R L Prince

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi Short and medium-term effects of an education self-management program for individuals with osteoarthritis of the knee, designed and delivered by health professionals: a quality assurance study
    Sophie Coleman
    Arthritis Foundation of Western Australia, PO Box 34, Wembley, Western Australia, 6913, Australia
    BMC Musculoskelet Disord 9:117. 2008
  2. ncbi Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women
    Richard L Prince
    School of Medicine and Pharmacology, Univerity of Western Australia, Perth, Australia
    Arch Intern Med 168:103-8. 2008
  3. ncbi The clinical utility of measured kyphosis as a predictor of the presence of vertebral deformities
    R L Prince
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Osteoporos Int 18:621-7. 2007
  4. ncbi Calcium and vitamin D--for whom and when
    Richard L Prince
    School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Perth, WA 6009, Australia
    Menopause Int 13:35-7. 2007
  5. ncbi Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women
    Richard L Prince
    School of Medicine and Pharmacology, University of Western Australia, Australia
    Arch Intern Med 166:869-75. 2006
  6. ncbi 8: Disorders of bone and mineral other than osteoporosis
    Richard L Prince
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia
    Med J Aust 180:354-9. 2004
  7. ncbi A cohort study of the effect of endogenous estrogen on spine fracture risk and bone structure in elderly women and an assessment of its diagnostic usefulness
    R L Prince
    School of Medicine and Pharmacology, Sir Charles Gairdner Hospital Unit, University of Western Australia, Australia
    Bone 41:33-8. 2007
  8. ncbi Klotho gene polymorphisms are associated with osteocalcin levels but not bone density of aged postmenopausal women
    B H Mullin
    Dept of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Western Australia, Australia
    Calcif Tissue Int 77:145-51. 2005
  9. ncbi Clinical, biochemical, hematologic, and radiographic responses in Paget's disease following intravenous pamidronate disodium: a 2-year study
    D H Gutteridge
    Department of Endocrinology, Sir Charles Gairdner Hospital, Nedlands, Australia
    Bone 19:387-94. 1996
  10. ncbi A randomized trial comparing hormone replacement therapy (HRT) and HRT plus calcitriol in the treatment of postmenopausal osteoporosis with vertebral fractures: benefit of the combination on total body and hip density
    D H Gutteridge
    Department of Endocrinology, Sir Charles Gairdner Hospital, Verdun Street, Nedlands, Western Australia 6009, Australia
    Calcif Tissue Int 73:33-43. 2003

Collaborators

Detail Information

Publications77

  1. ncbi Short and medium-term effects of an education self-management program for individuals with osteoarthritis of the knee, designed and delivered by health professionals: a quality assurance study
    Sophie Coleman
    Arthritis Foundation of Western Australia, PO Box 34, Wembley, Western Australia, 6913, Australia
    BMC Musculoskelet Disord 9:117. 2008
    ....
  2. ncbi Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women
    Richard L Prince
    School of Medicine and Pharmacology, Univerity of Western Australia, Perth, Australia
    Arch Intern Med 168:103-8. 2008
    ..We evaluated the effect of ergocalciferol and calcium citrate supplementation compared with calcium alone on the risk of falls in older women at high risk of falling...
  3. ncbi The clinical utility of measured kyphosis as a predictor of the presence of vertebral deformities
    R L Prince
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Osteoporos Int 18:621-7. 2007
    ....
  4. ncbi Calcium and vitamin D--for whom and when
    Richard L Prince
    School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Perth, WA 6009, Australia
    Menopause Int 13:35-7. 2007
    ....
  5. ncbi Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women
    Richard L Prince
    School of Medicine and Pharmacology, University of Western Australia, Australia
    Arch Intern Med 166:869-75. 2006
    ..We have examined whether calcium supplementation decreases clinical fracture risk in elderly women and its mechanism of action...
