P E Norman

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi request reprint Infrarenal aortic diameter predicts all-cause mortality
    Paul Norman
    School of Surgery and Pathology, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia
    Arterioscler Thromb Vasc Biol 24:1278-82. 2004
  2. ncbi request reprint Long-term relative survival following surgery for abdominal aortic aneurysm: a review
    P E Norman
    University Department of Surgery, Fremantle Hospital, PO Box 480, Western Australia, 6959 Fremantle, Australia
    Cardiovasc Surg 9:219-24. 2001
  3. ncbi request reprint Maternal and postnatal vitamin D ingestion influences rat aortic structure, function and elastin content
    Paul Norman
    University Department of Surgery, Fremantle Hospital, P O Box 480, Western Australia 6959, Fremantle, Australia
    Cardiovasc Res 55:369-74. 2002
  4. ncbi request reprint Peripheral arterial disease: prognostic significance and prevention of atherothrombotic complications
    Paul E Norman
    School of Surgery and Pathology, Fremantle Hospital, PO Box 480, Fremantle, WA 6959, Australia
    Med J Aust 181:150-4. 2004
  5. ncbi request reprint Long-term relative survival in elderly patients after carotid endarterectomy: a population-based study
    Paul E Norman
    School of Surgery and Pathology, University of Western Australia, Fremantle Hospital, PO Box 480, Fremantle, Western Australia 6959
    Stroke 34:e95-8. 2003
  6. ncbi request reprint C-reactive protein levels and the expansion of screen-detected abdominal aortic aneurysms in men
    Paul Norman
    School of Surgery and Pathology, The University of Western Australia, Fremantle Hospital, Fremantle, Western Australia
    Circulation 110:862-6. 2004
  7. pmc Population based randomised controlled trial on impact of screening on mortality from abdominal aortic aneurysm
    Paul E Norman
    School of Surgery and Pathology, University of Western Australia, Fremantle Hospital, PO Box 480, Fremantle, WA 6959, Australia
    BMJ 329:1259. 2004
  8. ncbi request reprint The influence of gender on outcome following peripheral vascular surgery: a review
    P E Norman
    University Department of Surgery, Fremantle Hospital, Western Australia, Australia
    Cardiovasc Surg 8:111-5. 2000
  9. pmc Long term relative survival after surgery for abdominal aortic aneurysm in western Australia: population based study
    P E Norman
    University Department of Surgery, Fremantle Hospital, PO Box 480, Fremantle, Western Australia 6959, Australia
    BMJ 317:852-6. 1998
  10. ncbi request reprint Peripheral arterial disease and risk of cardiac death in type 2 diabetes: the Fremantle Diabetes Study
    Paul E Norman
    School of Surgery and Pathology, Fremantle Hospital, P O Box 480, Fremantle, Western Australia 6959, Australia
    Diabetes Care 29:575-80. 2006

Detail Information

Publications58

  1. ncbi request reprint Infrarenal aortic diameter predicts all-cause mortality
    Paul Norman
    School of Surgery and Pathology, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia
    Arterioscler Thromb Vasc Biol 24:1278-82. 2004
    ..To assess the relationship between infrarenal aortic diameter and subsequent all-cause mortality in men aged 65 years or older...
  2. ncbi request reprint Long-term relative survival following surgery for abdominal aortic aneurysm: a review
    P E Norman
    University Department of Surgery, Fremantle Hospital, PO Box 480, Western Australia, 6959 Fremantle, Australia
    Cardiovasc Surg 9:219-24. 2001
    ..This is in marked contrast to the situation for patients with malignant disease. With the current interest in population screening and endoluminal stenting for AAA, an understanding of long-term survival is increasingly important...
  3. ncbi request reprint Maternal and postnatal vitamin D ingestion influences rat aortic structure, function and elastin content
    Paul Norman
    University Department of Surgery, Fremantle Hospital, P O Box 480, Western Australia 6959, Fremantle, Australia
    Cardiovasc Res 55:369-74. 2002
    ..Here we have investigated, in rats, the hypothesis that increased exposure to vitamin D during gestation and in the postnatal period alters aortic elastin content and aortic function...
