George A C Murrell

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. pmc Addition of nitric oxide through nitric oxide-paracetamol enhances healing rat achilles tendon
    George A C Murrell
    Orthopaedic Research Institute, St George Hospital, Research and Education Centre, University of New South Wales, Level 2, 4 10 South Street, Kogarah, Sydney, NSW, 2217, Australia
    Clin Orthop Relat Res 466:1618-24. 2008
  2. ncbi request reprint Treatment of shoulder dislocation: is a sling appropriate?
    George A C Murrell
    Department of Orthopaedic Surgery, St George Hospital, Kogarah, NSW 2217, Australia
    Med J Aust 179:370-1. 2003
  3. ncbi request reprint The rotator cuff functional index
    Daryl C Osbahr
    Department of Orthopaedic Surgery, St George Hospital Campus, 4 10, South Street, Kogarah, Sydney, New South Wales 2217, Australia
    Am J Sports Med 34:956-60. 2006
  4. ncbi request reprint Oxygen free radicals and tendon healing
    George A C Murrell
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    J Shoulder Elbow Surg 16:S208-14. 2007
  5. doi request reprint Frog glue enhances rotator cuff repair in a laboratory cadaveric model
    Neal L Millar
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Kogarah, New South Wales, Australia
    J Shoulder Elbow Surg 18:639-45. 2009
  6. ncbi request reprint Overexpression of antioxidant enzyme peroxiredoxin 5 protects human tendon cells against apoptosis and loss of cellular function during oxidative stress
    Jun Yuan
    Orthopaedic Research Institute, St George Hospital Campus, 4 10 South Street, University of New South Wales, Sydney, NSW 2217, Australia
    Biochim Biophys Acta 1693:37-45. 2004
  7. ncbi request reprint Topical glyceryl trinitrate treatment of chronic noninsertional achilles tendinopathy. A randomized, double-blind, placebo-controlled trial
    Justin A Paoloni
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, New South Wales, Australia
    J Bone Joint Surg Am 86:916-22. 2004
  8. ncbi request reprint Gene expression changes in SNAP-stimulated and iNOS-transfected tenocytes--expression of extracellular matrix genes and its implications for tendon-healing
    Timothy J Molloy
    Orthopaedic Research Institute, St George Hospital, University of New South Wales, Kogarah, Sydney, NSW 2217, Australia
    J Orthop Res 24:1869-82. 2006
  9. doi request reprint Long-term outcomes after arthroscopic capsular release for idiopathic adhesive capsulitis
    Hugh M J Le Lievre
    Orthopaedic Research Institute, St George Hospital, University of New South Wales, Kogarah NSW 2217, Australia
    J Bone Joint Surg Am 94:1208-16. 2012
  10. ncbi request reprint Nitric oxide enhances collagen synthesis in cultured human tendon cells
    Wei Xia
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Kogarah, Sydney, New South Wales 2217, Australia
    J Orthop Res 24:159-72. 2006

Collaborators

  • Neal L Millar
  • James Linklater
  • Michael Muller
  • Sjoerd Rutten
  • Karin S Peters
  • Craig Harris
  • Ali R Bokhari
  • Fang Wang
  • Craig A Cummins
  • Karen A Ginn
  • Brett M Andres
  • Yasemin Baldik
  • Daryl C Osbahr
  • J A Paoloni
  • Judie Walton
  • Yinghua Xu
  • Jun Yuan
  • Kimberley Hayes
  • Anastasios Paxinos
  • Min Xia Wang
  • Mya Lay Sein
  • Yao Wang
  • Anthony Tzannes
  • Judie R Walton
  • Fiona Bonar
  • Wei Xia
  • Hilary L Malcarney
  • Elizabeth R X Tham
  • Lisa Briggs
  • Hugh M J Le Lievre
  • Xiao L Wu
  • Sebastian D A McCallum
  • Zoltan Szomor
  • Annette Trickett
  • Mary Callanan
  • Brent Kirkbride
  • Donald Kuah
  • Richard Appleyard
  • Timothy J Molloy
  • Shiyi Chen
  • Divya Bhargav Diwan
  • Sanjeev Mahajan
  • Stephen P Oakley
  • Bernard Knoops
  • Hugh P Jones
  • Carl Bryant
  • Quan Dai
  • Zoltan L Szomor
  • Ron Shnier
  • Lawrence Bryant
  • Jason L Koh
  • Wei Zhu
  • Shanshan Wu
  • Tej Dugal
  • Yasser Khatib
  • Nicholas K Bowman
  • Charles E de Bock
  • Pieter Stijn Haen
  • Jeanette Marshall
  • Richard Quinn
  • Marie Landtmeters
  • Bruce W Kirkham
  • Charles de Bock
  • Richard C Appleyard
  • Marissa N Lassere
  • Ian Portek
  • Allen Turnbull
  • Laura Manfield
  • Edith M Gardiner
  • Ashish D Diwan
  • Aiqun Wei
  • Jianhao Lin
  • Russell F Warren
  • Ai Qun Wei

Detail Information

Publications59

  1. pmc Addition of nitric oxide through nitric oxide-paracetamol enhances healing rat achilles tendon
    George A C Murrell
    Orthopaedic Research Institute, St George Hospital, Research and Education Centre, University of New South Wales, Level 2, 4 10 South Street, Kogarah, Sydney, NSW, 2217, Australia
    Clin Orthop Relat Res 466:1618-24. 2008
    ....
