R J Norman

Summary

Affiliation: University of Adelaide
Country: Australia

Publications

  1. pmc PPAR Gamma: Coordinating Metabolic and Immune Contributions to Female Fertility
    Cadence E Minge
    Research Centre for Reproductive Health, School of Paediatrics and Reproductive Health, The University of Adelaide, South Australia 5005, Australia
    PPAR Res 2008:243791. 2008
  2. pmc Acupuncture to improve live birth rates for women undergoing in vitro fertilization: a protocol for a randomized controlled trial
    Caroline A Smith
    Centre for Complementary Medicine Research, University of Western Sydney, Locked Bag, 1797, Penrith South, DC, NSW 2751, Australia
    Trials 13:60. 2012
  3. ncbi request reprint Obesity, polycystic ovary syndrome and anovulation--how are they interrelated?
    R J Norman
    Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia, Australia
    Curr Opin Obstet Gynecol 13:323-7. 2001
  4. ncbi request reprint 4: Polycystic ovary syndrome
    Robert J Norman
    Adelaide University, Reproductive Medicine Unit, The Queen Elizabeth Hospital, SA
    Med J Aust 180:132-7. 2004
  5. ncbi request reprint Effects of obesity on assisted reproductive technology outcomes
    Robert J Norman
    Research Centre for Reproductive Health, School of Paediatrics and Reproductive Health, University of Adelaide, South Australia, Australia
    Fertil Steril 89:1611-2. 2008
  6. ncbi request reprint Hyperandrogenaemia and the ovary
    Robert J Norman
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville Road, Woodville, Australia
    Mol Cell Endocrinol 191:113-9. 2002
  7. ncbi request reprint Lifestyle choices, diet, and insulin sensitizers in polycystic ovary syndrome
    R J Norman
    Department of Obstetrics and Gynaecology, Research Centre for Reproductive Health, University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
    Endocrine 30:35-43. 2006
  8. ncbi request reprint The role of lifestyle modification in polycystic ovary syndrome
    Robert J Norman
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville, South Australia, 5011, Australia
    Trends Endocrinol Metab 13:251-7. 2002
  9. ncbi request reprint Recombinant or urinary gonadotrophins - an Australian perspective
    R J Norman
    Research Centre for Reproductive Health, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA
    Reprod Biomed Online 11:542-3. 2005
  10. ncbi request reprint Should we continue or stop insulin sensitizing drugs during pregnancy?
    Robert J Norman
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia, Australia
    Curr Opin Obstet Gynecol 16:245-50. 2004

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. pmc PPAR Gamma: Coordinating Metabolic and Immune Contributions to Female Fertility
    Cadence E Minge
    Research Centre for Reproductive Health, School of Paediatrics and Reproductive Health, The University of Adelaide, South Australia 5005, Australia
    PPAR Res 2008:243791. 2008
    ..This review discusses the developing links between PPARG activity and female reproductive function, and highlights several mechanisms that may facilitate such a relationship...
  2. pmc Acupuncture to improve live birth rates for women undergoing in vitro fertilization: a protocol for a randomized controlled trial
    Caroline A Smith
    Centre for Complementary Medicine Research, University of Western Sydney, Locked Bag, 1797, Penrith South, DC, NSW 2751, Australia
    Trials 13:60. 2012
    ....
  3. ncbi request reprint Obesity, polycystic ovary syndrome and anovulation--how are they interrelated?
    R J Norman
    Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia, Australia
    Curr Opin Obstet Gynecol 13:323-7. 2001
    ..This review looks at the latest advances in understanding polycystic ovary syndrome, particularly in obesity...
  4. ncbi request reprint 4: Polycystic ovary syndrome
    Robert J Norman
    Adelaide University, Reproductive Medicine Unit, The Queen Elizabeth Hospital, SA
    Med J Aust 180:132-7. 2004
    ....
  5. ncbi request reprint Effects of obesity on assisted reproductive technology outcomes
    Robert J Norman
    Research Centre for Reproductive Health, School of Paediatrics and Reproductive Health, University of Adelaide, South Australia, Australia
    Fertil Steril 89:1611-2. 2008
    ..Several studies have sought to determine the effects of obesity on the endometrium by analyzing outcomes in patients receiving ovum donation...
  6. ncbi request reprint Hyperandrogenaemia and the ovary
    Robert J Norman
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville Road, Woodville, Australia
    Mol Cell Endocrinol 191:113-9. 2002
    ..Interventions include approaches that target both these hormones as well as the ovary itself...
  7. ncbi request reprint Lifestyle choices, diet, and insulin sensitizers in polycystic ovary syndrome
    R J Norman
    Department of Obstetrics and Gynaecology, Research Centre for Reproductive Health, University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
    Endocrine 30:35-43. 2006
    ..Lifestyle choices should be discussed in this group of patients. The role of insulin sensitizers, including metformin, has still to be determined in this condition...
  8. ncbi request reprint The role of lifestyle modification in polycystic ovary syndrome
    Robert J Norman
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville, South Australia, 5011, Australia
    Trends Endocrinol Metab 13:251-7. 2002
    ..Modifying additional lifestyle factors, including alcohol consumption, psychosocial stressors and smoking, are also crucial in long-term treatment of PCOS...
