T A Mori

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi request reprint Effect of eicosapentaenoic acid and docosahexaenoic acid on oxidative stress and inflammatory markers in treated-hypertensive type 2 diabetic subjects
    Trevor A Mori
    Department of Medicine, The University of Western Australia, The West Australian Heart Research Institute and The Western Australian Institute for Medical Research, Perth, Western Australia 6000, Australia
    Free Radic Biol Med 35:772-81. 2003
  2. ncbi request reprint Omega-3 fatty acids and inflammation
    Trevor A Mori
    School of Medicine and Pharmacology Royal Perth Hospital Unit, The University of Western Australia, Medical Research Foundation Building, Perth, Western Australia 6847, Australia
    Curr Atheroscler Rep 6:461-7. 2004
  3. ncbi request reprint Effect of fish and fish oil-derived omega-3 fatty acids on lipid oxidation
    Trevor A Mori
    School of Medicine and Pharmacology, The University of Western Australia, Medical Research Foundation Building, Box X 2213 GPO, Perth, Western Australia 6847, Australia
    Redox Rep 9:193-7. 2004
  4. ncbi request reprint Long-chain omega 3 fatty acids, blood lipids and cardiovascular risk reduction
    T A Mori
    Department of Medicine, University of Western Australia and the West Australian Heart Research Institute HeartSearch, Perth, Australia
    Curr Opin Lipidol 12:11-7. 2001
  5. ncbi request reprint Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight men
    T A Mori
    Department of Medicine, University of Western Australia, and The West Australian Heart Research Institute, Perth, Australia
    Circulation 102:1264-9. 2000
  6. ncbi request reprint Effect of omega 3 fatty acids on oxidative stress in humans: GC-MS measurement of urinary F2-isoprostane excretion
    T A Mori
    Department of Medicine and the West Australian Heart Research Institute, University of Western Australia, Perth, Australia
    Redox Rep 5:45-6. 2000
  7. ncbi request reprint Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men
    T A Mori
    Department of Medicine, The University of Western Australia and The West Australian Heart Research Institute, Perth
    Am J Clin Nutr 71:1085-94. 2000
  8. ncbi request reprint Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans
    T A Mori
    Department of Medicine, University of Western Australia, and The West Australian Heart Research Institute, Perth, Australia
    Hypertension 34:253-60. 1999
  9. ncbi request reprint Interactions between dietary fat, fish, and fish oils and their effects on platelet function in men at risk of cardiovascular disease
    T A Mori
    Department of Medicine, University of Western Australia, Perth, Western Australia
    Arterioscler Thromb Vasc Biol 17:279-86. 1997
  10. ncbi request reprint Effect of fish diets and weight loss on serum leptin concentration in overweight, treated-hypertensive subjects
    Trevor A Mori
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western, Australia
    J Hypertens 22:1983-90. 2004

Detail Information

Publications105 found, 100 shown here

  1. ncbi request reprint Effect of eicosapentaenoic acid and docosahexaenoic acid on oxidative stress and inflammatory markers in treated-hypertensive type 2 diabetic subjects
    Trevor A Mori
    Department of Medicine, The University of Western Australia, The West Australian Heart Research Institute and The Western Australian Institute for Medical Research, Perth, Western Australia 6000, Australia
    Free Radic Biol Med 35:772-81. 2003
    ..This study is the first report demonstrating that either EPA or DHA reduce in vivo oxidant stress without changing markers of inflammation, in treated hypertensive, type 2 diabetic subjects...
  2. ncbi request reprint Omega-3 fatty acids and inflammation
    Trevor A Mori
    School of Medicine and Pharmacology Royal Perth Hospital Unit, The University of Western Australia, Medical Research Foundation Building, Perth, Western Australia 6847, Australia
    Curr Atheroscler Rep 6:461-7. 2004
    ..Given the evidence relating progression of atherosclerosis to chronic inflammation, the n-3 fatty acids may play an important role via modulation of the inflammatory processes...
  3. ncbi request reprint Effect of fish and fish oil-derived omega-3 fatty acids on lipid oxidation
    Trevor A Mori
    School of Medicine and Pharmacology, The University of Western Australia, Medical Research Foundation Building, Box X 2213 GPO, Perth, Western Australia 6847, Australia
    Redox Rep 9:193-7. 2004
    ..In this regard, our findings using the measurement of F(2)-isoprostanes, a reliable measure of in vivo lipid peroxidation and oxidant stress, do not support adverse effects of omega3 fatty acids on lipid peroxidation...
  4. ncbi request reprint Long-chain omega 3 fatty acids, blood lipids and cardiovascular risk reduction
    T A Mori
    Department of Medicine, University of Western Australia and the West Australian Heart Research Institute HeartSearch, Perth, Australia
    Curr Opin Lipidol 12:11-7. 2001
    ..On the basis of our current knowledge, we believe it is justified to recommend, particularly to high-risk populations, an increased dietary intake of omega 3 fatty acids through the consumption of fish...
  5. ncbi request reprint Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight men
    T A Mori
    Department of Medicine, University of Western Australia, and The West Australian Heart Research Institute, Perth, Australia
    Circulation 102:1264-9. 2000
    ..We investigated possible differences in the effects of purified EPA or DHA on forearm vascular reactivity in overweight hyperlipidemic men that might contribute to the blood pressure-lowering effects of fish oils...
  6. ncbi request reprint Effect of omega 3 fatty acids on oxidative stress in humans: GC-MS measurement of urinary F2-isoprostane excretion
    T A Mori
    Department of Medicine and the West Australian Heart Research Institute, University of Western Australia, Perth, Australia
    Redox Rep 5:45-6. 2000
    ..In both trials, urinary F2-isoprostanes were significantly reduced by 20-27%. Therefore, in contrast with previous reports in the literature, these results demonstrate that omega3 fatty acids reduce in vivo oxidant stress in humans...
