Research Topics
Species | Kathy PetoumenosSummaryAffiliation: University of New South Wales Country: Australia Publications
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Publications
The role of observational data in monitoring trends in antiretroviral treatment and HIV disease stage: results from the Australian HIV observational databaseKathy Petoumenos
National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Level 2, Victoria Street, Darlinghurst, NSW 2010, Australia
J Clin Virol 26:209-22. 2003..To illustrate how human immunodeficiency virus (HIV) observational databases may be used to monitor trends in HIV treatment and HIV disease outcomes through data reported from the Australian HIV Observational Database (AHOD)...
Antiretroviral treatment change among HIV, hepatitis B virus and hepatitis C virus co-infected patients in the Australian HIV Observational DatabaseK Petoumenos
National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
HIV Med 6:155-63. 2005....
Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factorsKathy Petoumenos
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia
J Int AIDS Soc 13:51. 2010..This retrospective survey describes types of cancers diagnosed in HIV-infected subjects in Asia, and assesses risk factors for cancer in HIV-infected subjects using contemporaneous HIV-infected controls without cancer...
Risk factors and causes of death in the Australian HIV Observational DatabaseKathy Petoumenos
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Darlinghurst, Australia
Sex Health 3:103-12. 2006..The objective of this paper was to examine causes of deaths in the Australian HIV Observational Database (AHOD) and compare risk factors for HIV-related and HIV-unrelated deaths...
Rates of cardiovascular disease following smoking cessation in patients with HIV infection: results from the D:A:D study(*)K Petoumenos
AHOD, National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia
HIV Med 12:412-21. 2011..The aim of the study was to estimate the rates of cardiovascular disease (CVD) events after stopping smoking in patients with HIV infection...
Virological responses during treatment for recent hepatitis C virus: potential benefit for ribavirin use in HCV/HIV co-infectionJason Grebely
The Kirby Institute for Infection and Immunity in Society, University of New South Wales UNSW, Sydney, Australia
AIDS 26:1653-61. 2012..This study evaluated early virological decline during recent HCV therapy in HIV-uninfected individuals receiving pegylated interferon (PEG-IFN) monotherapy and HIV-infected individuals receiving PEG-IFN/RBV...
Factors associated with uptake of treatment for recent hepatitis C virus infection in a predominantly injecting drug user cohort: The ATAHC StudyJ Grebely
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, 376 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
Drug Alcohol Depend 107:244-9. 2010..Decisions about whether to initiate treatment for recently acquired HCV were mainly driven by clinical factors, rather than factors related to sociodemographics or injecting behaviors...
Effect of pegylated interferon-α-2a treatment on mental health during recent hepatitis C virus infectionMaryam Alavi
The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
J Gastroenterol Hepatol 27:957-65. 2012..Data on the effect of HCV treatment on mental health among injecting drug users (IDUs) are limited. We assessed mental health during treatment of recently acquired HCV, within a predominantly IDU population...
Adherence to treatment for recently acquired hepatitis C virus (HCV) infection among injecting drug usersJason Grebely
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
J Hepatol 55:76-85. 2011..We assessed 80/80 adherence (≥80% of PEG-IFN doses, ≥80% treatment), on-treatment adherence, and treatment completion in a study of treatment of recent HCV infection (ATAHC)...
Hepatitis C virus reinfection and superinfection among treated and untreated participants with recent infectionJason Grebely
Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
Hepatology 55:1058-69. 2012..Conclusion: Reinfection and superinfection can occur during treatment of recent HCV and are associated with poor social functioning and ongoing IDU. ALT levels may be a useful clinical marker of reexposure...
Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infectionJason Grebely
National Centre in HIV Epidemiology and Clinical Research NCHECR, University of New South Wales UNSW, Sydney, Australia
Hepatology 52:1216-24. 2010..Early therapeutic intervention could be recommended for individuals with unfavorable IL28B genotypes...