  6. ncbi 8: Disorders of bone and mineral other than osteoporosis
    Richard L Prince
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia
    Med J Aust 180:354-9. 2004
    ..These disorders range from nutritional deficiencies to complex genetic and metabolic diseases..
  7. ncbi A cohort study of the effect of endogenous estrogen on spine fracture risk and bone structure in elderly women and an assessment of its diagnostic usefulness
    R L Prince
    School of Medicine and Pharmacology, Sir Charles Gairdner Hospital Unit, University of Western Australia, Australia
    Bone 41:33-8. 2007
    ..The data suggest that the estrogen effect on reducing spine fracture is at least in part due to an effect on bone structure and its measurement does not significantly improve fracture prediction...
  8. ncbi Klotho gene polymorphisms are associated with osteocalcin levels but not bone density of aged postmenopausal women
    B H Mullin
    Dept of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Western Australia, Australia
    Calcif Tissue Int 77:145-51. 2005
    ....
  9. ncbi Clinical, biochemical, hematologic, and radiographic responses in Paget's disease following intravenous pamidronate disodium: a 2-year study
    D H Gutteridge
    Department of Endocrinology, Sir Charles Gairdner Hospital, Nedlands, Australia
    Bone 19:387-94. 1996
    ..Severe disease (Gp III) remains a challenge; regardless of dosage, the majority of patients will be in relapse 2 years after a single course of treatment...
  10. ncbi A randomized trial comparing hormone replacement therapy (HRT) and HRT plus calcitriol in the treatment of postmenopausal osteoporosis with vertebral fractures: benefit of the combination on total body and hip density
    D H Gutteridge
    Department of Endocrinology, Sir Charles Gairdner Hospital, Verdun Street, Nedlands, Western Australia 6009, Australia
    Calcif Tissue Int 73:33-43. 2003
    ..This is the first study comparing the 2 treatments in a fracture population. The results indicate a significant benefit of calcitriol combined with HRT on total body BMD and on BMD at the hip, the major site of osteoporotic fracture...
  11. ncbi Bone structural effects of variation in the TNFRSF1B gene encoding the tumor necrosis factor receptor 2
    B H Mullin
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, 6009
    Osteoporos Int 19:961-8. 2008
    ..We analysed the TNFRSF1B gene from this region, which encodes the TNF receptor 2, in two large population-based cohorts. Our results suggest that variation in TNFRSF1B is associated with BMD...
  12. ncbi Calcium-sensing receptor gene polymorphism A986S does not predict serum calcium level, bone mineral density, calcaneal ultrasound indices, or fracture rate in a large cohort of elderly women
    J Bollerslev
    School of Medicine and Pharmacology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Calcif Tissue Int 74:12-7. 2004
    ..It is questioned whether the polymorphism has any clinical significance for postmenopausal osteoporosis...
  13. ncbi A randomized clinical trial comparing oral alendronate and intravenous pamidronate for the treatment of Paget's disease of bone
    J P Walsh
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia
    Bone 34:747-54. 2004
    ..In patients previously treated with pamidronate, alendronate is more effective...
  14. ncbi Prediction of incident osteoporotic fractures in elderly women using the free estradiol index
    A Devine
    School of Medicine and Pharmacology, Sir Charles Gairdner Hospital, University of Western Australia, 4th Floor G Block, 6009, Nedlands, Western Australia, Australia
    Osteoporos Int 16:216-21. 2005
    ..These data confirm the importance of postmenopausal estrogen concentration in the pathogenesis of osteoporosis in elderly women...
  15. ncbi Prevalence and predictors of osteopenia and osteoporosis in adults with Type 1 diabetes
    E J Hamilton
    University of Western Australia, School of Medicine and Pharmacology, Fremantle, Australia
    Diabet Med 26:45-52. 2009
    ..To determine the prevalence and biochemical/hormonal determinants of osteopenia and osteoporosis in adults with Type 1 diabetes...
