Research Topics
| Jerome SarrisSummaryAffiliation: University of Queensland Country: Australia Publications
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Detail Information
Publications
Kava and St. John's Wort: current evidence for use in mood and anxiety disordersJerome Sarris
School of Medicine, The University of Queensland, Royal Brisbane and Women s Hospital, Queensland, Brisbane, Australia
J Altern Complement Med 15:827-36. 2009..Mood and anxiety disorders pose significant health burdens on the community. Kava and St. John's wort (SJW) are the most commonly used herbal medicines in the treatment of anxiety and depressive disorders, respectively...- Re-introduction of kava (Piper methysticum) to the EU: is there a way forward?Jerome Sarris
Department of Psychiatry, Faculty of Medicine, The University of Melbourne, Melbourne, Australia
Planta Med 77:107-10. 2011..The results of the study may be of benefit to sufferers of anxiety and the future economy of the Pacific islands, potentially providing an important step in the way forward with kava... - St. John's wort and Kava in treating major depressive disorder with comorbid anxiety: a randomised double-blind placebo-controlled pilot trialJerome Sarris
School of Medicine, The University of Queensland, Australia
Hum Psychopharmacol 24:41-8. 2009..We report the first randomised controlled trial (RCT) using a combination of St. John's wort (SJW) and Kava for the treatment of major depressive disorder (MDD) with comorbid anxiety... - Major depressive disorder and nutritional medicine: a review of monotherapies and adjuvant treatmentsJerome Sarris
School of Medicine, The University of Queensland, Herston Road, Herston 4006, Brisbane, Australia
Nutr Rev 67:125-31. 2009..Inositol lacks evidence as an effective antidepressant and cannot be currently recommended. Evidence on the use of L-tryptophan for depression is inconclusive, and additional studies utilizing a more robust methodology are required... - Kava Anxiety Depression Spectrum Study (KADSS): a mixed methods RCT using an aqueous extract of Piper methysticumJ Sarris
School of Medicine, University of Queensland, Australia
Complement Ther Med 17:176-8. 2009..The Kava Anxiety Depression Spectrum Study (KADSS) is a 3-week placebo-controlled, double-blind, cross-over trial involving 60 adult participants (18-65) with elevated stable anxiety and varying levels of depressive symptoms... - The Kava Anxiety Depression Spectrum Study (KADSS): a randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticumJ Sarris
School of Medicine, The University of Queensland, Brisbane, Australia
Psychopharmacology (Berl) 205:399-407. 2009..Piper methysticum (Kava) has been withdrawn in European, British, and Canadian markets due to concerns over hepatotoxic reactions. The WHO recently recommended research into "aqueous" extracts of Kava... - Adjuvant use of nutritional and herbal medicines with antidepressants, mood stabilizers and benzodiazepinesJerome Sarris
School of Medicine, University of Queensland, Queensland, Australia
J Psychiatr Res 44:32-41. 2010..This remains a promising area of research via robust, safety-conscious studies... - Complementary medicine use by middle-aged and older women: personality, mood and anxiety factorsJ Sarris
University of Queensland, Australia
J Health Psychol 16:314-21. 2011..Regression models revealed that number of specialists' consultations, number of CAM products used and reported level of physical and leisure activities were predictive of CAM therapy use; while age was predictive of CAM product use... - Comparative use of complementary medicine, allied health, and manual therapies by middle-aged and older Australian womenJerome Sarris
School of Medicine, The University of Queensland, Brisbane, Australia
J Women Aging 22:273-82. 2010..In contrast, there was a highly significant difference between the overall use of CAM products by middle-aged women (88.2%) and older women (67.7%: p = .002)... - Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidenceJerome Sarris
The University of Melbourne, Department of Psychiatry, Australia
Eur Neuropsychopharmacol 21:841-60. 2011..Several herbal medicines with in vitro and in vivo evidence are currently unexplored in human studies, and along with use of emerging genetic technologies "herbomics", are areas of potential future research... 
Clinical depression: an evidence-based integrative complementary medicine treatment modelJerome Sarris
The University of Melbourne, Faculty of Medicine, Department of Psychiatry, Australia
Altern Ther Health Med 17:26-37. 2011..In practice, clinicians often use a variety of interventions; however, this approach may not be systematic, and many interventions used may not be based on strong evidence...
