C Pantelis

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. doi request reprint Predicting the diagnosis of autism spectrum disorder using gene pathway analysis
    E Skafidas
    Centre for Neural Engineering, The University of Melbourne, Parkville, Vic, Australia
    Mol Psychiatry 19:504-10. 2014
  2. pmc Reduced orbitofrontal cortical thickness in male adolescents with internet addiction
    Soon Beom Hong
    Melbourne Neuropsychiatry Center, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Victoria, Australia
    Behav Brain Funct 9:11. 2013
  3. ncbi request reprint Managing patients with "treatment-resistant" schizophrenia
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, University of Melbourne at Sunshine Hospital, St Albans, Vic
    Med J Aust 178:S62-6. 2003
  4. ncbi request reprint Neuroimaging and emerging psychotic disorders: the Melbourne ultra-high risk studies
    C Pantelis
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Royal Melbourne Hospital, Sunshine Hospital, 176 Furlong Road, St Albans, Victoria 3021, Australia
    Int Rev Psychiatry 19:371-81. 2007
  5. ncbi request reprint Spatial working memory deficits in schizophrenia: relationship with tardive dyskinesia and negative symptoms
    C Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, University of Melbourne, Sunshine Hospital, St Albans, Victoria 3021, Australia
    Am J Psychiatry 158:1276-85. 2001
  6. ncbi request reprint The cognitive neuropsychiatric approach to investigating the neurobiology of schizophrenia and other disorders
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, Sunshine Hospital, 176 Furlong Road, St Albans, VIC 3021, Australia
    J Psychosom Res 53:655-64. 2002
  7. ncbi request reprint Early and late neurodevelopmental disturbances in schizophrenia and their functional consequences
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, Sunshine Hospital, 176 Furlong Road, St Albans, 3021, Victoria, Australia
    Aust N Z J Psychiatry 37:399-406. 2003
  8. ncbi request reprint Attentional set-shifting ability in first-episode and established schizophrenia: Relationship to working memory
    Christos Pantelis
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Sunshine Hospital, St Albans, Victoria 3021, Australia
    Schizophr Res 112:104-13. 2009
  9. ncbi request reprint Relationship of behavioural and symptomatic syndromes in schizophrenia to spatial working memory and attentional set-shifting ability
    C Pantelis
    Melbourne Neuropsychiatry Centre, The University of Melbourne, Parkville and Sunshine Hospital, St Albans, Victoria, Australia
    Psychol Med 34:693-703. 2004
  10. ncbi request reprint Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, and Melbourne Neuropsychiatry Centre, Mental Health Programme, Department of Psychiatry, University of Melbourne and Sunshine Hospital, Victoria, Melbourne, Australia
    Lancet 361:281-8. 2003

Detail Information

Publications139 found, 100 shown here

  1. doi request reprint Predicting the diagnosis of autism spectrum disorder using gene pathway analysis
    E Skafidas
    Centre for Neural Engineering, The University of Melbourne, Parkville, Vic, Australia
    Mol Psychiatry 19:504-10. 2014
    ..While SNPs differ across ethnic groups, our pathway approach identified cellular processes common to ASD across ethnicities. Our results have wide implications for detection, intervention and prevention of ASD. ..
  2. pmc Reduced orbitofrontal cortical thickness in male adolescents with internet addiction
    Soon Beom Hong
    Melbourne Neuropsychiatry Center, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Victoria, Australia
    Behav Brain Funct 9:11. 2013
    ..On the basis of recently proposed theoretical models of addiction, we predicted a reduction of thickness in the OFC of internet addicted individuals...
  3. ncbi request reprint Managing patients with "treatment-resistant" schizophrenia
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, University of Melbourne at Sunshine Hospital, St Albans, Vic
    Med J Aust 178:S62-6. 2003
    ..Although pharmacological treatment is a necessary first step in managing incompletely recovered patients, adjunctive psychosocial interventions are needed to optimise treatment success...
  4. ncbi request reprint Neuroimaging and emerging psychotic disorders: the Melbourne ultra-high risk studies
    C Pantelis
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Royal Melbourne Hospital, Sunshine Hospital, 176 Furlong Road, St Albans, Victoria 3021, Australia
    Int Rev Psychiatry 19:371-81. 2007
    ..Further, active changes during transition to illness may present the potential to intervene and ameliorate these changes with potential benefit clinically...
  5. ncbi request reprint Spatial working memory deficits in schizophrenia: relationship with tardive dyskinesia and negative symptoms
    C Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, University of Melbourne, Sunshine Hospital, St Albans, Victoria 3021, Australia
    Am J Psychiatry 158:1276-85. 2001
    ..This study examined the interrelationship between negative symptoms, orofacial tardive dyskinesia, and specific neurocognitive processes, particularly those involved in memory and executive function, in patients with schizophrenia...