  16. ncbi Significant association between common polymorphisms in the aromatase gene CYP19A1 and bone mineral density in postmenopausal women
    B H Mullin
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Calcif Tissue Int 89:464-71. 2011
    ..None of these polymorphisms was significantly associated with circulating 17β-estradiol levels. In conclusion, common genetic variations within the CYP19A1 gene are significantly associated with aBMD in postmenopausal Caucasian women...
  17. ncbi Association of an aromatase TTTA repeat polymorphism with circulating estrogen, bone structure, and biochemistry in older women
    I M Dick
    School of Medicine and Pharmacology, Univ of Western Australia, 4th Floor G Block, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia
    Am J Physiol Endocrinol Metab 288:E989-95. 2005
    ....
  18. ncbi LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women
    J Bollerslev
    School of Medicine and Pharmacology, University of Western Australia, Nedlands
    Bone 36:599-606. 2005
    ..67 [1.02-2.78], P = 0.045), indicating factors other than bone mass are of importance for bone strength. In conclusion, genetic variation in LRP5 seems to be of importance for regulation of bone mass and osteoporotic fractures...
  19. ncbi The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly women
    K Zhu
    School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia
    Osteoporos Int 20:1183-91. 2009
    ..In our 5-year cohort study with 1,213 women aged 70-85 years, high homocysteine is associated with greater hip bone loss but not fracture risk. The effect of MTHFR genotype on bone density and fracture is weak...
  20. ncbi Calcitriol upregulates expression and activity of the 1b isoform of the plasma membrane calcium pump in immortalized distal kidney tubular cells
    P Glendenning
    Department of Medicine, University of Western Australia, Nedlands, Western Australia, 6009, Australia
    Arch Biochem Biophys 380:126-32. 2000
    ..Furthermore, they indicate that calcitriol is an important regulator of PMCA activity in the kidney distal tubule by a pathway that includes translation and posttranscriptional modification of PMCA1b...
  21. ncbi Bone density changes in Paget's disease 2 years after iv pamidronate: profound, sustained increases in pagetic bone with severity-related loss in forearm nonpagetic cortical bone
    D H Gutteridge
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, 6000 Western Australia, Australia
    Bone 32:56-61. 2003
    ..Severity-dependent nonpagetic forearm bone loss, persisting to 2 years at cortical sites, suggests a potential drug-induced fracture risk at the forearm and possibly elsewhere in the absence of appropriate preventive cotreatment...
  22. ncbi The effects of high potassium consumption on bone mineral density in a prospective cohort study of elderly postmenopausal women
    K Zhu
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Osteoporos Int 20:335-40. 2009
    ....
  23. ncbi The T869C TGF beta polymorphism is associated with fracture, bone mineral density, and calcaneal quantitative ultrasound in elderly women
    I M Dick
    Department of Medicine, Sir Charles Gairdner Hospital, University of Western Australia, Nedlands, WA, Australia
    Bone 33:335-41. 2003
    ..These findings are of potential clinical usefulness, as the TGF beta T869C genotype could be used, in conjunction with other genetic and clinical information, to determine an individual's risk of osteoporosis...
  24. ncbi Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women
    S Chew
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Australia
    Osteoporos Int 22:1981-6. 2011
    ..We found no evidence of association between UGT2B17 CNV and osteoporosis risk in this population...
  25. ncbi Bone mass effects of a BMP4 gene polymorphism in postmenopausal women
    L Ramesh Babu
    School of Medicine and Pharmacology, University of Western Australia, Nedlands, WA, Australia
    Bone 36:555-61. 2005
    ..We conclude that a polymorphism found in the BMP4 gene, affecting amino acid sequence, is associated with hip bone density in postmenopausal women, presumably via regulation of anabolic effects on the skeleton...
  26. ncbi Estrogen effects on the renal handling of calcium in the ovariectomized perfused rat
    I M Dick
    Department of Medicine, University of Western Australia, Nedlands, Western Australia
    Kidney Int 51:1719-28. 1997
    ....
