Stephan A Schug

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi request reprint Opioid and non-opioid analgesics
    Stephan A Schug
    Anaesthesia in Pharmacology, University of Western Australia, MRF Building, Royal Perth Hospital, GPO Box X2213, Perth WA 6847, Australia
    Best Pract Res Clin Anaesthesiol 17:91-110. 2003
  2. ncbi request reprint Update on the role of non-opioids for postoperative pain treatment
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, MRF Building, Royal Perth Hospital, GPO Box X2213, Perth, WA 6847, Australia
    Best Pract Res Clin Anaesthesiol 21:15-30. 2007
  3. ncbi request reprint Neuraxial drug administration: a review of treatment options for anaesthesia and analgesia
    Stephan A Schug
    Pharmacology Unit, School of Medicine and Pharmacology, UWA Anaesthesia, University of Western Australia, Perth, WA, Australia
    CNS Drugs 20:917-33. 2006
  4. ncbi request reprint The role of COX-2 inhibitors in the treatment of postoperative pain
    Stephan A Schug
    School of Medicine and Pharmacology, The University of Western Australia, and Royal Perth Hospital, MRF Building at RPH, GPO Box X2213, Perth WA 6847, Australia
    J Cardiovasc Pharmacol 47:S82-6. 2006
  5. ncbi request reprint Combination analgesia in 2005 - a rational approach: focus on paracetamol-tramadol
    Stephan A Schug
    School of Medicine and Pharmacology, The University of Western Australia, Level 2, MRF Building G Block Royal Perth Hospital, GPO Box X2213 Perth, WA 6847, Australia
    Clin Rheumatol 25:S16-21. 2006
  6. doi request reprint Formulations of fentanyl for the management of pain
    Sina Grape
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia
    Drugs 70:57-72. 2010
  7. doi request reprint A survey of patients' use of the internet for chronic pain-related information
    Tomas B Corcoran
    School of Medicine and Pharmacology, University of Western Australia, Australia
    Pain Med 11:512-7. 2010
  8. doi request reprint Pain management after ambulatory surgery
    Stephan A Schug
    School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital, Perth, Australia
    Curr Opin Anaesthesiol 22:738-43. 2009
  9. ncbi request reprint Persistent pain outcomes and patient satisfaction with pain management after burn injury
    Allyson L Browne
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, University of Western Australia, Perth, Western Australia
    Clin J Pain 27:136-45. 2011
  10. doi request reprint Training general practitioners in remote Western Australia in a method of screening and brief intervention for harmful alcohol use: A pilot study
    Catherine Brennan
    Statewide Trauma Service of Western Australia, Royal Perth Hospital and Princess Margaret Hospital, Perth, Western Australia, Australia
    Aust J Rural Health 21:72-9. 2013

Detail Information

Publications27

  1. ncbi request reprint Opioid and non-opioid analgesics
    Stephan A Schug
    Anaesthesia in Pharmacology, University of Western Australia, MRF Building, Royal Perth Hospital, GPO Box X2213, Perth WA 6847, Australia
    Best Pract Res Clin Anaesthesiol 17:91-110. 2003
    ..Toxicity arises primarily from undesired inhibition at these enzyme sites. Knowledge of the mechanism of action of these drugs is fundamental to the understanding of their potential for toxicity, the details of which are still emerging...
  2. ncbi request reprint Update on the role of non-opioids for postoperative pain treatment
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, MRF Building, Royal Perth Hospital, GPO Box X2213, Perth, WA 6847, Australia
    Best Pract Res Clin Anaesthesiol 21:15-30. 2007
    ..Among the anti-inflammatory drugs, selective cyclo-oxygenase-2 inhibitors have the most supportive data for their beneficial effects as a component of multimodal analgesia and offer benefits with regard to their adverse effect profile...
  3. ncbi request reprint Neuraxial drug administration: a review of treatment options for anaesthesia and analgesia
    Stephan A Schug
    Pharmacology Unit, School of Medicine and Pharmacology, UWA Anaesthesia, University of Western Australia, Perth, WA, Australia
    CNS Drugs 20:917-33. 2006
    ..The latter is possibly the most unusual compound here; it has recently gained registration for intrathecal use in specific chronic pain conditions...