  4. ncbi request reprint Peripheral arterial disease: prognostic significance and prevention of atherothrombotic complications
    Paul E Norman
    School of Surgery and Pathology, Fremantle Hospital, PO Box 480, Fremantle, WA 6959, Australia
    Med J Aust 181:150-4. 2004
    ..Patients with PAD require medical management to prevent future coronary and cerebral vascular events. There are currently insufficient data to recommend routine population screening for asymptomatic PAD using the ABPI...
  5. ncbi request reprint Long-term relative survival in elderly patients after carotid endarterectomy: a population-based study
    Paul E Norman
    School of Surgery and Pathology, University of Western Australia, Fremantle Hospital, PO Box 480, Fremantle, Western Australia 6959
    Stroke 34:e95-8. 2003
    ..The aim of the present study was to assess relative survival in those patients >or=80 years of age undergoing carotid endarterectomy...
  6. ncbi request reprint C-reactive protein levels and the expansion of screen-detected abdominal aortic aneurysms in men
    Paul Norman
    School of Surgery and Pathology, The University of Western Australia, Fremantle Hospital, Fremantle, Western Australia
    Circulation 110:862-6. 2004
    ..CRP levels have also been found to be elevated in patients with abdominal aortic aneurysms (AAAs). The aim of this study was to assess the relation between CRP levels and rates of expansion of small AAAs...
  7. pmc Population based randomised controlled trial on impact of screening on mortality from abdominal aortic aneurysm
    Paul E Norman
    School of Surgery and Pathology, University of Western Australia, Fremantle Hospital, PO Box 480, Fremantle, WA 6959, Australia
    BMJ 329:1259. 2004
    ..To assess whether screening for abdominal aortic aneurysms in men reduces mortality...
  8. ncbi request reprint The influence of gender on outcome following peripheral vascular surgery: a review
    P E Norman
    University Department of Surgery, Fremantle Hospital, Western Australia, Australia
    Cardiovasc Surg 8:111-5. 2000
    ..The causes may include delayed diagnosis and referral, increased co-morbidity and possibly the effect of smaller arteries in women...
  9. pmc Long term relative survival after surgery for abdominal aortic aneurysm in western Australia: population based study
    P E Norman
    University Department of Surgery, Fremantle Hospital, PO Box 480, Fremantle, Western Australia 6959, Australia
    BMJ 317:852-6. 1998
    ..To determine the long term relative survival of all patients who had surgery for abdominal aortic aneurysm in Western Australia during 1985-94...
  10. ncbi request reprint Peripheral arterial disease and risk of cardiac death in type 2 diabetes: the Fremantle Diabetes Study
    Paul E Norman
    School of Surgery and Pathology, Fremantle Hospital, P O Box 480, Fremantle, Western Australia 6959, Australia
    Diabetes Care 29:575-80. 2006
    ..The purpose of this study was to examine the natural history of peripheral arterial disease (PAD) complicating type 2 diabetes, in particular the influence of PAD on the risk of cardiac death and the adequacy of PAD risk factor management...
  11. doi request reprint Matrix metalloproteinase-2 gene variants and abdominal aortic aneurysm
    L Smallwood
    School of Surgery, University of Western Australia, Fremantle Hospital, Fremantle, WA 6959, Australia
    Eur J Vasc Endovasc Surg 38:169-71. 2009
    ..To investigate associations between two polymorphisms of the matrix metalloproteinase-2 gene (MMP2) and the incidence and progression of abdominal aortic aneurysm (AAA)...
  12. ncbi request reprint The Quality of Surgical Care Project: benchmark standards of open resection for abdominal aortic aneurysm in Western Australia
    J B Semmens
    Centre for Health Services Research, Department of Public Health, University of Western Australia, Nedlands, Australia
    Aust N Z J Surg 68:404-10. 1998
    ..The purpose of this study is to establish benchmark standards in WA for operative mortality, 5-year survival and length of stay in all patients who were surgically treated for aneurysm of the abdominal aorta (AAA) in WA...