Evolution of CD4+ T cell count in HIV-1-infected adults receiving antiretroviral therapy with sustained long-term virological suppressionHelen Byakwaga
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, 376 Victoria Street, Darlinghurst, NSW 2010, Australia
AIDS Res Hum Retroviruses 25:756-76. 2009..Our results point to an advantage to commencing ART at higher CD4+ T cell strata. These data should be considered when estimating the optimal time to initiate ART...
Poor baseline immune function predicts an incomplete immune response to combination antiretroviral treatment despite sustained viral suppressionKathleen Falster
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
J Acquir Immune Defic Syndr 50:307-13. 2009..To determine the prevalence and predictors of an incomplete immune response in patients with sustained viral suppression after starting their first or second combination antiretroviral treatment (cART) regimen...
Long-term patterns in CD4 response are determined by an interaction between baseline CD4 cell count, viral load, and time: The Asia Pacific HIV Observational Database (APHOD)Sam Egger
Cancer Council New South Wales, Woolloomooloo, Sydney, New South Wales, Australia
J Acquir Immune Defic Syndr 50:513-20. 2009..Random effects models were used to explore how the shape of CD4 cell count responses after commencing combination antiretroviral therapy (cART) develop over time and, in particular, the role of baseline and follow-up covariates...
Poly-l-lactic acid for HIV-1 facial lipoatrophy: 48-week follow-upD Carey
National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, NSW, Australia
HIV Med 10:163-72. 2009..Poly-l-lactic acid (PLA) injections modestly increase objectively assessed facial thickness but not facial soft tissue volume (FSTV) over 24 weeks. The durability of this response has not been well defined objectively...
The Clinical Significance of CD4 Counts in Asian and Caucasian HIV-Infected Populations: Results from TAHOD and AHODAmit C Achhra
National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, UNSW, Sydney, Australia
J Int Assoc Physicians AIDS Care (Chic) 10:160-70. 2011..At any given CD4 count, risk of AIDS or death was not found to vary by ethnicity, suggesting that the CD4 count thresholds for predicting outcomes defined in Caucasian populations may be equally valid in Asian populations...
Effective treatment of injecting drug users with recently acquired hepatitis C virus infectionGregory J Dore
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
Gastroenterology 138:123-35.e1-2. 2010..We evaluated the efficacy of treatment of recent HCV infection in IDUs with acute and early chronic HCV...
Triple class experience after initiation of combination antiretroviral treatment in Australia: survival and projectionsSadaf Marashi Pour
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW 2052, Australia
Sex Health 8:295-303. 2011..This study aims to investigate factors associated with becoming TCE and to explore the effect of becoming TCE on survival. We also project the prevalence of TCE in Australia to 2012...
Patterns and characteristics of hepatitis C transmission clusters among HIV-positive and HIV-negative individuals in the Australian trial in acute hepatitis CG V Matthews
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Australia
Clin Infect Dis 52:803-11. 2011..The extent to which these separate epidemics overlap is unknown...
Trends in detectable viral load by calendar year in the Australian HIV observational databaseMatthew G Law
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia
J Int AIDS Soc 14:10. 2011..We assessed calendar trends in detectable viral load in patients recruited to the Australian HIV Observational Database who were receiving cART...
Efavirenz versus boosted atazanavir or zidovudine and abacavir in antiretroviral treatment-naive, HIV-infected subjects: week 48 data from the Altair studyRebekah L Puls
National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, University of New South Wales, 45 Beach St, Coogee, New South Wales, Australia, 2034
Clin Infect Dis 51:855-64. 2010..Antiretroviral therapy is complicated by drug interactions and contraindications. Novel regimens are needed...
Characteristics and treatment outcomes among HIV-infected individuals in the Australian Trial in Acute Hepatitis CG V Matthews
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
Clin Infect Dis 48:650-8. 2009..Enrollment is open to both human immunodeficiency virus (HIV)-infected and -uninfected individuals. The aim of this article was to evaluate characteristics and virological outcomes among HIV-infected individuals enrolled in ATAHC...
