T O Morgan

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. ncbi request reprint Combined renin-angiotensin system blockade and dietary sodium restriction impairs cardiomyocyte contractility
    Petcharat Trongtorsak
    Department of Medical Science, Burapha University, Chonburi, 20131, Thailand
    J Renin Angiotensin Aldosterone Syst 4:213-9. 2003
  2. ncbi request reprint Sodium, angiotensin II, blood pressure, and cardiac hypertrophy
    T O Morgan
    Department of Physiology, University of Melbourne, Parkville, Australia
    Kidney Int Suppl 67:S213-5. 1998
  3. ncbi request reprint Effect of different antihypertensive drug classes on central aortic pressure
    Trefor Morgan
    Department of Physiology, University of Melbourne, Parkville, Victoria 3010, Australia
    Am J Hypertens 17:118-23. 2004
  4. ncbi request reprint Renin, angiotensin, sodium and organ damage
    Trefor Morgan
    Department of Physiology, University of Melbourne, Victoria, Australia
    Hypertens Res 26:349-54. 2003
  5. ncbi request reprint The effect of nonsteroidal anti-inflammatory drugs on blood pressure in patients treated with different antihypertensive drugs
    Trefor Morgan
    Department of Physiology, University of Melbourne, and Hypertension Clinic, ARMC, Heidelberg, Australia
    J Clin Hypertens (Greenwich) 5:53-7. 2003
  6. ncbi request reprint Different drug classes have variable effects on blood pressure depending on the time of day
    Trefor O Morgan
    Hypertension Unit, ARMC, Heidelberg, Victoria, Australia
    Am J Hypertens 16:46-50. 2003
  7. ncbi request reprint Low doses of angiotensin converting enzyme inhibitors and angiotensin type 1 blockers have a synergistic effect but high doses are less than additive
    Trefor Morgan
    Department of Physiology, University of Melbourne, Parkville, Victoria 3010, Australia
    Am J Hypertens 15:1003-5. 2002
  8. ncbi request reprint A comparison of candesartan, felodipine, and their combination in the treatment of elderly patients with systolic hypertension
    Trefor Morgan
    Department of Physiology, University of Melbourne, Parkville, Vic, Australia
    Am J Hypertens 15:544-9. 2002
  9. ncbi request reprint Interaction of ACE inhibitors and AT(1)-receptor blockers on maximum blood pressure response in spontaneous hypertensive rats
    Trefor Morgan
    Department of Physiology, University of Melbourne, Parkville, Vic, Australia
    J Renin Angiotensin Aldosterone Syst 3:16-8. 2002
  10. ncbi request reprint Interactions between sodium and angiotensin
    T Morgan
    Department of Physiology, University of Melbourne, Parkville, Victoria, Australia
    Clin Exp Pharmacol Physiol 28:1070-3. 2001

Detail Information

Publications25

  1. ncbi request reprint Combined renin-angiotensin system blockade and dietary sodium restriction impairs cardiomyocyte contractility
    Petcharat Trongtorsak
    Department of Medical Science, Burapha University, Chonburi, 20131, Thailand
    J Renin Angiotensin Aldosterone Syst 4:213-9. 2003
    ....
  2. ncbi request reprint Sodium, angiotensin II, blood pressure, and cardiac hypertrophy
    T O Morgan
    Department of Physiology, University of Melbourne, Parkville, Australia
    Kidney Int Suppl 67:S213-5. 1998
    ..The sodium intake of the rat plays an important role influencing the cardiac but not the BP response to Ang II. These results infer that it is important to avoid episodes of acute BP elevation...
  3. ncbi request reprint Effect of different antihypertensive drug classes on central aortic pressure
    Trefor Morgan
    Department of Physiology, University of Melbourne, Parkville, Victoria 3010, Australia
    Am J Hypertens 17:118-23. 2004
    ..The clinical importance of this discrepancy needs to be evaluated...