  2. ncbi request reprint Treatment of shoulder dislocation: is a sling appropriate?
    George A C Murrell
    Department of Orthopaedic Surgery, St George Hospital, Kogarah, NSW 2217, Australia
    Med J Aust 179:370-1. 2003
    ..Shoulder dislocations, if managed non-operatively, should not be treated by placing arms in a sling. Rather, placing them in a splint or using a pillow so that the the arm is externally rotated should be considered...
  3. ncbi request reprint The rotator cuff functional index
    Daryl C Osbahr
    Department of Orthopaedic Surgery, St George Hospital Campus, 4 10, South Street, Kogarah, Sydney, New South Wales 2217, Australia
    Am J Sports Med 34:956-60. 2006
    ..Despite improvements in the clinical assessment of rotator cuff injuries, shortcomings exist in diagnosing rotator cuff tears...
  4. ncbi request reprint Oxygen free radicals and tendon healing
    George A C Murrell
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    J Shoulder Elbow Surg 16:S208-14. 2007
    ..In all 3 clinical trials, there was a significant positive beneficial effect of nitric oxide donation to the clinical symptoms and function of patients with Achilles tendinopathy, tennis elbow, and supraspinatus tendinitis...
  5. doi request reprint Frog glue enhances rotator cuff repair in a laboratory cadaveric model
    Neal L Millar
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Kogarah, New South Wales, Australia
    J Shoulder Elbow Surg 18:639-45. 2009
    ..The unique properties of this frog glue (strong, flexible and sets in water) may ultimately lead to its use as an adjunct to rotator cuff repair in humans. LEVEL OF EVIDENCE: Basic science study...
  6. ncbi request reprint Overexpression of antioxidant enzyme peroxiredoxin 5 protects human tendon cells against apoptosis and loss of cellular function during oxidative stress
    Jun Yuan
    Orthopaedic Research Institute, St George Hospital Campus, 4 10 South Street, University of New South Wales, Sydney, NSW 2217, Australia
    Biochim Biophys Acta 1693:37-45. 2004
    ..Results from our study indicate that the antioxidant enzyme PRDX5 plays a protective role in human tendon cells against oxidative stress by reducing apoptosis and maintaining collagen synthesis...
  7. ncbi request reprint Topical glyceryl trinitrate treatment of chronic noninsertional achilles tendinopathy. A randomized, double-blind, placebo-controlled trial
    Justin A Paoloni
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, New South Wales, Australia
    J Bone Joint Surg Am 86:916-22. 2004
    ..The goal of the present study was to determine if topical glyceryl trinitrate improves clinical outcome measures in patients with Achilles tendinopathy...
  8. ncbi request reprint Gene expression changes in SNAP-stimulated and iNOS-transfected tenocytes--expression of extracellular matrix genes and its implications for tendon-healing
    Timothy J Molloy
    Orthopaedic Research Institute, St George Hospital, University of New South Wales, Kogarah, Sydney, NSW 2217, Australia
    J Orthop Res 24:1869-82. 2006
    ..These findings will be of use when optimizing the dose of NO delivery in further work investigating NO as potential treatment of tendon injuries...
