L A Simons

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi request reprint Beneficial effect on average lipid levels from energy restriction and fat loss in obese individuals with or without type 2 diabetes
    T P Markovic
    Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, Australia
    Diabetes Care 21:695-700. 1998
  2. doi request reprint Predictors of long-term mortality in the elderly: the Dubbo Study
    L A Simons
    University of NSW, Lipid Research Department, St Vincent s Hospital, Sydney, New South Wales, Australia
    Intern Med J 41:555-60. 2011
  3. pmc Risk functions for prediction of cardiovascular disease in elderly Australians: the Dubbo Study
    Leon A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
    Med J Aust 178:113-6. 2003
  4. ncbi request reprint Impact of smoking, diabetes and hypertension on survival time in the elderly: the Dubbo Study
    Leon A Simons
    Lipid Research Department, University of New South Wales, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
    Med J Aust 182:219-22. 2005
  5. ncbi request reprint Additive effect of plant sterol-ester margarine and cerivastatin in lowering low-density lipoprotein cholesterol in primary hypercholesterolemia
    Leon A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, Australia
    Am J Cardiol 90:737-40. 2002
  6. ncbi request reprint Risk factors for acute myocardial infarction in the elderly (the Dubbo study)
    Leon A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, Australia
    Am J Cardiol 89:69-72. 2002
  7. ncbi request reprint Cholesterol and other lipids predict coronary heart disease and ischaemic stroke in the elderly, but only in those below 70 years
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, NSW, Darlinghurst, Australia
    Atherosclerosis 159:201-8. 2001
  8. ncbi request reprint Moderate alcohol intake is associated with survival in the elderly: the Dubbo Study
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, NSW
    Med J Aust 173:121-4. 2000
  9. ncbi request reprint Phytoestrogens do not influence lipoprotein levels or endothelial function in healthy, postmenopausal women
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, Australia
    Am J Cardiol 85:1297-301. 2000
  10. ncbi request reprint Fasting plasma glucose in non-diabetic elderly women predicts increased all-causes mortality and coronary heart disease risk
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney
    Aust N Z J Med 30:41-7. 2000

Detail Information

Publications30

  1. ncbi request reprint Beneficial effect on average lipid levels from energy restriction and fat loss in obese individuals with or without type 2 diabetes
    T P Markovic
    Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, Australia
    Diabetes Care 21:695-700. 1998
    ..We investigated whether energy restriction or modest fat loss improved the lipid profile in obese subjects with and without type 2 diabetes. The relationship of site of adipose tissue loss to lipid changes was also examined...
  2. doi request reprint Predictors of long-term mortality in the elderly: the Dubbo Study
    L A Simons
    University of NSW, Lipid Research Department, St Vincent s Hospital, Sydney, New South Wales, Australia
    Intern Med J 41:555-60. 2011
    ..This study examines the predictors of long-term all-causes mortality (ACM) in Australian senior citizens...
  3. pmc Risk functions for prediction of cardiovascular disease in elderly Australians: the Dubbo Study
    Leon A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
    Med J Aust 178:113-6. 2003
    ..To evaluate a Framingham risk function for coronary heart disease in an elderly Australian cohort and to derive a risk function for cardiovascular disease (CVD) in elderly Australians...
  4. ncbi request reprint Impact of smoking, diabetes and hypertension on survival time in the elderly: the Dubbo Study
    Leon A Simons
    Lipid Research Department, University of New South Wales, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
    Med J Aust 182:219-22. 2005
    ..To study the impact of various risk factors on survival time in a cohort of elderly Australians...
  5. ncbi request reprint Additive effect of plant sterol-ester margarine and cerivastatin in lowering low-density lipoprotein cholesterol in primary hypercholesterolemia
    Leon A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, Australia
    Am J Cardiol 90:737-40. 2002
    ..The addition of sterol-ester margarine to statin therapy offers LDL cholesterol reduction equivalent to doubling the dose of statin...
  6. ncbi request reprint Risk factors for acute myocardial infarction in the elderly (the Dubbo study)
    Leon A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, Australia
    Am J Cardiol 89:69-72. 2002
  7. ncbi request reprint Cholesterol and other lipids predict coronary heart disease and ischaemic stroke in the elderly, but only in those below 70 years
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, NSW, Darlinghurst, Australia
    Atherosclerosis 159:201-8. 2001
    ..The findings support a case for cholesterol testing in older subjects up to 70 years, in whom there is ancillary evidence of CHD and stroke prevention through treatment designed to reduce LDL cholesterol...