  13. ncbi request reprint Falling incidence of amputations for peripheral occlusive arterial disease in Western Australia between 1980 and 1992
    E Mattes
    Department of Surgery, University of Western Australia, Australia
    Eur J Vasc Endovasc Surg 13:14-22. 1997
    ..To assess temporal trends in the incidence of surgical procedures for peripheral occlusive arterial disease (POAD) and associated changes in outcome as measured by the rate of major lower limb amputations for POAD...
  14. pmc Polymorphisms of the matrix metalloproteinase 9 gene and abdominal aortic aneurysm
    L Smallwood
    Schools of Surgery, University of Western Australia, Fremantle, Western Australia
    Br J Surg 95:1239-44. 2008
    ..Increased matrix metalloproteinase (MMP) 9 activity has been implicated in the formation of abdominal aortic aneurysm (AAA). The aim was to explore the association between potentially functional variants of the MMP-9 gene and AAA...
  15. ncbi request reprint Does the Mediterranean paradox extend to abdominal aortic aneurysm?
    K Jamrozik
    Department of Public Health, The University of Western Australia, Nedlands, Western Australia
    Int J Epidemiol 30:1071-5. 2001
    ..We sought to test, in men undergoing ultrasound screening for abdominal aortic aneurysms (AAA) in Western Australia, clinical impressions that the prevalence of AAA is high in Dutch migrants and low in migrants from Mediterranean countries...
  16. ncbi request reprint Abdominal aortic aneurysm: the prognosis in women is worse than in men
    P E Norman
    School of Surgery and Pathology, University of Western Australia, Fremantle, Western Australia
    Circulation 115:2865-9. 2007
  17. ncbi request reprint Population-based study of carotid endarterectomy in Western Australia
    C L Laurvick
    Centre for Health Services Research, School of Population Health, Western Australia, Australia
    Br J Surg 91:168-73. 2004
    ..The aim of this study was to determine whether carotid endarterectomy rates have continued to rise despite the reducing trend in most manifestations of atherosclerotic cardiovascular disease...
  18. doi request reprint Associations of total osteocalcin with all-cause and cardiovascular mortality in older men. The Health In Men Study
    B B Yeap
    School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia
    Osteoporos Int 23:599-606. 2012
    ..Differences in osteocalcin levels might influence glucose metabolism and thereby cardiovascular risk, or reflect changes in bone turnover thus representing a marker for poorer health outcomes...
  19. ncbi request reprint Negative association between infra-renal aortic diameter and glycaemia: the Health in Men Study
    M T Q Le
    School of Surgery and Pathology, The University of Western Australia, Nedlands, Western Australia, Australia
    Eur J Vasc Endovasc Surg 33:599-604. 2007
    ..The aim of this study was to assess whether there is a similar relationship between both diabetes and glucose level, and infra-renal aortic diameter throughout its range...
  20. ncbi request reprint Prevalence of abdominal aortic aneurysms in men with diabetes
    E Mattes
    Department of Surgery, University of Western Australia, Fremantle Hospital, WA
    Med J Aust 166:630-3. 1997
    ..To assess the prevalence of abdominal aortic aneurysm (AAA) in men with diabetes aged 60 years and over...
  21. ncbi request reprint Screening for abdominal aortic aneurysm: lessons from a population-based study
    K Jamrozik
    Department of Public Health, University of Western Australia, Nedlands
    Med J Aust 173:345-50. 2000
    ..To test the acceptability of screening and to identify modifiable risk factors for abdominal aortic aneurysm (AAA) in men...
  22. ncbi request reprint The potential for a selective screening strategy for abdominal aortic aneurysm
    C A Spencer
    Department of Public Health, University of Western Australia, Nedlands
    J Med Screen 7:209-11. 2000
    ..To investigate the feasibility of selective screening for abdominal aortic aneurysm (AAA) based on identification of a target group of manageable size defined by risk factors for AAA...
  23. ncbi request reprint Successful mental health aging: results from a longitudinal study of older Australian men
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Royal Perth Hospital, Perth, WA 6009, Australia
    Am J Geriatr Psychiatry 14:27-35. 2006
    ..The authors investigated the associations of medical and lifestyle factors with the mental health of men in their 80s...
