Stephan A Schug

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi Opioid and non-opioid analgesics
    Stephan A Schug
    Anaesthesia in Pharmacology, University of Western Australia, MRF Building, Royal Perth Hospital, GPO Box X2213, Perth WA 6847, Australia
    Best Pract Res Clin Anaesthesiol 17:91-110. 2003
  2. pmc The role of tramadol in current treatment strategies for musculoskeletal pain
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia and Department of Anaesthesia and Pain Medicine, Royal Perth Hospital Perth, Western Australia
    Ther Clin Risk Manag 3:717-23. 2007
  3. ncbi Combination analgesia in 2005 - a rational approach: focus on paracetamol-tramadol
    Stephan A Schug
    School of Medicine and Pharmacology, The University of Western Australia, Level 2, MRF Building G Block Royal Perth Hospital, GPO Box X2213 Perth, WA 6847, Australia
    Clin Rheumatol 25:S16-21. 2006
  4. ncbi The role of COX-2 inhibitors in the treatment of postoperative pain
    Stephan A Schug
    School of Medicine and Pharmacology, The University of Western Australia, and Royal Perth Hospital, MRF Building at RPH, GPO Box X2213, Perth WA 6847, Australia
    J Cardiovasc Pharmacol 47:S82-6. 2006
  5. ncbi Update on the role of non-opioids for postoperative pain treatment
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, MRF Building, Royal Perth Hospital, GPO Box X2213, Perth, WA 6847, Australia
    Best Pract Res Clin Anaesthesiol 21:15-30. 2007
  6. ncbi Neuraxial drug administration: a review of treatment options for anaesthesia and analgesia
    Stephan A Schug
    Pharmacology Unit, School of Medicine and Pharmacology, UWA Anaesthesia, University of Western Australia, Perth, WA, Australia
    CNS Drugs 20:917-33. 2006
  7. doi Predictors of patient satisfaction with pain management and improvement 3 months after burn injury
    Rachel M Andrews
    McComb Research Foundation, Western Australia, Australia
    J Burn Care Res 33:442-52. 2012
  8. doi A pilot randomized controlled trial of an early multidisciplinary model to prevent disability following traumatic injury
    Allyson L Browne
    Statewide Trauma Service of Western Australia, Royal Perth Hospital, Western Australia
    Disabil Rehabil 35:1149-63. 2013
  9. doi Formulations of fentanyl for the management of pain
    Sina Grape
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia
    Drugs 70:57-72. 2010
  10. doi A survey of patients' use of the internet for chronic pain-related information
    Tomas B Corcoran
    School of Medicine and Pharmacology, University of Western Australia, Australia
    Pain Med 11:512-7. 2010

Collaborators

Detail Information

Publications35

  1. ncbi Opioid and non-opioid analgesics
    Stephan A Schug
    Anaesthesia in Pharmacology, University of Western Australia, MRF Building, Royal Perth Hospital, GPO Box X2213, Perth WA 6847, Australia
    Best Pract Res Clin Anaesthesiol 17:91-110. 2003
    ..Toxicity arises primarily from undesired inhibition at these enzyme sites. Knowledge of the mechanism of action of these drugs is fundamental to the understanding of their potential for toxicity, the details of which are still emerging...
  2. pmc The role of tramadol in current treatment strategies for musculoskeletal pain
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia and Department of Anaesthesia and Pain Medicine, Royal Perth Hospital Perth, Western Australia
    Ther Clin Risk Manag 3:717-23. 2007
    ..In conclusion, it is recommended to better implement the more recent guidelines focusing on pain management and consider the role of tramadol in musculoskeletal pain treatment strategies...
  3. ncbi Combination analgesia in 2005 - a rational approach: focus on paracetamol-tramadol
    Stephan A Schug
    School of Medicine and Pharmacology, The University of Western Australia, Level 2, MRF Building G Block Royal Perth Hospital, GPO Box X2213 Perth, WA 6847, Australia
    Clin Rheumatol 25:S16-21. 2006
    ..Hence, paracetamol plus tramadol offers an effective and well-tolerated alternative to anti-inflammatory drugs or other paracetamol plus weak opioid combinations...
