P B Mitchell

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi A randomized controlled trial of cognitive therapy for bipolar disorder: focus on long-term change
    Jillian R Ball
    School of Psychiatry, University of New South Wales, Randwick, New South Wales, Australia
    J Clin Psychiatry 67:277-86. 2006
  2. ncbi Transcranial magnetic stimulation for depression
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Black Dog Institute, Prince of Wales Hospital, Randwick, Australia
    Aust N Z J Psychiatry 40:406-13. 2006
  3. ncbi Emerging drugs for bipolar disorder
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Black Dog Institute, Prince of Wales Hospital, Randwick, Sydney, NSW 2031, Australia
    Expert Opin Emerg Drugs 11:621-34. 2006
  4. ncbi Bipolar disorder: the shift to overdiagnosis
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Can J Psychiatry 57:659-65. 2012
  5. ncbi Practitioner characteristics and the treatment of children and adolescents with attention deficit hyperactivity disorder
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Prince of Wales Hospital, Hospital Road, Randwick, New South Wales, Australia
    J Paediatr Child Health 48:483-9. 2012
  6. ncbi Bipolar depression: phenomenological overview and clinical characteristics
    Philip B Mitchell
    School of Psychiatry, University of New South Wales and Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Sydney, NSW, Australia
    Bipolar Disord 6:530-9. 2004
  7. ncbi Predictive and diagnostic genetic testing in psychiatry
    Philip B Mitchell
    School of Psychiatry, Prince of Wales Hospital, University of New South Wales, Randwick, Sydney, NSW 2031, Australia
    Clin Lab Med 30:829-46. 2010
  8. ncbi Diagnosis and monitoring of bipolar disorder in general practice
    Philip B Mitchell
    Black Dog Institute, Prince of Wales Hospital, and School of Psychiatry, University of New South Wales, Sydney, NSW
    Med J Aust 193:S10-3. 2010
  9. ncbi Predictive and diagnostic genetic testing in psychiatry
    Philip B Mitchell
    School of Psychiatry, Prince of Wales Hospital, University of New South Wales, Randwick, Sydney, NSW 2031, Australia
    Psychiatr Clin North Am 33:225-43. 2010
  10. ncbi Winds of change: growing demands for transparency in the relationship between doctors and the pharmaceutical industry
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, NSW
    Med J Aust 191:273-5. 2009

Collaborators

Detail Information

Publications99

  1. ncbi A randomized controlled trial of cognitive therapy for bipolar disorder: focus on long-term change
    Jillian R Ball
    School of Psychiatry, University of New South Wales, Randwick, New South Wales, Australia
    J Clin Psychiatry 67:277-86. 2006
    ..The treatment protocol differed from other published forms of CT for bipolar disorder through the addition of emotive techniques...
  2. ncbi Transcranial magnetic stimulation for depression
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Black Dog Institute, Prince of Wales Hospital, Randwick, Australia
    Aust N Z J Psychiatry 40:406-13. 2006
    ..To review the accumulated literature on the efficacy, safety and predictors of response for repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression...
  3. ncbi Emerging drugs for bipolar disorder
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Black Dog Institute, Prince of Wales Hospital, Randwick, Sydney, NSW 2031, Australia
    Expert Opin Emerg Drugs 11:621-34. 2006
    ..A number of possible future directions and challenges for the field are discussed. The treatment of bipolar disorder is unlikely to advance substantially until the causative pathogenetic molecular processes are elucidated...
  4. ncbi Bipolar disorder: the shift to overdiagnosis
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Can J Psychiatry 57:659-65. 2012
    ..We must ensure, as a profession, that any change in diagnostic practice is underpinned by rigorous and critical research inquiry...
  5. ncbi Practitioner characteristics and the treatment of children and adolescents with attention deficit hyperactivity disorder
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Prince of Wales Hospital, Hospital Road, Randwick, New South Wales, Australia
    J Paediatr Child Health 48:483-9. 2012
    ..To investigate whether recent Australian practice conforms to the draft 2009 National Health and Medical Research Council (NHMRC) guidelines on the management of attention deficit hyperactivity disorder...
  6. ncbi Bipolar depression: phenomenological overview and clinical characteristics
    Philip B Mitchell
    School of Psychiatry, University of New South Wales and Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Sydney, NSW, Australia
    Bipolar Disord 6:530-9. 2004
    ..This paper aims to review the clinical characteristics of bipolar depression, focusing upon its prevalence and phenomenology, related neuropsychological dysfunction, suicidal behaviour, disability and treatment responsiveness...
