausal women... - Fasting plasma glucose in non-diabetic elderly women predicts increased all-causes mortality and coronary heart disease riskL A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney
Aust N Z J Med 30:41-7. 2000..To confirm the hypothesis that upper normal plasma glucose levels in non-diabetic subjects are independently predictive of mortality and cardiovascular disease (CVD)... - Healthy ageing is associated with reduced and delayed disabilityL A Simons
University of NSW Lipid Research Department, St Vincent s Hospital, Darlinghurst, Sydney, Australia
Age Ageing 29:143-8. 2000..to identify subgroups within the population with reduced or delayed disability during healthy ageing... - Choosing the most appropriate therapy for lipid disordersL A Simons
Lipid Research Department, St Vincent s Hospital, Sydney, New South Wales
Aust Fam Physician 29:199-203. 2000..As the range of medications available increases, choosing the appropriate therapy for a patient becomes more difficult... - Lipid-modifying drugsLeon A Simons
University of South Wales, Lipid Research Department, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
Med J Aust 182:286-9. 2005..Side-effects are infrequent and usually mild, but widespread use of lipid-modifying medication demands caution because of the possibility of muscle or liver dysfunction or drug interactions... - Effect of Lactobacillus fermentum on serum lipids in subjects with elevated serum cholesterolLeon A Simons
School of Medicine, University of NSW, Sydney, NSW, Australia
Nutr Metab Cardiovasc Dis 16:531-5. 2006..There is increasing interest in the use of natural therapies to reduce elevated low density lipoprotein (LDL) cholesterol. This study assessed the effects of PCC Lactobacillus fermentum on LDL cholesterol and other lipid fractions... - Ezetimibe added to statin therapy (EASY study) - an evaluation by Australian general practitionersLeon A Simons
University of New South Wales, Lipid Research Department, St Vincent s Hospital, Sydney, New South Wales, Australia
Aust Fam Physician 36:90-2, 96. 2007..5 mmol/L when ezetimibe was added to existing statin monotherapy under Pharmaceutical Benefits Scheme (PBS) guidelines in a general practice setting... - Does a diagnosis of the metabolic syndrome provide additional prediction of cardiovascular disease and total mortality in the elderly? The Dubbo StudyLeon A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, NSW
Med J Aust 186:400-3. 2007..To assess whether a diagnosis of the metabolic syndrome (MetS) improves the prediction of cardiovascular disease or total mortality beyond that already provided by conventional risk factors... - Effects of ezetimibe added to on-going statin therapy on the lipid profile of hypercholesterolemic patients with diabetes mellitus or metabolic syndromeLeon Simons
University of NSW and St Vincent s Hospital, Darlinghurst, NSW, Australia
Curr Med Res Opin 20:1437-45. 2004..To conduct a post-hoc assessment of the lipid-modifying effects of adding the cholesterol absorption inhibitor, ezetimibe, to on-going statin therapy in patients with diabetes mellitus (DM) or metabolic syndrome (MetS)... - Successful management of primary hypercholesterolaemia with simvastatin and low-dose colestipolL A Simons
University of New South Wales, School of Medicine, Darlinghurst
Med J Aust 157:455-9. 1992.... - Vitamin E ingestion does not improve arterial endothelial dysfunction in older adultsL A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, Darlinghurst NSW, Australia
Atherosclerosis 143:193-9. 1999..7+/-1.3% versus 13.6+/-1.4%,). These results exclude a major impact of medium-term supplementation with vitamin E on arterial endothelial function when age-related dysfunction is already present... - Effects of atorvastatin monotherapy and simvastatin plus cholestyramine on arterial endothelial function in patients with severe primary hypercholesterolaemiaL A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, Darlinghurst, Australia
Atherosclerosis 137:197-203. 1998..54, P < 0.001). Endothelial dysfunction in primary hypercholesterolaemia was improved by treatment with atorvastatin or simvastatin plus cholestyramine and this effect may result in the prevention of future coronary events... - Risk factors for ischemic stroke: Dubbo Study of the elderlyL A Simons
University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, NSW, Australia
Stroke 29:1341-6. 1998..We report on 98 months' follow-up in a prospective study of cardiovascular disease in the Australian elderly, the Dubbo Study... - The effects of adrenergic blockade on lipoproteins using the rat as an experimental modelS Balasubramaniam
University of N S W School of Medicine, St Vincent s Hospital, Sydney, Australia
Artery 17:60-70. 1990..It appears that beta 2 receptor exposure or stimulation may be one of the key points in the interaction between adrenergic blockade and lipoprotein metabolism... - Usefulness of fasting plasma glucose to predict mortality or coronary heart disease in persons > or = 60 years of age without diabetes mellitus or in those with undiagnosed diabetes mellitus (from The Dubbo Study)Leon A Simons
University of NSW Lipid Research Department, St Vincent s Hospital, Sydney NSW Australia
Am J Cardiol 102:831-4. 2008..No similar findings were made in men... - A comparison of risk factors for coronary heart disease and ischaemic stroke: the Dubbo study of Australian elderlyLeon A Simons
Lipid Research Department, University of NSW, St Vincent s Hospital, Sydney, Darlinghurst, NSW 2010, Australia
Heart Lung Circ 18:330-3. 2009..Conventional risk factors for coronary heart disease (CHD) and ischaemic stroke (IS) have been well documented. This study examines whether there is a unique pattern of risk factors for each disease... - Persistence with antihypertensive medication: Australia-wide experience, 2004-2006Leon A Simons
Lipid Research Department, University of New South Wales, St Vincent s Hospital, Sydney, NSW, Australia
Med J Aust 188:224-7. 2008..To study persistence and adherence with the use of common antihypertensive (AHT) medications... - Lifestyle factors and risk of dementia: Dubbo Study of the elderlyLeon A Simons
Lipid Research Department, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
Med J Aust 184:68-70. 2006..To identify risk factors for dementia in an elderly Australian cohort... - Generic substitution of commonly used medications: Australia-wide experience, 2007-2008Michael Ortiz
Solvay Pharmaceuticals, Sydney, NSW, Australia
Med J Aust 192:370-3. 2010..To study the extent of brand substitution and switching in three commonly used classes of drugs available on the Pharmaceutical Benefits Scheme (PBS)... - Comparison of usefulness of systolic, diastolic, and mean blood pressure and pulse pressure as predictors of cardiovascular death in patients >/=60 years of age (The Dubbo Study)Latha Palaniappan
University of New South Wales Lipid Research Department, St. Vincent's Hospital, Sydney, Australia
Am J Cardiol 90:1398-401. 2002 - Private lives and public programs: an Australian longitudinal study of the elderlyJohn McCallum
Victoria University, Melbourne, Australia
J Aging Soc Policy 19:87-103. 2007..The critical challenge will be to harmoniously grow public financing, private funding, and informal caregiving to deal with the growing burden arising from an aging society... - Delaying dementia and nursing home placement: the Dubbo study of elderly Australians over a 14-year follow-upJohn McCallum
Victoria University, PO Box 14428, Melbourne, Victoria 8001, Australia
Ann N Y Acad Sci 1114:121-9. 2007....