  7. ncbi request reprint Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men
    T A Mori
    Department of Medicine, The University of Western Australia and The West Australian Heart Research Institute, Perth
    Am J Clin Nutr 71:1085-94. 2000
    ..Regular consumption of n-3 fatty acids of marine origin can improve serum lipids and reduce cardiovascular risk...
  8. ncbi request reprint Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans
    T A Mori
    Department of Medicine, University of Western Australia, and The West Australian Heart Research Institute, Perth, Australia
    Hypertension 34:253-60. 1999
    ..These results have important implications for human nutrition and the food industry...
  9. ncbi request reprint Interactions between dietary fat, fish, and fish oils and their effects on platelet function in men at risk of cardiovascular disease
    T A Mori
    Department of Medicine, University of Western Australia, Perth, Western Australia
    Arterioscler Thromb Vasc Biol 17:279-86. 1997
    ....
  10. ncbi request reprint Effect of fish diets and weight loss on serum leptin concentration in overweight, treated-hypertensive subjects
    Trevor A Mori
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western, Australia
    J Hypertens 22:1983-90. 2004
    ..A recent population study suggested that dietary-derived omega3 fatty acids lower leptin levels independent of body fat...
  11. ncbi request reprint The independent and combined effects of aerobic exercise and dietary fish intake on serum lipids and glycemic control in NIDDM. A randomized controlled study
    D W Dunstan
    Department of Medicine, Royal Perth Hospital, University of Western Australia, Australia
    Diabetes Care 20:913-21. 1997
    ..The present study examined the effects of moderate aerobic exercise and the incorporation of fish into a low-fat (30% total energy) diet on serum lipids and glycemic control in dyslipidemic NIDDM patients...
  12. doi request reprint Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial
    R Belski
    School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
    Int J Obes (Lond) 35:810-9. 2011
    ..Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre...
  13. ncbi request reprint Supplementation with vitamins C, E, beta-carotene and selenium has no effect on anti-oxidant status and immune responses in allergic adults: a randomized controlled trial
    J A Dunstan
    School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia
    Clin Exp Allergy 37:180-7. 2007
    ..The aim of this study in adults was to determine the effects of dietary anti-oxidants on allergen-specific immune responses in sensitized individuals...
  14. doi request reprint Postnatal fish oil supplementation in high-risk infants to prevent allergy: randomized controlled trial
    N D'Vaz
    School of Paediatrics and Child Health Research SPACH, Princess Margaret Hospital, University of Western Australia, PO Box D184, Perth, Western Australia, 6001 Australia
    Pediatrics 130:674-82. 2012
    ..The objective of this study was to assess the effect of fish oil n-3 PUFA supplementation from birth to 6 months of age on infant allergic disease...
  15. ncbi request reprint Effects of n-3 polyunsaturated fatty acid supplementation in pregnancy on maternal and fetal erythrocyte fatty acid composition
    J A Dunstan
    School of Paediatrics and Child Health, University of Western Australia, Perth, Western Australia, Australia
    Eur J Clin Nutr 58:429-37. 2004
    ....
  16. doi request reprint Effects of increasing dietary protein and fibre intake with lupin on body weight and composition and blood lipids in overweight men and women
    J M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, and the WAIMR Centre for Food and Genomic Medicine, Perth, Western Australia, Australia
    Int J Obes (Lond) 34:1086-94. 2010
    ..In addition, several studies have suggested that lupin may reduce cholesterol concentrations and benefit glucose and insulin metabolism...
  17. ncbi request reprint Acute effects of ingestion of black and green tea on lipoprotein oxidation
    J M Hodgson
    University of Western Australia, Department of Medicine, and The West Australian Heart Research Institute, Royal Perth Hospital, Perth, Australia
    Am J Clin Nutr 71:1103-7. 2000
    ..The absence of effects in previous studies may be due to the isolation of LDL particles from polyphenolic compounds that are present in the aqueous phase of serum...
  18. ncbi request reprint Recent developments concerning diet and hypertension
    L J Beilin
    University Department of Medicine, Royal Perth Hospital, University of Western Australia and HeartSearch WA, Perth, Western Australia, Australia
    Clin Exp Pharmacol Physiol 28:1078-82. 2001
    ..3. Regular coffee drinking raised blood pressure in older hypertensives, whereas potential antihypertensive effects of dietary anti-oxidants require further scrutiny...
  19. doi request reprint Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
    K S Bobridge
    School of Exercise and Health Science, Edith Cowan University, Joondalup, Western Australia, Australia
    J Hum Hypertens 27:217-24. 2013
    ..Our data suggest that gender may influence these relationships in adolescence, with significant associations observed more frequently in boys than girls...
  20. doi request reprint Associations between aggressive behaviour scores and cardiovascular risk factors in childhood
    S Louise
    Centre for Genetic Epidemiology and Biostatistics, The University of Western Australia, Crawley, Australia
    Pediatr Obes 7:319-28. 2012
    ..To examine the influence of aggressive behaviour scores on cardiovascular disease (CVD) risk factors throughout childhood...
  21. ncbi request reprint Red wine polyphenols, in the absence of alcohol, reduce lipid peroxidative stress in smoking subjects
    R Abu-Amsha Caccetta
    Department of Medicine (Royal Perth Hospital, The University of Western Australia and The West Australian Heart Research Institute, Perth, Western Australia, Australia
    Free Radic Biol Med 30:636-42. 2001
    ....
  22. ncbi request reprint Improved analysis of brachial artery ultrasound using a novel edge-detection software system
    R J Woodman
    Department of Medicine, The University of Western Australia, Perth 6001, Australia
    J Appl Physiol 91:929-37. 2001
    ..5% change in FMD. In summary, we have developed a semiautomated computerized vascular ultrasound analysis system that will improve the power of clinical intervention studies to detect small changes in arterial diameter...