  6. ncbi request reprint The cognitive neuropsychiatric approach to investigating the neurobiology of schizophrenia and other disorders
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, Sunshine Hospital, 176 Furlong Road, St Albans, VIC 3021, Australia
    J Psychosom Res 53:655-64. 2002
    ..Further, an assessment of the brain-behaviour relationships through this emerging discipline provides testable models for further study, using a range of techniques including functional and other imaging techniques...
  7. ncbi request reprint Early and late neurodevelopmental disturbances in schizophrenia and their functional consequences
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, Sunshine Hospital, 176 Furlong Road, St Albans, 3021, Victoria, Australia
    Aust N Z J Psychiatry 37:399-406. 2003
    ..In this paper we review the timing of structural changes in schizophrenia and argue that schizophrenia is a neuro-developmental disorder with limited progressive brain changes occurring during the evolution and early phase of psychosis...
  8. ncbi request reprint Attentional set-shifting ability in first-episode and established schizophrenia: Relationship to working memory
    Christos Pantelis
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Sunshine Hospital, St Albans, Victoria 3021, Australia
    Schizophr Res 112:104-13. 2009
    ..Longitudinal studies assessing these cognitive functions from illness onset or in prepsychotic individuals are required...
  9. ncbi request reprint Relationship of behavioural and symptomatic syndromes in schizophrenia to spatial working memory and attentional set-shifting ability
    C Pantelis
    Melbourne Neuropsychiatry Centre, The University of Melbourne, Parkville and Sunshine Hospital, St Albans, Victoria, Australia
    Psychol Med 34:693-703. 2004
    ..Few studies have assessed their relationship with neuropsychological deficits. We hypothesized that these syndromes may represent behavioural manifestations of frontal-subcortical impairments, previously described in schizophrenia...
  10. ncbi request reprint Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, and Melbourne Neuropsychiatry Centre, Mental Health Programme, Department of Psychiatry, University of Melbourne and Sunshine Hospital, Victoria, Melbourne, Australia
    Lancet 361:281-8. 2003
    ..We investigated this issue with MRI to study people with prodromal symptoms who are at ultra high-risk for the development of psychosis...
  11. ncbi request reprint Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophrenia
    Christos Pantelis
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, Royal Melbourne Hospital, Sunshine Hospital, Victoria
    Schizophr Bull 31:672-96. 2005
    ....
  12. ncbi request reprint Characterizing anterior cingulate activation in chronic schizophrenia: a group and single-subject fMRI study
    B J Harrison
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia
    Acta Psychiatr Scand 116:271-9. 2007
    ..In this study, we sought to further evaluate the notion of dAC hypofunction in chronic schizophrenia patients using a cognitive task specifically designed to activate this region, enabling both group and single-subject level analyses...
  13. ncbi request reprint Spatial working memory ability is a marker of risk-for-psychosis
    S J Wood
    Cognitive Neuropsychiatry Research and Academic Unit, PACE Clinic, Department of Psychiatry, University of Melbourne, Sunshine Hospital, St Albans, Vic, Australia
    Psychol Med 33:1239-47. 2003
    ..Working memory has been identified as a core cognitive deficit in schizophrenia that is associated with negative symptoms, but it is unclear whether it is impaired prior to onset of psychosis in symptomatic patients...
  14. ncbi request reprint Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, University of Melbourne and Sunshine Hospital, Melbourne, Australia
    Schizophr Bull 29:831-43. 2003
    ..This finding did not discriminate between those UHR individuals who later became psychotic and those who did not...
  15. ncbi request reprint A longitudinal study of hippocampal volume in first episode psychosis and chronic schizophrenia
    S J Wood
    The Cognitive Neuropsychiatry Research and Academic Unit, The University of Melbourne and Sunshine Hospital, Melbourne, Australia
    Schizophr Res 52:37-46. 2001
    ..Alternatively, the period before the onset of frank psychotic symptoms may be the point of greatest risk for progressive change...
  16. doi request reprint Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Australia
    Arch Gen Psychiatry 66:366-76. 2009
    ..It is unknown whether these progressive processes predate the onset of psychosis...
  17. doi request reprint Neurocognitive predictors of functional outcome two to 13 years after identification as ultra-high risk for psychosis
    A Lin
    Orygen Youth Health Research Centre and Centre for Youth Mental Health, University of Melbourne, Australia
    Schizophr Res 132:1-7. 2011
    ..This longitudinal study aimed to investigate neurocognitive predictors of poor functional outcome in a group identified as ultra-high risk (UHR) for psychosis between two and 13 years prior...
  18. ncbi request reprint Neurocognitive predictors of transition to psychosis: medium- to long-term findings from a sample at ultra-high risk for psychosis
    A Lin
    Orygen Youth Health Research Centre and Centre for Youth Mental Health, University of Melbourne, Australia
    Psychol Med 43:2349-60. 2013
    ....
