Research Topics
| J NiklesSummaryAffiliation: University of Queensland Country: Australia Publications
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Detail Information
Publications
An n-of-1 trial service in clinical practice: testing the effectiveness of stimulants for attention-deficit/hyperactivity disorderC Jane Nikles
The University of Queensland, Herston, Queensland 4006, Australia
Pediatrics 117:2040-6. 2006..We sought to describe the clinical use of n-of-1 trials for attention-deficit/hyperactivity disorder in publicly and privately funded family and specialized pediatric practice in Australia...
Long-term changes in management following n-of-1 trials of stimulants in attention-deficit/hyperactivity disorderC Jane Nikles
School of Medicine, University of Queensland, Queensland, Australia
Eur J Clin Pharmacol 63:985-9. 2007..Our objective was to evaluate the long-term impact of n-of-1 trials-within-patient randomised, double-blind, cross-over comparisons of stimulant versus placebo or stimulant-on ADHD management...
Prioritising drugs for single patient (n-of-1) trials in palliative careJ Nikles
Discipline of General Practice, The University of Queensland, Herston, Brisbane, Queensland, Australia
Palliat Med 23:623-34. 2009..Although not all the drugs used in palliative care are suitable, SPTs provide a potential alternative method of gathering evidence in palliative care...
Mothers' mental illness and child behavior problems: cause-effect association or observation bias?J M Najman
Department of Anthropology and Sociology, University of Queensland, Australia
J Am Acad Child Adolesc Psychiatry 39:592-602. 2000..However, the validity of this finding is in doubt because the majority of these studies have relied on maternal reports as indicators of children's behavior...
Bias influencing maternal reports of child behaviour and emotional stateJ M Najman
School of Social Science, The University of Queensland, Australia
Soc Psychiatry Psychiatr Epidemiol 36:186-94. 2001..We examine two potential sources of bias that may influence reports of a child's behaviour/mental health. The first is the mental or emotional impairment of the respondent; the second concerns gender-related expectations of children...
The role of paracetamol in chronic pain: an evidence-based approachC Jane Nikles
Discipline of General Practice, The University of Queensland, Herston, Herston, Queensland 4006, Australia
Am J Ther 12:80-91. 2005..In patients with chronic pain, paracetamol can play an important role as an NSAID sparer, with resultant benefits in terms of reduced adverse effects and cost savings...
Do individualized medication effectiveness tests (n-of-1 trials) change clinical decisions about which drugs to use for osteoarthritis and chronic pain?C Jane Nikles
Discipline of General Practice, The University of Queensland, Herston, Queensland, Australia
Am J Ther 12:92-7. 2005..Our results provide a new (individual) perspective on the well-known recommendation for paracetamol as first-line treatment for chronic pain and demonstrate that it is feasible to provide IMETs nationally by mail and telephone...
Using n-of-1 trials as a clinical tool to improve prescribingC Jane Nikles
Discipline of General Practice, University of Queensland Medical School, Herston, Queensland 4006, Australia
Br J Gen Pract 55:175-80. 2005..We have investigated the use of these, offered to doctors as individualised medication effectiveness tests (IMETs), as a tool to improve drug prescribing...