  23. ncbi request reprint Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus
    G F Watts
    Department of Medicine, University of Western Australia, Royal Perth Hospital, Perth, Australia
    Diabetologia 45:420-6. 2002
    ..We assessed whether dietary supplementation with coenzyme Q(10) improves endothelial function of the brachial artery in patients with Type II (non-insulin-dependent) diabetes mellitus and dyslipidaemia...
  24. doi request reprint Dietary patterns and markers for the metabolic syndrome in Australian adolescents
    G L Ambrosini
    School of Public Health, Curtin University of Technology, Western Australia, Australia
    Nutr Metab Cardiovasc Dis 20:274-83. 2010
    ..We examined dietary patterns, CVD risk factors, and the clustering of these risk factors in 1139 14-year-olds living in Western Australia...
  25. doi request reprint Developmental programming of adult hyperinsulinemia, increased proinflammatory cytokine production, and altered skeletal muscle expression of SLC2A4 (GLUT4) and uncoupling protein 3
    Caitlin S Wyrwoll
    School of Anatomy and Human Biology, The University of Western Australia, 35 Stirling Hwy, Crawley, Perth, Western Australia 6009, Australia
    J Endocrinol 198:571-9. 2008
    ..Related changes in the skeletal muscle Slc2a4, Ucp3, and Ppard indicate that fetal glucocorticoid excess disturbs adult glucose/fatty acid transport and metabolism...
  26. doi request reprint Fish oil supplementation in early infancy modulates developing infant immune responses
    N D'Vaz
    School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia
    Clin Exp Allergy 42:1206-16. 2012
    ..Maternal fish oil supplementation during pregnancy has been associated with altered infant immune responses and a reduced risk of infant sensitization and eczema...
  27. doi request reprint Dietary glycaemic carbohydrate in relation to the metabolic syndrome in adolescents: comparison of different metabolic syndrome definitions
    T A O'Sullivan
    Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, West Perth, WA 6872, Australia
    Diabet Med 27:770-8. 2010
    ..We aimed to evaluate associations between dietary glycaemic carbohydrate and insulin resistance or the prevalence of the metabolic syndrome defined by three different criteria in a population-based adolescent cohort...
  28. ncbi request reprint Factorial study of the effects of atorvastatin and fish oil on dyslipidaemia in visceral obesity
    D C Chan
    Department of Medicine, University of Western Australia, Western Australian Institute for Medical Research, Royal Perth Hospital, Perth, Western Australia
    Eur J Clin Invest 32:429-36. 2002
    ..We investigated the effects of atorvastatin and fish oil on plasma lipid and lipoprotein levels, including remnant-like particle-cholesterol and apolipoprotein C-III, in dyslipidaemic men with visceral obesity...
  29. ncbi request reprint Associations between antioxidant status, markers of oxidative stress and immune responses in allergic adults
    J A Dunstan
    School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia
    Clin Exp Allergy 36:993-1000. 2006
    ..This study investigated the relationship between antioxidant status, markers of airways inflammation [exhaled nitric oxide (eNO)], oxidative stress (F(2) isoprostanes) and immune responses in allergic adults...
  30. ncbi request reprint Non pharmacologic therapy and lifestyle factors in hypertension
    L J Beilin
    Department of Medicine, University of Western Australia, Royal Perth Hospital, Australia
    Blood Press 10:352-65. 2001
    ....
  31. ncbi request reprint Regulatory effects of HMG CoA reductase inhibitor and fish oils on apolipoprotein B-100 kinetics in insulin-resistant obese male subjects with dyslipidemia
    Dick C Chan
    Department of Medicine, University of Western Australia and the Western Australian Institute for Medical Research, Crawley, Western Australia
    Diabetes 51:2377-86. 2002
    ..The differential effects of atorvastatin and fish oils on apoB kinetics support their combined use in correcting defective apoB metabolism in obese, insulin-resistant subjects...
  32. doi request reprint Polyunsaturated fatty acid intake and blood pressure in adolescents
    T A O'Sullivan
    Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, West Perth, Western Australia, Australia
    J Hum Hypertens 26:178-87. 2012
    ..No significant associations were observed in girls, or with the omega-6 to omega-3 ratio. Our results suggest that gender may moderate relationships between fatty acid intake and BP in adolescence...
  33. ncbi request reprint An improved method for the measurement of urinary and plasma F2-isoprostanes using gas chromatography-mass spectrometry
    T A Mori
    Department of Medicine and the Western Australian Heart Research Institute, University of Western Australia, Perth, Perth, 6000, Western
    Anal Biochem 268:117-25. 1999
    ..The inclusion of HPLC separation enables improved analysis of F2-isoprostanes by GC-MS. This methodology will assist in defining the role of F2-isoprostanes as in vivo markers of oxidant stress in clinical and experimental settings...
  34. ncbi request reprint A randomised, controlled study of the effects of aerobic exercise and dietary fish on coagulation and fibrinolytic factors in type 2 diabetics
    D W Dunstan
    Department of Medicine, University of Western Australia, West Australian Heart Research Institute, Australia
    Thromb Haemost 81:367-72. 1999
    ..Furthermore, a small, albeit significant, increase in coagulation factor VIIc associated with fish can be prevented by a concomitant programme of moderate exercise...
  35. ncbi request reprint Effects of regular ingestion of black tea on haemostasis and cell adhesion molecules in humans
    J M Hodgson
    University of Western Australia Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, Western Australia, Australia
    Eur J Clin Nutr 55:881-6. 2001
    ..To assess the effects in humans of regular ingestion of black tea on haemostasis-related variables and cell adhesion molecules...