  9. doi request reprint Long-term outcomes after arthroscopic capsular release for idiopathic adhesive capsulitis
    Hugh M J Le Lievre
    Orthopaedic Research Institute, St George Hospital, University of New South Wales, Kogarah NSW 2217, Australia
    J Bone Joint Surg Am 94:1208-16. 2012
    ....
  10. ncbi request reprint Nitric oxide enhances collagen synthesis in cultured human tendon cells
    Wei Xia
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Kogarah, Sydney, New South Wales 2217, Australia
    J Orthop Res 24:159-72. 2006
    ..These results may explain, in part, at least, the beneficial effects of NO donors in animal models and during the treatment of tendonopathies in human clinical trials. ...
  11. doi request reprint Shoulder pain in elite swimmers: primarily due to swim-volume-induced supraspinatus tendinopathy
    Mya Lay Sein
    Orthopaedic Research Institute, University of New South Wales, St George Hospital, Australia
    Br J Sports Med 44:105-13. 2010
    ..HYPOTHESIS/STUDY DESIGN: The authors used a cross-sectional study design to test Jobe's hypothesis that repetitive forceful swimming leads to shoulder laxity, which in turn leads to impingement pain...
  12. ncbi request reprint Topical glyceryl trinitrate application in the treatment of chronic supraspinatus tendinopathy: a randomized, double-blinded, placebo-controlled clinical trial
    Justin A Paoloni
    Orthopaedic Research Institute, Research and Education Centre, St George Hospital, 2nd Floor, 4 South Street, Kogarah, Sydney, 2217 Australia
    Am J Sports Med 33:806-13. 2005
    ..Topical glyceryl trinitrate therapy has previously demonstrated short-term pain reduction in patients with supraspinatus tendinopathy...
  13. ncbi request reprint Diagnostic values of tests for acromioclavicular joint pain
    Judie Walton
    Sports Medicine and Shoulder Service, Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Kogarah, Sydney, New South Wales 2217, Australia
    J Bone Joint Surg Am 86:807-12. 2004
    ..This prospective study was performed to determine which clinical and imaging tests were most helpful for diagnosing acromioclavicular joint pain...
  14. ncbi request reprint An evaluation of the effects of the extent of capsular release and of postoperative therapy on the temporal outcomes of adhesive capsulitis
    Divya Bhargav Diwan
    Sports Medicine and Shoulder Service, Orthopedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    Arthroscopy 21:1105-13. 2005
    ..To evaluate effects of the extent of surgical release and of postoperative physiotherapy on the outcomes of this procedure...
  15. pmc Open versus two forms of arthroscopic rotator cuff repair
    Neal L Millar
    Department of Orthopaedic Surgery, Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, 4 10 South Street, Kogarah, Sydney, NSW 2217, Australia
    Clin Orthop Relat Res 467:966-78. 2009
    ..An intact cuff on ultrasound corresponded to better results for supraspinatus strength, patient outcomes, and rotator cuff functional ability...
  16. doi request reprint Repair of partial-thickness rotator cuff tears: a biomechanical analysis of footprint contact pressure and strength in an ovine model
    Karin S Peters
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    Arthroscopy 26:877-84. 2010
    ..The purpose of this study was to determine whether transtendon repair by use of a novel small-diameter knotless anchor showed enhanced mechanical properties compared with tear completion and repair...
  17. ncbi request reprint Arthroscopic stabilization of superior labral (SLAP) tears with biodegradable tack: outcomes to 2 years
    Anastasios Paxinos
    Sports Medicine and Shoulder Service and Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    Arthroscopy 22:627-34. 2006
    ..This prospective study aimed to document the pain and functional outcomes, over time, of patients whose SLAP lesions had been repaired with biodegradable tacks...
  18. ncbi request reprint Involvement of cytochrome c release and caspase-3 activation in the oxidative stress-induced apoptosis in human tendon fibroblasts
    Jun Yuan
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, 4 10 South Street, Sydney, NSW 2217, Australia
    Biochim Biophys Acta 1641:35-41. 2003
    ..The data suggest that oxidative stress-induced apoptosis in human tendon fibroblasts is mediated via pathway(s) that includes release of cytochrome c from mitochondria to the cytosol and activation of caspase-3...