  24. ncbi request reprint B-vitamins reduce plasma levels of beta amyloid
    Leon Flicker
    School of Medicine and Pharmacology, University of Western Australia, Australia
    Neurobiol Aging 29:303-5. 2008
    ..E.) increase of A beta 40 was 7.0 pg/ml (8.4) in the vitamin group (4.9%), and 26.8 pg/ml (7.7) (18.5%) in the placebo group. We conclude that B vitamins may decrease the plasma level of A beta 40 and have a role in the prevention of AD...
  25. doi request reprint Homocysteine and depression in later life
    Osvaldo P Almeida
    FRANZCP, Western Australian Centre for Health and Ageing, University of Western Australia, Mail Box M573, 35 Stirling Hwy, Crawley, WA 6009, Australia
    Arch Gen Psychiatry 65:1286-94. 2008
    ..Genetic association studies are not prone to the same sources of error and offer an opportunity to explore the consistency and external validity of this association...
  26. ncbi request reprint Association of cardiovascular risk factors and disease with depression in later life
    Osvaldo P Almeida
    Unit of Geriatric Psychiatry, University of Western Australia and Royal Perth Hospital, Perth, WA, Australia
    Am J Geriatr Psychiatry 15:506-13. 2007
    ..The objective of this study is to determine the association between established cardiovascular risk factors and depression among older men...
  27. ncbi request reprint The association between C-reactive protein concentration and depression in later life is due to poor physical health: results from the Health in Men Study (HIMS)
    Osvaldo P Almeida
    WA Centre for Health and Ageing, University of Western Australia, Australia
    Psychol Med 37:1775-86. 2007
    ..This study aimed to investigate the association between high CRP concentration and depression while taking physical health into account...
  28. ncbi request reprint Efficacy of B vitamins in lowering homocysteine in older men: maximal effects for those with B12 deficiency and hyperhomocysteinemia
    Leon Flicker
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Stroke 37:547-9. 2006
    ..Previous studies, largely in younger individuals, have shown that B vitamins lowered tHcy by substantial amounts and that this effect is greater in people with higher tHcy and lower folate levels...
  29. ncbi request reprint Improving maximum walking distance in early peripheral arterial disease: randomised controlled trial
    Bess Fowler
    University of Western Australia, Australia
    Aust J Physiother 48:269-75. 2002
    ..A combination of simple and safe interventions that are readily available in the community through physiotherapists and general practitioners has the potential to improve early peripheral arterial disease...
  30. ncbi request reprint Is there an association between chronic lung disease and abdominal aortic aneurysm expansion?
    Carole Spencer
    School of Population Health, The University of Western Australia, Nedlands, Western Australia, Australia
    ANZ J Surg 73:787-9. 2003
    ..We sought such an association in a cohort of men with aneurysms detected in a population-based study of screening for aneurysms...
  31. ncbi request reprint Predictors, consequences and costs of diabetes-related lower extremity amputation complicating type 2 diabetes: the Fremantle Diabetes Study
    W A Davis
    School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, PO Box 480, Fremantle, WA 6959, Australia
    Diabetologia 49:2634-41. 2006
    ..The aims of this study were to assess the incidence, predictors, consequences, and inpatient cost of lower extremity amputation (LEA) in a community-based cohort of type 2 diabetic patients...
  32. doi request reprint Peripheral arterial disease increases the risk of subsequent hip fracture in older men: the Health in Men Study
    Z Hyde
    Western Australian Centre for Health and Ageing, Centre for Medical Research, Western Australian Institute for Medical Research, University of Western Australia, Perth, WA, Australia
    Osteoporos Int 24:1683-8. 2013
    ..There was no association between claudication and hip fracture, but there was a significant association with an ankle brachial index (ABI) <0.9...
  33. ncbi request reprint Polymorphisms of the interleukin-6 gene promoter and abdominal aortic aneurysm
    L Smallwood
    School of Surgery and Pathology, University of Western Australia
    Eur J Vasc Endovasc Surg 35:31-6. 2008
    ..Genetic association studies are one means of trying to clarify the role of specific mediators in the causal pathway. The aim of the present study was to examine the association between variants of the IL-6 gene and AAAs...