  36. doi request reprint 20-HETE and F2-isoprostanes in the metabolic syndrome: the effect of weight reduction
    I Jung Tsai
    University of Western Australia School of Medicine and Pharmacology, Royal Perth Hospital, Perth, WA 6000, Australia
    Free Radic Biol Med 46:263-70. 2009
    ..20-HETE and oxidative stress may be important mediators of cardiovascular disease risk in the MetS. Although a 4% reduction in body weight reduced BP, there were no changes in plasma or urinary 20-HETE or F(2)-isoprostanes...
  37. doi request reprint Antioxidant defenses in the rat placenta in late gestation: increased labyrinthine expression of superoxide dismutases, glutathione peroxidase 3, and uncoupling protein 2
    Megan L Jones
    Schools of Anatomy and Human Biology, The University of Western Australia, Perth, Western Australia, Australia
    Biol Reprod 83:254-60. 2010
    ..Overall, our data suggest that the rat placenta is protected from oxidative stress by the dynamic zone- and stage-dependent expression of antioxidant defense genes...
  38. ncbi request reprint Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: a randomized, controlled trial
    Janet A Dunstan
    School of Paediatrics and Child Health, University of Western Australia, Perth, Australia
    J Allergy Clin Immunol 112:1178-84. 2003
    ..There is growing interest in the potential role of anti-inflammatory n-3 polyunsaturated fatty acids (n-3 PUFAs) in the prevention of allergic disease...
  39. ncbi request reprint Prevention of programmed hyperleptinemia and hypertension by postnatal dietary omega-3 fatty acids
    Caitlin S Wyrwoll
    School of Anatomy and Human Biology, The University of Western Australia, Nedlands, Perth, Western Australia 6009, Australia
    Endocrinology 147:599-606. 2006
    ..This raises the possibility that dietary supplementation with omega-3 fatty acids may provide a viable therapeutic option for preventing and/or reducing adverse programming outcomes in humans...
  40. ncbi request reprint Changes in cognitive measures associated with a lifestyle program for treated hypertensives: a randomized controlled trial (ADAPT)
    Valerie Burke
    School of Medicine harmacology, Royal Perth Hospital Unit and West Australian Institute for Medical Research, University of Western Australia, Perth, WA 6000, Australia
    Health Educ Res 23:202-17. 2008
    ..A cognitively based lifestyle program in treated hypertensives is associated with improvements in cognitive measures in the shorter and longer term...
  41. ncbi request reprint Similarity in the distribution of F(2)-isoprostanes in the lipid subfractions of atherosclerotic plaque and in vitro oxidised low density lipoprotein
    E I Waddington
    Department of Medicine, University of Western Australia, Royal Perth Hospital and Western Australian Institute for Medical Research, GPO Box X2213, Perth, Western Australia 6847, Australia
    Redox Rep 7:179-84. 2002
    ..The remarkably similar profiles between the oxidised LDL and advanced atherosclerotic plaque suggests oxidation in vivo, is predominantly via non-enzymatic processes directed towards the surface lipids...
  42. ncbi request reprint Oxidant stress in nephrotic syndrome: comparison of F(2)-isoprostanes and plasma antioxidant potential
    G Dogra
    Department of Medicine and Western Australian Heart Research Institute, University of Western Australia, Perth, Western Australia, Australia
    Nephrol Dial Transplant 16:1626-30. 2001
    ..Decreased total plasma antioxidant potential in combination with hyperlipidaemia may contribute to the increased risk of cardiovascular disease seen in NS...
  43. doi request reprint The Infant Fish Oil Supplementation Study (IFOS): design and research protocol of a double-blind, randomised controlled n--3 LCPUFA intervention trial in term infants
    S J Meldrum
    School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia
    Contemp Clin Trials 32:771-8. 2011
    ....
  44. ncbi request reprint Randomized controlled trial of the effect of n-3 fatty acid supplementation on the metabolism of apolipoprotein B-100 and chylomicron remnants in men with visceral obesity
    Dick C Chan
    Department of Medicine, University of Western Australia, West Australian Institute for Medical Research, Royal Perth Hospital, Perth
    Am J Clin Nutr 77:300-7. 2003
    ..Lipid abnormalities may contribute to the increased risk of atherosclerosis and coronary disease in visceral obesity. Fish oils lower plasma triacylglycerols, but the underlying mechanisms are not fully understood...
  45. ncbi request reprint Effect of atorvastatin and fish oil on plasma high-sensitivity C-reactive protein concentrations in individuals with visceral obesity
    Dick C Chan
    University Department of Medicine, University of Western Australia and the Western Australia Institute for Medical Research, Royal Perth Hospital, Perth, Western Australia WA 6847, Australia
    Clin Chem 48:877-83. 2002
    ..We studied whether dyslipidemic, obese individuals have increased plasma high-sensitivity C-reactive protein (hs-CRP) concentrations and whether treatment with atorvastatin and fish oil lowered plasma hs-CRP concentrations...
  46. ncbi request reprint Retinol supplementation in murine Plasmodium berghei malaria: effects on tissue levels, parasitaemia and lipid peroxidation
    J Hamzah
    School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia, Australia
    Int J Parasitol 37:525-37. 2007
    ..Consistent with some human malaria studies, prophylactic retinol reduces P. berghei parasitaemia. This effect relates to augmentation of tissue retinol stores rather than to retinol-associated changes in oxidant status...
  47. ncbi request reprint Effect of atorvastatin on chylomicron remnant metabolism in visceral obesity: a study employing a new stable isotope breath test
    Dick C Chan
    University Department of Medicine, Royal Perth Hospital, GPO Box X2213, Perth, Western Australia 6847, Australia
    J Lipid Res 43:706-12. 2002
    ....