  19. doi request reprint Enhanced expression of neuronal proteins in idiopathic frozen shoulder
    Yinghua Xu
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, NSW, Australia
    J Shoulder Elbow Surg 21:1391-7. 2012
    ..Our understanding of the pathogenesis of frozen shoulder and why it is so painful is undetermined. This study investigated the expression of neuronal proteins in the capsular tissue of frozen shoulder...
  20. doi request reprint Neoinnervation in rotator cuff tendinopathy
    Yinghua Xu
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, NSW, Australia
    Sports Med Arthrosc 19:354-9. 2011
    ..These data support the hypothesis that early tendinopathy is associated with increases of newly grown nerve fibers and blood vessels inside and around tendinopathic tendon, and these may be the source of pain in tendinopathy...
  21. ncbi request reprint Three-year followup study of topical glyceryl trinitrate treatment of chronic noninsertional Achilles tendinopathy
    Justin Alan Paoloni
    University of New South Wales, Orthopaedic Research Institute, 2nd Floor, 4 10 South St, Kogarah, Sydney, NSW, Australia
    Foot Ankle Int 28:1064-8. 2007
    ..No long-term followup is reported. We aimed to assess if the demonstrated efficacy of this treatment persisted 3 years after discontinuation of therapy...
  22. ncbi request reprint Expression of urokinase-type plasminogen activator and its receptor is up-regulated during tendon healing
    Wei Xia
    Orthopaedic Research Institute, The St George Hospital, University of New South Wales, Kogarah, Sydney, NSW 2217, Australia
    J Orthop Res 21:819-25. 2003
    ..These findings show for the first time that uPA, and especially its receptor uPAR, are up-regulated during tendon healing...
  23. pmc Heat shock protein and apoptosis in supraspinatus tendinopathy
    Neal L Millar
    Orthopaedic Research Institute, Department of Orthopaedic Surgery, St George Hospital Campus, University of New South Wales, 4 10 South Street, Kogarah, NSW, 2217, Australia
    Clin Orthop Relat Res 466:1569-76. 2008
    ..This finding suggests heat shock proteins play a role in the cascade of stress-activated programmed cell death and degeneration in tendinopathy and may provide a novel target in preventing tendinopathies...
  24. pmc Using nitric oxide to treat tendinopathy
    George A C Murrell
    Orthopaedic Research Institute, University of New South Wales, The St George Hospital, Kogarah, Sydney, New South Wales 2217, Australia
    Br J Sports Med 41:227-31. 2007
    ..In humans, in three randomised clinical trials, we have shown that NO delivered via a transdermal patch enhances the subjective and objective recovery of patients with tennis elbow, Achilles tendinosis and supraspinatus tendinosis...
  25. ncbi request reprint Oxidative stress-induced c-Jun N-terminal kinase (JNK) activation in tendon cells upregulates MMP1 mRNA and protein expression
    Fang Wang
    Orthopaedic Research Institute, St George Hospital, University of New South Wales, ORI Level 2, 4 10 South Street, Kogarah, NSW 2217, Sydney, Australia
    J Orthop Res 25:378-89. 2007
    ..Results from the current study indicated that stress activated JNK plays an important role in tendon matrix degradation, possibly through upregulating of MMP1...
  26. doi request reprint The role of nitric oxide in tendon healing
    Ali R Bokhari
    Orthopaedic Research Institute, University of New South Wales, The St George Hospital, Sydney, NSW, Australia
    J Shoulder Elbow Surg 21:238-44. 2012
    ..The use of a new GTN patch, OrthoDerm, demonstrated no evidence for efficacy in treating chronic lateral epicondylitis...
  27. ncbi request reprint Restore orthobiologic implant: not recommended for augmentation of rotator cuff repairs
    Judie R Walton
    Sports Medicine and Shoulder Service, Orthopaedic Research Institute, University of New South Wales, St George Hospital, Sydney, New South Wales, Australia
    J Bone Joint Surg Am 89:786-91. 2007
    ..We carried out a study to determine whether patients who received this xenograft to augment a rotator cuff repair exhibited greater shoulder strength, shoulder function, and/or resistance to retearing...