  19. ncbi request reprint Stability of olfactory identification deficits in neuroleptic-naive patients with first-episode psychosis
    W J Brewer
    Cognitive Neuropsychiatry Research, University of Melbourne, Parkville, Melbourne, Australia
    Am J Psychiatry 158:107-15. 2001
    ..Olfactory identification deficits and their relationship to negative symptoms in patients with schizophrenia were examined in patients with recent-onset psychosis, the majority of whom were neuroleptic naive...
  20. ncbi request reprint Anterior cingulate activation during Stroop task performance: a PET to MRI coregistration study of individual patients with schizophrenia
    Murat Yucel
    Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, Howard Florey Institute, University of Melbourne, Victoria, Australia
    Am J Psychiatry 159:251-4. 2002
    ....
  21. doi request reprint Meta-analysis of volumetric abnormalities in cortico-striatal-pallidal-thalamic circuits in major depressive disorder
    E Bora
    Department of Psychiatry, The University of Melbourne and Melbourne Health, Vic, Australia
    Psychol Med 42:671-81. 2012
    ..However, the robustness of these findings across studies is unclear, as is the extent to which they are influenced by demographic, clinical and pharmacological factors...
  22. ncbi request reprint Selective bilateral hippocampal volume loss in chronic schizophrenia
    D Velakoulis
    Applied Schizophrenia Division, Mental Health Research Institute of Victoria, Melbourne, Australia
    Biol Psychiatry 50:531-9. 2001
    ..Group discrimination on the basis of hippocampal volume and shape measures was moderately good. A full three-dimensional analysis of hippocampal shape, based on large samples, would be a useful extension of the study...
  23. ncbi request reprint Visuospatial memory and learning in first-episode schizophreniform psychosis and established schizophrenia: a functional correlate of hippocampal pathology?
    S J Wood
    Cognitive Neuropsychiatry Research and Academic Unit, University of Melbourne, Sunshine Hospital, St Albans, Victoria, Australia
    Psychol Med 32:429-38. 2002
    ..Given the reported findings of reduced hippocampal volume in schizophrenia, we used a theoretically sensitive test of the right medial temporal lobe to determine the nature of the visuospatial memory deficit in the disorder...
  24. ncbi request reprint Hippocampal and amygdala volumes according to psychosis stage and diagnosis: a magnetic resonance imaging study of chronic schizophrenia, first-episode psychosis, and ultra-high-risk individuals
    Dennis Velakoulis
    Melbourne Neuropsychiatry Centre and Department of Psychiatry, University of Melbourne, Australia
    Arch Gen Psychiatry 63:139-49. 2006
    ..These studies have been limited by small samples and the absence of patients early in the course of illness...
  25. doi request reprint Prevalence of large cavum septi pellucidi in ultra high-risk individuals and patients with psychotic disorders
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 105:236-44. 2008
    ..These findings suggest that the CSP is not a neurodevelopmental marker of psychosis and cast doubt over the notion that it plays a major role in the neurobiology of psychosis...
  26. ncbi request reprint Dysfunction of dorsolateral prefrontal cortex in antipsychotic-naïve schizophreniform psychosis
    Ben J Harrison
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Australia
    Psychiatry Res 148:23-31. 2006
    ....
  27. ncbi request reprint Comparison of set-shifting ability in patients with chronic schizophrenia and frontal lobe damage
    C Pantelis
    Department of Psychiatry, The University of Melbourne, Parkville, Australia
    Schizophr Res 37:251-70. 1999
    ..The relevance of these findings to understanding the nature of prefrontal cortical deficits in chronic schizophrenia is discussed. The implication of these findings to the rehabilitation of these patients is considered...
  28. doi request reprint A disturbed sense of self in the psychosis prodrome: linking phenomenology and neurobiology
    B Nelson
    Orygen Youth Health Research Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia
    Neurosci Biobehav Rev 33:807-17. 2009
    ..Further empirical work examining the relationship between neurobiological and phenomenological variables may be of value in identifying risk markers for psychosis onset...
  29. ncbi request reprint Evidence for progression of brain structural abnormalities in schizophrenia: beyond the neurodevelopmental model
    D Velakoulis
    Cognitive Neuropsychiatry Research and Academic Unit, University of Melbourne and Sunshine Hospital, St Albans, Victoria, Australia
    Aust N Z J Psychiatry 34:S113-26. 2000
    ....
  30. ncbi request reprint Neuropsychological deficits in obsessive-compulsive disorder: a comparison with unipolar depression, panic disorder, and normal controls
    R Purcell
    Department of Psychology, The University of Melbourne, Royal Melbourne Hospital, Australia
    Arch Gen Psychiatry 55:415-23. 1998
    ..We directly compared cognitive function in patients with OCD with that in matched patients with unipolar depression and panic disorder and healthy control subjects to establish the specific nature of neuropsychological deficits in OCD...
  31. ncbi request reprint Major psychoses with mixed psychotic and mood symptoms: are mixed psychoses associated with different neurobiological markers?