  48. ncbi request reprint Urinary steroid profiles and alcohol-related blood pressure elevation
    T A Mori
    Department of Medicine, Royal Perth Hospital, Australia
    Clin Exp Pharmacol Physiol 18:287-90. 1991
    ..Such an effect is, therefore, unlikely to contribute significantly to the mechanism of alcohol-related hypertension.(ABSTRACT TRUNCATED AT 250 WORDS)..
  49. ncbi request reprint Maternal fish oil supplementation in pregnancy reduces interleukin-13 levels in cord blood of infants at high risk of atopy
    J A Dunstan
    School of Paediatrics and Child Health, University of Western Australia, Perth, Australia
    Clin Exp Allergy 33:442-8. 2003
    ..In this study we examined the effects of maternal n-3 (PUFA)-rich fish oil supplementation on cord blood (CB) IgE and cytokine levels in neonates at risk of developing allergic disease...
  50. ncbi request reprint Increased serum pigment epithelium-derived factor is associated with microvascular complications, vascular stiffness and inflammation in Type 1 diabetes
    A J Jenkins
    University of Melbourne, Department of Medicine, St Vincent s Hospital, Melbourne, Australia
    Diabet Med 24:1345-51. 2007
    ....
  51. ncbi request reprint Effects of isoflavonoids on blood pressure in subjects with high-normal ambulatory blood pressure levels: a randomized controlled trial
    J M Hodgson
    University of Western Australia Department of Medicine, Royal Perth Hospital, Australia
    Am J Hypertens 12:47-53. 1999
    ..Therefore, these results do not support the hypothesis that isoflavonoids, and genistein in particular, are major contributors to the BP lowering effect of vegetarian diets...
  52. ncbi request reprint Isoflavonoids do not inhibit in vivo lipid peroxidation in subjects with high-normal blood pressure
    J M Hodgson
    University of Western Australia Department of Medicine and the Western Australian Heart Research Institute, Royal Perth Hospital, Australia
    Atherosclerosis 145:167-72. 1999
    ..These results are not consistent with the suggestion that the two soy derived isoflavonoids have in vivo antioxidant activity at a level of intake achievable by dietary means and in subjects with high-normal BP...
  53. pmc Synergy between adiposity, insulin resistance, metabolic risk factors, and inflammation in adolescents
    Rae Chi Huang
    University of Western Australia, School of Medicine and Pharmacology, Royal Perth Hospital, Perth, Western Australia, Australia
    Diabetes Care 32:695-701. 2009
    ..The purpose of this study was to investigate relationships between inflammatory markers and components of a metabolic syndrome cluster in adolescents...
  54. ncbi request reprint Moderators and mediators of behaviour change in a lifestyle program for treated hypertensives: a randomized controlled trial (ADAPT)
    Valerie Burke
    School of Medicine harmacology, University of Western Australia, Royal Perth Hospital Unit, the Cardiovascular Research Centre and West Australian Institute for Medical Research, Perth, WA 6847, Australia
    Health Educ Res 23:583-91. 2008
    ..Mediators for physical activity in the longer term should be investigated in other models, with appropriate cognitive measurements, in future trials...
  55. doi request reprint Skim milk compared with a fruit drink acutely reduces appetite and energy intake in overweight men and women
    Emma R Dove
    School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia
    Am J Clin Nutr 90:70-5. 2009
    ..Several studies show that proteins, including whey and casein, are more satiating than carbohydrates. It follows that skim milk would be more satiating than sugar-rich beverages. However, this has yet to be shown...
  56. ncbi request reprint Maternal fish oil supplementation in pregnancy modifies neonatal leukotriene production by cord-blood-derived neutrophils
    Susan L Prescott
    School of Paediatrics and Child Health, University of Western Australia, Princess Margaret Hospital, Perth, WA 6001, Australia
    Clin Sci (Lond) 113:409-16. 2007
    ..It also provides evidence of another pathway through which long-chain PUFAs status can influence early immune development...
  57. doi request reprint Omega-3 fatty acid supplementation decreases liver fat content in polycystic ovary syndrome: a randomized controlled trial employing proton magnetic resonance spectroscopy
    Andrea J Cussons
    University of Western Australia, School of Medicine and Pharmacology, Royal Perth Hospital, Perth 6847, Western Australia
    J Clin Endocrinol Metab 94:3842-8. 2009
    ..There is an association between nonalcoholic fatty liver disease (NAFLD) and the polycystic ovary syndrome (PCOS). Marine-derived omega-3 fatty acids have favorable effects on cardiovascular risk and could reduce liver fat in NAFLD...
  58. doi request reprint Flaxseed oil supplementation increases plasma F1-phytoprostanes in healthy men
    Anne E Barden
    University of Western Australia, School of Medicine and Pharmacology, Cardiovascular Research Center, Royal Perth Hospital, 6001, Western Australia, Australia
    J Nutr 139:1890-5. 2009
    ..Future studies are needed to determine the physiological importance of increased plasma and urine F(1)-phytoprostanes and their relevance to heart disease prevention...
  59. ncbi request reprint The effects of [omega]3 fatty acids and coenzyme Q10 on blood pressure and heart rate in chronic kidney disease: a randomized controlled trial
    Trevor A Mori
    University of Western Australia and the Cardiovascular Research Centre, Perth, Western Australia
    J Hypertens 27:1863-72. 2009
    ..This study determined whether omega3FA and CoQ have independent or additive effects in improving the cardiovascular profile, particularly blood pressure and heart rate, in nondiabetic patients with CKD stages 3-4...
  60. doi request reprint Measurement of urinary F(2)-isoprostanes by gas chromatography-mass spectrometry is confounded by interfering substances
    Emilie Mas
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia and the Cardiovascular Research Center, Perth, Australia
    Free Radic Res 44:191-8. 2010
    ..These data show that care must be taken when using GC-MS for quantitation of F(2)-IsoPs to prevent interfering substances affecting the results...
