James O Pickles

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. ncbi The incorporation and turnover of radiolabelled amino acids in developing stereocilia of the chick cochlea
    J O Pickles
    Department of Physiology and Pharmacology, University of Queensland, Brisbane, Australia
    Hear Res 101:45-54. 1996
  2. ncbi Expression of Ephs and ephrins in developing mouse inner ear
    James O Pickles
    Vision Touch and Hearing Research Centre, School of Biomedical Sciences, University of Queensland, 4072, Brisbane, QLD, Australia
    Hear Res 178:44-51. 2003
  3. ncbi Complementary and layered expression of Ephs and ephrins in developing mouse inner ear
    James O Pickles
    Vision Touch and Hearing Research Centre, University of Queensland, 4072 Queensland, Australia
    J Comp Neurol 449:207-16. 2002
  4. ncbi Roles of fibroblast growth factors in the inner ear
    James O Pickles
    Vision, Touch and Hearing Research Centre, University of Queensland, St Lucia, QLD, Australia
    Audiol Neurootol 7:36-9. 2002
  5. ncbi The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear
    J O Pickles
    Vision, Touch and Hearing Research Centre, Department of Physiology and Pharmacology, University of Queensland, 4072, Brisbane, QLD, Australia
    Hear Res 155:54-62. 2001
  6. ncbi Lateral interactions account for the pattern of the hair cell array in the chick basilar papilla
    J O Pickles
    Vision, Touch and Hearing Research Centre, Department of Physiology and Pharmacology, University of Queensland, 4072, Brisbane, QLD, Australia
    Hear Res 145:65-74. 2000
  7. ncbi A tyrosine kinase screen of mouse vestibular maculae
    J O Pickles
    Vision, Touch and Hearing Research Centre, Department of Physiology and Pharmacology, University of Queensland, Brisbane, QLD, Australia
    Hear Res 136:100-4. 1999
  8. ncbi The expression of messenger RNAs coding for growth factors, their receptors, and eph-class receptor tyrosine kinases in normal and ototoxically damaged chick cochleae
    J O Pickles
    Vision, Touch and Hearing Research Centre, Department of Physiology and Pharmacology, Univeristy of Queensland, Brisbane, Australia
    Dev Neurosci 19:476-87. 1997
  9. ncbi Temporal and spatial expression of fibroblast growth factor receptor 4 isoforms in murine tissues
    Simon M Cool
    School of Biomedical Sciences, University of Queensland, Brisbane, QLD 4072, Australia
    Histochem J 34:291-7. 2002
  10. ncbi Mutation in mitochondrial DNA as a cause of presbyacusis
    James O Pickles
    Vision, Touch and Hearing Research Centre, School of Biomedical Sciences, University of Queensland, St Lucia, Australia
    Audiol Neurootol 9:23-33. 2004

Collaborators

  • Simon M Cool
  • Rosamond E Sayer
  • Victor Nurcombe
  • Walter R van Heumen

Detail Information

Publications10

  1. ncbi The incorporation and turnover of radiolabelled amino acids in developing stereocilia of the chick cochlea
    J O Pickles
    Department of Physiology and Pharmacology, University of Queensland, Brisbane, Australia
    Hear Res 101:45-54. 1996
    ..The results (i) give no support for the hypothesis that stereocilia grow from the tips, and (ii) suggest that during development at least some components of the stereocilia turn over with a relatively short time course...
  2. ncbi Expression of Ephs and ephrins in developing mouse inner ear
    James O Pickles
    Vision Touch and Hearing Research Centre, School of Biomedical Sciences, University of Queensland, 4072, Brisbane, QLD, Australia
    Hear Res 178:44-51. 2003
    ..The results suggest that the Ephs and ephrins are likely to play a part in the differentiation of the structures of the inner ear, and show which Ephs and ephrins are most likely to play important roles in the different structures...
  3. ncbi Complementary and layered expression of Ephs and ephrins in developing mouse inner ear
    James O Pickles
    Vision Touch and Hearing Research Centre, University of Queensland, 4072 Queensland, Australia
    J Comp Neurol 449:207-16. 2002
    ..The results suggest that the Eph system in the cochlea may have a role in maintaining cell segregation during phases of cochlear development...
  4. ncbi Roles of fibroblast growth factors in the inner ear
    James O Pickles
    Vision, Touch and Hearing Research Centre, University of Queensland, St Lucia, QLD, Australia
    Audiol Neurootol 7:36-9. 2002
    ..FGF1 and FGF2 act as trophic factors for the developing cochlear nerve fibres...
  5. ncbi The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear
    J O Pickles
    Vision, Touch and Hearing Research Centre, Department of Physiology and Pharmacology, University of Queensland, 4072, Brisbane, QLD, Australia
    Hear Res 155:54-62. 2001
    ..It is suggested that the different FGF receptors and ligands are expressed in a spatially coordinated pattern, to selectively program cochlear development...
  6. ncbi Lateral interactions account for the pattern of the hair cell array in the chick basilar papilla
    J O Pickles
    Vision, Touch and Hearing Research Centre, Department of Physiology and Pharmacology, University of Queensland, 4072, Brisbane, QLD, Australia
    Hear Res 145:65-74. 2000
    ..It is possible that the other factor is retinoic acid, a diffusive factor that promotes the formation of hair cells...
  7. ncbi A tyrosine kinase screen of mouse vestibular maculae
    J O Pickles
    Vision, Touch and Hearing Research Centre, Department of Physiology and Pharmacology, University of Queensland, Brisbane, QLD, Australia
    Hear Res 136:100-4. 1999
    ..The technique forms a powerful tool for analysing a range of the tyrosine kinases expressed, and provides a starting point for the analysis of cell-cell signalling in the inner ear...
  8. ncbi The expression of messenger RNAs coding for growth factors, their receptors, and eph-class receptor tyrosine kinases in normal and ototoxically damaged chick cochleae
    J O Pickles
    Vision, Touch and Hearing Research Centre, Department of Physiology and Pharmacology, Univeristy of Queensland, Brisbane, Australia
    Dev Neurosci 19:476-87. 1997
    ..The eph-class receptor tyrosine kinase CEK10 may be involved in cell interactions in the cochlear sensory epithelium, while CEK4 and CEK8 may play a role in the cochlear innervation...
  9. ncbi Temporal and spatial expression of fibroblast growth factor receptor 4 isoforms in murine tissues
    Simon M Cool
    School of Biomedical Sciences, University of Queensland, Brisbane, QLD 4072, Australia
    Histochem J 34:291-7. 2002
    ..Immunohistochemistry confirmed strong FGFR4-17b expression in the postnatal lung. When combined, the results suggest that FGFR4 variants play important roles particularly in lung and skeletal muscle development...
  10. ncbi Mutation in mitochondrial DNA as a cause of presbyacusis
    James O Pickles
    Vision, Touch and Hearing Research Centre, School of Biomedical Sciences, University of Queensland, St Lucia, Australia
    Audiol Neurootol 9:23-33. 2004
    ..It is moreover suggested that apoptosis of the vulnerable cells of the inner ear may to some extent be preventable, or at least delayed...