  9. ncbi request reprint Recombinant or urinary gonadotrophins - an Australian perspective
    R J Norman
    Research Centre for Reproductive Health, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA
    Reprod Biomed Online 11:542-3. 2005
    ..The Australian experience of gonadotrophin stimulation is a useful example of steps that lead to a country deciding to use recombinant FSH solely...
  10. ncbi request reprint Should we continue or stop insulin sensitizing drugs during pregnancy?
    Robert J Norman
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia, Australia
    Curr Opin Obstet Gynecol 16:245-50. 2004
    ..There has also been an interest in the use of metformin for gestational diabetes. However, administration of metformin to prevent miscarriage is controversial and widespread use of this drug in early pregnancy requires investigation...
  11. ncbi request reprint The potential danger of COX-2 inhibitors
    Robert J Norman
    Department of Obstetrics and Gynecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia, Australia
    Fertil Steril 81:493-4. 2004
    ..Women attempting to become pregnant need to pay more attention to their use of COX-2 inhibitors...
  12. ncbi request reprint Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome
    R J Norman
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville Road, Woodville, South Australia 5011, Australia
    Hum Reprod 16:1995-8. 2001
    ..However, little is known about the change in glucose tolerance that occurs over a period of several years in women with PCOS...
  13. ncbi request reprint Circulating follistatin concentrations are higher and activin concentrations are lower in polycystic ovarian syndrome
    R J Norman
    Reproductive Medicine Unit, The Queen Elizabeth Hospital, University of Adelaide, 28 Woodville Road, Woodville, South Australia 5011, Australia
    Hum Reprod 16:668-72. 2001
    ....
  14. ncbi request reprint Androgens augment the mitogenic effects of oocyte-secreted factors and growth differentiation factor 9 on porcine granulosa cells
    T E Hickey
    Research Centre for Reproductive Health, Department of Obstetrics and Gynaecology, University of Adelaide, Woodville, South Australia
    Biol Reprod 73:825-32. 2005
    ..These signaling pathways are likely to be important regulators of folliculogenesis in vivo, and may contribute to the excess follicle growth that is observed in androgen-treated female animals...
  15. ncbi request reprint Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition
    L J Moran
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, Adelaide, South Australia 5000, Australia
    J Clin Endocrinol Metab 89:3337-44. 2004
    ..001) and more hungry (P = 0.007) after a test meal at wk 0 and 16 than subjects without PCOS. Appetite regulation, as measured by subjective short-term hunger and satiety and ghrelin homeostasis, may be impaired in PCOS...
  16. ncbi request reprint Luteal function associated with single, multiple and ectopic embryo implantation in natural cycles or after ovarian hyperstimulation for in-vitro fertilization/gamete intra-fallopian transfer
    L Wang
    Department of Obstetrics and Gynaecology, University of Adelaide, South Australia
    Hum Reprod 5:476-80. 1990
    ..01). Ectopic implantation (n = 11) had the lowest progesterone concentrations on day 11 (P less than 0.01) and this may imply a delay in corpus luteum rescue or a later implantation time than intrauterine conception...
  17. doi request reprint The effect of obesity on polycystic ovary syndrome: a systematic review and meta-analysis
    S S Lim
    The Robinson Institute, University of Adelaide, Adelaide, South Australia, Australia
    Obes Rev 14:95-109. 2013
    ..Central obesity was associated with higher fasting insulin levels. These results suggest that prevention and treatment of obesity is important for the management of PCOS...
  18. doi request reprint The effect of comprehensive lifestyle intervention or metformin on obesity in young women
    S S Lim
    Discipline of Physiology, School of Molecular and Biomedical Science, Adelaide University, SA 5000, Australia
    Nutr Metab Cardiovasc Dis 21:261-8. 2011
    ....
  19. ncbi request reprint Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome
    L J Moran
    Reproductive Medicine Unit, Department of Obstetrics and Gynecology, University of Adelaide, Queen Elizabeth Hospital, Woodville, South Australia 5011, Australia
    J Clin Endocrinol Metab 88:812-9. 2003
    ..An HP weight loss diet may result in minor differential endocrine and metabolic improvements...
  20. ncbi request reprint Effects of leptin administration and feed restriction on thecal leucocytes in the preovulatory rat ovary and the effects of leptin on meiotic maturation, granulosa cell proliferation, steroid hormone and PGE2 release in cultured rat ovarian follicles
    P S Duggal
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville 5011, SA, Australia
    Reproduction 123:891-8. 2002
    ..In summary, leptin does not appear to have an adverse effect on the components of ovulation tested in this study, and therefore must impact on the ovulatory cascade in a way that remains to be defined...
  21. ncbi request reprint Polycystic ovarian syndrome and the risk of spontaneous abortion following assisted reproductive technology treatment
    J X Wang
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
    Hum Reprod 16:2606-9. 2001
    ..This study aims to determine the effect of PCOS status on the risk of spontaneous abortion with adjustment for body mass and several other confounding factors in a large cohort of pregnant infertile women...
  22. ncbi request reprint Expression of the long (OB-RB) and short (OB-RA) forms of the leptin receptor throughout the oestrous cycle in the mature rat ovary
    P S Duggal
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville 5011, SA, Australia
    Reproduction 123:899-905. 2002
    ..This research supports the initial hypothesis and shows that ovarian leptin receptor concentrations vary throughout the oestrous cycle in response to the changing environment of the ovary...