  4. ncbi request reprint The role of COX-2 inhibitors in the treatment of postoperative pain
    Stephan A Schug
    School of Medicine and Pharmacology, The University of Western Australia, and Royal Perth Hospital, MRF Building at RPH, GPO Box X2213, Perth WA 6847, Australia
    J Cardiovasc Pharmacol 47:S82-6. 2006
    ..Overall, COX-2 inhibitors offer a number of advantages over classical NSAIDs in the postoperative pain setting, but require the same caution with regard to renal effects...
  5. ncbi request reprint Combination analgesia in 2005 - a rational approach: focus on paracetamol-tramadol
    Stephan A Schug
    School of Medicine and Pharmacology, The University of Western Australia, Level 2, MRF Building G Block Royal Perth Hospital, GPO Box X2213 Perth, WA 6847, Australia
    Clin Rheumatol 25:S16-21. 2006
    ..Hence, paracetamol plus tramadol offers an effective and well-tolerated alternative to anti-inflammatory drugs or other paracetamol plus weak opioid combinations...
  6. doi request reprint Formulations of fentanyl for the management of pain
    Sina Grape
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia
    Drugs 70:57-72. 2010
    ..Overall, the specific pharmacological and physicochemical properties of fentanyl have made this compound highly suitable for novel routes of administration in a range of clinical indications...
  7. doi request reprint A survey of patients' use of the internet for chronic pain-related information
    Tomas B Corcoran
    School of Medicine and Pharmacology, University of Western Australia, Australia
    Pain Med 11:512-7. 2010
    ..To investigate the use of the Internet as a pain information seeking tool among a population of patients attending a chronic pain clinic...
  8. doi request reprint Pain management after ambulatory surgery
    Stephan A Schug
    School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital, Perth, Australia
    Curr Opin Anaesthesiol 22:738-43. 2009
    ..Poor pain management has been a problem after ambulatory surgery. This review examines the current situation and recent advances in the area...
  9. ncbi request reprint Persistent pain outcomes and patient satisfaction with pain management after burn injury
    Allyson L Browne
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, University of Western Australia, Perth, Western Australia
    Clin J Pain 27:136-45. 2011
    ..This study examined the long-term pain and psychological outcomes of burn survivors who were treated at the Burns Service of Western Australia between 1994 and 2005...
  10. doi request reprint Training general practitioners in remote Western Australia in a method of screening and brief intervention for harmful alcohol use: A pilot study
    Catherine Brennan
    Statewide Trauma Service of Western Australia, Royal Perth Hospital and Princess Margaret Hospital, Perth, Western Australia, Australia
    Aust J Rural Health 21:72-9. 2013
    ..This study piloted a training model for alcohol screening and brief intervention for GPs working in Kalgoorlie-Boulder, a remote Western Australian community facing significant alcohol-related problems...
  11. ncbi request reprint Regional anaesthesia and perioperative outcome
    Evangelos Tziavrangos
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia
    Curr Opin Anaesthesiol 19:521-5. 2006
    ....
  12. doi request reprint [COX-2 Inhibitors for the management of postoperative pain]
    Stephan A Schug
    Universität von Westaustralien und Director of Pain Medicine at Royal Perth Hospital in Perth, Aus tralien zurzeit als Gastprofessor am Universitätsklinikum Münster
    Anasthesiol Intensivmed Notfallmed Schmerzther 45:56-63. 2010
    ..In parallel, COX-2 Inhibitors do not carry an increased risk of cardiovascular complications and require the same caution with regard to renal effects as NSAIDs...
  13. doi request reprint A randomized, double-blind, placebo-controlled trial assessing the impact of dexamphetamine on fatigue in patients with advanced cancer
    Kirsten Anne Auret
    Rural Clinical School of Western Australia, University of Western Australia, Albany, Australia
    J Pain Symptom Manage 37:613-21. 2009
    ..These results suggest that dexamphetamine 20mg daily, although well tolerated, does not significantly improve fatigue or quality of life in patients with advanced cancer, as measured by the selected instruments...
  14. doi request reprint Screening for harmful alcohol use in Australian trauma settings
    Allyson L Browne
    Statewide Trauma Service of Western Australia, Royal Perth Hospital, Western Australia, Australia
    Injury 44:110-7. 2013
    ....