  27. ncbi Differences in structural geometrical outcomes at the neck of the proximal femur using two-dimensional DXA-derived projection (APEX) and three-dimensional QCT-derived (BIT QCT) techniques
    B C C Khoo
    Medical Technology and Physics, Sir Charles Gairdner Hospital, Nedlands, Perth, WA, Australia
    Osteoporos Int 23:1393-8. 2012
    ..Linear correlations for parameters ranged from 0.45 to 0.90. The average value of the subperiosteal width, as determined by the two techniques, was the same; variables dependent on mass measurements were different...
  28. ncbi Effects of endogenous estrogen on renal calcium and phosphate handling in elderly women
    I M Dick
    School of Medicine and Pharmacology, Univ of Western Australia, 4th Floor G Block, Sir Charles Gairdner Hospital, Nedlands, WA, Australia 6009
    Am J Physiol Endocrinol Metab 288:E430-5. 2005
    ....
  29. ncbi The promoter region of the human PMCA1 gene mediates transcriptional downregulation by 1,25-dihydroxyvitamin D(3)
    P Glendenning
    Department of Medicine, University of Western Australia, Western Australia, Australia
    Biochem Biophys Res Commun 277:722-8. 2000
    ..7-kb core promoter...
  30. ncbi Adequacy and change in nutrient and food intakes with aging in a seven-year cohort study in elderly women
    K Zhu
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    J Nutr Health Aging 14:723-9. 2010
    ..The aims of this study were to investigate the changes in nutrient and dietary intakes that occurred with aging in a seven-year longitudinal study of elderly Australian women and to evaluate the adequacy of their dietary intakes...
  31. ncbi Comparison of QCT-derived and DXA-derived areal bone mineral density and T scores
    B C C Khoo
    Medical Technology and Physics, Sir Charles Gairdner Hospital, Perth, Australia
    Osteoporos Int 20:1539-45. 2009
    ..Transformation of the QCT aBMD values to T score values using National Health and Nutrition Examination Survey (NHANES) DXA-derived reference data improved agreement and clinical utility...
  32. ncbi Randomized controlled trial of the effects of calcium with or without vitamin D on bone structure and bone-related chemistry in elderly women with vitamin D insufficiency
    Kun Zhu
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    J Bone Miner Res 23:1343-8. 2008
    ..Vitamin D supplementation adds no extra short-term skeletal benefit to calcium citrate supplementation even in women with vitamin D insufficiency...
  33. ncbi The effect of estrogen on renal phosphorus handling in the rat
    I M Dick
    Department of Medicine, University of Western Australia, Nedlands, Australia
    Am J Nephrol 21:323-30. 2001
    ..There is some evidence that estrogen may also regulate renal phosphorus handling but it is not known if this is an effect of estrogen on filtered phosphorus load...
  34. ncbi Lifetime and five-year age-specific risks of first and subsequent osteoporotic fractures in postmenopausal women
    D A Doherty
    Department of Medicine, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia
    Osteoporos Int 12:16-23. 2001
    ..8% of women under the age of 55 years to 61.6% for women age 89 years and over. The increased risks of new fractures following a first fracture lead to a considerable burden of multiple fractures...
  35. ncbi Bioactivity of amino terminal fragments of parathyroid hormone and parathyroid hormone related peptide in rat kidney slices: no effect of dietary phosphate deprivation
    R L Prince
    Univ. Dept. of Medicine, University of Western Australia, Perth
    Horm Metab Res 22:569-72. 1990
    ....
  36. ncbi Effects of calcium and vitamin D supplementation on hip bone mineral density and calcium-related analytes in elderly ambulatory Australian women: a five-year randomized controlled trial
    Kun Zhu
    School of Medicine and Pharmacology, University of Western Australia, Crawley, Australia
    J Clin Endocrinol Metab 93:743-9. 2008
    ..Effects of long-term calcium, with or without vitamin D, on hip bone mineral density (BMD) and bone turnover in sunny climates have not been reported...