  61. ncbi request reprint Regular ingestion of tea does not inhibit in vivo lipid peroxidation in humans
    Jonathan M Hodgson
    University of Western Australia, Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, WA 6001, Australia
    J Nutr 132:55-8. 2002
    ..These results do not support the suggestion that polyphenolic antioxidants derived from tea inhibit in vivo lipid peroxidation...
  62. ncbi request reprint Leukocyte count and vascular function in Type 2 diabetic subjects with treated hypertension
    Richard J Woodman
    Department of Medicine, The University of Western Australia and The West Australian Heart Research Institute, Royal Perth Hospital, Perth, Australia
    Atherosclerosis 163:175-81. 2002
    ..This study examined the associations between vascular function and markers of inflammation in Type 2 diabetic subjects with treated hypertension...
  63. doi request reprint Dietary intake and food sources of fatty acids in Australian adolescents
    Therese A O'Sullivan
    Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, West Perth, Western Australia, Australia
    Nutrition 27:153-9. 2011
    ..Our study aimed to assess fatty acid intakes in Australian adolescents, compare intakes with national guidelines, and identify major food sources of fatty acids...
  64. ncbi request reprint Acute effects of ingestion of black tea on postprandial platelet aggregation in human subjects
    Jonathan M Hodgson
    University of Western Australia Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, Australia
    Br J Nutr 87:141-5. 2002
    ..The results of this study do not support the suggestion that reduced postprandial platelet aggregability contributes to any benefits of black tea on cardiovascular risk...
  65. doi request reprint The omega-3 fatty acids EPA and DHA decrease plasma F(2)-isoprostanes: Results from two placebo-controlled interventions
    Emilie Mas
    University of Western Australia, Perth, WA, Australia
    Free Radic Res 44:983-90. 2010
    ..Neither F(3)- nor F(4)-IsoPs were observed in plasma in both studies. These results show that in humans, EPA and DHA reduce in vivo oxidant stress as measured in human plasma and urine...
  66. doi request reprint Coenzyme Q(10) and statin myalgia: what is the evidence?
    Emilie Mas
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia, Medical Research Foundation Building Level 4, Rear 50, Murray Street, Perth, WA, 6847, Australia
    Curr Atheroscler Rep 12:407-13. 2010
    ....
  67. doi request reprint Omega-3 Index correlates with healthier food consumption in adolescents and with reduced cardiovascular disease risk factors in adolescent boys
    Therese A O'Sullivan
    Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, West Perth, Australia
    Lipids 46:59-67. 2011
    ..03, P = 0.01), and diastolic blood pressure (β = -0.68, P = 0.04). The predictability of the Index for the risk of cardiovascular disease later in life warrants further investigation in the adolescent population...
  68. ncbi request reprint Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension
    Richard J Woodman
    Department of Medicine, The University of Western Australia, Perth, Australia
    Am J Clin Nutr 76:1007-15. 2002
    ..n-3 Fatty acids lower blood pressure, improve lipids, and benefit other cardiovascular disease risk factors. Effects on glycemia in patients with type 2 diabetes are uncertain...
  69. ncbi request reprint Omega-3 fatty acids and hypertension in humans
    Trevor A Mori
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia and the Cardiovascular Research Centre, Perth, Western Australia, Australia
    Clin Exp Pharmacol Physiol 33:842-6. 2006
    ..Docosahexaenoic acid may be more favourable in lowering blood pressure and heart rate, as well as improving vascular function. However, the effects of EPA and DHA may also differ depending on the target population...
  70. ncbi request reprint Lupin-enriched bread increases satiety and reduces energy intake acutely
    Ya P Lee
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Am J Clin Nutr 84:975-80. 2006
    ..Protein and fiber may be important determinants of satiety. Lupin kernel flour is a novel food ingredient that is rich in protein and fiber...
  71. ncbi request reprint n -- 3 fatty acid supplementation during pregnancy in women with allergic disease: effects on blood pressure, and maternal and fetal lipids
    Anne E Barden
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, GPO Box X2213, Perth, WA 6847, Australia
    Clin Sci (Lond) 111:289-94. 2006
    ..The effects of fish oil on lipids and blood pressure in non-pregnant individuals appear to be lost when it is administered during pregnancy...
  72. ncbi request reprint The independent effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors in humans
    Trevor A Mori
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia
    Curr Opin Clin Nutr Metab Care 9:95-104. 2006
    ..We discuss the biological effects of these fatty acids and the potential mechanisms through which they may affect cardiovascular disease risk factors...
  73. ncbi request reprint Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients
    Richard J Woodman
    Department of Medicine, Medical Research Foundation Building, The University of Western Australia, PO Box X2213, Perth, WA 6000, Australia
    Atherosclerosis 166:85-93. 2003
    ..We assessed whether purified eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from fish oil have differential effects on platelet, fibrinolytic and vascular function in patients with both conditions...
  74. ncbi request reprint A lifestyle program for treated hypertensives improved health-related behaviors and cardiovascular risk factors, a randomized controlled trial
    Valerie Burke
    University of Western Australia, School of Medicine and Pharmacology, Royal Perth Hospital Unit, the Cardiovascular Research Centre and West Australian Institute for Medical Research, Perth, Australia
    J Clin Epidemiol 60:133-41. 2007
    ..To assess effects of a cognitively based program on health-related behaviors and cardiovascular risk factors in overweight drug-treated hypertensives...
  75. ncbi request reprint Effects of a lifestyle programme on ambulatory blood pressure and drug dosage in treated hypertensive patients: a randomized controlled trial
    Valerie Burke
    University of Western Australia, School of Medicine and Pharmacology, Royal Perth Hospital Unit and West Australian Institute for Medical Research, Perth, Australia
    J Hypertens 23:1241-9. 2005
    ..To assess effects of multifactorial lifestyle modification on antihypertensive drug needs in treated hypertensive individuals...