  23. ncbi request reprint Decrease in luteal gonadotropin concentration in conception cycles after in vitro fertilization/gamete intrafallopian transfer
    R J Norman
    Reproductive Medicine Unit, Queen Elizabeth Hospital, Woodville, South Australia
    Fertil Steril 55:125-30. 1991
    ..It is concluded that suppression of LH and FSH in hyperstimulated pregnancy cycles occurs after the time of the rising human chorionic gonadotropin concentrations in plasma...
  24. ncbi request reprint Interactions between androgen and growth factors in granulosa cell subtypes of porcine antral follicles
    T E Hickey
    Department of Obstetrics and Gynaecology, Reproductive Medicine Unit, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia 5011, Australia
    Biol Reprod 71:45-52. 2004
    ....
  25. ncbi request reprint Obesity and reproductive disorders: a review
    R J Norman
    Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA, Australia
    Reprod Fertil Dev 10:55-63. 1998
    ..Results indicate that fertility is improved through exercise and sensible eating patterns when conducted in a group environment. The mechanisms for this are unclear but may be associated with changes in sensitivity to insulin...
  26. ncbi request reprint Adipokines: implications for female fertility and obesity
    M Mitchell
    Research Centre for Reproductive Health, Department of Obstetrics and Gynaecology, The University of Adelaide, Australia, 5011
    Reproduction 130:583-97. 2005
    ..In this review such biological actions and potential roles of the adipokines leptin, adiponectin and resistin are explored in relation to female fertility and the complexity of the obese metabolic state...
  27. ncbi request reprint Dietary effects on fertility treatment and pregnancy outcomes
    Siew S Lim
    Discipline of Physiology, Adelaide University, Adelaide, Australia
    Curr Opin Endocrinol Diabetes Obes 14:465-9. 2007
    ..We summarize the dietary modifications that optimize fertility treatment outcomes...
  28. ncbi request reprint The use of anti-mullerian hormone in predicting menstrual response after weight loss in overweight women with polycystic ovary syndrome
    Lisa J Moran
    Research Centre for Reproductive Health, Discipline of Obstetrics and Gynaecology, University of Adelaide, 6th Floor, Medical School North, Adelaide SA 5005, Australia
    J Clin Endocrinol Metab 92:3796-802. 2007
    ....
  29. ncbi request reprint Comparison of aerobic exercise capacity and muscle strength in overweight women with and without polycystic ovary syndrome
    R L Thomson
    Australian Technology Network Centre for Metabolic Fitness, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia
    BJOG 116:1242-50. 2009
    ..To assess maximal aerobic capacity (VO2max) and muscle strength in overweight and obese women with polycystic ovary syndrome (PCOS) and determine their relationship with metabolic and hormonal factors...
  30. ncbi request reprint Granulocyte-macrophage colony-stimulating factor promotes glucose transport and blastomere viability in murine preimplantation embryos
    S A Robertson
    Department of Obstetrics and Gynaecology, University of Adelaide, Adelaide 5005, Australia
    Biol Reprod 64:1206-15. 2001
    ....
  31. doi request reprint Overweight, obesity and central obesity in women with polycystic ovary syndrome: a systematic review and meta-analysis
    S S Lim
    The Robinson Institute, University of Adelaide, Adelaide, Australia
    Hum Reprod Update 18:618-37. 2012
    ..Clinical management of PCOS should include the prevention and management of overweight and obesity...
  32. ncbi request reprint Metformin and intervention in polycystic ovary syndrome. Endocrine Society of Australia, the Australian Diabetes Society and the Australian Paediatric Endocrine Group
    R J Norman
    Department of Obstetrics and Gynaecology, University of Adelaide, SA
    Med J Aust 174:580-3. 2001
    ..Further properly planned randomised controlled trials are required...
  33. ncbi request reprint The obese patient with infertility: a practical approach to diagnosis and treatment
    L J Moran
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, South Australia, Australia
    Nutr Clin Care 5:290-7. 2002
    ..Adoption of these principles in a primary healthcare setting can therefore aid in treatment of infertility related to obesity...
  34. ncbi request reprint Gamete intra-fallopian transfer: outcome following the elective or non-elective replacement of two, three or four oocytes
    X J Wang
    Department of Obstetrics and Gynaecology, University of Adelaide, South Australia
    Hum Reprod 8:1231-4. 1993
    ....
  35. doi request reprint Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone reverses the adverse effects of diet-induced obesity on oocyte quality
    Cadence E Minge
    School of Paediatrics and Reproductive Health, Discipline of Obstetrics and Gynaecology, The University of Adelaide, Adelaide, South Australia 5005, Australia
    Endocrinology 149:2646-56. 2008
    ..Improved blastocyst quality in obese females treated with rosiglitazone before mating indicates that peroxisome proliferator activated receptor-gamma is a key target for metabolic regulation of ovarian function and oocyte quality...
  36. ncbi request reprint C-reactive protein before and after weight loss in overweight women with and without polycystic ovary syndrome
    Lisa J Moran
    Research Centre for Reproductive Health, University of Adelaide, South Australia 5000, Australia
    J Clin Endocrinol Metab 92:2944-51. 2007
    ..Polycystic ovary syndrome (PCOS) is associated with reproductive and metabolic abnormalities. It is unknown whether overweight women with and without PCOS achieve similar benefits from weight loss for cardiovascular risk factors...