  8. ncbi request reprint Moderate alcohol intake is associated with survival in the elderly: the Dubbo Study
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, NSW
    Med J Aust 173:121-4. 2000
    ..To examine the relationship between alcohol intake and survival in elderly people...
  9. ncbi request reprint Phytoestrogens do not influence lipoprotein levels or endothelial function in healthy, postmenopausal women
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, Australia
    Am J Cardiol 85:1297-301. 2000
    ..3% vs 13.7 +/- 1.2%, p >0.1). These results fail to show a significant impact of medium-term supplementation with 80 mg/day of isoflavones on lipid and lipoprotein levels or on endothelial function in healthy, postmenopausal women...
  10. ncbi request reprint Fasting plasma glucose in non-diabetic elderly women predicts increased all-causes mortality and coronary heart disease risk
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney
    Aust N Z J Med 30:41-7. 2000
    ..To confirm the hypothesis that upper normal plasma glucose levels in non-diabetic subjects are independently predictive of mortality and cardiovascular disease (CVD)...
  11. ncbi request reprint Healthy ageing is associated with reduced and delayed disability
    L A Simons
    University of NSW Lipid Research Department, St Vincent s Hospital, Darlinghurst, Sydney, Australia
    Age Ageing 29:143-8. 2000
    ..to identify subgroups within the population with reduced or delayed disability during healthy ageing...
  12. ncbi request reprint Choosing the most appropriate therapy for lipid disorders
    L A Simons
    Lipid Research Department, St Vincent s Hospital, Sydney, New South Wales
    Aust Fam Physician 29:199-203. 2000
    ..As the range of medications available increases, choosing the appropriate therapy for a patient becomes more difficult...
  13. ncbi request reprint Lipid-modifying drugs
    Leon A Simons
    University of South Wales, Lipid Research Department, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
    Med J Aust 182:286-9. 2005
    ..Side-effects are infrequent and usually mild, but widespread use of lipid-modifying medication demands caution because of the possibility of muscle or liver dysfunction or drug interactions...
  14. ncbi request reprint Effect of Lactobacillus fermentum on serum lipids in subjects with elevated serum cholesterol
    Leon A Simons
    School of Medicine, University of NSW, Sydney, NSW, Australia
    Nutr Metab Cardiovasc Dis 16:531-5. 2006
    ..There is increasing interest in the use of natural therapies to reduce elevated low density lipoprotein (LDL) cholesterol. This study assessed the effects of PCC Lactobacillus fermentum on LDL cholesterol and other lipid fractions...
  15. ncbi request reprint Ezetimibe added to statin therapy (EASY study) - an evaluation by Australian general practitioners
    Leon A Simons
    University of New South Wales, Lipid Research Department, St Vincent s Hospital, Sydney, New South Wales, Australia
    Aust Fam Physician 36:90-2, 96. 2007
    ..5 mmol/L when ezetimibe was added to existing statin monotherapy under Pharmaceutical Benefits Scheme (PBS) guidelines in a general practice setting...
  16. ncbi request reprint Does a diagnosis of the metabolic syndrome provide additional prediction of cardiovascular disease and total mortality in the elderly? The Dubbo Study
    Leon A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, NSW
    Med J Aust 186:400-3. 2007
    ..To assess whether a diagnosis of the metabolic syndrome (MetS) improves the prediction of cardiovascular disease or total mortality beyond that already provided by conventional risk factors...
  17. ncbi request reprint Effects of ezetimibe added to on-going statin therapy on the lipid profile of hypercholesterolemic patients with diabetes mellitus or metabolic syndrome
    Leon Simons
    University of NSW and St Vincent s Hospital, Darlinghurst, NSW, Australia
    Curr Med Res Opin 20:1437-45. 2004
    ..To conduct a post-hoc assessment of the lipid-modifying effects of adding the cholesterol absorption inhibitor, ezetimibe, to on-going statin therapy in patients with diabetes mellitus (DM) or metabolic syndrome (MetS)...
  18. ncbi request reprint Successful management of primary hypercholesterolaemia with simvastatin and low-dose colestipol
    L A Simons
    University of New South Wales, School of Medicine, Darlinghurst
    Med J Aust 157:455-9. 1992
    ....