  4. ncbi The role of COX-2 inhibitors in the treatment of postoperative pain
    Stephan A Schug
    School of Medicine and Pharmacology, The University of Western Australia, and Royal Perth Hospital, MRF Building at RPH, GPO Box X2213, Perth WA 6847, Australia
    J Cardiovasc Pharmacol 47:S82-6. 2006
    ..Overall, COX-2 inhibitors offer a number of advantages over classical NSAIDs in the postoperative pain setting, but require the same caution with regard to renal effects...
  5. ncbi Update on the role of non-opioids for postoperative pain treatment
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, MRF Building, Royal Perth Hospital, GPO Box X2213, Perth, WA 6847, Australia
    Best Pract Res Clin Anaesthesiol 21:15-30. 2007
    ..Among the anti-inflammatory drugs, selective cyclo-oxygenase-2 inhibitors have the most supportive data for their beneficial effects as a component of multimodal analgesia and offer benefits with regard to their adverse effect profile...
  6. ncbi Neuraxial drug administration: a review of treatment options for anaesthesia and analgesia
    Stephan A Schug
    Pharmacology Unit, School of Medicine and Pharmacology, UWA Anaesthesia, University of Western Australia, Perth, WA, Australia
    CNS Drugs 20:917-33. 2006
    ..The latter is possibly the most unusual compound here; it has recently gained registration for intrathecal use in specific chronic pain conditions...
  7. doi Predictors of patient satisfaction with pain management and improvement 3 months after burn injury
    Rachel M Andrews
    McComb Research Foundation, Western Australia, Australia
    J Burn Care Res 33:442-52. 2012
    ..Very little is known about what influences patient satisfaction with burn pain management. The aim of this prospective study was to examine predictors of patient satisfaction with pain management following burn injury...
  8. doi A pilot randomized controlled trial of an early multidisciplinary model to prevent disability following traumatic injury
    Allyson L Browne
    Statewide Trauma Service of Western Australia, Royal Perth Hospital, Western Australia
    Disabil Rehabil 35:1149-63. 2013
    ..This pilot study examined the clinical utility of screening and early multidisciplinary intervention for reducing disability following traumatic injury...
  9. doi Formulations of fentanyl for the management of pain
    Sina Grape
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia
    Drugs 70:57-72. 2010
    ..Overall, the specific pharmacological and physicochemical properties of fentanyl have made this compound highly suitable for novel routes of administration in a range of clinical indications...
  10. doi A survey of patients' use of the internet for chronic pain-related information
    Tomas B Corcoran
    School of Medicine and Pharmacology, University of Western Australia, Australia
    Pain Med 11:512-7. 2010
    ..To investigate the use of the Internet as a pain information seeking tool among a population of patients attending a chronic pain clinic...
  11. doi Screening for harmful alcohol use in Australian trauma settings
    Allyson L Browne
    Statewide Trauma Service of Western Australia, Royal Perth Hospital, Western Australia, Australia
    Injury 44:110-7. 2013
    ....
  12. doi Training general practitioners in remote Western Australia in a method of screening and brief intervention for harmful alcohol use: a pilot study
    Catherine Brennan
    Statewide Trauma Service of Western Australia, Royal Perth Hospital and Princess Margaret Hospital, Perth, Western Australia, Australia
    Aust J Rural Health 21:72-9. 2013
    ..This study piloted a training model for alcohol screening and brief intervention for GPs working in Kalgoorlie-Boulder, a remote Western Australian community facing significant alcohol-related problems...
  13. ncbi Persistent pain outcomes and patient satisfaction with pain management after burn injury
    Allyson L Browne
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, University of Western Australia, Perth, Western Australia
    Clin J Pain 27:136-45. 2011
    ..This study examined the long-term pain and psychological outcomes of burn survivors who were treated at the Burns Service of Western Australia between 1994 and 2005...