  37. ncbi request reprint Understanding and managing disturbances in insulin metabolism and body weight in women with polycystic ovary syndrome
    L Moran
    Department of Obstetrics and Gynaecology, CSIRO Human Nutrition, Kintore Avenue, Adelaide, Australia
    Best Pract Res Clin Obstet Gynaecol 18:719-36. 2004
    ..It is vital that the efficacy of these strategies is assessed so that accurate medical and dietetic advice can be given both to patients and to the health-care community...
  38. doi request reprint Clinical, ultrasound and biochemical features of polycystic ovary syndrome in adolescents: implications for diagnosis
    M Hickey
    Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Vic, Australia
    Hum Reprod 26:1469-77. 2011
    ..The prevalence of clinical, ultrasound and biochemical features of PCOS in a community-based adolescent population using current diagnostic criteria has not previously been described...
  39. ncbi request reprint Effect of granulocyte-macrophage colony-stimulating factor deficiency on ovarian follicular cell function
    R B Gilchrist
    The Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
    J Reprod Fertil 120:283-92. 2000
    ....
  40. ncbi request reprint The leuprolide flare regime for in-vitro fertilization/gamete intra-fallopian transfer and embryo cryopreservation
    C D Matthews
    Department of Obstetrics and Gynaecology, University of Adelaide, Queen Elizabeth Hospital, South Australia
    Hum Reprod 6:817-22. 1991
    ..The flare protocol appears to be a satisfactory choice for the majority of subjects but careful monitoring is required to avoid the potential for ovarian hyperstimulation...
  41. ncbi request reprint Psychological effects of prescriptive vs general lifestyle advice for weight loss in young women
    Siew S Lim
    Discipline of Physiology, School of Molecular and Biomedical Science, Adelaide University, Adelaide, South Australia, Australia
    J Am Diet Assoc 109:1917-21. 2009
    ..However, these quantitative targets should be accompanied with qualitative advice on how they could be met in a variety of circumstances...
  42. doi request reprint Sex hormone binding globulin, but not testosterone, is associated with the metabolic syndrome in overweight and obese women with polycystic ovary syndrome
    L J Moran
    The Robinson Institute, University of Adelaide, North Adelaide, Australia
    J Endocrinol Invest 36:1004-10. 2013
    ..Decreased SHBG and elevated testosterone are associated with metabolic syndrome and glucose intolerance in women...
  43. ncbi request reprint The effect of intercourse on pregnancy rates during assisted human reproduction
    K P Tremellen
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, South Australia, Australia
    Hum Reprod 15:2653-8. 2000
    ..036, odds ratio 1.48, 95% confidence interval 1.01-2.19). Hence exposure to semen around the time of embryo transfer increases the likelihood of successful early embryo implantation and development...
  44. ncbi request reprint Luteinizing hormone/chorionic gonadotropin bioactivity in the common marmoset (Callithrix jacchus) is due to a chorionic gonadotropin molecule with a structure intermediate between human chorionic gonadotropin and human luteinizing hormone
    A P Simula
    Department of Obstetrics and Gynaecology, University of Adelaide, Queen Elizabeth Hospital, Australia
    Biol Reprod 53:380-9. 1995
    ..This suggests that the LH/CG bioactivity reported from marmoset placentae and embryos is due to a molecule with structural features common to hLH (glycosylation pattern) and hCG (CG beta C-terminal structure)...
  45. ncbi request reprint What should we do with donated embryos that may be genetically affected?
    Sheryl de Lacey
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, Adelaide, South Australia, 5005
    Hum Reprod 19:1065-8. 2004
    ..The ethical and legal issues arising from genetic screening in embryo donation are discussed in relation to two recent cases where embryos with uncertain genetic health were offered for donation...
  46. ncbi request reprint Soluble adhesion molecules in serum throughout the menstrual cycle
    Nigel Bonello
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
    Hum Reprod 17:2272-8. 2002
    ....
  47. ncbi request reprint Reducing multiple pregnancy from assisted reproduction treatment: educating patients and medical staff
    Jim Wang
    Research Centre for Reproductive Health, Department of Obstetrics and Gynaecology, University of Adelaide, Queen Elizabeth Hospital, Woodville Road, Adelaide, SA 5011, Australia
    Med J Aust 184:180-1. 2006
    ..Many patients and some clinicians remain to be convinced that SET is a better clinical option. Adequate education, based on available evidence, is one important way to promote the use of SET...
  48. ncbi request reprint Influence of acupuncture stimulation on pregnancy rates for women undergoing embryo transfer
    Caroline Smith
    School of Health Science, The University of South Australia, South Australia, Australia
    Fertil Steril 85:1352-8. 2006
    ..To evaluate the effects of acupuncture on clinical pregnancy rates for women undergoing ET...
  49. ncbi request reprint Effect of a very-low-calorie diet on in vitro fertilization outcomes
    Victoria Tsagareli
    The University of Adelaide, Research Centre for Reproductive Health, Faculty of Health Sciences, Department of Obstetrics and Gynaecology, Adelaide, Australia
    Fertil Steril 86:227-9. 2006
    ..A low-calorie diet in a group of overweight or obese patients for a short period before and during IVF results in variable tolerance to the dietary regime and an unsatisfactory IVF outcome...
