Research Topics
| K W NgSummaryAffiliation: University of Melbourne Country: Australia Publications
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Detail Information
Publications
Potential role of odanacatib in the treatment of osteoporosisKong Wah Ng
Department of Endocrinology and Diabetes and St Vincent s Institute, St Vincent s Hospital, Fitzroy, Victoria, Australia
Clin Interv Aging 7:235-47. 2012..Ongoing studies are expected to provide information on the long-term efficacy in fracture reduction and safety of prolonged treatment with ODN...
Future developments in osteoporosis therapyK W Ng
Department of Endocrinology and Diabetes, The University of Melbourne, St Vincent s Hospital, Fitzroy, Victoria 3065, Australia
Endocr Metab Immune Disord Drug Targets 9:371-84. 2009..Any new therapy for osteoporosis must take into consideration its safety, efficacy, affordability and specificity of action...
Regulation of glucose metabolism and the skeletonKong Wah Ng
Department of Endocrinology and Diabetes, St Vincent s Hospital, Fitzroy, Vic, Australia
Clin Endocrinol (Oxf) 75:147-55. 2011..Data available from the limited number of clinical studies do not provide a sufficient body of evidence to determine whether osteocalcin or undercarboxylated osteocalcin affects glucose metabolism in humans...
A novel osteoblast-derived C-type lectin that inhibits osteoclast formationH Zhou
Department of Medicine, University of Melbourne, St Vincent s Hospital, and St Vincent s Institute of Medical Research, Fitzroy, Victoria 3065, Australia
J Biol Chem 276:14916-23. 2001..The overlapping tissue distribution of OCIL mRNA and protein with that of RANKL strongly suggests an interaction between these molecules in the skeleton and in extraskeletal tissues...
Localization of RANKL (receptor activator of NF kappa B ligand) mRNA and protein in skeletal and extraskeletal tissuesV Kartsogiannis
Department of Medicine, The University of Melbourne and St Vincent s Institute of Medical Research, St Vincent s Hospital, Fitzroy, Victoria, Australia
Bone 25:525-34. 1999..RANKL was also developmentally regulated, as evidenced by its expression in the intestine, liver, and lung at E15 and newborn mouse but not in the adult...
Low-intensity pulsed ultrasound stimulates a bone-forming response in UMR-106 cellsS J Warden
Centre for Sports Medicine Research and Education, School of Physiotherapy, University of Melbourne, Melbourne, Victoria, Australia
Biochem Biophys Res Commun 286:443-50. 2001..These findings suggest that low-intensity pulsed US has a direct effect on bone formation. This may contribute to the beneficial effect of low-intensity pulsed US on fracture repair...
Structure of the 5' flanking region of the gene encoding human parathyroid-hormone-related protein (PTHrP)L J Suva
St Vincent s Institute of Medical Research, Fitzroy, Australia
Gene 77:95-105. 1989..This analysis of the human PTHrP gene is the first report of a PTHrP gene for any species...
rHox: a homeobox gene expressed in osteoblastic cellsY Hu
Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, NSW, Australia
J Cell Biochem 59:486-97. 1995..These data suggest that rHox is a potent negative regulator of gene expression, although the specific role of rHox in bone gene regulation remains to be determined...
Expression of rat homeobox gene, rHOX, in developing and adult tissues in mice and regulation of its mRNA expression in osteoblasts by bone morphogenetic protein 2 and parathyroid hormone-related proteinY S Hu
Department of Medicine, The University of Melbourne, St Vincent s Hospital, Fitzroy, Victoria, Australia
Mol Endocrinol 12:1721-32. 1998..Furthermore, down-regulation of rHox mRNA by bone morphogenetic protein 2 and its up-regulation by PTHrP support a role of the homeodomain protein, rHox, in osteoblast differentiation...