  34. ncbi request reprint Vitamin D, shedding light on the development of disease in peripheral arteries
    P E Norman
    School of Surgery and Pathology, The University of Western Australia, Fremantle Hospital, Fremantle, Western Australia
    Arterioscler Thromb Vasc Biol 25:39-46. 2005
    ..This review explores the relationship between vitamin D and a range of physiological and pathological processes relevant to peripheral arteries...
  35. ncbi request reprint The anatomical distribution of iliac aneurysms: is there an embryological basis?
    P E Norman
    University Department of Surgery, Fremantle Hospital, Fremantle, Western Australia
    Eur J Vasc Endovasc Surg 25:82-4. 2003
  36. ncbi request reprint Development of a rapid genotyping method for single nucleotide polymorphisms and its application in cancer studies
    Fabienne Grieu
    Department of Radiation Oncology, Sir Charles Gairdner Hospital, University of Western Australia, Nedlands 6009, Australia
    Oncol Rep 11:501-4. 2004
    ..The low start-up and running costs make this method particularly well suited for SNP genotyping studies that involve up to 1,000 DNA samples...
  37. ncbi request reprint Carotid endarterectomy in octogenarians
    Raphael Varghese
    School of Surgery and Pathology, The University of Western Australia, Fremantle Hospital, Fremantle, Western Australia
    ANZ J Surg 74:215-7. 2004
    ..The aim of the present study was to determine the trends and early outcome of carotid endarterectomy performed in octogenarians at a single institution...
  38. doi request reprint Lower sex hormone-binding globulin is more strongly associated with metabolic syndrome than lower total testosterone in older men: the Health in Men Study
    S A Paul Chubb
    PathWest, Department of Biochemistry, Fremantle Hospital, Western Australia, 6160 Australia
    Eur J Endocrinol 158:785-92. 2008
    ..As SHBG increases with age while testosterone declines, we examined the relative contributions of SHBG and testosterone to the risk of metabolic syndrome in older men...
  39. doi request reprint Diabetes and aortic aneurysm
    Jonathan Golledge
    Am J Cardiol 101:1680-1. 2008
  40. pmc Management of peripheral arterial disease in the elderly: focus on cilostazol
    Travis M Falconer
    School of Surgery, University of Western Australia, Fremantle Hospital, Western Australia, Australia
    Clin Interv Aging 3:17-23. 2008
    ..In addition to risk factor management, treatment with cilostazol should be considered in patients with disabling IC...
  41. ncbi request reprint Lifestyle still predicts mortality in older men with established vascular disease
    Carole A Spencer
    School of Population Health, The University of Western Australia, Nedlands, Australia
    Prev Med 41:583-8. 2005
    ..No previous studies have examined the patterns of lifestyle in elderly men with and without clinically evident vascular disease by using a lifestyle score to predict survival...
  42. ncbi request reprint Is screening for abdominal aortic aneurysm bad for your health and well-being?
    Carole A Spencer
    School of Population Health, University of Western Australia, Nedlands, WA, Australia
    ANZ J Surg 74:1069-75. 2004
    ..The purpose of the present paper was to investigate whether screening for abdominal aortic aneurysm (AAA) causes health-related quality of life to change in men or their partners...
  43. ncbi request reprint Medical treatment of peripheral arterial disease
    Graeme J Hankey
    Department of Neurology, Royal Perth Hospital and School of Medicine and Pharmacology, University of Western Australia, Perth
    JAMA 295:547-53. 2006
    ..The goals of treatment are to prevent future major coronary and cerebrovascular events and improve leg symptoms...
  44. ncbi request reprint In men older than 70 years, total testosterone remains stable while free testosterone declines with age. The Health in Men Study
    Bu B Yeap
    School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia
    Eur J Endocrinol 156:585-94. 2007
    ..We sought to determine the distribution and associations of reduced testosterone concentrations in older men...