    E Bora
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, and Melbourne Health, ORYGEN Research Centre, The University of Melbourne, Melbourne, Vic, Australia
    Acta Psychiatr Scand 118:172-87. 2008
    ..As controversies mainly arise in mixed psychoses that occupy the intermediate zone between schizophrenia and BD, investigating neurobiological markers of mixed psychoses may be relevant to understanding the nature of psychotic disorders...
  32. ncbi request reprint Ethyl-eicosapentaenoic acid in first-episode psychosis. A 1H-MRS study
    Gregor E Berger
    Department of Psychiatry, ORYGEN Research Centre, University of Melbourne, Parkville, Australia
    Neuropsychopharmacology 33:2467-73. 2008
    ..Larger confirmatory studies of these postulated metabolic brain effects of E-EPA are warranted...
  33. doi request reprint Superior temporal gyrus volume in antipsychotic-naive people at risk of psychosis
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, c o National Neuroscience Facility, 161 Barry Street, Carlton South, Victoria 3053, Australia
    Br J Psychiatry 196:206-11. 2010
    ..Morphological abnormalities of the superior temporal gyrus have been consistently reported in schizophrenia, but the timing of their occurrence remains unclear...
  34. ncbi request reprint Functional connectivity during Stroop task performance
    Ben J Harrison
    Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
    Neuroimage 24:181-91. 2005
    ..These findings may also provide some additional insight into the nature of anterior cingulate- and prefrontal cortical contributions to implementing cognitive control in the brain...
  35. doi request reprint Theory of mind impairment in schizophrenia: meta-analysis
    Emre Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Vic, Australia
    Schizophr Res 109:1-9. 2009
    ..Our review also suggests that future research should consider the potential moderating influence of IQ deficits on ToM performance in "remitted" patients, as well as the potential effects of residual symptoms...
  36. pmc Effects of NRG1 and DAOA genetic variation on transition to psychosis in individuals at ultra-high risk for psychosis
    C A Bousman
    Melbourne Brain Centre, Department of Psychiatry, The University of Melbourne, Parkville, Vic, Australia
    Transl Psychiatry 3:e251. 2013
    ..None of the assessed DAOA htSNPs were associated with transition. Our findings suggest NRG1 genetic variation may improve our ability to identify UHR individuals at risk for transition to psychosis...
  37. ncbi request reprint Anterior cingulate activation in antipsychotic-naïve first-episode schizophrenia
    M Yucel
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Carlton South, VIC 3053, Australia
    Acta Psychiatr Scand 115:155-8. 2007
    ..Anterior cingulate (ACC) hypo-activity is commonly observed in chronically ill schizophrenia patients. However, it is unclear whether this is secondary to persistent illness and/or medication...
  38. ncbi request reprint A combined spectroscopic and functional MRI investigation of the dorsal anterior cingulate region in opiate addiction
    M Yucel
    ORYGEN Research Centre, Melbourne, Vic, Australia
    Mol Psychiatry 12:611, 691-702. 2007
    ....
  39. pmc Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study
    D Sun
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Parkville, Vic, Australia
    Mol Psychiatry 14:976-86. 2009
    ....
  40. doi request reprint Meta-analytic review of neurocognition in bipolar II disorder
    E Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton, Vic, Australia
    Acta Psychiatr Scand 123:165-74. 2011
    ..To examine this issue, we conducted a quantitative review of the cognitive profile of clinically stable patients with BD II in comparison with both patients with BD I and healthy controls...
  41. doi request reprint Corpus callosum shape alterations in individuals prior to the onset of psychosis
    Mark Walterfang
    Melbourne Neuropsychiatry Centre and Department of Psychiatry, University of Melbourne, North Western Mental Health Program, Sunshine Hospital, Melbourne, Australia
    Schizophr Res 103:1-10. 2008
    ..These changes may reflect primary pathology of orbitofrontal and medial frontal cortex, or deficits in anterior interhemispheric myelination...
  42. doi request reprint Insular cortex gray matter changes in individuals at ultra-high-risk of developing psychosis
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 111:94-102. 2009
    ..Whether these longitudinal changes are features of the disorder or related to treatment with antipsychotic medication remains to be determined...
  43. doi request reprint Corpus callosum size and shape in first-episode affective and schizophrenia-spectrum psychosis
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
    Psychiatry Res 173:77-82. 2009
    ..This suggests that schizoaffective disorder may represent two interacting illness processes or be mid-way along a continuum of these two broad categories of illness at first psychosis...
  44. ncbi request reprint Impairments of response conflict monitoring and resolution in schizophrenia
    M Yucel
    Cognitive Neuropsychiatry Research and Academic Unit, Mental Health Research Institute of Victoria, Parkville, Australia
    Psychol Med 32:1251-60. 2002
    ..However, this hypothesis is based on performance on paradigms that require overt or covert shifts of spatial attention...
  45. ncbi request reprint In vivo evidence for early neurodevelopmental anomaly of the anterior cingulate cortex in bipolar disorder
    A Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Vic, Australia
    Acta Psychiatr Scand 116:467-72. 2007
    ..We investigated the evidence for early neurodevelopmental anomalies in the ACC and adjacent paracingulate cortex (PaC) of BD patients by studying cortical folding patterns of the region...
