P Molenaar

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. ncbi request reprint Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of Fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein
    P Molenaar
    Department of Medicine, The Prince Charles Hospital, University of Queensland, Australia
    Circulation 102:1814-21. 2000
  2. ncbi request reprint The human heart endothelin system: ET-1 synthesis, storage, release and effect
    F D Russell
    Department of Medicine, University of Queensland, The Prince Charles Hospital, Chermside, Queensland 4032, Australia
    Trends Pharmacol Sci 21:353-9. 2000
  3. pmc Cardiostimulant effects of urotensin-II in human heart in vitro
    F D Russell
    The National Heart Foundation and Prince Charles Hospital Foundation Cardiovascular Research Centre, Department of Medicine, The Prince Charles Hospital, Chermside, Queensland 4032, Australia
    Br J Pharmacol 132:5-9. 2001
  4. ncbi request reprint Human heart beta-adrenoceptors: beta1-adrenoceptor diversification through 'affinity states' and polymorphism
    P Molenaar
    Department of Medicine, The University of Queensland, The Prince Charles Hospital, Chermside, Queensland, Australia
    Clin Exp Pharmacol Physiol 34:1020-8. 2007
  5. pmc Validity of (-)-[3H]-CGP 12177A as a radioligand for the 'putative beta4-adrenoceptor' in rat atrium
    D Sarsero
    Department of Pharmacology, University of Melbourne, Parkville, Victoria, Australia
    Br J Pharmacol 123:371-80. 1998

Detail Information

Publications5

  1. ncbi request reprint Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of Fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein
    P Molenaar
    Department of Medicine, The Prince Charles Hospital, University of Queensland, Australia
    Circulation 102:1814-21. 2000
    ..We compared the effects of stimulation of beta(1)- and beta(2)-adrenergic receptors on relaxation and phosphorylation of phospholamban and troponin I in ventricle obtained from infants with tetralogy of Fallot...
  2. ncbi request reprint The human heart endothelin system: ET-1 synthesis, storage, release and effect
    F D Russell
    Department of Medicine, University of Queensland, The Prince Charles Hospital, Chermside, Queensland 4032, Australia
    Trends Pharmacol Sci 21:353-9. 2000
    ..The endothelin system might directly support the failing heart but might also contribute to its pathology, providing a basis for the therapeutic use of endothelin receptor antagonists...
  3. pmc Cardiostimulant effects of urotensin-II in human heart in vitro
    F D Russell
    The National Heart Foundation and Prince Charles Hospital Foundation Cardiovascular Research Centre, Department of Medicine, The Prince Charles Hospital, Chermside, Queensland 4032, Australia
    Br J Pharmacol 132:5-9. 2001
    ..hU-II (20 nM) increased tone (17.9% of the response to 90 mM KCI) in 7/7 tissues from 1 patient, with no response detected in 8/8 tissues from 2 patients. hU-II is a potent cardiac stimulant with low efficacy...
  4. ncbi request reprint Human heart beta-adrenoceptors: beta1-adrenoceptor diversification through 'affinity states' and polymorphism
    P Molenaar
    Department of Medicine, The University of Queensland, The Prince Charles Hospital, Chermside, Queensland, Australia
    Clin Exp Pharmacol Physiol 34:1020-8. 2007
    ..Upon segregation of patients into Arg389Gly-beta(1)-adrenoceptors, it was found that carvedilol caused a greater increase in left ventricular ejection faction in patients carrying the Arg389 allele with Arg389Arg > Arg389Gly > Gly389Gly...
  5. pmc Validity of (-)-[3H]-CGP 12177A as a radioligand for the 'putative beta4-adrenoceptor' in rat atrium
    D Sarsero
    Department of Pharmacology, University of Melbourne, Parkville, Victoria, Australia
    Br J Pharmacol 123:371-80. 1998
    ..The stereoselective interaction with the catecholamines provides further support for the classification of the receptor as 'putative beta 4-adrenoceptor'...