  45. ncbi request reprint Homocysteine and vitamin status in older people in Perth
    Leon A Flicker
    Med J Aust 180:539-40. 2004
  46. ncbi request reprint A simple lifestyle score predicts survival in healthy elderly men
    Carole A Spencer
    School of Population Health, University of Western Australia, Clifton St, Nedlands, Western Australia 6907, Australia
    Prev Med 40:712-7. 2005
    ....
  47. ncbi request reprint Association between osteopontin and human abdominal aortic aneurysm
    Jonathan Golledge
    The Vascular Biology Unit, School of Medicine, James Cook University, Townsville, Queensland, 4811 Australia
    Arterioscler Thromb Vasc Biol 27:655-60. 2007
    ..The relationship between serum concentration of OPN and variants of the OPN gene with human abdominal aortic aneurysm (AAA) was investigated...
  48. doi request reprint Abdominal aortic aneurysm events in postmenopausal women
    Janet T Powell
    BMJ 337:a1894. 2008
  49. ncbi request reprint Matrix biology of abdominal aortic aneurysms in diabetes: mechanisms underlying the negative association
    Paul E Norman
    School of Surgery and Pathology, University of Western Australia, Fremantle, Western Australia
    Connect Tissue Res 48:125-31. 2007
    ..The aim of our present minireview is to compare the changes in matrix biology seen in diabetes and AAA and to explore molecular mechanisms that may explain the negative association and identify possible therapeutic implications...
  50. ncbi request reprint Abdominal aortic aneurysm repair in octogenarians
    Paul E Norman
    ANZ J Surg 72:612. 2002
  51. ncbi request reprint Comparative roles of microvascular and nerve function in foot ulceration in type 2 diabetes: response to Krishnan et al
    Dean T Williams
    Diabetes Care 27:3026; author reply 3026-7. 2004
  52. ncbi request reprint Indications for operative management of abdominal aortic aneurysms
    Faraz Shakibaie
    School of Surgery and Pathology, The University of Western Australia, Perth, Western Australia, Australia
    ANZ J Surg 74:470-6. 2004
    ..This review makes recommendations on the management of small abdominal aortic aneurysms according to the current available evidence...
  53. doi request reprint Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte-matrix interactions
    Jonathan Golledge
    Vascular Biology Unit, Department of Surgery, School of Medicine, James Cook University, Townsville, Qld 4811, Australia
    Eur Heart J 29:665-72. 2008
    ..The reason for this difference is unknown. We examined the role of diabetes and glycation on AAA expansion and extracellular matrix-monocyte interactions...
  54. pmc Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohorts
    Gregory T Jones
    Department of Surgery, University of Otago, New Zealand
    Arterioscler Thromb Vasc Biol 28:764-70. 2008
    ..This study was undertaken, using the largest case series yet reported, to determine whether common genetic variants of the RAS are associated with either susceptibility or severity of AAA...
  55. ncbi request reprint Relationship between two sequence variations in the gene for peroxisome proliferator-activated receptor-gamma and plasma homocysteine concentration. Health in men study
    Jonathan Golledge
    The Vascular Biology Unit, Department of Surgery, School of Medicine, James Cook University, Townsville, QLD, 4811, Australia
    Hum Genet 123:35-40. 2008
    ..005). Our findings demonstrate a new genotypic association with plasma homocysteine. Replication will be required in other cohorts...
  56. ncbi request reprint Homocysteine and abdominal aortic aneurysms
    Paul Moroz
    School of Surgery and Pathology, University of Western Australia, Fremantle Hospital, Perth, Western Australia, Australia
    ANZ J Surg 77:329-32. 2007
    ..Further research is needed, given the potential benefit that simple vitamin supplementation may have for patients with AAA...
  57. ncbi request reprint Obesity, adipokines, and abdominal aortic aneurysm: Health in Men study
    Jonathan Golledge
    Vascular Biology Unit, Department of Surgery, School of Medicine, James Cook University, Townsville, QLD, Australia 4811
    Circulation 116:2275-9. 2007
    ..Obesity is associated with occlusive artery disease but is not considered a risk factor for abdominal aortic aneurysm (AAA). We investigated the association between anthropometric measures of obesity, serum adipokines, and AAA...