  76. ncbi request reprint Oxidative stress in human hypertension: association with antihypertensive treatment, gender, nutrition, and lifestyle
    Natalie C Ward
    School of Medicine and Pharmacology, University of Western Australia, Western Australian Institute for Medical Research WAIMR, Perth, Australia
    Free Radic Biol Med 36:226-32. 2004
    ..The results do not support the hypothesis that treated or untreated hypertensive subjects are under increased oxidative stress compared with normotensive controls...
  77. doi request reprint Developmental programming of adult adrenal structure and steroidogenesis: effects of fetal glucocorticoid excess and postnatal dietary omega-3 fatty acids
    Brendan J Waddell
    School of Anatomy and Human Biology, The University of Western Australia, 35 Stirling Highway, Crawley, Perth, Western Australia 6009, Australia
    J Endocrinol 205:171-8. 2010
    ..In conclusion, this study shows that prenatal exposure to dexamethasone does not increase basal adrenocortical activity but does result in a more stress-responsive adrenal phenotype, possibly via increased Mc2r expression...
  78. ncbi request reprint Fish oil supplementation in pregnancy lowers F2-isoprostanes in neonates at high risk of atopy
    Anne E Barden
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, PO Box X2213, Perth, WA, 6847, Australia
    Free Radic Res 38:233-9. 2004
    ..Clinical follow-up of these infants will help to determine if there are sustained effects on postnatal oxidative stress and expression of allergic disease...
  79. ncbi request reprint An innovative program for changing health behaviours
    Valerie Burke
    Western Australian Institute for Medical Research, HeartSearch and University of Western Australia, Department of Medicine, Royal Perth Hospital, Perth, Western Australia, Australia
    Asia Pac J Clin Nutr 11:S586-97. 2002
    ..Weight loss and a decrease in waist circumference were maintained in the program group up to 16 months after entering the study. This program has the potential for wider application in other at-risk groups...
  80. ncbi request reprint Long-term follow-up of participants in a health promotion program for treated hypertensives (ADAPT)
    Valerie Burke
    University of Western Australia, School of Medicine and Pharmacology, the Cardiovascular Research Centre and West Australian Institute for Medical Research, Perth, Australia
    Nutr Metab Cardiovasc Dis 18:198-206. 2008
    ..Longer follow-up in such studies is limited; we therefore re-assessed participants after an additional 2 years in which there was no contact with program facilitators...
  81. ncbi request reprint Omega-3 fatty acids and blood pressure
    T A Mori
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia and the Cardiovascular Research Centre, Perth, Western Australia, Australia
    Cell Mol Biol (Noisy-le-grand) 56:83-92. 2010
    ....
  82. pmc Association of maternal smoking with increased infant oxidative stress at 3 months of age
    Paul S Noakes
    School of Paediatrics and Child Health, University of Western Australia, Princess Margaret Hospital for Children, Perth, WA 6840, Australia
    Thorax 62:714-7. 2007
    ..The aim of this study was to examine the effects of maternal smoking on markers of infant oxidative stress...
  83. ncbi request reprint Apolipoprotein B-100 kinetics in visceral obesity: associations with plasma apolipoprotein C-III concentration
    Dick C Chan
    Department of Medicine, University of Western Australia and the Western Australian Institute for Medical Research, Royal Perth Hospital, Perth, Australia
    Metabolism 51:1041-6. 2002
    ..Elevated plasma apoC-III concentration is also a feature of dyslipidemia in obesity that contributes to the kinetic defects in apoB metabolism...
  84. ncbi request reprint Mechanism of action of a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor on apolipoprotein B-100 kinetics in visceral obesity
    Dick C Chan
    Department of Medicine, University of Western Australia, Western Australian Institute for Medical Research, Royal Perth Hospital, Perth, Western Australia 6847
    J Clin Endocrinol Metab 87:2283-9. 2002
    ..This may be owing to up-regulation of hepatic receptors as a consequence of inhibition of cholesterogenesis...
  85. doi request reprint Dietary intake in population-based adolescents: support for a relationship between eating disorder symptoms, low fatty acid intake and depressive symptoms
    K L Allen
    Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, WA, Australia School of Psychology, The University of Western Australia, Perth, WA, Australia
    J Hum Nutr Diet 26:459-69. 2013
    ....
  86. doi request reprint Effects of lupin kernel flour-enriched bread on blood pressure: a controlled intervention study
    Ya P Lee
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Am J Clin Nutr 89:766-72. 2009
    ..Available data suggest that substitution of refined carbohydrate in the diet with protein and fiber may benefit blood pressure. Lupin kernel flour is high in protein and fiber and low in carbohydrate...
  87. pmc HDL is the major lipoprotein carrier of plasma F2-isoprostanes
    Julie M Proudfoot
    School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital, Perth WA 6847, Australia
    J Lipid Res 50:716-22. 2009
    ..Further studies are required to establish the implications of these findings on HDL function...
  88. ncbi request reprint Folic acid prevents and partially reverses glucocorticoid-induced hypertension in the rat
    Yuchun Miao
    High Blood Pressure Research Unit, John Curtin School of Medical Research, Australian National University, Canberra, Australia
    Am J Hypertens 20:304-10. 2007
    ....
  89. ncbi request reprint Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of a randomized controlled trial
    Han Yao Huang
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore 21205 2223, USA
    Am J Clin Nutr 76:549-55. 2002
    ..Evidence predominantly from in vitro studies suggests that antioxidant vitamins can prevent lipid peroxidation and that vitamin C and vitamin E have synergistic effects. However, in vivo evidence in support of these hypotheses is sparse...