  7. ncbi Predictive and diagnostic genetic testing in psychiatry
    Philip B Mitchell
    School of Psychiatry, Prince of Wales Hospital, University of New South Wales, Randwick, Sydney, NSW 2031, Australia
    Clin Lab Med 30:829-46. 2010
    ..Finally, recommendations on the future development and availability of genetic tests in psychiatry are provided...
  8. ncbi Diagnosis and monitoring of bipolar disorder in general practice
    Philip B Mitchell
    Black Dog Institute, Prince of Wales Hospital, and School of Psychiatry, University of New South Wales, Sydney, NSW
    Med J Aust 193:S10-3. 2010
    ..Daily mood charts are useful for providing an overview of patient progress and for identifying and managing early warning signs. Families and carers can also play an active role in supporting patients with bipolar disorder...
  9. ncbi Predictive and diagnostic genetic testing in psychiatry
    Philip B Mitchell
    School of Psychiatry, Prince of Wales Hospital, University of New South Wales, Randwick, Sydney, NSW 2031, Australia
    Psychiatr Clin North Am 33:225-43. 2010
    ..Finally, recommendations on the future development and availability of genetic tests in psychiatry are provided...
  10. ncbi Winds of change: growing demands for transparency in the relationship between doctors and the pharmaceutical industry
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, NSW
    Med J Aust 191:273-5. 2009
    ..Australian universities should seriously consider developing recommendations similar to those of the AAMC...
  11. ncbi Major leads in the search for susceptibility genes for depression
    P B Mitchell
    School of Psychiatry, University of New South Wales, Prince of Wales Hospital, Randwick, Australia
    Pharmacogenomics J 3:305-7. 2003
  12. ncbi Diagnostic guidelines for bipolar depression: a probabilistic approach
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Bipolar Disord 10:144-52. 2008
    ..There are currently no accepted diagnostic criteria for bipolar depression for either research or clinical purposes. This paper aimed to develop recommendations for diagnostic criteria for bipolar I depression...
  13. ncbi Treatment of bipolar depression: focus on pharmacologic therapies
    Philip B Mitchell
    University of New South Wales, School of Psychiatry, Prince of Wales Hospital, Randwick, New South Wales 2031, Australia
    Expert Rev Neurother 5:69-78. 2005
    ..The advent of new pharmacologic and psychologic treatments provides optimism for improved outcomes for this highly disabling condition...
  14. ncbi Depression and anxiety with rimonabant
    Philip B Mitchell
    School of Psychiatry and School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    Lancet 370:1671-2. 2007
  15. ncbi Major advances in bipolar disorder
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Prince of Wales Hospital, Randwick, NSW 2031, Australia
    Med J Aust 181:207-10. 2004
    ..Comorbidity with anxiety disorders or substance misuse is common. Advances in genetics, brain imaging and basic pharmacology are starting to provide understanding of the complex causative processes...
  16. ncbi The management of bipolar disorder in general practice
    Philip B Mitchell
    School of Psychiatry, Prince of Wales Hospital, University of New South Wales, Sydney, NSW
    Med J Aust 184:566-70. 2006
    ..There has also been increasing recognition of the contribution of psychological therapies to symptom relief, relapse prevention, optimal function, and quality of life...
  17. ncbi Twelve-month prevalence and disability of DSM-IV bipolar disorder in an Australian general population survey
    P B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Psychol Med 34:777-85. 2004
    ..The authors report 12-month prevalence data for DSM-IV bipolar disorder from the Australian National Survey of Mental Health and Well-Being...
  18. ncbi Therapeutic drug monitoring of non-tricyclic antidepressant drugs
    Philip B Mitchell
    School of Psychiatry, University of New South Wales and Black Dog Institute, Sydney, Australia
    Clin Chem Lab Med 42:1212-8. 2004
    ..Potential future applications of TDM, in conjunction with genotyping of cytochrome P450 enzymes and pharmacogenomic evaluations, are discussed...
  19. ncbi Comparison of depressive episodes in bipolar disorder and in major depressive disorder within bipolar disorder pedigrees
    Philip B Mitchell
    UNSW School of Psychiatry, Prince of Wales Hospital, Randwick, Australia
    Br J Psychiatry 199:303-9. 2011
    ....
  20. ncbi Severity of stressful life events in first and subsequent episodes of depression: the relevance of depressive subtype
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Randwick and Mood Disorders Unit, Prince of Wales Hospital, Randwick NSW 2031, Australia
    J Affect Disord 73:245-52. 2003
    ..Recent studies have reignited debate concerning the relationship between stressful life events and depressive subtypes, particularly in relation to first versus subsequent episodes...
