S K Nilsson

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. ncbi request reprint Hyaluronan is synthesized by primitive hemopoietic cells, participates in their lodgment at the endosteum following transplantation, and is involved in the regulation of their proliferation and differentiation in vitro
    Susan K Nilsson
    Stem Cell Biology Laboratory, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Blood 101:856-62. 2003
  2. ncbi request reprint Hemopoietic stem cells with higher hemopoietic potential reside at the bone marrow endosteum
    David N Haylock
    Australian Stem Cell Centre, Victoria, Australia
    Stem Cells 25:1062-9. 2007
  3. pmc Cells capable of bone production engraft from whole bone marrow transplants in nonablated mice
    S K Nilsson
    Cancer Center and the Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01605, USA
    J Exp Med 189:729-34. 1999
  4. ncbi request reprint Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches
    S K Nilsson
    Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Blood 97:2293-9. 2001
  5. ncbi request reprint Transplantable stem cells: home to specific niches
    Susan K Nilsson
    Stem Cell Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia
    Curr Opin Hematol 11:102-6. 2004
  6. ncbi request reprint Recent Australian experience with hemopoietic stem and progenitor cell expansion
    S K Nilsson
    Australian Stem Cell Center, Clayton, Melbourne, Australia
    Cytotherapy 9:231-5. 2007
  7. ncbi request reprint Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor
    J P Levesque
    Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia
    Blood 98:1289-97. 2001
  8. ncbi request reprint Granulocyte-macrophage colony-stimulating factor is not responsible for the correction of hematopoietic deficiencies in the maturing op/op mouse
    S K Nilsson
    Sir Donald and Lady Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Melbourne, Australia
    Blood 86:66-72. 1995
  9. ncbi request reprint Age-related changes in extramedullary hematopoiesis in the spleen of normal and perturbed osteopetrotic (op/op) mice
    S K Nilsson
    Cell Biology Group, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Exp Hematol 22:377-83. 1994
  10. ncbi request reprint Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow
    Jean Pierre Levesque
    Mater Medical Research Institute, Raymond Terrace, Aubigny Place, South Brisbane, QLD, Australia
    Stem Cells 25:1954-65. 2007

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Hyaluronan is synthesized by primitive hemopoietic cells, participates in their lodgment at the endosteum following transplantation, and is involved in the regulation of their proliferation and differentiation in vitro
    Susan K Nilsson
    Stem Cell Biology Laboratory, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Blood 101:856-62. 2003
    ..Collectively, these data describe an important yet previously unrecognized role for HA in the biology of primitive hemopoietic progenitor cells...
  2. ncbi request reprint Hemopoietic stem cells with higher hemopoietic potential reside at the bone marrow endosteum
    David N Haylock
    Australian Stem Cell Centre, Victoria, Australia
    Stem Cells 25:1062-9. 2007
    ....
  3. pmc Cells capable of bone production engraft from whole bone marrow transplants in nonablated mice
    S K Nilsson
    Cancer Center and the Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01605, USA
    J Exp Med 189:729-34. 1999
    ..Transplanted cells were also detected as flattened bone lining cells on the periosteal bone surface...
  4. ncbi request reprint Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches
    S K Nilsson
    Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Blood 97:2293-9. 2001
    ..Together, these data strongly support historical evidence of the presence of endosteal hemopoietic stem cell niches...
  5. ncbi request reprint Transplantable stem cells: home to specific niches
    Susan K Nilsson
    Stem Cell Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia
    Curr Opin Hematol 11:102-6. 2004
    ....
  6. ncbi request reprint Recent Australian experience with hemopoietic stem and progenitor cell expansion
    S K Nilsson
    Australian Stem Cell Center, Clayton, Melbourne, Australia
    Cytotherapy 9:231-5. 2007
    ..The first was an attempt to deliver a gene therapy for treatment of HIV and the second an attempt to improve rates of hemopoietic recovery with ex vivo generated myeloid cells...
  7. ncbi request reprint Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor
    J P Levesque
    Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia
    Blood 98:1289-97. 2001
    ....
  8. ncbi request reprint Granulocyte-macrophage colony-stimulating factor is not responsible for the correction of hematopoietic deficiencies in the maturing op/op mouse
    S K Nilsson
    Sir Donald and Lady Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Melbourne, Australia
    Blood 86:66-72. 1995
    ..This finding suggests that an alternate regulatory factor can be involved in macrophage and osteoclast commitment, differentiation, and function in vivo...
