Michael Piper

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. doi Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones
    Michael Piper
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3DY, UK
    Neural Dev 10:3. 2015
  2. pmc The transcription factor Nfix is essential for normal brain development
    Christine E Campbell
    Dept of Biochemistry and New York State Center of Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, 3435 Main St, Buffalo, NY 14214, USA
    BMC Dev Biol 8:52. 2008
  3. pmc Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum
    Michael Piper
    School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia
    J Comp Neurol 519:3532-48. 2011
  4. pmc Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice
    Michael Piper
    Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia
    Neural Dev 4:43. 2009
  5. doi Specific glial populations regulate hippocampal morphogenesis
    Guy Barry
    The University of Queensland, Queensland Brain Institute, and School of Biomedical Sciences, Brisbane, 4067, Australia
    J Neurosci 28:12328-40. 2008
  6. doi NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1
    Michael Piper
    Queensland Brain Institute, The University of Queensland, Brisbane, Australia
    J Neurosci 30:9127-39. 2010
  7. doi Multiple Slits regulate the development of midline glial populations and the corpus callosum
    Divya K Unni
    The Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia
    Dev Biol 365:36-49. 2012
  8. pmc NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development
    Michael Piper
    Queensland Brain Institute, Institute for Molecular Bioscience, and the School of Biomedical Sciences, The University of Queensland, Brisbane, Australia 4069, QIMR Berghofer Medical Research Institute, Brisbane, Australia 4029, and Department of Biochemistry, Program in Genetics, Genomics and Bioinformatics, Center of Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, Buffalo, New York 14203
    J Neurosci 34:2921-30. 2014
  9. pmc Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones
    Michael Piper
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, United Kingdom
    Neuron 49:215-28. 2006
  10. pmc NF-protocadherin and TAF1 regulate retinal axon initiation and elongation in vivo
    Michael Piper
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, United Kingdom
    J Neurosci 28:100-5. 2008