  4. ncbi request reprint Renin, angiotensin, sodium and organ damage
    Trefor Morgan
    Department of Physiology, University of Melbourne, Victoria, Australia
    Hypertens Res 26:349-54. 2003
    ..When deciding on treatment in human hypertension these results have important clinical implications...
  5. ncbi request reprint The effect of nonsteroidal anti-inflammatory drugs on blood pressure in patients treated with different antihypertensive drugs
    Trefor Morgan
    Department of Physiology, University of Melbourne, and Hypertension Clinic, ARMC, Heidelberg, Australia
    J Clin Hypertens (Greenwich) 5:53-7. 2003
    ..If patients are on other antihypertensive agents, it is important to monitor blood pressure when a NSAID is added to therapy...
  6. ncbi request reprint Different drug classes have variable effects on blood pressure depending on the time of day
    Trefor O Morgan
    Hypertension Unit, ARMC, Heidelberg, Victoria, Australia
    Am J Hypertens 16:46-50. 2003
    ..Blood pressure (BP) is controlled by a variety of systems, the activities of which vary throughout the day. As drugs are developed that selectively block these systems, the fall in BP may not be consistent over 24 h...
  7. ncbi request reprint Low doses of angiotensin converting enzyme inhibitors and angiotensin type 1 blockers have a synergistic effect but high doses are less than additive
    Trefor Morgan
    Department of Physiology, University of Melbourne, Parkville, Victoria 3010, Australia
    Am J Hypertens 15:1003-5. 2002
    ..This study examined the effect of combination of different doses of the two drugs on blood pressure (BP)...
  8. ncbi request reprint A comparison of candesartan, felodipine, and their combination in the treatment of elderly patients with systolic hypertension
    Trefor Morgan
    Department of Physiology, University of Melbourne, Parkville, Vic, Australia
    Am J Hypertens 15:544-9. 2002
    ..The combination was well tolerated and is suitable for use in patients who do not have an adequate response to monotherapy...
  9. ncbi request reprint Interaction of ACE inhibitors and AT(1)-receptor blockers on maximum blood pressure response in spontaneous hypertensive rats
    Trefor Morgan
    Department of Physiology, University of Melbourne, Parkville, Vic, Australia
    J Renin Angiotensin Aldosterone Syst 3:16-8. 2002
    ..The combination of ACE-I and AT(1)-blocking drugs is more effective than either therapy alone and may be a useful combination to manage hypertension and/or cardiac failure...
  10. ncbi request reprint Interactions between sodium and angiotensin
    T Morgan
    Department of Physiology, University of Melbourne, Parkville, Victoria, Australia
    Clin Exp Pharmacol Physiol 28:1070-3. 2001
    ..2% NaCl intake. 5. Intake of NaCl and AngII interact at many levels. It is postulated that there is an important interaction at the cellular level that can explain the above events...
  11. ncbi request reprint ACE inhibitors, beta-blockers, calcium blockers, and diuretics for the control of systolic hypertension
    T O Morgan
    Department of Physiology, University of Melbourne, Victoria, Australia
    Am J Hypertens 14:241-7. 2001
    ..In elderly people with essential hypertension, therapy should be instituted with diuretics or calcium-blocking drugs, but combination therapy will usually be required to achieve goal...
  12. ncbi request reprint Effect of indomethacin on blood pressure in elderly people with essential hypertension well controlled on amlodipine or enalapril
    T O Morgan
    Department of Physiology, University of Melbourne, Victoria, Australia
    Am J Hypertens 13:1161-7. 2000
    ..In such patients amlodipine would appear to be a preferred choice to enalapril...
  13. ncbi request reprint Cardiac hypertrophy depends upon sleep blood pressure: a study in rats
    T O Morgan
    Department of Physiology, University of Melbourne, Parkville, Victoria, Australia
    J Hypertens 18:445-51. 2000
    ....
  14. ncbi request reprint Effects of combined administration of ACE inhibitor and angiotensin II receptor antagonist are prevented by a high NaCl intake
    C D Griffiths
    Department of Physiology, University of Melbourne, Victoria, Australia
    J Hypertens 19:2087-95. 2001
    ..The syndrome may result from depletion of angiotensinogen and the failure to synthesize sufficient angiotensin II that may be critical for normal cardiac growth and function and critical for survival...