  37. ncbi In vivo short-term precision of hip structure analysis variables in comparison with bone mineral density using paired dual-energy X-ray absorptiometry scans from multi-center clinical trials
    Benjamin C C Khoo
    Department of Medical Technology and Physics, Sir Charles Gairdner Hospital and Western Australian Institute for Medical Research, Nedlands, WA 6009, Australia
    Bone 37:112-21. 2005
    ..The generally poorer precision of key HSA variables in comparison with conventional DXA-derived BMD highlights the critical roles played by correct limb repositioning and choice of an adequate and appropriately positioned ROI...
  38. ncbi A randomized trial of sodium fluoride (60 mg) +/- estrogen in postmenopausal osteoporotic vertebral fractures: increased vertebral fractures and peripheral bone loss with sodium fluoride; concurrent estrogen prevents peripheral loss, but not vertebral fra
    D H Gutteridge
    Department of Endocrinology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Osteoporos Int 13:158-70. 2002
    ..Our results and a literature review indicate that fluoride salts, if used, should be at low dosage, with pretreatment and co-treatment with a bone resorption inhibitor...
  39. ncbi Apolipoprotein E4 is associated with reduced calcaneal quantitative ultrasound measurements and bone mineral density in elderly women
    I M Dick
    Department of Medicine, University of Western Australia, Perth, WA, Australia
    Bone 31:497-502. 2002
    ....
  40. ncbi Bone mineral density and its determinants in diabetes: the Fremantle Diabetes Study
    V Rakic
    University of Western Australia, School of Medicine and Pharmacology, Fremantle Hospital, P.O. Box 480, Fremantle, WA 6959, Australia
    Diabetologia 49:863-71. 2006
    ..Low serum oestradiol concentrations may predispose to diabetes-associated osteoporosis regardless of sex...
  41. ncbi In vitro kinetic properties of the Thr201Met variant of human aromatase gene CYP19A1: functional responses to substrate and product inhibition and enzyme inhibitors
    E J Payne
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Perth, Western Australia 6009
    J Clin Endocrinol Metab 94:2998-3002. 2009
    ..The T(201)M variant (rs28757184) within exon 5 of the human aromatase gene CYP19A1, present in up to 20% of some populations, has been reported to reduce prostate cancer progression...
  42. ncbi Effects of zinc and other nutritional factors on insulin-like growth factor I and insulin-like growth factor binding proteins in postmenopausal women
    A Devine
    Department of Medicine, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands, Australia
    Am J Clin Nutr 68:200-6. 1998
    ..These results suggest that low zinc intake is associated with low IGF-I concentrations in healthy postmenopausal women and that the effects of zinc may be independent of protein intake...
  43. ncbi Predictors of low bone density in young adolescent females with anorexia nervosa and other dieting disorders
    J M Turner
    Department of Pediatrics, University of Western Australia and Eating Disorders Clinic, Princess Margaret Hospital for Children, Subiaco, Western Australia
    Int J Eat Disord 30:245-51. 2001
    ..To compare the bone density of adolescent patients with anorexia nervosa with adolescent patients with other dieting disorders and to evaluate risk factors for low bone density in these patients...
  44. ncbi A multimodal intervention to improve fragility fracture management in patients presenting to emergency departments
    Charles A Inderjeeth
    Osborne Park Hospital Program, North Metropolitan Area Health Service, Perth, WA, Australia
    Med J Aust 193:149-53. 2010
    ..To implement and evaluate a multimodal intervention to improve osteoporosis treatment in patients with a fragility fracture...