  28. ncbi request reprint A randomised clinical trial evaluating the efficacy of physiotherapy after rotator cuff repair
    Kimberley Hayes
    St George Hospital, University of New South Wales, Australia
    Aust J Physiother 50:77-83. 2004
    ..On the basis of these results, outcomes for subjects allocated to individualised physiotherapy treatment after rotator cuff repair are no better than for subjects allocated to a standardised home exercise regime...
  29. doi request reprint Five-year prospective comparison study of topical glyceryl trinitrate treatment of chronic lateral epicondylosis at the elbow
    Sebastian D A McCallum
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    Br J Sports Med 45:416-20. 2011
    ..Topical glyceryl trinitrate (GTN) treatment has previously demonstrated short-term efficacy in the treatment of lateral epicondylosis. No long-term follow-up has been performed...
  30. ncbi request reprint An assessment of the interexaminer reliability of tests for shoulder instability
    Anthony Tzannes
    Sports Medicine and Shoulder Service, Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    J Shoulder Elbow Surg 13:18-23. 2004
    ....
  31. pmc Reliability of MRI assessment of supraspinatus tendinopathy
    Mya Lay Sein
    Orthopaedic Research Institute, University of New South Wales, St George Hospital, Sydney, New South Wales, Australia
    Br J Sports Med 41:e9. 2007
    ..To determine the interobserver and intraobserver reliability of the interpretation of MRIs for supraspinatus tendinosis...
  32. ncbi request reprint Deletion of iNOS gene impairs mouse fracture healing
    Yasemin Baldik
    Orthopaedic Research Institute, St George Hospital, 4 10 South Street, University of New South Wales, Kogarah, Sydney, NSW 2217, Australia
    Bone 37:32-6. 2005
    ..These data indicate that iNOS is important in mouse fracture healing. However, the clinical utility of NOS gene therapy to enhance fracture healing will need further evaluation...
  33. ncbi request reprint Adenovirus-mediated gene transfer to healing tendon--enhanced efficiency using a gelatin sponge
    Quan Dai
    The Orthopaedic Research Institute, University of New South Wales, St George Hospital Campus, Sydney, NSW, Australia
    J Orthop Res 21:604-9. 2003
    ..The results demonstrate that adenovirus can be used to deliver a gene of interest to cultured human rotator cuff tendon cells and healing tendon, with gelatin sponge implantation enhancing adenoviral transfection efficiency in vivo...
  34. ncbi request reprint Meniscal and chondral loss in the anterior cruciate ligament injured knee
    Hugh P Jones
    Department of Orthopaedic Surgery, St George Hospital Campus, Kogarah, New South Wales, Australia
    Sports Med 33:1075-89. 2003
    ....
  35. ncbi request reprint Cell death and tendinopathy
    Jun Yuan
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, NSW 2217, Australia
    Clin Sports Med 22:693-701. 2003
    ....
  36. ncbi request reprint The Orthopaedic Research Institute-Tennis Elbow Testing System: A modified chair pick-up test-interrater and intrarater reliability testing and validity for monitoring lateral epicondylosis
    Justin A Paoloni
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Australia
    J Shoulder Elbow Surg 13:72-7. 2004
    ..This system could be used for routine clinical monitoring of patients with lateral epicondylosis...
  37. doi request reprint Intraoperative determinants of rotator cuff repair integrity: an analysis of 500 consecutive repairs
    Xiao L Wu
    Sports Medicine and Shoulder Service, St George Hospital Campus, University of New South Wales, Sydney, Australia
    Am J Sports Med 40:2771-6. 2012
    ..Patients with an intact rotator cuff 6 months after surgery have better subjective and objective outcomes at 6 months and 2 years after rotator cuff repair than those who do not have an intact repair...
  38. ncbi request reprint Apoptosis in rotator cuff tendonopathy
    Jun Yuan
    Orthopaedic Research Institute, St George Hospital Campus, 4 10 South Street, University of New, South Wales, Sydney, NSW 2217, Australia
    J Orthop Res 20:1372-9. 2002
    ..Cells undergoing apoptosis in rotator cuff were mainly fibroblast-like cells. These finding indicate that apoptosis may play an important role in the pathogenesis of rotator cuff degeneration...
  39. ncbi request reprint The rotator cuff: biological adaptations to its environment
    Hilary L Malcarney
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Kogarah, New South Wales, Australia
    Sports Med 33:993-1002. 2003
    ..While many of these characteristics appear to be adaptive and occur in the healthy rotator cuff, some may predispose the tendon complex to pathology...