  15. ncbi request reprint The influence of catecholamines on pseudocholinesterase enzymatic activity. Results of a laboratory investigation
    Thomas Ledowski
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Wellington Street Campus, Perth, WA 6000, Australia
    J Clin Monit Comput 20:329-32. 2006
    ..Aim of this laboratory investigation was to determine whether catecholamines have an effect on PCHE activity, as this knowledge could help to define the role of PCHE in the assessment of stress...
  16. doi request reprint The effects of neostigmine and glycopyrrolate on skin conductance as a measure of pain
    Thomas Ledowski
    Anaesthesiology Unit, School of Medicine and Pharmacology, The University of Western Australia, Perth, Western Australia, Australia
    Eur J Anaesthesiol 26:777-81. 2009
    ..In this context, the effects of cholinesterase inhibitors and anticholinergic drugs used for the reversal of muscle relaxants were investigated...
  17. ncbi request reprint Underutilisation of opioids in elderly patients with chronic pain: approaches to correcting the problem
    Kirsten Auret
    School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
    Drugs Aging 22:641-54. 2005
    ..This more rational and knowledge-based approach to the use of opioids in the management of chronic pain in the elderly population should correct the current problems with underprescribing in this age group...
  18. doi request reprint Cardiovascular safety of the cyclooxygenase-2 selective inhibitors parecoxib and valdecoxib in the postoperative setting: an analysis of integrated data
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, University of Western Australia, Perth, Australia
    Anesth Analg 108:299-307. 2009
    ..We conducted this study to address whether parecoxib and valdecoxib increased CV risk in noncardiac surgery patients...
  19. doi request reprint Development of a sublingual/oral formulation of ketamine for use in neuropathic pain: Preliminary findings from a three-way randomized, crossover study
    Chui Chong
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia
    Clin Drug Investig 29:317-24. 2009
    ..The objective of the study was to develop a lozenge formulation of ketamine for use in patients with neuropathic pain, and to investigate its storage stability and bioavailability after oral or sublingual administration...
  20. doi request reprint The quality of internet-sourced information for patients with chronic pain is poor
    Tomas B Corcoran
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth daggerSchool of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia
    Clin J Pain 25:617-23. 2009
    ..Patients with chronic pain are a subsection of the community who are likely to seek information about their condition, but previously little was known about the quality of information they may encounter during an Internet search...
  21. ncbi request reprint Postoperative pain management of the obese patient
    Stephan A Schug
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Best Pract Res Clin Anaesthesiol 25:73-81. 2011
    ....
  22. ncbi request reprint Bronchial mucus transport velocity in patients receiving propofol and remifentanil versus sevoflurane and remifentanil anesthesia
    Thomas Ledowski
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Australia
    Anesth Analg 102:1427-30. 2006
    ..This could have implications for perioperative pulmonary complications, in particular in patients at risk for pulmonary complications...
  23. doi request reprint Perioperative pain management after thoracotomy
    Manuel Wenk
    Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, and Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Curr Opin Anaesthesiol 24:8-12. 2011
    ..This review examines and highlights recent strategies and advances in perioperative pain management in this field...
  24. doi request reprint A systematic review of randomized trials evaluating regional techniques for postthoracotomy analgesia
    Girish P Joshi
    Department of Anesthesiology and Pain Management, University of TX Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9068, USA
    Anesth Analg 107:1026-40. 2008
    ....
  25. ncbi request reprint Tramadol has a better potency ratio relative to morphine in neuropathic than in nociceptive pain models
    Thomas Christoph
    Biomedical Research, Grunenthal GmbH, Aachen, Germany
    Drugs R D 8:51-7. 2007
    ..The effects of tramadol, an atypically acting analgesic with a combined opioid and monoaminergic mechanism of action, and morphine, a prototypical opioid, were tested in rat models of neuropathic and nociceptive pain...
  26. ncbi request reprint Acute pain management: the evidence grows
    Pamela E Macintyre
    Med J Aust 184:101-2. 2006
    ..An Australian document now has an important role in acute pain management worldwide...
  27. ncbi request reprint Clinical evaluation of onset of analgesia using intravenous pamidronate in metastatic bone pain
    Eugen B Petcu
    J Pain Symptom Manage 24:281-4. 2002