  45. ncbi Chocolate consumption and bone density in older women
    Jonathan M Hodgson
    Royal Perth Hospital Unit, the University of Western Australia School of Medicine and Pharmacology, Perth, Australia
    Am J Clin Nutr 87:175-80. 2008
    ..Nutrition is important for the development and maintenance of bone structure and for the prevention of osteoporosis and fracture. The relation of chocolate intake with bone has yet to be investigated...
  46. ncbi Drinking tea is associated with lower plasma total homocysteine in older women
    Jonathan M Hodgson
    University of Western Australia School of Medicine and Pharmacology, PO Box X2213, Perth, WA 6001, Australia
    Asia Pac J Clin Nutr 15:253-8. 2006
    ..The observed lower tHcy in women with higher tea intake is consistent in direction and magnitude with previous epidemiological studies, but any mechanisms remain unclear...
  47. ncbi Effects of vitamin D metabolites on intestinal calcium absorption and bone turnover in elderly women
    Amanda Devine
    Department of Medicine, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands, Australia
    Am J Clin Nutr 75:283-8. 2002
    ..The relative importance of vitamin D metabolites in the regulation of gut calcium absorption has not been well studied in elderly women living in an environment with abundant sunlight...
  48. ncbi Association of back pain frequency with mortality, coronary heart events, mobility, and quality of life in elderly women
    Kun Zhu
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Spine (Phila Pa 1976) 32:2012-8. 2007
    ..A 5-year observational cohort design using data from a randomized controlled trial of calcium intervention...
  49. ncbi Bone mass in young women is dependent on lean body mass
    Deborah Anne Kerr
    School of Public Health, Curtin University of Technology, Perth, Western Australia, Australia
    J Clin Densitom 10:319-26. 2007
    ..37, p<0.01; and r=0.34, p<0.01, respectively). No correlation was found between fat mass by DXA, UWW, and sum of skinfolds and BMD. These results indicate that bone mass in premenopausal women is dependent on lean body mass...
  50. ncbi Impact of the analysis of a bone density reference range on determination of the T-score
    Roger I Price
    Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Perth, Western Australia
    J Clin Densitom 6:51-62. 2003
    ..The hip BMDs of this study were greater than those of NHANES III in the third, seventh and eighth decades by as much as 0.6 SD. This produced a difference of 0.049-0.077 g/cm(2) for T(YN) = -2.5 between the two reference ranges...
  51. ncbi Estrogen and androgen regulation of plasma membrane calcium pump activity in immortalized distal tubule kidney cells
    Ian M Dick
    School of Medicine and Pharmacology, University of Western Australia, Nedlands, WA 6009, Australia
    Mol Cell Endocrinol 212:11-8. 2003
    ..and have significance for our understanding of estrogen and androgen deficient states on calcium transport...
  52. ncbi Protein consumption is an important predictor of lower limb bone mass in elderly women
    Amanda Devine
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Am J Clin Nutr 81:1423-8. 2005
    ..The effect of protein intake on bone density is uncertain, and evidence exists for beneficial effects of both low and high protein intakes...
  53. ncbi A randomized controlled trial of the effects of vitamin D on muscle strength and mobility in older women with vitamin D insufficiency
    Kun Zhu
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    J Am Geriatr Soc 58:2063-8. 2010
    ..To evaluate the effects of vitamin D treatment on muscle strength and mobility in older women with vitamin D insufficiency...
  54. ncbi Phenolic acid metabolites as biomarkers for tea- and coffee-derived polyphenol exposure in human subjects
    Jonathan M Hodgson
    University of Western Australia School of Medicine and Pharmacology, Royal Perth Hospital, Perth, Western Australia, Australia
    Br J Nutr 91:301-6. 2004
    ....
  55. ncbi Physical activity and calcium consumption are important determinants of lower limb bone mass in older women
    Amanda Devine
    School of Medicine and Pharmacology, University of Western Australia, Nedlands, Western Australia, Australia
    J Bone Miner Res 19:1634-9. 2004
    ..1% higher hip BMD than those who did not, supporting the concept that lifestyle factors play an important role in the maintenance of lower extremity bone mass in older women...