  21. ncbi Therapeutic drug monitoring of psychotropic medications
    P B Mitchell
    School of Psychiatry, University of New South Wales, Australia
    Br J Clin Pharmacol 49:303-12. 2000
    ..TDM has also been shown to be useful in avoiding toxicity (as many psychotropics have narrow therapeutic indices), particularly that due to interactions with other compounds...
  22. ncbi The place of anticonvulsants and other putative mood stabilisers in the treatment of bipolar disorder
    P B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Aust N Z J Psychiatry 33:S99-107. 1999
    ..This paper critically evaluates the current evidential basis for claims for the efficacy of these compounds in bipolar disorder...
  23. ncbi Therapeutic drug monitoring of psychotropic medications
    P B Mitchell
    School of Psychiatry, University of New South Wales, Australia
    Br J Clin Pharmacol 52:45S-54S. 2001
    ..TDM has also been shown to be useful in avoiding toxicity (as many psychotropics have narrow therapeutic indices), particularly that due to interactions with other compounds...
  24. ncbi The clinical features of bipolar depression: a comparison with matched major depressive disorder patients
    P B Mitchell
    School of Psychiatry, University of New South Wales, Australia
    J Clin Psychiatry 62:212-6; quiz 217. 2001
    ..Identification of any distinctive clinical "signatures" of bipolar depression would be helpful in determining treatment options in the clinical setting...
  25. ncbi Drug interactions of clinical significance with selective serotonin reuptake inhibitors
    P B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Drug Saf 17:390-406. 1997
    ....
  26. ncbi Psychiatry
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Sydney
    Med J Aust 176:35. 2002
  27. ncbi High levels of Gs alpha in platelets of euthymic patients with bipolar affective disorder
    P B Mitchell
    Experimental Therapeutics Branch, NIMH, Bethesda, MD, USA
    Am J Psychiatry 154:218-23. 1997
    ..To determine whether such G protein abnormalities are a trait phenomenon, the authors investigated the levels of G protein alpha subunits in platelets and lymphocytes of euthymic patients with bipolar affective disorder...
  28. ncbi Novel French antidepressants not available in the United States
    P B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Psychopharmacol Bull 31:509-19. 1995
    ..Their potential for further research or marketing in the United States is discussed...
  29. ncbi Efficacy of venlafaxine and predictors of response in a prospective open-label study of patients with treatment-resistant major depression
    P B Mitchell
    School of Psychiatry, University of New South Wales, and Prince of Wales Hospital, Sydney, Australia
    J Clin Psychopharmacol 20:483-7. 2000
    ..0005). After logistic regression, both comorbid psychiatric illness (p < 0.001) and early improvement (p < 0.0001) remained significant and independent predictors of final response...
  30. ncbi Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility allele
    I P Blair
    Neurobiology Research Program, Garvan Institute of Medical Research, Sydney, NSW, Australia
    Mol Psychiatry 11:372-83. 2006
    ..004). Together, these data provide convergent evidence that FAT and its protein partners may be components of a molecular pathway involved in susceptibility to bipolar disorder...
  31. ncbi High (15 Hz) and low (1 Hz) frequency transcranial magnetic stimulation have different acute effects on regional cerebral blood flow in depressed patients
    C K Loo
    School of Psychiatry, University of New South Wales, Australia
    Psychol Med 33:997-1006. 2003
    ..CONCLUSIONS: High (15 Hz) and low (1 Hz) frequency rTMS led to different frontal and remote relative rCBF changes, which suggests different neurophysiological and possibly neuropsychiatric consequences of a change in frequency of rTMS...
  32. ncbi Use of psychotropic medications in breast-feeding women: acute and prophylactic treatment
    M P Austin
    Department of Liaison Psychiatry, Prince of Wales Hospital, Randwick, NSW, Australia
    Aust N Z J Psychiatry 32:778-84. 1998
    ....
  33. ncbi A genome screen of 35 bipolar affective disorder pedigrees provides significant evidence for a susceptibility locus on chromosome 15q25-26
    E Z McAuley
    Neuroscience Research Program, Garvan Institute of Medical Research, Sydney, NSW, Australia
    Mol Psychiatry 14:492-500. 2009
    ....
  34. ncbi Psychotropic medications in pregnant women: treatment dilemmas
    M P Austin
    Prince of Wales Hospital, Sydney, NSW
    Med J Aust 169:428-31. 1998
    ..To review the evidence from all studies of adverse effects on infant outcome of psychotropic medications taken during pregnancy...