  19. ncbi request reprint Vitamin E ingestion does not improve arterial endothelial dysfunction in older adults
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Darlinghurst NSW, Australia
    Atherosclerosis 143:193-9. 1999
    ..7+/-1.3% versus 13.6+/-1.4%,). These results exclude a major impact of medium-term supplementation with vitamin E on arterial endothelial function when age-related dysfunction is already present...
  20. ncbi request reprint Effects of atorvastatin monotherapy and simvastatin plus cholestyramine on arterial endothelial function in patients with severe primary hypercholesterolaemia
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Darlinghurst, Australia
    Atherosclerosis 137:197-203. 1998
    ..54, P < 0.001). Endothelial dysfunction in primary hypercholesterolaemia was improved by treatment with atorvastatin or simvastatin plus cholestyramine and this effect may result in the prevention of future coronary events...
  21. ncbi request reprint Risk factors for ischemic stroke: Dubbo Study of the elderly
    L A Simons
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, NSW, Australia
    Stroke 29:1341-6. 1998
    ..We report on 98 months' follow-up in a prospective study of cardiovascular disease in the Australian elderly, the Dubbo Study...
  22. ncbi request reprint The effects of adrenergic blockade on lipoproteins using the rat as an experimental model
    S Balasubramaniam
    University of N S W School of Medicine, St Vincent s Hospital, Sydney, Australia
    Artery 17:60-70. 1990
    ..It appears that beta 2 receptor exposure or stimulation may be one of the key points in the interaction between adrenergic blockade and lipoprotein metabolism...
  23. doi request reprint Usefulness of fasting plasma glucose to predict mortality or coronary heart disease in persons > or = 60 years of age without diabetes mellitus or in those with undiagnosed diabetes mellitus (from The Dubbo Study)
    Leon A Simons
    University of NSW Lipid Research Department, St Vincent s Hospital, Sydney NSW Australia
    Am J Cardiol 102:831-4. 2008
    ..No similar findings were made in men...
  24. doi request reprint A comparison of risk factors for coronary heart disease and ischaemic stroke: the Dubbo study of Australian elderly
    Leon A Simons
    Lipid Research Department, University of NSW, St Vincent s Hospital, Sydney, Darlinghurst, NSW 2010, Australia
    Heart Lung Circ 18:330-3. 2009
    ..Conventional risk factors for coronary heart disease (CHD) and ischaemic stroke (IS) have been well documented. This study examines whether there is a unique pattern of risk factors for each disease...
  25. ncbi request reprint Persistence with antihypertensive medication: Australia-wide experience, 2004-2006
    Leon A Simons
    Lipid Research Department, University of New South Wales, St Vincent s Hospital, Sydney, NSW, Australia
    Med J Aust 188:224-7. 2008
    ..To study persistence and adherence with the use of common antihypertensive (AHT) medications...
  26. ncbi request reprint Lifestyle factors and risk of dementia: Dubbo Study of the elderly
    Leon A Simons
    Lipid Research Department, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
    Med J Aust 184:68-70. 2006
    ..To identify risk factors for dementia in an elderly Australian cohort...
  27. ncbi request reprint Generic substitution of commonly used medications: Australia-wide experience, 2007-2008
    Michael Ortiz
    Solvay Pharmaceuticals, Sydney, NSW, Australia
    Med J Aust 192:370-3. 2010
    ..To study the extent of brand substitution and switching in three commonly used classes of drugs available on the Pharmaceutical Benefits Scheme (PBS)...
  28. pmc Comparison of usefulness of systolic, diastolic, and mean blood pressure and pulse pressure as predictors of cardiovascular death in patients >/=60 years of age (The Dubbo Study)
    Latha Palaniappan
    University of New South Wales Lipid Research Department, St Vincent s Hospital, Sydney, Australia
    Am J Cardiol 90:1398-401. 2002
  29. ncbi request reprint Private lives and public programs: an Australian longitudinal study of the elderly
    John McCallum
    Victoria University, Melbourne, Australia
    J Aging Soc Policy 19:87-103. 2007
    ..The critical challenge will be to harmoniously grow public financing, private funding, and informal caregiving to deal with the growing burden arising from an aging society...
  30. ncbi request reprint Delaying dementia and nursing home placement: the Dubbo study of elderly Australians over a 14-year follow-up
    John McCallum
    Victoria University, PO Box 14428, Melbourne, Victoria 8001, Australia
    Ann N Y Acad Sci 1114:121-9. 2007
    ....