  50. ncbi request reprint Impact of obesity on female fertility and fertility treatment
    Murizah M Zain
    University of Adelaide, Research Centre for Reproductive Health, School of Paediatrics and Reproductive Health, South Australia, Australia
    Womens Health (Lond Engl) 4:183-94. 2008
    ..While various strategies for weight reduction, including diet, exercise, pharmacological and surgical intervention exist, lifestyle modification continues to be of paramount importance...
  51. ncbi request reprint Obesity increases the risk of spontaneous abortion during infertility treatment
    Jim X Wang
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, Australia
    Obes Res 10:551-4. 2002
    ..This study examines the relationship between body mass and the risk of spontaneous abortion in a large cohort of patients who received infertility treatment...
  52. doi request reprint Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects
    Sharmalar Rajendran
    Cardiology Unit, The Basil Hetzel Institute, The Queen Elizabeth Hospital, Department of Medicine, The University of Adelaide, Australia
    Atherosclerosis 204:509-14. 2009
    ..We conclude that in PCOS subjects, independent of obesity and associated insulin resistance, profound and reproducible impairment of platelet responsiveness to NO is an additional component of cardiovascular homeostatic disturbance...
  53. doi request reprint Obese women exhibit differences in ovarian metabolites, hormones, and gene expression compared with moderate-weight women
    Rebecca L Robker
    The Robinson Institute, School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, South Australia, 5005 Australia
    J Clin Endocrinol Metab 94:1533-40. 2009
    ..Obese women experience longer times to conception, even if they are young and cycling regularly, which is suggestive of alterations in ovarian function during the periconceptual period...
  54. ncbi request reprint Programming and reproductive functioning
    Michael J Davies
    Reproductive Medicine Unit, Dept Obstetrics and Gynaecology, University of Adelaide, 5005, Adelaide, Australia
    Trends Endocrinol Metab 13:386-92. 2002
    ....
  55. ncbi request reprint Towards less confusing terminology in reproductive medicine: clarifying medical ambiguities to the benefit of all
    Michael J Davies
    Research Centre for Reproductive Health, Department of Obstetrics and Gynaecology, University of Adelaide, Australia
    Hum Reprod 20:2669-71. 2005
    ..Unpacking the meaning of the term 'infertility' reveals a complex of interdependent concepts that are both social and biological in origin...
  56. ncbi request reprint Single or multiple embryo transfer following in vitro fertilisation for improved neonatal outcome: a systematic review of the literature
    Marianna R Dare
    Department of Obstetrics and Gynaecology, University of Adelaide, Women s and Children s Hospital, North Adelaide, South Australia, Australia
    Aust N Z J Obstet Gynaecol 44:283-91. 2004
    ....
  57. ncbi request reprint Effects of lifestyle modification in polycystic ovarian syndrome
    Lisa J Moran
    CSIRO Human Nutrition, PO Box 10041 BC, Adelaide, South Australia, Australia, 5000
    Reprod Biomed Online 12:569-78. 2006
    ..However, the literature on effective diet and exercise programmes for PCOS has been sparse, and structured advice for implementing components of lifestyle modification programmes should be assessed in this population...
  58. ncbi request reprint Periovulatory expression of intercellular adhesion molecule-1 in the rat ovary
    Nigel Bonello
    Research Centre for Reproductive Health, Department of Obstetrics and Gynaecology, University of Adelaide, Queen Elizabeth Hospital, Woodville, South Australia 5011, Australia
    Biol Reprod 71:1384-90. 2004
    ..Taken together, these findings suggest rat ovarian ICAM-1 may be instrumental in the active recruitment of leukocytes into the preovulatory ovary and may have a role in corpus luteum formation...
  59. ncbi request reprint What is the most relevant standard of success in assisted reproduction? Assessing the BESST index for reproduction treatment
    Michael J Davies
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, Adelaide, Australia
    Hum Reprod 19:1049-51. 2004
    ..A modified BESST index, not including cycles of initiated treatment as a denominator, indicated that the ART births contained a substantially lower proportion of BESST babies when compared to the entire population of births...
  60. ncbi request reprint Incidence of spontaneous abortion among pregnancies produced by assisted reproductive technology
    Jim X Wang
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA, Australia 5011
    Hum Reprod 19:272-7. 2004
    ....
  61. ncbi request reprint Risk factors for the deterioration of glucose metabolism in polycystic ovary syndrome
    Jim X Wang
    Repromed, Research Centre for Reproductive Health, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, Australia 5011
    Reprod Biomed Online 9:201-4. 2004
    ..Moderate weight gain has no significant detrimental effect on the rate of deterioration of glucose metabolism...
  62. ncbi request reprint Impact of menstrual cycle phase on the exercise status of young, sedentary women
    Leanne M Redman
    Department of Physiology, University of Adelaide, 5005, Australia
    Eur J Appl Physiol 90:505-13. 2003
    ....
  63. ncbi request reprint Preimplantation genetic diagnosis for beta-thalassaemia using sequencing of single cell PCR products to detect mutations and polymorphic loci
    Nicole D Hussey
    Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, 5011, South Australia, Australia
    Mol Hum Reprod 8:1136-43. 2002
    ..We present here the data from eight clinical PGD cycles for three couples resulting in a singleton pregnancy and a twin pregnancy with all babies confirmed to be free from beta-thalassaemia (major)...
