Sarah C Sasson

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi Increased plasma interleukin-7 level correlates with decreased CD127 and Increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection
    Sarah C Sasson
    National Centre in HIV Epidemiology and Clinical Research, Sydney, Australia
    J Infect Dis 193:505-14. 2006
  2. ncbi The IL-7/IL-7 receptor axis: understanding its central role in T-cell homeostasis and the challenges facing its utilization as a novel therapy
    Sarah C Sasson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    Curr Drug Targets 7:1571-82. 2006
  3. doi IL-7 receptor is expressed on adult pre-B-cell acute lymphoblastic leukemia and other B-cell derived neoplasms and correlates with expression of proliferation and survival markers
    Sarah C Sasson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    Cytokine 50:58-68. 2010
  4. pmc Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection
    Sarah C Sasson
    The Kirby Institute, The University of New South Wales, Sydney, Australia
    PLoS ONE 7:e31148. 2012
  5. pmc Infection of CD127+ (interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection
    John J Zaunders
    Centre for Immunology, St Vincent s Hospital, Victoria Street, Darlinghurst, NSW 2010, Australia
    J Virol 80:10162-72. 2006
  6. doi Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease
    Nabila Seddiki
    Centre for Immunology, St Vincent s Hospital, Darlinghurst, NSW, Australia
    Eur J Immunol 39:391-403. 2009
  7. pmc Posterior reversible encephalopathy syndrome (PRES) in an HIV-1 infected patient with disseminated varicella zoster virus: a case report
    Sarah C Sasson
    HIV, Immunology and Infectious Diseases Unit, St Vincent s Hospital, 390 Victoria Street Darlinghurst, 2010, Sydney, NSW, Australia
    BMC Infect Dis 13:396. 2013
  8. ncbi The modern ART of HIV infection management: towards a tailored approach to maximize CD4 T cell reconstitution
    Sarah C Sasson
    Clin Infect Dis 41:373-5. 2005

Detail Information

Publications8

  1. ncbi Increased plasma interleukin-7 level correlates with decreased CD127 and Increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection
    Sarah C Sasson
    National Centre in HIV Epidemiology and Clinical Research, Sydney, Australia
    J Infect Dis 193:505-14. 2006
    ....
  2. ncbi The IL-7/IL-7 receptor axis: understanding its central role in T-cell homeostasis and the challenges facing its utilization as a novel therapy
    Sarah C Sasson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    Curr Drug Targets 7:1571-82. 2006
    ..Ultimately this understanding may lead to therapeutics that manipulate and optimise signalling through the IL-7/IL-7R system...
  3. doi IL-7 receptor is expressed on adult pre-B-cell acute lymphoblastic leukemia and other B-cell derived neoplasms and correlates with expression of proliferation and survival markers
    Sarah C Sasson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    Cytokine 50:58-68. 2010
    ..Patients with B-cell derived neoplasms had elevated circulating IL-10 and decreased BAFF. These findings support a role for the IL-7/IL-7R system in B-cell oncogenesis...
  4. pmc Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection
    Sarah C Sasson
    The Kirby Institute, The University of New South Wales, Sydney, Australia
    PLoS ONE 7:e31148. 2012
    ..We investigated the correlates of loss of CD127 from the T-cell surface to understand mechanisms underlying this homeostatic dysregulation...
  5. pmc Infection of CD127+ (interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection
    John J Zaunders
    Centre for Immunology, St Vincent s Hospital, Victoria Street, Darlinghurst, NSW 2010, Australia
    J Virol 80:10162-72. 2006
    ..Taken together, the loss of HIV-specific CD4+ T cells is associated with a combination of an infection of CCR5+ CD127+ memory CD4+ T cells, possibly in GALT, and a high expression of the inhibitory receptor CTLA-4...
  6. doi Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease
    Nabila Seddiki
    Centre for Immunology, St Vincent s Hospital, Darlinghurst, NSW, Australia
    Eur J Immunol 39:391-403. 2009
    ..These data suggest that despite substantial Treg expansion in IRD, their ability to induce suppression, and thereby downregulate aberrant immune responses, is compromised...
  7. pmc Posterior reversible encephalopathy syndrome (PRES) in an HIV-1 infected patient with disseminated varicella zoster virus: a case report
    Sarah C Sasson
    HIV, Immunology and Infectious Diseases Unit, St Vincent s Hospital, 390 Victoria Street Darlinghurst, 2010, Sydney, NSW, Australia
    BMC Infect Dis 13:396. 2013
    ....
  8. ncbi The modern ART of HIV infection management: towards a tailored approach to maximize CD4 T cell reconstitution
    Sarah C Sasson
    Clin Infect Dis 41:373-5. 2005