Kava hepatotoxicity in traditional and modern use: the presumed Pacific kava paradox hypothesis revisitedRolf Teschke
Department of Internal Medicine II, Division of Gastroenterology and Hepatology, Klinikum Hanau, Teaching Hospital of the Goethe University of Frankfurt Main, Hanau, Germany
Br J Clin Pharmacol 73:170-4. 2012..Rigorous testing of kava raw material is urgently advised, in addition to Pan-Pacific kava manufacturing quality standards...- Bipolar disorder and complementary medicine: current evidence, safety issues, and clinical considerationsJerome Sarris
Department of Psychiatry, Faculty of Medicine, The University of Melbourne, The Melbourne Clinic, Melbourne, Victoria, Australia
J Altern Complement Med 17:881-90. 2011..To date, no review has focused specifically on nonconventional treatments of BD... - Kava: a comprehensive review of efficacy, safety, and psychopharmacologyJerome Sarris
Department of Psychiatry, The Melbourne Clinic, The University of Melbourne, Victoria, Australia
Aust N Z J Psychiatry 45:27-35. 2011..Kava is available over the counter in jurisdictions such as the USA, Australia and New Zealand. Due to this, a review of efficacy, safety and clinical recommendations is advised... - 'Omic' genetic technologies for herbal medicines in psychiatryJerome Sarris
Professorial Unit, The Melbourne Clinic, Department of Psychiatry, University of Melbourne, Australia
Phytother Res 26:522-7. 2012..This paper focuses on the emerging field of herbomics, and is to our knowledge the first publication to explore this in the area of psychiatry... - Adjunctive nutraceuticals with standard pharmacotherapies in bipolar disorder: a systematic review of clinical trialsJerome Sarris
Department of Psychiatry, Faculty of Medicine, University of Melbourne, The Melbourne Clinic2 Salisbury Street, Richmond, Victoria 3121, Australia
Bipolar Disord 13:454-65. 2011..A subsequent aim of this report was to discuss posited underlying mechanisms of action... - Do long-chain n-3 fatty acids reduce arterial stiffness? A meta-analysis of randomised controlled trialsMatthew P Pase
NICM Centre for Study of Natural Medicines and Neurocognition, Melbourne, Australia
Br J Nutr 106:974-80. 2011..Reduction in arterial stiffness by n-3 may account for some of its purported cardioprotective effects... - A systematic review of insomnia and complementary medicineJerome Sarris
Department of Psychiatry, Faculty of Medicine, The University of Melbourne, Melbourne, Victoria, Australia
Sleep Med Rev 15:99-106. 2011..RCTs evaluating other untested CAM therapies such as massage, homoeopathy, or osteopathy are encouraged, as is the exploration of using CAM therapies adjuvantly with conventional therapies... - Participant experiences from chronic administration of a multivitamin versus placebo on subjective health and wellbeing: a double-blind qualitative analysis of a randomised controlled trialJerome Sarris
Department of Psychiatry, The University of Melbourne, Melbourne, Australia
Nutr J 11:110. 2012..While many randomised controlled trials have been conducted on multivitamins, to our knowledge no qualitative research exploring the subjective experience of taking a multivitamin during a clinical trial has been reported... - Complementary medicine, self-help, and lifestyle interventions for obsessive compulsive disorder (OCD) and the OCD spectrum: a systematic reviewJerome Sarris
The University of Melbourne, Faculty of Medicine, Department of Psychiatry, Richmond, Victoria, Australia
J Affect Disord 138:213-21. 2012.... - Omega-3 for bipolar disorder: meta-analyses of use in mania and bipolar depressionJerome Sarris
Department of Psychiatry, Faculty of Medicine, The University of Melbourne, Richmond, Victoria, Australia
J Clin Psychiatry 73:81-6. 2012..Thus, we present the significant findings from meta-analyses of omega-3 in the treatment of bipolar depression and bipolar mania... - Complementary medicines (herbal and nutritional products) in the treatment of Attention Deficit Hyperactivity Disorder (ADHD): a systematic review of the evidenceJerome Sarris
The University of Melbourne, Department of Psychiatry, Australia
Complement Ther Med 19:216-27. 2011..In such vulnerable populations high quality evidence is required to support such claims... - Nutraceuticals in the treatment of obsessive compulsive disorder (OCD): a review of mechanistic and clinical evidenceDavid A Camfield
National Institute of Complementary Medicine Collaborative Centre for Neurocognition, Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
Prog Neuropsychopharmacol Biol Psychiatry 35:887-95. 2011..It is recommended that future clinical trials of nutraceutical treatments for OCD utilize randomized placebo-controlled study designs and considerably larger sample sizes in order to properly test for efficacy... - Herbal medicines in the treatment of psychiatric disorders: a systematic reviewJerome Sarris
School of Medicine, Department of Psychiatry, University of Queensland, Brisbane, Australia
Phytother Res 21:703-16. 2007..Particular attention is given to clinical and safety issues with St John's wort and kava... - Plant-based medicines for anxiety disorders, Part 1: a review of preclinical studiesJerome Sarris
Department of Psychiatry, Faculty of Medicine, University of Melbourne, 2 Salisbury Street, Richmond, Vic, 3121, Australia
CNS Drugs 27:207-19. 2013..Future research should focus on conducting human clinical trials on the plants reviewed with promising anxiolytic activity... - Current challenges in appraising complementary medicine evidenceJerome Sarris
Department of Psychiatry, University of Melbourne, Melbourne, Australia
Med J Aust 196:310-1. 2012..In addition, providing intellectual property protection to CAM companies may encourage greater investment in research; however, more accountability of study results is critical... - The effects of dietary and nutrient interventions on arterial stiffness: a systematic reviewMatthew P Pase
National Institute of Complementary Medicine Centre for Study of Natural Medicines and Neurocognition, Melbourne, Australia
Am J Clin Nutr 93:446-54. 2011..Although dietary and nutrient interventions have been extensively studied as a means of improving arterial stiffness, to our knowledge no systematic analysis of the data has been conducted...