  64. doi request reprint Determinants of insulin responsiveness in young women: Impact of polycystic ovarian syndrome, nitric oxide, and vitamin D
    D T M Ngo
    Vascular Disease and Therapeutics Research Group, Basil Hetzel Institute, The Queen Elizabeth Hospital, Department of Medicine, The University of Adelaide, Australia
    Nitric Oxide 25:326-30. 2011
    ..We sought to evaluate whether the impact of other factors potentially associated both with PCOS and with IR might differentially modulate degree of IR in women with and without PCOS...
  65. doi request reprint Power Doppler assessment of follicle vascularity at the time of oocyte retrieval in in vitro fertilization cycles
    Stephen J Robson
    Department of Obstetrics and Gynaecology, Australian National University, Canberra Hospital, Canberra, Australia
    Fertil Steril 90:2179-82. 2008
    ..To assess the practicality of using power Doppler (PD) to assess follicular vascularity at the time of oocyte retrieval...
  66. ncbi request reprint Postprandial ghrelin, cholecystokinin, peptide YY, and appetite before and after weight loss in overweight women with and without polycystic ovary syndrome
    Lisa J Moran
    Research Centre for Reproductive Health, Discipline of Obstetrics and Gynaecology, University of Adelaide, Adelaide, Australia
    Am J Clin Nutr 86:1603-10. 2007
    ..Polycystic ovary syndrome (PCOS) is a common condition associated with obesity and with reproductive and metabolic dysfunction. Abnormalities in appetite regulation in PCOS patients may contribute to difficulties in weight management...
  67. doi request reprint Androgens and polycystic ovary syndrome
    Vicki Nisenblat
    Robinson Institute, School of Pediatrics and Reproductive Health, University of Adelaide, South Australia, Australia
    Curr Opin Endocrinol Diabetes Obes 16:224-31. 2009
    ..This review focuses on androgen biosynthesis, use, metabolism in PCOS and clinical consequences of hyperandrogenism...
  68. ncbi request reprint Polycystic ovary syndrome
    Robert J Norman
    Research Centre for Reproductive Health, School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, South Australia, Australia
    Lancet 370:685-97. 2007
    ..The cause of polycystic ovary syndrome is unknown, but studies suggest a strong genetic component that is affected by gestational environment, lifestyle factors, or both...
  69. ncbi request reprint Macrophage contributions to ovarian function
    Ruijin Wu
    Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville Road, Woodville, South Australia 5011
    Hum Reprod Update 10:119-33. 2004
    ....
  70. ncbi request reprint Short-term meal replacements followed by dietary macronutrient restriction enhance weight loss in polycystic ovary syndrome
    Lisa J Moran
    Discipline of Obstetrics and Gynaecology Research Centre for Reproductive Health, School of Paediatrics and Reproductive Health, Adelaide, Australia
    Am J Clin Nutr 84:77-87. 2006
    ..Polycystic ovary syndrome (PCOS), a common condition in women, improves with weight loss. Meal replacements in short-term weight loss and strategies for weight maintenance have not been investigated in PCOS...
  71. ncbi request reprint The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria
    Wendy A March
    Discipline of Obstetrics Gynaecology, Robinson Institute, The University of Adelaide, Adelaide, SA 5005, Australia
    Hum Reprod 25:544-51. 2010
    ....
  72. doi request reprint High-fat diet causes lipotoxicity responses in cumulus-oocyte complexes and decreased fertilization rates
    Linda Lin Yan Wu
    School of Pediatrics and Reproductive Health, Robinson Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
    Endocrinology 151:5438-45. 2010
    ..These results indicate that lipotoxicity may be occurring in ovarian cells of obese women and may contribute to the reduced pregnancy rates observed in response to obesity...
  73. ncbi request reprint Epigenetic modification of the X chromosome influences susceptibility to polycystic ovary syndrome
    T E Hickey
    Department of Obstetrics and Gynaecology, University of Adelaide, 1st Floor Maternity Building, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville, South Australia 5011, Australia
    J Clin Endocrinol Metab 91:2789-91. 2006
    ..Some genetic studies have suggested the involvement of X-linked genes in PCOS, but the influence of X chromosome inactivation (XCI) on manifestation of this disorder has not previously been examined...
  74. ncbi request reprint hCGbeta core fragment is a metabolite of hCG: evidence from infusion of recombinant hCG
    R J Norman
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Adelaide, South Austrailia 5011, Australia
    J Endocrinol 164:299-305. 2000
    ..The molar ratio of hCGbetacf to hCG in urine increased from 3.1+/-1.7%, on day 1, to 76+/-34.3% (mean+/-s.e.m.) on day 5, after r-hCG infusion, suggesting that hCGbetacf is a metabolic product of the infused r-hCG...
  75. ncbi request reprint The androgen receptor CAG repeat polymorphism and X-chromosome inactivation in Australian Caucasian women with infertility related to polycystic ovary syndrome
    T Hickey
    Reproductive Medicine Unit, Department of Obstetrics and Gynecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
    J Clin Endocrinol Metab 87:161-5. 2002
    ..We conclude that the AR (CAG)n gene locus and/or its differential methylation patterns influence the disease process leading to PCOS...