  46. ncbi request reprint Frontostriatal deficits in unipolar major depression
    M A Rogers
    Department of Psychology, Monash University, Clayton, Victoria, Australia
    Brain Res Bull 47:297-310. 1998
    ..It is concluded that, while there is evidence of frontostriatal deficit in major depression, the exact nature of such deficits is uncertain. Issues such as component vs. system dysfunction need to be addressed...
  47. doi request reprint Volumetric MRI study of the insular cortex in individuals with current and past major depression
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria 3053, Australia
    J Affect Disord 121:231-8. 2010
    ..Nevertheless, it remains largely unknown whether MDD patients exhibit morphologic changes of the insular cortex, and whether such changes reflect state or trait markers of the disorder...
  48. doi request reprint Morphology of the corpus callosum at different stages of schizophrenia: cross-sectional study in first-episode and chronic illness
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne North Western Mental Health Program, Sunshine Hospital, Royal Melbourne Hospital, Melbourne corrected
    Br J Psychiatry 192:429-34. 2008
    ..The shape of the corpus callosum may differ in schizophrenia, although no study has compared first-episode with established illness...
  49. ncbi request reprint Follow-up MRI study of the insular cortex in first-episode psychosis and chronic schizophrenia
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 108:49-56. 2009
    ....
  50. ncbi request reprint Individual differences in anterior cingulate/paracingulate morphology are related to executive functions in healthy males
    Alexander Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Sunshine Hospital, 176 Furlong Road, St Albans, Victoria 3021, Australia
    Cereb Cortex 14:424-31. 2004
    ..It therefore appears that normal variations in brain morphology are associated with individual differences in cognitive abilities...
  51. ncbi request reprint Attention deficit hyperactivity disorder: anxiety phenomena in children treated with psychostimulant medication for 6 months or more
    A L Vance
    Maroondah Child and Adolescent Psychiatry Service, Victoria, Australia
    Aust N Z J Psychiatry 33:399-406. 1999
    ..We propose that anxiety will be increased in children with ADHD who are treated with psychostimulant medication in the intermediate- to long-term who are identified by clinicians as poor responders...
  52. ncbi request reprint Abnormal executive function in attention deficit hyperactivity disorder: the effect of stimulant medication and age on spatial working memory
    R Barnett
    Maroondah Hospital Child and Adolescent Mental Health Service, Victoria, Australia
    Psychol Med 31:1107-15. 2001
    ..These deficits were not present in the current sample of children who were receiving psychostimulant medication...
  53. ncbi request reprint Mapping grey matter reductions in schizophrenia: an anatomical likelihood estimation analysis of voxel-based morphometry studies
    A Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 108:104-13. 2009
    ....
  54. ncbi request reprint Incidental radiological findings on brain magnetic resonance imaging in first-episode psychosis and chronic schizophrenia
    D I Lubman
    Cognitive Neuropsychiatry Research and Academic Unit, The University of Melbourne and Sunshine Hospital, Melbourne, Australia
    Acta Psychiatr Scand 106:331-6. 2002
    ..To investigate whether patients with first-episode psychosis or chronic schizophrenia have an increased incidence of magnetic resonance imaging (MRI) brain abnormalities compared with control subjects...
  55. pmc Cognitive impairment in affective psychoses: a meta-analysis
    Emre Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Alan Gilbert Building NNF Level 3, Carlton 3053, Australia
    Schizophr Bull 36:112-25. 2010
    ..In general, the pattern of cognitive impairments in AP was similar to reported findings in euthymic patients with BD, but relatively more pronounced...
  56. doi request reprint Gray matter reduction of the superior temporal gyrus in patients with established bipolar I disorder
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    J Affect Disord 123:276-82. 2010
    ..Functional abnormalities of the superior temporal gyrus (STG) have been implicated in the pathophysiology of bipolar disorder, but magnetic resonance imaging (MRI) studies of this region have yielded inconsistent findings...
  57. doi request reprint Adhesio interthalamica in individuals at high-risk for developing psychosis and patients with psychotic disorders
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 32:1708-14. 2008
    ....
  58. doi request reprint An MRI study of the superior temporal subregions in first-episode patients with various psychotic disorders
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 113:158-66. 2009
    ..Our findings indicate that morphologic abnormalities of the STG gray matter are specific to schizophrenia among various psychotic disorders, implicating its role in the underlying pathophysiology of schizophrenia...
  59. ncbi request reprint Cognitive deficits in youth with familial and clinical high risk to psychosis: a systematic review and meta-analysis
    E Bora
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, Melbourne, Vic, Australia
    Acta Psychiatr Scand 130:1-15. 2014
    ..Studies at-risk adolescents and young adults are likely to provide information about cognitive deficits that predate the onset of the illness...
