Gopala Rangan

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi request reprint Dietary quercetin augments activator protein-1 and does not reduce nuclear factor-kappa B in the renal cortex of rats with established chronic glomerular disease
    Gopala K Rangan
    Department of Renal Medicine, University of Sydney at Westmead Hospital, Westmead, Sydney, Australia
    Nephron 90:313-9. 2002
  2. ncbi request reprint Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy
    Jason D Coombes
    Kidney Regeneration Laboratory, Centre for Transplant and Renal Research, The University of Sydney, Westmead Hospital, Sydney, Australia
    Kidney Int 68:2599-607. 2005
  3. ncbi request reprint Quantification of renal pathology by image analysis
    Gopala K Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney, Sydney, New South Wales, Australia
    Nephrology (Carlton) 12:553-8. 2007
  4. ncbi request reprint Therapeutic role of sirolimus in non-transplant kidney disease
    Gopala K Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, Westmead Hospital, Sydney, Australia
    Pharmacol Ther 123:187-206. 2009
  5. ncbi request reprint C5b-9 regulates peritubular myofibroblast accumulation in experimental focal segmental glomerulosclerosis
    Gopala K Rangan
    Division of Nephrology, University of Washington Medical Center, Seattle, Washington, USA
    Kidney Int 66:1838-48. 2004
  6. ncbi request reprint C5b-9 does not mediate chronic tubulointerstitial disease in the absence of proteinuria
    Gopala K Rangan
    Division of Nephrology, University of Washington Medical Center, Seattle, Washington, USA
    Kidney Int 67:492-503. 2005
  7. ncbi request reprint NF-kappaB signalling in chronic kidney disease
    Gopala Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, Westmead Hospital and Sydney West Area Health Service, Sydney, Australia
    Front Biosci (Landmark Ed) 14:3496-522. 2009
  8. ncbi request reprint Sirolimus-associated proteinuria and renal dysfunction
    Gopala K Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney at Westmead Hospital, Sydney, New South Wales, Australia
    Drug Saf 29:1153-61. 2006
  9. ncbi request reprint Effect of nephrotoxins on tubulointerstitial injury and NF-kappaB activation in Adriamycin nephropathy
    Gopala K Rangan
    Department of Renal Medicine and Transplantation, Center for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney, Westmead Hospital, Westmead, Sydney 2145, Australia
    Ren Fail 27:609-14. 2005
  10. ncbi request reprint Renoprotective effects of sirolimus in non-immune initiated focal segmental glomerulosclerosis
    Gopala K Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney at Westmead Hospital, Westmead NSW 2145, Sydney, Australia 2145
    Nephrol Dial Transplant 22:2175-82. 2007