  76. ncbi request reprint Factors and perceptions that influence women's decisions to have a single embryo transferred
    S de Lacey
    Discipline of Obstetrics and Gynaecology, Research Centre for Reproductive Health, School of Paediatrics and Reproductive Health, University of Adelaide, South Australia
    Reprod Biomed Online 15:526-31. 2007
    ..However, repeated treatment, advancing age and urgency to become pregnant are factors that moderate a woman's choice for SET...
  77. ncbi request reprint The effect of various infertility treatments on the risk of preterm birth
    J X Wang
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, 28 Woodville Rd, Woodville, South Australia 5011, Australia
    Hum Reprod 17:945-9. 2002
    ....
  78. pmc Genetic and gene expression analyses of the polycystic ovary syndrome candidate gene fibrillin-3 and other fibrillin family members in human ovaries
    Mark J Prodoehl
    Research Centre for Reproductive Health, Robinson Institute and School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, SA 5005, Australia
    Mol Hum Reprod 15:829-41. 2009
    ..2 are associated with PCOS or that FBN3 expression occurs in other organs and that this may be influencing the PCOS phenotype...
  79. doi request reprint Hyperandrogenemia, psychological distress, and food cravings in young women
    Siew S Lim
    Discipline of Physiology, School of Molecular and Biomedical Science, Adelaide University, SA 5000, Australia
    Physiol Behav 98:276-80. 2009
    ..Further investigations are required to elucidate the relationship between hyperandrogenemia and food cravings in young women...
  80. ncbi request reprint Troglitazone regulates peroxisome proliferator-activated receptors and inducible nitric oxide synthase in murine ovarian macrophages
    Cadence E Minge
    Research Centre for Reproductive Health, Department of Obstetrics and Gynaecology, University of Adelaide, Queen Elizabeth Hospital, Woodville, South Australia 5011, Australia
    Biol Reprod 74:153-60. 2006
    ..Additionally, ovarian macrophages respond directly to troglitazone to downregulate expression of proinflammatory Nos2, providing mechanistic information about ovarian effects of TZD treatment...
  81. ncbi request reprint Leptin and leptin receptor expression in the rat ovary
    Natalie K Ryan
    Reproductive Medicine Unit, Department of Obstetrics and Gynecology, University of Adelaide, Queen Elizabeth Hospital, Woodville, South Australia 5011, Australia
    Endocrinology 144:5006-13. 2003
    ....
  82. ncbi request reprint Improving reproductive performance in overweight/obese women with effective weight management
    Robert J Norman
    Reproductive Medicine Unit, University of Adelaide, The Queen Elizabeth Hospital, Woodville Rd, Woodville, SA5011, Australia
    Hum Reprod Update 10:267-80. 2004
    ....
  83. ncbi request reprint Effect of a synthetic progestin on the exercise status of sedentary young women
    Leanne M Redman
    Exercise Physiology Research Unit, Department of Obstetrics and Gynaecology, University of Adelaide, Australia
    J Clin Endocrinol Metab 90:3830-7. 2005
    ..The impact of progestins on exercise performance in women has not been previously studied...
  84. ncbi request reprint Glucose tolerance abnormalities in Australian women with polycystic ovary syndrome
    Preeti Dabadghao
    Research Centre for Reproductive Health, Discipline of Obstetrics and Gynaecology, University of Adelaide, Adelaide, SA, Australia
    Med J Aust 187:328-31. 2007
    ..To determine the prevalence of glucose tolerance abnormalities and to identify associated risk factors in women with polycystic ovary syndrome (PCOS) attending a reproductive endocrinology clinic...
  85. ncbi request reprint Genome instability is increased in lymphocytes of women with polycystic ovary syndrome and is correlated with insulin resistance
    Lisa J Moran
    Research Centre for Reproductive Health, Discipline of Obstetrics and Gynaecology, University of Adelaide, Adelaide, Australia
    Mutat Res 639:55-63. 2008
    ..The potential genetic contributors to PCOS are unclear. We tested the hypothesis that genomic instability (chromosome malsegregation and DNA damage) is increased in PCOS...
  86. ncbi request reprint Expression of leptin and its receptor in the murine ovary: possible role in the regulation of oocyte maturation
    Natalie K Ryan
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville Road, Woodville, South Australia 5011, Australia
    Biol Reprod 66:1548-54. 2002
    ..It is suggested that leptin may induce the production of another factor, possibly from thecal cells, that directly or indirectly acts on the oocyte to initiate germinal vesicle breakdown in this species...
  87. ncbi request reprint Characterization of ovarian function in granulocyte-macrophage colony-stimulating factor-deficient mice
    M J Jasper
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia 5011, Australia
    Biol Reprod 62:704-13. 2000
    ..Aberrant activation of these cells appears to compromise the luteinization process and the steroidogenic capacity of the corpus luteum during early pregnancy in GM-CSF-deficient mice...
  88. ncbi request reprint Preconception lifestyle advice for people with subfertility
    Kirsty Anderson
    The Robinson Institute, University of Adelaide, Adelaide, South Australia, Australia, 5005
    Cochrane Database Syst Rev 4:CD008189. 2010
    ..However, it does highlight the need for further research into this important subject...