  60. doi request reprint Evidence of a dimensional relationship between schizotypy and schizophrenia: a systematic review
    M T Nelson
    Melbourne School of Psychological Sciences, The University of Melbourne, Parkville, Victoria, Australia
    Neurosci Biobehav Rev 37:317-27. 2013
    ..Directions for further research are also considered...
  61. doi request reprint Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia
    E Scarr
    Centre for Neuroscience, The University of Melbourne, Parkville, Vic, Australia
    Mol Psychiatry 14:1017-23. 2009
    ....
  62. ncbi request reprint Reduced volume of parietal and frontal association areas in patients with schizophrenia characterized by passivity delusions
    P Maruff
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Sunshine Hospital, St Albans, Melbourne, Australia
    Psychol Med 35:783-9. 2005
    ..Neuropsychological and functional neuroimaging data suggest that passivity delusions are associated with dysfunction of the parietal lobe association cortex...
  63. ncbi request reprint Olfactory impairments in child attention-deficit/hyperactivity disorder
    Felicity R Karsz
    University of Melbourne, Victoria, Australia
    J Clin Psychiatry 69:1462-8. 2008
    ....
  64. pmc Cognitive impairment in schizophrenia and affective psychoses: implications for DSM-V criteria and beyond
    Emre Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Alan Gilbert Building NNF Level 3, Carlton 3053, Australia
    Schizophr Bull 36:36-42. 2010
    ..Given the state of current evidence, these possibilities appear to represent the most parsimonious approaches to the inclusion of cognitive deficits in the diagnostic criteria of schizophrenia and, potentially, of mood disorders...
  65. doi request reprint Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives
    Emre Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Vic, Australia
    J Affect Disord 113:1-20. 2009
    ..Our aim was to delineate neuropsychological deficits related to genetic susceptibility, illness process and iatrogenic factors in bipolar disorder (BD)...
  66. ncbi request reprint A manual and automated MRI study of anterior cingulate and orbito-frontal cortices, and caudate nucleus in obsessive-compulsive disorder: comparison with healthy controls and patients with schizophrenia
    Jem Riffkin
    Melbourne Neuropsychiatry Centre, University of Melbourne and Sunshine Hospital, Melbourne, Victoria, Australia
    Psychiatry Res 138:99-113. 2005
    ..The findings suggest that in contrast to findings in SCZ, there are very few (if any) gross structural anomalies in OCD...
  67. doi request reprint Dopamine modulates neural networks involved in effort-based decision-making
    Seyed M Assadi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Australia
    Neurosci Biobehav Rev 33:383-93. 2009
    ..This is apparently achieved by modulating other neurotransmission systems and by transmitting different signals via D1 vs. D2 receptor subtypes and phasic vs. tonic firing...
  68. ncbi request reprint Early processing deficits in object working memory in first-episode schizophreniform psychosis and established schizophrenia
    Birgit Mathes
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Sunshine Hospital, Melbourne, Australia
    Psychol Med 35:1053-62. 2005
    ..While there are many studies showing working-memory deficits in schizophrenia there are only a few that disentangle impairments for working-memory subprocesses such as perceptual, attentional, mnemonic and executive function...
  69. doi request reprint Anterior cingulate volume in adolescents with first-presentation borderline personality disorder
    Sarah Whittle
    ORYGEN Research Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
    Psychiatry Res 172:155-60. 2009
    ..Longitudinal studies are needed to examine the nature of this abnormality over the course of the disorder...
  70. doi request reprint Cognitive impairment in euthymic major depressive disorder: a meta-analysis
    E Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Vic, Australia
    Psychol Med 43:2017-26. 2013
    ..However, the findings are somewhat inconsistent across the individual studies conducted to date. Our aim was to conduct a systematic review and meta-analysis of existing studies that have examined cognition in euthymic MDD patients...
  71. ncbi request reprint Bimanual coordination in chronic schizophrenia
    M A Bellgrove
    Department of Psychology, Monash University, Clayton, Victoria, Australia
    Brain Cogn 45:325-41. 2001
    ..A disturbance in the ability to switch attention during the out-of-phase task may also be involved...
  72. doi request reprint Pituitary volume and early treatment response in drug-naïve first-episode psychosis patients
    B Garner
    Orygen Youth Health Research Centre, University of Melbourne, Australia
    Schizophr Res 113:65-71. 2009
    ..This study examined whether pituitary volume at the onset of psychosis may be a potential predictor of early treatment response in first-episode psychosis (FEP) patients...
  73. doi request reprint Theory of mind impairment: a distinct trait-marker for schizophrenia spectrum disorders and bipolar disorder?
    E Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Victoria, Australia
    Acta Psychiatr Scand 120:253-64. 2009
    ..The aim of this study was to critically review the literature in order to determine if Theory of Mind (ToM) impairment can be considered a trait-marker for schizophrenia spectrum disorders and bipolar disorder (BD)...