  15. ncbi request reprint Angiotensin blocking drugs and the heart beyond 2000
    T O Morgan
    Department of Physiology, University of Melbourne, Parkville, Victoria, Australia
    J Am Soc Nephrol 10:S243-7. 1999
    ..Clinically, the AT1 receptor blocking drugs have few side effects and appear to have similar beneficial effects to angiotensin-converting enzyme inhibitors, making them suitable to treat many people with hypertension...
  16. ncbi request reprint Effects of aortic ligation on the renin angiotensin system in hydronephrotic mice
    D Y Zhang
    Department of Physiology, University of Melbourne, Parkville, Victoria, Australia
    Blood Press 8:122-7. 1999
    ..Aortic ligation results in a significant rise in blood pressure and the activity of the RAS. The mechanisms may involve a baroreceptor and/or an unknown factor...
  17. ncbi request reprint Ethanol effects on cardiomyocyte contractility
    L M Delbridge
    Department of Physiology, University of Melbourne, Parkville, Victoria 3052, Australia
    Clin Sci (Lond) 98:401-7. 2000
    ....
  18. ncbi request reprint Similar effects of treatment on central and brachial blood pressures in older hypertensive subjects in the Second Australian National Blood Pressure Trial
    Anthony M Dart
    Baker Heart Research Institute, Melbourne, Victoria 8008, Australia
    Hypertension 49:1242-7. 2007
    ..There is no evidence that the better prognosis for patients randomly assigned to ACE-I in Second Australian National Blood Pressure Trial resulted from a disproportionate lowering of central blood pressure...
  19. ncbi request reprint Brachial blood pressure but not carotid arterial waveforms predict cardiovascular events in elderly female hypertensives
    Anthony M Dart
    Baker Medical Research Institute, Melbourne, Victoria, 8008, Australia
    Hypertension 47:785-90. 2006
    ..Thus, blood pressure measurement alone is superior to measurement of arterial waveforms in predicting outcome in this group...
  20. ncbi request reprint Predictors of failure to initiate randomized treatment in a large trial of antihypertensive drug therapy in the aged
    Mark R Nelson
    Discipline of General Practice, University of Tasmania, Hobart, Australia
    Am J Hypertens 18:885-8. 2005
    ....
  21. ncbi request reprint Decreasing dietary sodium while following a self-selected potassium-rich diet reduces blood pressure
    Caryl A Nowson
    Centre for Physical Activity and Nutrition Research, School of Health Sciences, Deakin University, Burwood Highway, Burwood, VIC 2125, Australia
    J Nutr 133:4118-23. 2003
    ....
  22. ncbi request reprint A comparison of outcomes with angiotensin-converting--enzyme inhibitors and diuretics for hypertension in the elderly
    Lindon M H Wing
    School of Medicine, Flinders University, Adelaide, Australia
    N Engl J Med 348:583-92. 2003
    ..We compared the outcomes in older subjects with hypertension who were treated with angiotensin-converting-enzyme (ACE) inhibitors with the outcomes in those treated with diuretic agents...
  23. ncbi request reprint Is non-dipping status a predictor of cardiac morbidity?
    Trefor O Morgan
    J Hypertens 20:1469-71. 2002
  24. ncbi request reprint Who's really hypertensive?--Quality control issues in the assessment of blood pressure for randomized trials
    Christopher M Reid
    Department of Epidemiology and Preventive Medicine, Monash University, Melborne Australia
    Blood Press 14:133-8. 2005
    ..Repeated blood pressure measurement prior to initial diagnosis and study entry is essential to appropriately characterize hypertension in these elderly patients...
  25. doi request reprint Smaller aortic dimensions do not fully account for the greater pulse pressure in elderly female hypertensives
    Anthony M Dart
    Baker Heart Research Institute and Alfred Hospital, Melbourne, Victoria, 8008 Australia
    Hypertension 51:1129-34. 2008
    ....