Lipid profiles in HIV-infected adults receiving atazanavir and atazanavir/ritonavir: systematic review and meta-analysis of randomized controlled trialsDianne Carey
National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney 2052, New South Wales, Australia
J Antimicrob Chemother 65:1878-88. 2010..To compare lipid profiles in HIV-infected adults receiving atazanavir-based regimens...
Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysisDorothy A Machalek
The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia
Lancet Oncol 13:487-500. 2012..We aimed to assess available data for anal HPV disease that can inform pre-cancer screening programmes...
HIV infection, aging and cardiovascular disease: epidemiology and preventionKathy Petoumenos
The Kirby Institute, University of New South Wales, Sydney, NSW, Australia
Sex Health 8:465-73. 2011..A better understanding the mechanisms of CVD risk in this aging population and further efforts in improving uptake of prevention strategies will remain an important research area...
Trends in antiretroviral treatment use and treatment response in three Australian states in the first decade of combination antiretroviral treatmentKathleen Falster
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW 2010, Australia
Sex Health 5:141-54. 2008..To determine if there were any differences in antiretroviral treatment (ART) use across the three eastern states of Australia, New South Wales (NSW), Victoria and Queensland, during the period 1997 to 2006...
The role of hydroxyurea in enhancing the virologic control achieved through structured treatment interruption in primary HIV infection: final results from a randomized clinical trial (Pulse)Mark T Bloch
Holdsworth House Medical Practice, Sydney, New South Wales, Australia
J Acquir Immune Defic Syndr 42:192-202. 2006..196 cells, respectively, P = 0.006). CONCLUSIONS: Hydroxyurea was not found to be beneficial when used in association with STIs in patients during PHI...
Long-term survival in HIV positive patients with up to 15 Years of antiretroviral therapyHamish McManus
The Kirby Institute, UNSW, Sydney, New South Wales, Australia
PLoS ONE 7:e48839. 2012..We examined long-term survival in HIV-positive patients receiving cART in the Australian HIV Observational Database (AHOD), to describe changes in mortality compared to the general population and to develop longer-term survival models...
HIV immune escape at an immunodominant epitope in HLA-B*27-positive individuals predicts viral load outcomePalanee Ammaranond
Immunovirology Laboratory, St Vincent s Centre for Applied Medical Research, Darlinghurst, New South Wales, Australia
J Immunol 186:479-88. 2011..The only factor to affect viral load was the presence of the R264 escape mutations at the immunodominant epitope. CTL escape at R264 in the KK10 epitope is a major determinant of subsequent viral load in these HLA-B*27(+) individuals...
Predicting the short-term risk of diabetes in HIV-positive patients: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) studyKathy Petoumenos
AHOD, The Kirby Institute, University of New South Wales, Sydney, Australia
J Int AIDS Soc 15:17426. 2012..This study aims to develop a model to predict the short-term (six-month) risk of DM in HIV-positive populations and to compare the existing models developed in the general population...
A randomized, multicenter, open-label study of poly-L-lactic acid for HIV-1 facial lipoatrophyDianne L Carey
National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
J Acquir Immune Defic Syndr 46:581-9. 2007..Facial lipoatrophy can stigmatize and can reduce quality of life, self esteem, and antiretroviral adherence. Poly-L-lactic acid (PLA) injections seem safe and effective, but no randomized study has included objective endpoints...
Evaluation of self-collected samples in contrast to practitioner-collected samples for detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis by polymerase chain reaction among women living in remote areasJanet Knox
Sexual Health Unit of Territory Health Services, Alice Springs, Northern Territory, Australia
Sex Transm Dis 29:647-54. 2002..The low sensitivity of N gonorrhoeae PCR of urine specimens may reflect poor transport and storage conditions, which we have shown can be improved by freezing urine specimens and reducing transport delays...