  74. ncbi request reprint The three-syndrome model of schizophrenia: meta-analysis of an artefact
    G W Stuart
    Mental Health Research Institute of Victoria, Parkville, Australia
    Schizophr Res 39:233-42. 1999
    ..It is concluded that the three-syndrome model of schizophrenia is largely an artefact of inadequate measurement at the symptom level...
  75. doi request reprint Grey and white matter abnormalities are associated with impaired spatial working memory ability in first-episode schizophrenia
    Luca Cocchi
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, Melbourne, Australia
    Schizophr Res 115:163-72. 2009
    ....
  76. pmc Modulation of brain resting-state networks by sad mood induction
    Ben J Harrison
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria, Australia
    PLoS ONE 3:e1794. 2008
    ..While these 'resting-state networks' may be relatively enduring phenomena, other evidence suggest that dynamic changes in their functional connectivity may also emerge depending on the brain state of subjects during scanning...
  77. doi request reprint Anatomic abnormalities of the anterior cingulate cortex before psychosis onset: an MRI study of ultra-high-risk individuals
    Alex Fornito
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne, Carlton South, Victoria, Australia
    Biol Psychiatry 64:758-65. 2008
    ..In this study, we characterized prepsychotic ACC abnormalities in a sample of individuals at ultra-high-risk (UHR) for psychosis...
  78. ncbi request reprint Increased duration of illness is associated with reduced volume in right medial temporal/anterior cingulate grey matter in patients with chronic schizophrenia
    Dennis Velakoulis
    Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, University of Melbourne and Sunshine Hospital, St Albans, Australia
    Schizophr Res 57:43-9. 2002
    ..The inverse correlation between right frontal, temporal and cerebellar volumes and the time since the onset of schizophrenia could reflect progressive tissue loss following the first episode of the disorder...
  79. ncbi request reprint Pituitary volume predicts future transition to psychosis in individuals at ultra-high risk of developing psychosis
    Belinda Garner
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Royal Melbourne Hospital, Melbourne, Australia
    Biol Psychiatry 58:417-23. 2005
    ..We examined pituitary volume before the onset of psychosis in subjects who were at ultra-high risk (UHR) for developing psychosis...
  80. doi request reprint Anterior cingulate cortex abnormalities associated with a first psychotic episode in bipolar disorder
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, School of Behavioural Science, University of Melbourne, National Neuroscience Facility, 161 Barry Street, Carlton South, VIC 3053, Australia
    Br J Psychiatry 194:426-33. 2009
    ....
  81. doi request reprint Medial temporal lobe glutathione concentration in first episode psychosis: a 1H-MRS investigation
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Australia
    Neurobiol Dis 33:354-7. 2009
    ..This study provides further evidence of significant perturbations in brain GSH in first episode psychosis, and supports a broader involvement of GSH in the pathophysiology of schizophrenia...
  82. pmc Progressive brain structural changes mapped as psychosis develops in 'at risk' individuals
    Daqiang Sun
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Parkville, Victoria, Australia
    Schizophr Res 108:85-92. 2009
    ..We hypothesized that progressive volume loss occurs in prefrontal regions during the transition to psychosis...
  83. doi request reprint Altered corticostriatal functional connectivity in obsessive-compulsive disorder
    Ben J Harrison
    Institut d Alta Tecnologia Parc de Recerca Biomèdica de Barcelona, Centro Radiológico Computerizado Corporació Sanitària, Barcelona, Spain
    Arch Gen Psychiatry 66:1189-200. 2009
    ..Although neuroimaging studies of patients have supported this network model of OCD, very few have applied measurements that are sensitive to brain connectivity features...
  84. doi request reprint Regional brain abnormalities associated with long-term heavy cannabis use
    Murat Yucel
    MAPS, ORYGEN Research Centre, 35 Poplar Rd, Melbourne, Victoria, Australia
    Arch Gen Psychiatry 65:694-701. 2008
    ..Cannabis is the most widely used illicit drug in the developed world. Despite this, there is a paucity of research examining its long-term effect on the human brain...
  85. doi request reprint Whole-brain anatomical networks: does the choice of nodes matter?
    Andrew Zalesky
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
    Neuroimage 50:970-83. 2010
    ..9 vs. sigma(4000)=53.6+/-2.2). These findings indicate that any comparison of network parameters across studies must be made with reference to the spatial scale of the nodal parcellation...
  86. ncbi request reprint Surface-based morphometry of the anterior cingulate cortex in first episode schizophrenia
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Australia
    Hum Brain Mapp 29:478-89. 2008
    ....
  87. doi request reprint Orbitofrontal, amygdala and hippocampal volumes in teenagers with first-presentation borderline personality disorder
    Andrew M Chanen
    ORYGEN Research Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
    Psychiatry Res 163:116-25. 2008
    ..Hippocampal and amygdala volume reductions observed in adult BPD samples might develop during the course of the disorder, although longitudinal studies are needed to examine this...