Collaborators

Detail Information

Publications25

  1. doi Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones
    Michael Piper
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3DY, UK
    Neural Dev 10:3. 2015
    ..An intact cytoskeleton is critical to enact these responses, but it is not known whether the two major cytoskeletal elements, F-actin and microtubules, have any roles in regulating axonal protein synthesis...
  2. pmc The transcription factor Nfix is essential for normal brain development
    Christine E Campbell
    Dept of Biochemistry and New York State Center of Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, 3435 Main St, Buffalo, NY 14214, USA
    BMC Dev Biol 8:52. 2008
    ..Recently the Nfix gene has been disrupted and these studies indicated that there were largely uncharacterized defects in brain and skeletal development in Nfix-deficient mice...
  3. pmc Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum
    Michael Piper
    School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia
    J Comp Neurol 519:3532-48. 2011
    ....
  4. pmc Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice
    Michael Piper
    Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia
    Neural Dev 4:43. 2009
    ..Therefore, we investigate here how Nfib functions to regulate non-cell-autonomous mechanisms of callosal formation...
  5. doi Specific glial populations regulate hippocampal morphogenesis
    Guy Barry
    The University of Queensland, Queensland Brain Institute, and School of Biomedical Sciences, Brisbane, 4067, Australia
    J Neurosci 28:12328-40. 2008
    ..These data demonstrate a role for Nfib in hippocampal fissure and dentate gyrus formation, and that distinct glial bundles are critical for correct hippocampal morphogenesis...
  6. doi NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1
    Michael Piper
    Queensland Brain Institute, The University of Queensland, Brisbane, Australia
    J Neurosci 30:9127-39. 2010
    ....
  7. doi Multiple Slits regulate the development of midline glial populations and the corpus callosum
    Divya K Unni
    The Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia
    Dev Biol 365:36-49. 2012
    ..Finally, our data also indicate that some of the roles of Slit proteins at the midline may be independent of Robo signalling, suggestive of additional receptors regulating Slit signalling during development...
  8. pmc NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development
    Michael Piper
    Queensland Brain Institute, Institute for Molecular Bioscience, and the School of Biomedical Sciences, The University of Queensland, Brisbane, Australia 4069, QIMR Berghofer Medical Research Institute, Brisbane, Australia 4029, and Department of Biochemistry, Program in Genetics, Genomics and Bioinformatics, Center of Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, Buffalo, New York 14203
    J Neurosci 34:2921-30. 2014
    ..Collectively, these results suggest that the downregulation of Ezh2 transcription by NFIB is an important component of the process of neural progenitor cell differentiation during cortical development. ..
  9. pmc Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones
    Michael Piper
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, United Kingdom
    Neuron 49:215-28. 2006
    ..Our findings reveal an unexpected link between Slit2 and cofilin in growth cones and suggest that local translation of actin regulatory proteins contributes to repulsion...
  10. pmc NF-protocadherin and TAF1 regulate retinal axon initiation and elongation in vivo
    Michael Piper
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, United Kingdom
    J Neurosci 28:100-5. 2008
    ..These data provide evidence that NFPC regulates axon initiation and elongation and indicate a conserved role for TAF1, a transcriptional regulator, as a downstream cytosolic effector of NFPC in RGCs...
  11. ncbi Emx and Nfi genes regulate cortical development and axon guidance in the telencephalon
    Michael Piper
    The University of Queensland, Queensland Brain Institute and The School of Biomedical Sciences, Brisbane 4074, Australia
    Novartis Found Symp 288:230-242; discussion 242-5, 276-81. 2007
    ..We review the role of these genes in cortical cell migration, glial development and the formation of cortical axon projections, and examine the overlapping mutant phenotypes between the Emx and Nfi gene families...
  12. pmc Heterozygosity for nuclear factor one x affects hippocampal-dependent behaviour in mice
    Lachlan Harris
    The School of Biomedical Sciences, The University of Queensland, Brisbane, Australia
    PLoS ONE 8:e65478. 2013
    ..These findings demonstrate that the level of Nfix expression during development and within the adult is essential for the function of the hippocampus during learning and memory...
  13. pmc Electroporation of cDNA/Morpholinos to targeted areas of embryonic CNS in Xenopus
    Julien Falk
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    BMC Dev Biol 7:107. 2007
    ..Therefore, fine spatio-temporal control of over-expression or knock-down approaches is required to specifically address the role of a given gene in these processes...
  14. pmc Neuropilin 1-Sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum
    Michael Piper
    Queensland Brain Institute, The University of Queensland, Queensland, Australia
    Cereb Cortex 19:i11-21. 2009
    ..These data highlight a central role for Npn1 in the development of projections from the cingulate cortex and further illustrate the importance of these pioneer axons in the formation of the CC...
  15. pmc Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs
    Krishna H Zivraj
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK
    J Neurosci 30:15464-78. 2010
    ....
  16. pmc The role of cyclic nucleotides in axon guidance
    Michael Piper
    Department of Anatomy, University of Cambridge, UK
    Adv Exp Med Biol 621:134-43. 2007
    ....
  17. pmc Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation
    Michael Piper
    Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, United Kingdom
    Nat Neurosci 8:179-86. 2005
    ..These two phases of adaptation allow retinal axons to adjust their range of sensitivity to specific guidance cues...
  18. doi Nuclear factor one X regulates Bobby sox during development of the mouse forebrain
    Chantelle Dixon
    The School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia
    Cell Mol Neurobiol 33:867-73. 2013
    ..Moreover, we reveal that NFIX can repress Bbx promoter-driven expression. Collectively, these data suggest that Bbx is a downstream target of NFIX during development of the forebrain. ..
  19. ncbi CRIM1 regulates the rate of processing and delivery of bone morphogenetic proteins to the cell surface
    Lorine Wilkinson
    Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia
    J Biol Chem 278:34181-8. 2003
    ..The presence of CRIM1 reduced the effective BMP4 concentration of the media, thereby acting as a BMP4 antagonist. Hence, CRIM1 modulates BMP activity by affecting its processing and delivery to the cell surface...
  20. ncbi Movement through Slits: cellular migration via the Slit family
    Michael Piper
    Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia
    Bioessays 25:32-8. 2003
    ..This review focuses on the non-neuronal activities of Slit proteins, highlighting a common role for the Slit family in cellular migration...
  21. doi Nuclear factor I genes regulate neuronal migration
    Yee Hsieh Evelyn Heng
    School of Biomedical Sciences, Queensland Brain Institute, University of Queensland, Brisbane, QLD, Australia
    Neurosignals 20:159-67. 2012
    ....
  22. doi Nuclear factor one transcription factors in CNS development
    Sharon Mason
    Queensland Brain Institute, The University of Queensland, Building 79, St Lucia, 4072, Australia
    Mol Neurobiol 39:10-23. 2009
    ..Here, we discuss the importance and role of NFI in these processes in the context of several CNS systems including the neocortex, hippocampus, cerebellum, and spinal cord at both cellular and molecular levels...
  23. doi Nuclear factor one transcription factors: Divergent functions in developmental versus adult stem cell populations
    Lachlan Harris
    The School of Biomedical Sciences, The University of Queensland, Brisbane, Australia
    Dev Dyn 244:227-38. 2015
    ..Here we review the role of NFI factors in development, largely focusing on their role as promoters of stem cell differentiation, and attempt to reconcile this with the emerging role of NFIs in adult stem cell niches...
  24. ncbi Exogenous Slit2 does not affect ureteric branching or nephron formation during kidney development
    Michael Piper
    Institute for Molecular Bioscience, and Department of Biochemistry, University of Queensland, Brisbane, Australia
    Int J Dev Biol 46:545-50. 2002
    ..In situ analysis of the Slit receptors, Robo1 and Robo2, the vasculogenic markers VEGFA and Flk-1, and the stromal cell marker BF2 displayed no difference in comparison to controls...
  25. doi The neurodevelopmental hypothesis of schizophrenia: convergent clues from epidemiology and neuropathology
    Michael Piper
    School of Biomedical Science, University of Queensland, St Lucia, Queensland 4072, Australia
    Psychiatr Clin North Am 35:571-84. 2012
    ..Animal models involving early life exposures have been linked to changes in these same brain systems, providing convergent evidence for this long-standing hypothesis...