  14. doi Pain management after ambulatory surgery
    Stephan A Schug
    School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital, Perth, Australia
    Curr Opin Anaesthesiol 22:738-43. 2009
    ..Poor pain management has been a problem after ambulatory surgery. This review examines the current situation and recent advances in the area...
  15. ncbi Regional anaesthesia and perioperative outcome
    Evangelos Tziavrangos
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia
    Curr Opin Anaesthesiol 19:521-5. 2006
    ....
  16. doi [COX-2 Inhibitors for the management of postoperative pain]
    Stephan A Schug
    Universität von Westaustralien und Director of Pain Medicine at Royal Perth Hospital in Perth, Aus tralien zurzeit als Gastprofessor am Universitätsklinikum Münster
    Anasthesiol Intensivmed Notfallmed Schmerzther 45:56-63. 2010
    ..In parallel, COX-2 Inhibitors do not carry an increased risk of cardiovascular complications and require the same caution with regard to renal effects as NSAIDs...
  17. doi A randomized, double-blind, placebo-controlled trial assessing the impact of dexamphetamine on fatigue in patients with advanced cancer
    Kirsten Anne Auret
    Rural Clinical School of Western Australia, University of Western Australia, Albany, Australia
    J Pain Symptom Manage 37:613-21. 2009
    ..These results suggest that dexamphetamine 20mg daily, although well tolerated, does not significantly improve fatigue or quality of life in patients with advanced cancer, as measured by the selected instruments...
  18. doi A phase I pharmacokinetic and bioavailability study of a sublingual fentanyl wafer in healthy volunteers
    Chin Beng Stephen Lim
    Pharmacy Department, Armadale Health Service, Armadale, Western Australia, Australia
    Anesth Analg 115:554-9. 2012
    ..The principal study objective was to investigate the pharmacokinetic profile of a new sublingual fentanyl wafer and to establish its absolute bioavailability...
  19. doi The effects of neostigmine and glycopyrrolate on skin conductance as a measure of pain
    Thomas Ledowski
    Anaesthesiology Unit, School of Medicine and Pharmacology, The University of Western Australia, Perth, Western Australia, Australia
    Eur J Anaesthesiol 26:777-81. 2009
    ..In this context, the effects of cholinesterase inhibitors and anticholinergic drugs used for the reversal of muscle relaxants were investigated...
  20. ncbi Underutilisation of opioids in elderly patients with chronic pain: approaches to correcting the problem
    Kirsten Auret
    School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
    Drugs Aging 22:641-54. 2005
    ..This more rational and knowledge-based approach to the use of opioids in the management of chronic pain in the elderly population should correct the current problems with underprescribing in this age group...
  21. ncbi The influence of catecholamines on pseudocholinesterase enzymatic activity. Results of a laboratory investigation
    Thomas Ledowski
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Wellington Street Campus, Perth, WA 6000, Australia
    J Clin Monit Comput 20:329-32. 2006
    ..Aim of this laboratory investigation was to determine whether catecholamines have an effect on PCHE activity, as this knowledge could help to define the role of PCHE in the assessment of stress...
  22. doi Low-dose sublingual ketamine does not modulate experimentally induced mechanical hyperalgesia in healthy subjects
    Helen Slater
    School of Physiotherapy, Curtin Health Innovation Research Institute, Curtin University, Perth, Western Australia
    Pain Med 13:1235-46. 2012
    ..This randomized controlled trial (RCT) investigated the effect of the NMDA receptor antagonist ketamine (25 mg sublingually) on modulating experimental muscle pain...
  23. doi Perioperative analgesia in pediatric surgery
    Phil Russell
    Department of Anesthesia and Pain Management, Princess Margaret Hospital for Children, Perth, Australia
    Curr Opin Anaesthesiol 26:420-7. 2013
    ..Poor pain management has continued to be a problem after pediatric surgery. This review examines the current situation and recent advances in the area...
  24. doi The quality of internet-sourced information for patients with chronic pain is poor
    Tomas B Corcoran
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth daggerSchool of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia
    Clin J Pain 25:617-23. 2009
    ..Patients with chronic pain are a subsection of the community who are likely to seek information about their condition, but previously little was known about the quality of information they may encounter during an Internet search...