  88. ncbi request reprint Implications of lipid biology for the pathogenesis of schizophrenia
    Gregor E Berger
    Early Psychosis Prevention and Intervention Centre, MH SKY EPPIC, Victoria
    Aust N Z J Psychiatry 36:355-66. 2002
    ..Both aspects are proposed as being important in the pathogenesis of schizophrenia. The purpose of this paper is to examine the implications of lipid biology, in particular the role of essential fatty acids (EFA), for schizophrenia...
  89. ncbi request reprint Memory impairments identified in people at ultra-high risk for psychosis who later develop first-episode psychosis
    Warrick J Brewer
    ORYGEN Research Centre, Melbourne, Australia
    Am J Psychiatry 162:71-8. 2005
    ..While cognitive deficits are frequently reported in psychotic disorders, it is unclear whether these impairments predate the onset of illness and to what extent they are predictive of later transition to psychosis...
  90. ncbi request reprint Non-reduction in hippocampal volume is associated with higher risk of psychosis
    Lisa J Phillips
    PACE Clinic, Department of Psychiatry, University of Melbourne, 35 Poplar Road, Victoria 3052, Parkville, Australia
    Schizophr Res 58:145-58. 2002
    ..Alternatively, selection factors associated with the UHR cohort may have created a bias in the results. Replication of these results is required in other high-risk cohorts...
  91. doi request reprint Hoarding behaviors in children with learning disabilities
    Renee Testa
    Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, Australia
    J Child Neurol 26:574-9. 2011
    ..It is unclear whether underlying cognitive features may play a major role in the development of hoarding behaviors in children with learning disabilities...
  92. pmc White-matter abnormalities in adolescents with long-term inhalant and cannabis use: a diffusion magnetic resonance imaging study
    Murat Yucel
    Orygen Youth Health Research Centre, 35 Poplar Rd, Parkville, Victoria 3052, Australia
    J Psychiatry Neurosci 35:409-12. 2010
    ....
  93. ncbi request reprint From neuroprogression to neuroprotection: implications for clinical care
    Michael Berk
    Department of Clinical and Biomedical Sciences Barwon Health, University of Melbourne, Melbourne, Vic
    Med J Aust 193:S36-40. 2010
    ..These developments need to be combined with service initiatives to maximise the opportunities for early diagnosis and intervention...
  94. doi request reprint Anatomical abnormalities of the anterior cingulate and paracingulate cortex in patients with bipolar I disorder
    Alex Fornito
    Melbourne Neuropsychiatry Centre, The University of Melbourne, Melbourne, Australia
    Psychiatry Res 162:123-32. 2008
    ..These findings suggest that bipolar disorder is associated with more pronounced changes in the PaC, and that reliance on volumetric measures alone may obscure more subtle differences...
  95. doi request reprint Anterior cingulate glutamate-glutamine levels predict symptom severity in women with obsessive-compulsive disorder
    Murat Yucel
    Melbourne Neuropsychiatry Centre, National Neuroscience Facility, Carlton South, Australia
    Aust N Z J Psychiatry 42:467-77. 2008
    ..The purpose of the present study was to investigate how ACC biochemistry in OCD varies as a function of gender, hemisphere, subregion, and symptomatology...
  96. doi request reprint Voxelwise meta-analysis of gray matter abnormalities in bipolar disorder
    Emre Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia
    Biol Psychiatry 67:1097-105. 2010
    ..We conducted a meta-analysis of gray matter abnormalities in bipolar disorder (BD) using voxel-based morphometry studies to help clarify the structural abnormalities underpinning this condition...
  97. ncbi request reprint Increased prefrontal cerebral blood flow in first-episode schizophrenia following treatment: longitudinal positron emission tomography study
    Warrick J Brewer
    ORYGEN Research Centre, Locked Bag 10, Parkville, VIC 3052, Australia and Early Psychosis Prevention and Intervention Centre, Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia
    Aust N Z J Psychiatry 41:129-35. 2007
    ..The objective of the current study was to investigate executive-control related neural activity from first onset of the illness through to symptom stabilization...
  98. pmc Anatomical abnormalities of the anterior cingulate cortex in schizophrenia: bridging the gap between neuroimaging and neuropathology
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia
    Schizophr Bull 35:973-93. 2009
    ..We discuss the potential mechanisms that might facilitate integration of these findings and consider strategies for future research...
  99. ncbi request reprint Clinical staging: a heuristic model for psychiatry and youth mental health
    Patrick D McGorry
    University of Melbourne, Melbourne, Vic, Australia
    Med J Aust 187:S40-2. 2007
    ..Young people with emerging mental and substance use disorders could be the main beneficiaries...
  100. doi request reprint Neuroprotective effects of ethyl-eicosapentaenoic acid in first episode psychosis: a longitudinal T2 relaxometry pilot study
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, University of Melbourne, Australia
    Psychiatry Res 182:180-2. 2010
    ..There was an increase in T(2) in the placebo group but not in the E-EPA group, suggesting a neuroprotective effect of E-EPA treatment. In addition, the smaller the increase in T(2), the greater the improvement in negative symptoms...