  40. ncbi request reprint Early inflammatory reaction after rotator cuff repair with a porcine small intestine submucosal implant: a report of 4 cases
    Hilary L Malcarney
    Department of Orthopaedic Surgery, St George Hospital, University of New South Wales, Sydney, Australia
    Am J Sports Med 33:907-11. 2005
    ..Porcine small intestine submucosal grafts have been successful in enhancing soft tissue repair, as demonstrated by animal studies. Currently, there are no reports of the use of such implants in human rotator cuff repair...
  41. ncbi request reprint Rotator cuff repair with bioabsorbable screws: An in vivo and ex vivo investigation
    Craig A Cummins
    Orthopaedic Research Institute, Kogarah, Australia
    Arthroscopy 19:239-48. 2003
    ..Type of Study: In vivo clinical outcomes investigation, and ex vivo biomechanical study...
  42. ncbi request reprint Accuracy and reliability of arthroscopic estimates of cartilage lesion size in a plastic knee simulation model
    Stephen P Oakley
    Deptartments of Rheumatology, St George Hospital Campus, University of New South Wales, New South Wales, Australia
    Arthroscopy 19:282-9. 2003
    ..A second goal was to determine the effect of lesion location within the knee and lesion size on accuracy and reliability. Type of Study: Cross-sectional study of arthroscopic estimates of cartilage lesion size...
  43. pmc Treatment of tendinopathy: what works, what does not, and what is on the horizon
    Brett M Andres
    Orthopaedic Research Institute, St George Hospital, University of New South Wales, Level 2 Research and Education Building, 4 10 South Street, Kogarah, Sydney, NSW, 2217, Australia
    Clin Orthop Relat Res 466:1539-54. 2008
    ..Surgery remains the last option due to the morbidity and inconsistent outcomes. The ideal treatment for tendinopathy remains unclear. LEVEL OF EVIDENCE: Level II, systematic review...
  44. doi request reprint Ultrasound changes after rotator cuff repair: is supraspinatus tendon thickness related to pain?
    Elizabeth R X Tham
    Orthopaedic Research Institute, St George Hospital, Kogarah, NSW 2217, Australia
    J Shoulder Elbow Surg 22:e8-15. 2013
    ....
  45. ncbi request reprint Shoulder instability: management and rehabilitation
    Kimberley Hayes
    Sports Medicine and Shoulder Service, Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    J Orthop Sports Phys Ther 32:497-509. 2002
    ..This paper reviews the nonoperative treatment and the postoperative management of patients with various classifications of shoulder instability...
  46. ncbi request reprint Expression and regulation of peroxiredoxin 5 in human osteoarthritis
    Min Xia Wang
    Orthopaedic Research Institute, St George Hospital, University of New South Wales, Sydney, NSW, Australia
    FEBS Lett 531:359-62. 2002
    ..The present study suggests that PRDX5 may play a protective role against oxidative stress in human cartilage...
  47. pmc The basic science of tendinopathy
    Yinghua Xu
    Orthopaedic Research Institute, The St George Hospital, University of New South Wales, Level 2, 4 10 South Street, Kogarah, Sydney, NSW, 2217, Australia
    Clin Orthop Relat Res 466:1528-38. 2008
    ..The management strategies might involve agents or cells that induce tendon stem cell proliferation, repair and restoration of matrix integrity...
  48. ncbi request reprint Topical nitric oxide application in the treatment of chronic extensor tendinosis at the elbow: a randomized, double-blinded, placebo-controlled clinical trial
    Justin A Paoloni
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, New South Wales, Australia
    Am J Sports Med 31:915-20. 2003
    ..No treatment has been universally successful. Topical application of nitric oxide has been used effectively to treat fractures and cutaneous wounds in animal models, presumably by stimulation of collagen synthesis in fibroblasts...
  49. ncbi request reprint Identification of prognostic indicators for patient outcomes in extensor tendinopathy at the elbow
    Justin A Paoloni
    Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Kogarth, Sydney, NSW, Australia
    Scand J Med Sci Sports 14:163-7. 2004
    ..Enforced rest has monetary and quality-of-life implications, but is probably preferable to an incomplete recovery and prolonged tendon pain and dysfunction...