  25. ncbi Postoperative pain management of the obese patient
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Best Pract Res Clin Anaesthesiol 25:73-81. 2011
    ....
  26. doi Development of a sublingual/oral formulation of ketamine for use in neuropathic pain: Preliminary findings from a three-way randomized, crossover study
    Chui Chong
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia
    Clin Drug Investig 29:317-24. 2009
    ..The objective of the study was to develop a lozenge formulation of ketamine for use in patients with neuropathic pain, and to investigate its storage stability and bioavailability after oral or sublingual administration...
  27. doi Cardiovascular safety of the cyclooxygenase-2 selective inhibitors parecoxib and valdecoxib in the postoperative setting: an analysis of integrated data
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, University of Western Australia, Perth, Australia
    Anesth Analg 108:299-307. 2009
    ..We conducted this study to address whether parecoxib and valdecoxib increased CV risk in noncardiac surgery patients...
  28. doi Effectiveness of a topical local anaesthetic spray as analgesia for dressing changes: a double-blinded randomised pilot trial comparing an emulsion with an aqueous lidocaine formulation
    Chiragkumar Desai
    School of Pharmacy, Curtin Health Innovation Research Institute, Curtin University of Technology, Perth, Western Australia, Australia N S Technologies Pty Ltd, Perth, WA 6050, Australia Electronic address
    Burns 40:106-12. 2014
    ..This study compared the effectiveness of two different formulations of topical local anaesthetic for dressing changes of partial thickness skin graft donor sites...
  29. ncbi Impact of epidural analgesia on mortality and morbidity after surgery: systematic review and meta-analysis of randomized controlled trials
    Daniel M Pöpping
    Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Munster, Germany Faculty of Medicine, Institute of Social and Preventive Medicine, University of Geneva, Switzerland Department of Anesthesia and Intensive Care, Tenon University Hospital, Assistance Publique Hopitaux de Paris, France Anesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, Australia Department of Anesthesia and Critical Care, University Hospital of Wurzburg, Germany Division of Anesthesiology, Geneva University Hospitals, and Faculty of Medicine, University of Geneva, Switzerland
    Ann Surg 259:1056-67. 2014
    ..To quantify benefit and harm of epidural analgesia, compared with systemic opioid analgesia, in adults having surgery under general anesthesia...
  30. doi Perioperative pain management after thoracotomy
    Manuel Wenk
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, and Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Curr Opin Anaesthesiol 24:8-12. 2011
    ..This review examines and highlights recent strategies and advances in perioperative pain management in this field...
  31. ncbi Bronchial mucus transport velocity in patients receiving propofol and remifentanil versus sevoflurane and remifentanil anesthesia
    Thomas Ledowski
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Australia
    Anesth Analg 102:1427-30. 2006
    ..This could have implications for perioperative pulmonary complications, in particular in patients at risk for pulmonary complications...
  32. ncbi A systematic review of randomized trials evaluating regional techniques for postthoracotomy analgesia
    Girish P Joshi
    Department of Anesthesiology and Pain Management, University of TX Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9068, USA
    Anesth Analg 107:1026-40. 2008
    ....
  33. ncbi Tramadol has a better potency ratio relative to morphine in neuropathic than in nociceptive pain models
    Thomas Christoph
    Biomedical Research, Grunenthal GmbH, Aachen, Germany
    Drugs R D 8:51-7. 2007
    ..The effects of tramadol, an atypically acting analgesic with a combined opioid and monoaminergic mechanism of action, and morphine, a prototypical opioid, were tested in rat models of neuropathic and nociceptive pain...
  34. ncbi Acute pain management: the evidence grows
    Pamela E Macintyre
    Med J Aust 184:101-2. 2006
    ..An Australian document now has an important role in acute pain management worldwide...
  35. ncbi Clinical evaluation of onset of analgesia using intravenous pamidronate in metastatic bone pain
    Eugen B Petcu
    J Pain Symptom Manage 24:281-4. 2002