  56. ncbi Calcium supplementation and the risks of atherosclerotic vascular disease in older women: results of a 5-year RCT and a 4.5-year follow-up
    Joshua R Lewis
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Perth, Australia
    J Bone Miner Res 26:35-41. 2011
    ..This trial provides compelling evidence that calcium supplementation of 1200 mg daily does not significantly increase the risk of atherosclerotic vascular disease in elderly women...
  57. ncbi Comparison of genome screens for two independent cohorts provides replication of suggestive linkage of bone mineral density to 3p21 and 1p36
    S G Wilson
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Australia
    Am J Hum Genet 72:144-55. 2003
    ....
  58. ncbi Prevalence of lower extremity pain and its association with functionality and quality of life in elderly women in Australia
    Juan Chen
    School of Medicine and Pharmacology, University of Western Australia, Perth, West Australia, Australia
    J Rheumatol 30:2689-93. 2003
    ..In view of the availability of effective interventions to reduce joint pain, more aggressive intervention in the most disabled is indicated...
  59. ncbi Recreational physical activity levels in healthy older women: the importance of fear of falling
    David G Bruce
    Department of Medicine, University of Western Australia, Perth, Australia
    J Am Geriatr Soc 50:84-9. 2002
    ..Fear of falling is an important psychological barrier that may need to be overcome in programs attempting to improve activity levels in older women...
  60. ncbi A 5-year cohort study of the effects of high protein intake on lean mass and BMC in elderly postmenopausal women
    Xingqiong Meng
    Curtin Health Innovation Research Institute and School of Public Health, Curtin University of Technology, Perth, Western Australia, Australia
    J Bone Miner Res 24:1827-34. 2009
    ..This study shows that high protein intake is associated with long-term beneficial effects on muscle mass and size and bone mass in elderly women. The protein effect on bone may be partly mediated by its effects on muscle...
  61. ncbi Geometric indices of bone strength are associated with physical activity and dietary calcium intake in healthy older women
    Michelle K Nurzenski
    School of Physiotherapy, Curtin University of Technology, and Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Western Australia, Australia
    J Bone Miner Res 22:416-24. 2007
    ..4-4.4% higher femoral bone strength in axial compression and 1.7-5.2% in bending than those achieving low levels, indicating that lifestyle factors influence bone strength in the proximal femur...
  62. ncbi Effects of a herbal extract on the bone density, strength and markers of bone turnover of mature ovariectomized rats
    Min Xu
    Department of Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Am J Chin Med 31:87-101. 2003
    ..It may have potential as a new approach in treating and preventing postmenopausal osteoporosis (PMOP)...
  63. ncbi Under-reporting of energy intake in elderly Australian women is associated with a higher body mass index
    X Meng
    Curtin Health Innovation Research Institute and the School of Public Health, Curtin University, Perth, WA 6845, Australia
    J Nutr Health Aging 17:112-8. 2013
    ..Identify the extent of under-reporting of energy intake and the characteristics associated with implausible intakes in elderly women...
  64. ncbi Regulation of the 1b isoform of the plasma membrane calcium pump by 1,25-dihydroxyvitamin D3 in rat osteoblast-like cells
    P Glendenning
    Department of Medicine, University of Western Australia, Perth, Australia
    J Bone Miner Res 16:525-34. 2001
    ..These data provide evidence for the role of 1,25(OH)2D3 and PMCA1b in the regulation of calcium transport in bone cells...
  65. ncbi How to diagnose the presence of osteoporosis and assess the risk of fracture
    R L Prince
    Department of Medicine, University of Western Australia, Perth, Western Australia, 6009, Australia
    Best Pract Res Clin Rheumatol 15:345-58. 2001
    ..Methods of diagnosing the cause of the osteoporosis are also outlined. Finally, application of these techniques in clinical care is discussed...