  89. doi request reprint The effect of modifying dietary protein and carbohydrate in weight loss on arterial compliance and postprandial lipidemia in overweight women with polycystic ovary syndrome
    Lisa J Moran
    Discipline of Obstetrics and Gynaecology, Research Centre for Reproductive Health, School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, South Australia, Australia
    Fertil Steril 94:2451-4. 2010
    ..Modifying dietary carbohydrate or protein in weight loss provided similar improvements in arterial compliance and postprandial lipidemia...
  90. ncbi request reprint Infertility caused by HCG autoantibody
    Fred Amato
    Reproductive Medicine Unit, Department of Obstetrics and Gynecology, The University of Adelaide, The Queen Elizabeth Hospital, Adelaide, South Australia 5011, Australia
    J Clin Endocrinol Metab 87:993-7. 2002
    ..In addition, heat-inactivated serum and the affinity-purified IgG were shown to inhibit the action of hCG in an in vitro bioassay. We suggest that the persisting titer of the antibody to be responsible for the patient's infertility...
  91. ncbi request reprint Risk of multiple pregnancy when infertility is treated with ovulation induction by gonadotropins
    Jim X Wang
    Fertil Steril 80:664-5. 2003
  92. pmc Metformin in polycystic ovary syndrome: systematic review and meta-analysis
    Jonathan M Lord
    Department of Endocrinology and Metabolism, Peninsula Medical School, South West Centre for Reproductive Medicine, Derriford Hospital, Plymouth, Devon, PL6 8DH
    BMJ 327:951-3. 2003
    ..To assess the effectiveness of metformin in improving clinical and biochemical features of polycystic ovary syndrome...
  93. ncbi request reprint Overweight infertile patients have a higher fecundity than normal-weight women undergoing controlled ovarian hyperstimulation with intrauterine insemination
    Jim X Wang
    Fertil Steril 81:1710-2. 2004
    ..There is a positive effect of being overweight or obese on the pregnancy rate in women undergoing controlled ovarian hyperstimulation with intrauterine insemination...
  94. ncbi request reprint Surgically obtained sperm, and risk of gestational hypertension and pre-eclampsia
    Jim X Wang
    Lancet 359:673-4. 2002
    ....
  95. ncbi request reprint Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline
    Ricardo Azziz
    Cedars Sinai Medical Center and the David Geffen School of Medicine at the University of California, Los Angeles, California, USA
    J Clin Endocrinol Metab 91:4237-45. 2006
    ....
  96. ncbi request reprint Insulin resistance increases the risk of spontaneous abortion after assisted reproduction technology treatment
    Li Tian
    Reproductive Medical Centre, Peking University, People s Hospital, No 11 South Street, Xizhimen, Beijing, China 100044
    J Clin Endocrinol Metab 92:1430-3. 2007
    ..This study aims to examine the impact of insulin resistance (IR) on the risk of spontaneous abortion in patients who received infertility treatment...
  97. ncbi request reprint The effect of a hypocaloric diet with and without exercise training on body composition, cardiometabolic risk profile, and reproductive function in overweight and obese women with polycystic ovary syndrome
    Rebecca L Thomson
    Australian Technology Network Centre for Metabolic Fitness and Nutritional Physiology Research Centre, Sansom Institute for Health Research, University of South Australia, Adelaide, Australia
    J Clin Endocrinol Metab 93:3373-80. 2008
    ..In overweight women with polycystic ovary syndrome (PCOS), the benefits of the addition of exercise to an energy-restricted diet in further improving cardiometabolic risk factors and reproductive function has not been extensively studied...
  98. doi request reprint Dietary therapy in polycystic ovary syndrome
    Lisa J Moran
    The Jean Hailes Foundation for Women s Health, Monash Institute for Public Health Research, Monash Medical Centre, Clayton, Victoria, Australia
    Semin Reprod Med 26:85-92. 2008
    ..Future research should focus on the optimal dietary strategies and exercise regimens for PCOS treatment and the relative efficacy and appropriate use of lifestyle management versus antiobesity pharmacologic agents and surgery...
  99. ncbi request reprint Polycystic ovarian syndrome: marked differences between endocrinologists and gynaecologists in diagnosis and management
    Andrea J Cussons
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Clin Endocrinol (Oxf) 62:289-95. 2005
    ..Women with polycystic ovarian syndrome (PCOS) commonly consult endocrinologists or gynaecologists and it is not known whether these specialty groups differ in their approach to management...
  100. ncbi request reprint A randomized controlled trial of a soft double lumen embryo transfer catheter versus a firm single lumen catheter: significant improvements in pregnancy rates
    Janelle A McDonald
    Suite 14, John James Medical Centre, 175 Strickland Crescent, Deakin, ACT 2600, Australia
    Hum Reprod 17:1502-6. 2002
    ..We compared the clinical pregnancy rates with the single lumen catheter (TCC) and the double lumen catheter (CC) in a randomized single blind trial...
  101. ncbi request reprint Safety and efficacy of a testosterone metered-dose transdermal spray for treating decreased sexual satisfaction in premenopausal women: a randomized trial
    Susan Davis
    Women s Health Program, Department of Medicine, Monash University, Alfred Hospital, Prahran, Victoria, Australia
    Ann Intern Med 148:569-77. 2008
    ..It is not known whether premenopausal women who report low sexual satisfaction and have low circulating testosterone levels will benefit from testosterone therapy...