Detail Information

Publications20

  1. ncbi request reprint Dietary quercetin augments activator protein-1 and does not reduce nuclear factor-kappa B in the renal cortex of rats with established chronic glomerular disease
    Gopala K Rangan
    Department of Renal Medicine, University of Sydney at Westmead Hospital, Westmead, Sydney, Australia
    Nephron 90:313-9. 2002
    ..Here we investigated the efficacy of quercetin to suppress renal cortical NF-kappa B/AP-1 activation and tubulointerstitial injury, in vivo, in a nephrotic rat model of chronic glomerular disease...
  2. ncbi request reprint Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy
    Jason D Coombes
    Kidney Regeneration Laboratory, Centre for Transplant and Renal Research, The University of Sydney, Westmead Hospital, Sydney, Australia
    Kidney Int 68:2599-607. 2005
    ..This study investigated the effects of rapamycin on renal function and structure in protein overload nephropathy...
  3. ncbi request reprint Quantification of renal pathology by image analysis
    Gopala K Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney, Sydney, New South Wales, Australia
    Nephrology (Carlton) 12:553-8. 2007
    ....
  4. ncbi request reprint Therapeutic role of sirolimus in non-transplant kidney disease
    Gopala K Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, Westmead Hospital, Sydney, Australia
    Pharmacol Ther 123:187-206. 2009
    ..Therefore, at present, polycystic kidney disease is the most promising therapeutic application for sirolimus in non-transplant renal diseases, and further studies are needed to clarify its role in other situations...
  5. ncbi request reprint C5b-9 regulates peritubular myofibroblast accumulation in experimental focal segmental glomerulosclerosis
    Gopala K Rangan
    Division of Nephrology, University of Washington Medical Center, Seattle, Washington, USA
    Kidney Int 66:1838-48. 2004
    ..Here, we hypothesized that C5b-9 formation regulates renal myofibroblast accumulation in Adriamycin nephropathy...
  6. ncbi request reprint C5b-9 does not mediate chronic tubulointerstitial disease in the absence of proteinuria
    Gopala K Rangan
    Division of Nephrology, University of Washington Medical Center, Seattle, Washington, USA
    Kidney Int 67:492-503. 2005
    ..Here, we examined whether C5b-9 has a pathogenic role in tubulointerstitial disease in the absence of proteinuria...
  7. ncbi request reprint NF-kappaB signalling in chronic kidney disease
    Gopala Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, Westmead Hospital and Sydney West Area Health Service, Sydney, Australia
    Front Biosci (Landmark Ed) 14:3496-522. 2009
    ..This review will examine current evidence regarding NF- kappaB isoforms and their potential role in the treatment of kidney failure due to CKD...
  8. ncbi request reprint Sirolimus-associated proteinuria and renal dysfunction
    Gopala K Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney at Westmead Hospital, Sydney, New South Wales, Australia
    Drug Saf 29:1153-61. 2006
    ..Further long-term analysis of renal allograft studies using sirolimus as de novo immunosuppression along with clinical and laboratory studies will refine these issues in the future...
  9. ncbi request reprint Effect of nephrotoxins on tubulointerstitial injury and NF-kappaB activation in Adriamycin nephropathy
    Gopala K Rangan
    Department of Renal Medicine and Transplantation, Center for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney, Westmead Hospital, Westmead, Sydney 2145, Australia
    Ren Fail 27:609-14. 2005
    ....
  10. ncbi request reprint Renoprotective effects of sirolimus in non-immune initiated focal segmental glomerulosclerosis
    Gopala K Rangan
    Centre for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney at Westmead Hospital, Westmead NSW 2145, Sydney, Australia 2145
    Nephrol Dial Transplant 22:2175-82. 2007
    ....
  11. ncbi request reprint Adriamycin nephropathy in severe combined immunodeficient (SCID) mice
    Vincent W S Lee
    Centre for Transplantation and Renal Research, the University of Sydney at Westmead Millennium Institute and Centre for Kidney Research, The Children s Hospital at Westmead, Sydney, Australia
    Nephrol Dial Transplant 21:3293-8. 2006
  12. ncbi request reprint DNA vaccination with CCL2 DNA modified by the addition of an adjuvant epitope protects against "nonimmune" toxic renal injury
    Guoping Zheng
    Centre for Transplantation and Renal Research, University of Sydney at Westmead Millenium Institute, Westmead, Sydney, NSW 2145 Australia
    J Am Soc Nephrol 17:465-74. 2006
    ....
  13. ncbi request reprint Acute interstitial nephritis secondary to esomeprazole
    Nimeshan Geevasinga
    Clinical School, Westmead Hospital, PO Box 533, Wentworthville, NSW 2145, Australia
    Med J Aust 182:235-6. 2005
  14. pmc Disruption of E-cadherin by matrix metalloproteinase directly mediates epithelial-mesenchymal transition downstream of transforming growth factor-beta1 in renal tubular epithelial cells
    Guoping Zheng
    Centre for Transplantation and Renal Research, The University of Sydney at Westmead Millennium Institute, Westmead, NSW 2145 Australia
    Am J Pathol 175:580-91. 2009
    ..Specific inhibition rather than activation of matrix metalloproteinases may offer a novel approach for treatment of fibrotic disease...
  15. ncbi request reprint Partial depletion of macrophages by ED7 reduces renal injury in Adriamycin nephropathy
    Yiping Wang
    Department of Renal Medicine, The University of Sydney at Westmead Hospital, Westmead, Sydney, New South Wales, Australia
    Nephrology (Carlton) 10:470-7. 2005
    ..In the present study, a monoclonal antibody (ED7) directed against CD11b/CD18 integrin, which is expressed by macrophages, was used to investigate the pathogenetic effects of macrophages in ADR nephropathy...
  16. ncbi request reprint Can murine diabetic nephropathy be separated from superimposed acute renal failure?
    Yuet Ching Tay
    Centre for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney at Westmead Hospital, Westmead, Sydney, Australia
    Kidney Int 68:391-8. 2005
    ....
  17. ncbi request reprint Sirolimus does not reduce receptor-mediated endocytosis of albumin in proximal tubule cells
    Ellein Mreich
    Transplantation 83:105-7. 2007
  18. ncbi request reprint A blast from the mast?
    Gopala K Rangan
    Kidney Int 64:1134-5. 2003
  19. ncbi request reprint Altered expression of nuclear factor-kappaB in peripheral blood mononuclear cells in chronic haemodialysis patients
    Gopala K Rangan
    Nephrol Dial Transplant 21:1137-9. 2006
  20. ncbi request reprint Temporal relationship between renal cyst development, hypertension and cardiac hypertrophy in a new rat model of autosomal recessive polycystic kidney disease
    Jacqueline K Phillips
    Division of Health Sciences, School of Veterinary and Biomedical Science, Murdoch University, Perth, Australia
    Kidney Blood Press Res 30:129-44. 2007
    ....