  9. ncbi request reprint Age-related changes in extramedullary hematopoiesis in the spleen of normal and perturbed osteopetrotic (op/op) mice
    S K Nilsson
    Cell Biology Group, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Exp Hematol 22:377-83. 1994
    ..The response of these mice to a 5-fluorouracil (5-FU) cytotoxic challenge suggested that this pool of primitive progenitor cells acted as a hematopoietic reserve capable of rapidly responding to hematopoietic perturbation...
  10. ncbi request reprint Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow
    Jean Pierre Levesque
    Mater Medical Research Institute, Raymond Terrace, Aubigny Place, South Brisbane, QLD, Australia
    Stem Cells 25:1954-65. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  11. ncbi request reprint Hemopoietic stem cell engraftment
    Susan K Nilsson
    Stem Cell Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
    Exp Hematol 34:123-9. 2006
  12. ncbi request reprint Stem cell regulation by the hematopoietic stem cell niche
    David N Haylock
    Stem Cell Research Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia
    Cell Cycle 4:1353-5. 2005
    ....
  13. ncbi request reprint Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells
    Susan K Nilsson
    Stem Cell Laboratory, Peter MacCallum Cancer Centre, Locked Bag 1, A Beckett St, Melbourne, Victoria, Australia, 3000
    Blood 106:1232-9. 2005
    ..These data therefore provide strong evidence that Opn is an important component of the HSC niche which participates in HSC location and as a physiologic-negative regulator of HSC proliferation...
  14. ncbi request reprint Membrane-bound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region
    Rebecca L Driessen
    Stem Cell Laboratories, Peter MacCallum Cancer Centre, A Beckett Street, Melbourne, Victoria 3000, Australia
    Exp Hematol 31:1284-91. 2003
    ..In addition, in vivo SCF has been shown to play a role in cell mobilization and migration. The aim of this study was to determine if SCF is an integral component of the hemopoietic "niche" of the bone marrow in situ...
  15. ncbi request reprint The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer
    Lishanthi Udabage
    Laboratory for Hyaluronan Research, Department of Biochemistry and Molecular Biology, Monash University, Wellington Road, Clayton, Victoria 3800, Australia
    Exp Cell Res 310:205-17. 2005
    ..There was a correlation between elevated levels of HA synthesis, CD44 expression and cancer cell migration thereby highlighting the pivotal role that HA metabolism plays in the aggressive breast cancer phenotype...
  16. ncbi request reprint Gene expression, synthesis and degradation of hyaluronan during differentiation of 3T3-L1 adipocytes
    Peter G Allingham
    Cooperative Research Centre for Cattle and Beef Quality, CSIRO Livestock Industries, Queensland Bioscience Precinct, 306 Carmody Road, St Lucia, QLD 4067, Australia
    Arch Biochem Biophys 452:83-91. 2006
    ....
  17. ncbi request reprint Osteopontin: a bridge between bone and blood
    David N Haylock
    Niche Laboratory, Australian Stem Cell Centre, Monash University, Clayton, Vic, Australia
    Br J Haematol 134:467-74. 2006
    ..Through osteoblasts and their cell surface and expressed proteins including Opn, bone is able to regulate the tissue that resides within it. In doing so, Opn can be considered a bridge between bone and blood...
  18. ncbi request reprint Antisense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer
    Lishanthi Udabage
    Laboratory for Hyaluronan Research, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
    Cancer Res 65:6139-50. 2005
    ..Collectively, these unique results strongly implicate the central role of HAS2 in the initiation and progression of breast cancer, potentially highlighting the co-dependency between HAS2, CD44, and HYAL2 expression...
  19. ncbi request reprint The role of hyaluronic acid in hemopoietic stem cell biology
    David N Haylock
    Australian Stem Cell Centre, PO Box 8002, Monash University LPO, Victoria 3168, Australia
    Regen Med 1:437-45. 2006
    ....
  20. ncbi request reprint Expansion of umbilical cord blood for clinical transplantation
    David N Haylock
    Australian Stem Cell Centre, P O Box 8002, Monash University LPO, Victoria 3168, Australia
    Curr Stem Cell Res Ther 2:324-35. 2007
    ....