  50. ncbi request reprint Localization of nitric oxide synthases during fracture healing
    Wei Zhu
    Orthopedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    J Bone Miner Res 17:1470-7. 2002
    ..In summary, the,expression of NOS isoforms during fracture healing was time dependent and cellular distinctive...
  51. ncbi request reprint Reliability of 3 methods for assessing shoulder strength
    Kimberley Hayes
    Department of Orthopaedic Surgery, St George Hospital Campus, University of New South Wales, Kogarah 2217, Sydney, NSW Australia
    J Shoulder Elbow Surg 11:33-9. 2002
    ..002). In summary, the handheld dynamometer was the most reliable and discriminatory means for assessing strength of the rotator cuff in symptomatic subjects...
  52. ncbi request reprint Clinical examination of the unstable shoulder
    Anthony Tzannes
    Sports Medicine and Shoulder Service, Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, New South Wales, Australia
    Sports Med 32:447-57. 2002
    ..The apprehension sign and its variations (augmentation, relocation and release) have reasonable inter-examiner reliability (intraclass correlation coefficient 0.5 to 0.7) and are highly predictive for anterior instability (LR 8 to 100)...
  53. ncbi request reprint The unstable shoulder in the adolescent athlete
    Judie Walton
    Sports Medicine and Shoulder Service and the Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, Australia
    Am J Sports Med 30:758-67. 2002
    ..The aim of rehabilitation is to enhance the dynamic muscular and proprioceptive restraints to shoulder instability...
  54. ncbi request reprint A comparison of clinical estimation, ultrasonography, magnetic resonance imaging, and arthroscopy in determining the size of rotator cuff tears
    Lawrence Bryant
    St George Hospital Campus, University of New South Wales, Sydney, Australia
    J Shoulder Elbow Surg 11:219-24. 2002
    ..41; P =.02) than the other methods. Each method underestimated rotator cuff tear size by 12%, 30%, 33%, and 38%, respectively. No method was able to determine the size of partial-thickness rotator cuff tears (r < 0.02)...
  55. ncbi request reprint Supplementation of rotator cuff repair with a bioresorbable scaffold
    Jason L Koh
    Department of Orthopaedic Surgery, Northwestern University Medical School, 645 North Michigan Avenue, Chicago, IL 60611, USA
    Am J Sports Med 30:410-3. 2002
    ..Repair of a torn rotator cuff should have sufficient initial strength of the fixation to permit appropriate rehabilitation...
  56. ncbi request reprint Interferon-alpha (Intron A) upregulates urokinase-type plasminogen activator receptor gene expression
    Shanshan Wu
    Division of Molecular Medicine, John Curtin School of Medical Research, The Australian National University, G P O Box 334, Canberra, ACT 0200, Australia
    Cancer Immunol Immunother 51:248-54. 2002
    ..Both sodium butyrate and amiloride inhibited the uPAR mRNA levels induced by IFN-alpha or IFN-gamma. These results may provide useful information for the treatment of patients receiving IFN-alpha or IFN-gamma...
  57. ncbi request reprint Mode of failure for rotator cuff repair with suture anchors identified at revision surgery
    Craig A Cummins
    Lake Cook Orthopaedic Associates, Barrington, IL 60010, USA
    J Shoulder Elbow Surg 12:128-33. 2003
    ..This suggests that the weak link in rotator cuff repairs with suture anchors and horizontal mattress sutures, as determined at revision surgery, is the tendon-suture interface...
  58. ncbi request reprint Rotator cuff repair: an ex vivo analysis of suture anchor repair techniques on initial load to failure
    Craig A Cummins
    Lake Cook Orthopedic Associates, Barrington, Illinois, USA
    Arthroscopy 21:1236-41. 2005
    ..To determine the best combination of anchors and suture techniques for repairing torn rotator cuff tendons...
  59. ncbi request reprint The effects of thermal capsular shrinkage on the outcomes of arthroscopic stabilization for primary anterior shoulder instability
    Shiyi Chen
    Department of Orthopaedic Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China
    Am J Sports Med 33:705-11. 2005
    ..The effectiveness of arthroscopic thermal capsulorrhaphy in the prevention of recurrent instability in primary anterior stabilization is undetermined...