Genomes and Genes
Michael J Murray
Affiliation: University of Melbourne
- Regulation of Drosophila mesoderm migration by phosphoinositides and the PH domain of the Rho GTP exchange factor PebbleMichael J Murray
Research School of Biology, Australian National University, ACT 2601, Australia
Dev Biol 372:17-27. 2012..Taken together, our results support a model in which interaction of the PH-domain of Pbl with PtdIns(4,5)P2 helps localise it to the plasma membrane which is important for mesoderm migration...
- Snail-dependent repression of the RhoGEF pebble is required for gastrulation consistency in Drosophila melanogasterMichael J Murray
Research School of Biology, Australian National University, ACT 2601, Canberra, Australia
Dev Genes Evol 222:361-8. 2012..We conclude that pbl levels are precisely regulated to ensure that there is enough protein available for its role in early mesoderm development but not so much as to inhibit the orderly progression of gastrulation...
- Photoactivatable GFP resolves Drosophila mesoderm migration behaviourMichael J Murray
The ARC Special Research Centre for the Molecular Genetics of Development and Molecular Genetics and Evolution Group, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
Development 134:3975-83. 2007..These characterisations pave the way for a more detailed analysis of gene function during early mesoderm development...
- The epithelial-mesenchymal transition of the Drosophila mesoderm requires the Rho GTP exchange factor PebbleMasha Smallhorn
Centre for the Molecular Genetics of Development and Research School of Biological Sciences, The Australian National University, Canberra, ACT, 0200, Australia
Development 131:2641-51. 2004..These studies reveal that a novel PBL-mediated intracellular signalling pathway operates in mesodermal cells during the transition from an epithelial to migratory mesenchymal morphology during gastrulation...
- Imaging pluripotent cell migration in DrosophilaMichael J Murray
Molecular Genetics and Evolution, Research School of Biological Sciences, Australian National University, Acton, ACT, Australia
Methods Mol Biol 750:169-84. 2011..Here, we review previous studies of the migration of pluripotent embryonic cells and describe, in detail, methods for visualising these cells...