  66. ncbi Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis
    Ben H Mullin
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, 6009, Australia
    Am J Hum Genet 82:1262-9. 2008
    ..In conclusion, genetic variation in ARHGEF3 plays a role in the determination of bone density in Caucasian women. This data implicates the RhoGTPase-RhoGEF pathway in osteoporosis...
  67. ncbi Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis
    Ben H Mullin
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Bone 45:387-91. 2009
    ..These results support the implication of the RhoGTPase-RhoGEF pathway in osteoporosis, and suggest that one or more genes in this pathway may be responsible for the linkage observed between 3p14-p21 and BMD...
  68. ncbi Expression of the HFE hemochromatosis gene in a community-based population of elderly women
    Enrico Rossi
    Department of Clinical Biochemistry, PathCentre Western Australian Centre for Pathology and Medical Research, Nedlands, Western Australia, Australia
    J Gastroenterol Hepatol 19:1150-4. 2004
    ..Recent studies suggest that the clinical penetrance of associated hereditary hemochromatosis, defined as either the C282Y homozygote or compound heterozygote HFE genotype status, is much lower than previously thought...
  69. ncbi Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro
    Scott G Wilson
    School of Medicine and Pharmacology, University of Western Australia, Western Australia, Australia
    J Bone Miner Res 24:1989-97. 2009
    ..Although the location of variants having effects is not entirely consistent, variation at the 5' end of the gene may reflect effects on levels of FLNB transcription efficiency...
  70. ncbi Do sleep problems or urinary incontinence predict falls in elderly women?
    Joy S H Teo
    School of Physiotherapy, Curtin University of Technology, Perth, Western Australia
    Aust J Physiother 52:19-24. 2006
    ..As urge incontinence and abnormal daytime sleepiness were independently associated with an increased falls risk, effective management of these problems may reduce the risk of falling in older women...
  71. ncbi Tea intake is inversely related to blood pressure in older women
    Jonathan M Hodgson
    University of Western Australia School of Medicine and Pharmacology, and the Western Australian Institute for Medical Research WAIMR, Western Australia, Australia
    J Nutr 133:2883-6. 2003
    ..The observed associations for both tea intake and 4-O-methylgallic acid are consistent with the hypothesis that long-term regular ingestion of tea may have a favorable effect on blood pressure in older women...
  72. ncbi Tea drinking is associated with benefits on bone density in older women
    Amanda Devine
    Nutrition Program, School of Exercise, Biomedical and Health Science, Edith Cowan University, 100 Joondalup Drive, Joondalup WA 6027 Australia
    Am J Clin Nutr 86:1243-7. 2007
    ..Impaired hip structure assessed by dual-energy X-ray absorptiometry (DXA) areal bone mineral density (aBMD) is an independent predictor for osteoporotic hip fracture. Some studies suggest that tea intake may protect against bone loss...
  73. ncbi Whole-body dual-energy x-ray absorptiometry comes of age: bone structural measures and their physiological determinants in anorexia nervosa
    Richard L Prince
    J Clin Endocrinol Metab 93:1178-80. 2008
  74. ncbi The importance of calculating absolute rather than relative fracture risk
    Graeme Tucker
    Health Statistics Unit, Department of Health, Government of South Australia, Adelaide, South Australia
    Bone 41:937-41. 2007
    ..We conclude that multiplicative factors can be applied to odds but not to risk and that multipliers of risk tend to overstate the effect of continuous variables, such as age and T-score, particularly towards the end of their ranges...
  75. ncbi EBM in action
    Richard L Prince
    Med J Aust 177:223-4; author reply 224. 2002
  76. ncbi Re: The perspective of the International Osteoporosis Foundation on the official positions of the International Society for Clinical Densitometry
    Richard L Prince
    Osteoporos Int 17:492; author reply 493-4. 2006
  77. ncbi Bone density and fracture risk
    B E Christopher Nordin
    Med J Aust 189:7-8. 2008