  90. ncbi request reprint Induced sputum 8-isoprostane concentrations in inflammatory airway diseases
    Lisa G Wood
    Department of Respiratory and Sleep Medicine, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, NSW, 2310, Australia
    Am J Respir Crit Care Med 171:426-30. 2005
    ..Analysis of 8-iso-PGF(2alpha) concentrations in induced sputum provides a useful tool for monitoring oxidative stress and investigating strategies aimed at reducing oxidative stress in airways disease...
  91. ncbi request reprint Impact of foods enriched with n-3 long-chain polyunsaturated fatty acids on erythrocyte n-3 levels and cardiovascular risk factors
    Karen J Murphy
    Nutritional Physiology Research Centre, Division of Health Sciences, University of South Australia and School of Molecular and Biomedical Science, University of Adelaide, Adelaide, SA
    Br J Nutr 97:749-57. 2007
    ..Sustainable increases in dietary intakes and erythrocyte levels of n-3 long-chain PUFA can be achieved through regular consumption of suitably enriched processed foods. Such increases may be associated with reduced CV risk...
  92. ncbi request reprint The anti-oxidant Tempol reverses and partially prevents adrenocorticotrophic hormone-induced hypertension in the rat
    Yi Zhang
    High Blood Pressure Research Unit, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia
    J Hypertens 21:1513-8. 2003
    ..To investigate the effects of the antioxidant Tempol on prevention and reversal of adrenocorticotrophic hormone (ACTH)-induced hypertension in the rat, a model of hypertension characterized by nitric oxide deficiency...
  93. doi request reprint Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress
    Peter Hoffmann
    St Vincent s Institute of Medical Research, Fitzroy, Melbourne, Australia
    Diabetes Res Clin Pract 80:e1-3. 2008
    ..Glycated haemoglobin levels were increased in diabetes but glutathionyl haemoglobin (HbSSG) levels did not differ between groups, nor by complications; nor correlate with haemoglobin glycation or vascular risk factors...
  94. ncbi request reprint Processes involved in the site-specific effect of probucol on atherosclerosis in apolipoprotein E gene knockout mice
    Katherine Choy
    Centre for Vascular Research, University of New South Wales, Sydney, Australia
    Arterioscler Thromb Vasc Biol 25:1684-90. 2005
    ..To elucidate processes by which the antioxidant probucol increases lesion size at the aortic sinus and decreases atherosclerosis at more distal sites in apolipoprotein E-deficient (apoE(-/-)) mice...
  95. ncbi request reprint Apocynin but not allopurinol prevents and reverses adrenocorticotropic hormone-induced hypertension in the rat
    Yi Zhang
    High Blood Pressure Research Unit, John Curtin School of Medical Research, Australian National University, Australian Capital Territory, Canberra, Australia
    Am J Hypertens 18:910-6. 2005
    ..Adrenocorticotropic hormone (ACTH)-induced hypertension in the rat is accompanied by increased oxidative stress. This study examines the enzymatic source of reactive oxygen species in ACTH-hypertension...
  96. doi request reprint N-Acetylcysteine prevents but does not reverse dexamethasone-induced hypertension
    Susanne Krug
    The High Blood Pressure Research Unit, The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia
    Clin Exp Pharmacol Physiol 35:979-81. 2008
    ..N-Acetylcysteine had no effect on Dex-induced increased plasma F(2)-isoprostane concentrations. 6. In conclusion, NAC partially prevented, but did not reverse, Dex-induced hypertension...
  97. ncbi request reprint Soy food consumption does not lower LDL cholesterol in either equol or nonequol producers
    Alicia A Thorp
    Australian Technology Network Centre for Metabolic Fitness and Nutritional Physiology Research Centre, University of South Australia, South Australia, Australia
    Am J Clin Nutr 88:298-304. 2008
    ..Soy isoflavones (ISOs), particularly in individuals who produce equol, might also contribute to lipid lowering and thus reduce SP requirements...
  98. ncbi request reprint The use of novel foods enriched with long-chain n-3 fatty acids to increase dietary intake: a comparison of methodologies assessing nutrient intake
    Craig S Patch
    National Centre of Excellence in Functional Foods, University of Wollongong, New South Wales, Australia
    J Am Diet Assoc 105:1918-26. 2005
    ..To evaluate the effect of consuming a variety of foods enriched in long-chain n-3 fatty acids in low fish eaters...
  99. ncbi request reprint Antioxidant vitamins and adrenocorticotrophic hormone-induced hypertension in rats
    Christopher G Schyvens
    High Blood Pressure Research Unit, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia
    Clin Exp Hypertens 29:465-78. 2007
    ..05). AA or alpha-tocopherol failed to prevent and alpha- or gamma-tocopherol failed to reverse ACTH-induced hypertension. Thus, neither vitamin C (water soluble) nor E (lipid soluble) modified ACTH-induced hypertension in the rat...
  100. ncbi request reprint The antioxidant tempol prevents and partially reverses dexamethasone-induced hypertension in the rat
    Yi Zhang
    High Blood Pressure Research Unit, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia
    Am J Hypertens 17:260-5. 2004
    ..This study investigated the effects of Tempol, a superoxide scavenger, on prevention and reversal of hypertension induced by the synthetic glucocorticoid dexamethasone (Dex) in the rat...
  101. ncbi request reprint Induction of heme oxygenase-1 in vivo suppresses NADPH oxidase derived oxidative stress
    Srinivasa R Datla
    Bernard O Brien Institute of Microsurgery, University of Melbourne, Victoria, Australia
    Hypertension 50:636-42. 2007
    ..Thus, systemic expression of HO-1 suppresses NADPH oxidase activity by mechanisms at least partly mediated by the bile pigment bilirubin, thereby reducing oxidative stress...