  35. ncbi Stylized transcript map of chromosome 4q35 encompassing the locus for a bipolar disorder susceptibility gene
    I P Blair
    Garvan Institute of Medical Research, Sydney, Australia
    Mol Psychiatry 7:669. 2002
  36. ncbi Rediscovering chronic mania
    G S Malhi
    School of Psychiatry, University of New South Wales, Sydney
    Acta Psychiatr Scand 104:153-6. 2001
    ..RESULTS: Unremitting mania poses a diagnostic and management challenge. CONCLUSION: Persistent mania of this duration is rare, but a diagnosis of chronic mania should not be rejected on the basis of chronicity...
  37. ncbi Indicators of suicide over 10 years in a specialist mood disorders unit sample
    G L Gladstone
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Clin Psychiatry 62:945-51. 2001
    ..but revealed less suicidal ideation at the time of the index MDU assessment. While these features were statistically significant, they are of limited usefulness in predicting suicide in an individual patient...
  38. ncbi Treatment-resistant depression: resistant to definition?
    G S Malhi
    Black Dog Institute, Prince of Wales Medical Research Institute, Sydney, NSW, Australia
    Acta Psychiatr Scand 112:302-9. 2005
    ..To better define treatment-resistant depression (TRD) so as to assist clinical management and refine treatment guidelines...
  39. ncbi Right versus left prefrontal transcranial magnetic stimulation for obsessive-compulsive disorder: a preliminary investigation
    P S Sachdev
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Clin Psychiatry 62:981-4. 2001
    ....
  40. ncbi Double-blind controlled investigation of bilateral prefrontal transcranial magnetic stimulation for the treatment of resistant major depression
    C K Loo
    Department of Psychiatry, Mood Disorders Unit, Black Dog Institute and Neuropsychiatric Institute, Prince of Wales Hospital, School of Psychiatry, University of New South Wales, Randwick, Australia
    Psychol Med 33:33-40. 2003
    ..There were no significant neuropsychological effects. CONCLUSIONS: Bilateral rTMS was not superior to sham in treating resistant depression in this pilot study, but caused no neuropsychological impairment...
  41. ncbi Recognizing the anxious face of depression
    Gin S Malhi
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Nerv Ment Dis 190:366-73. 2002
    ..Such a model and its definition assist in clarifying the cause of anxious depression and its treatment...
  42. ncbi Cognitive regulation of emotion in bipolar I disorder and unaffected biological relatives
    M J Green
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Acta Psychiatr Scand 124:307-16. 2011
    ..We examined the use of particular cognitive strategies for regulating negative emotion in relation to mood and temperament in BD-I, unaffected relatives of bipolar patients (UR), and healthy controls (HC)...
  43. ncbi Bipolar depression: management options
    Gin S Malhi
    School of Psychiatry, University of New South Wales, Randwick, Sydney, New South Wales, Australia
    CNS Drugs 17:9-25. 2003
    ..It therefore warrants prompt management once suitably diagnosed, especially as it is associated with a considerable risk of suicide and in the majority of instances is eminently treatable...
  44. ncbi Oxytocin enhances the encoding of positive social memories in humans
    Adam J Guastella
    Brain and Mind Research Institute, University of New South Wales, Sydney, Australia
    Biol Psychiatry 64:256-8. 2008
    ..In nonhuman mammals, oxytocin has a critical role in social recognition and the development of long-term bonds. There has been limited research evaluating effects of oxytocin on the encoding and recognition of faces in humans...
  45. ncbi The early history of convulsive therapies in Australia
    P B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, NSW
    Med J Aust 163:624-7. 1995
    ..Early response rates are discussed, as well as Australian adaptations of European techniques. Clinicians of the day considered the use of these procedures carefully and were circumspect about their future role...
  46. ncbi A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19
    R F Badenhop
    Garvan Institute of Medical Research, Sydney, Australia
    Mol Psychiatry 7:594-603. 2002
    ..In addition, several individual pedigrees gave LOD scores greater than 1.5 for previously reported bipolar susceptibility loci on chromosomes 18p11, 18q12, 22q11 and 8p22-23...
  47. ncbi Attitudes to genetic testing in families with multiple cases of bipolar disorder
    Bettina Meiser
    Psychosocial Research Group, Prince of Wales Hospital, Randwick, Australia
    Genet Test 12:233-43. 2008
    ..This study assesses interest in genetic testing for gene variations associated with bipolar disorder and associated information needs...
  48. ncbi Community attitudes towards mental health interventions for healthy people on the basis of genetic susceptibility
    Alex Wilde
    School of Psychiatry, University of New South Wales, Black Dog Institute Building, Prince of Wales Hospital, Hospital Road, Randwick, NSW 2031, Australia
    Aust N Z J Psychiatry 43:1070-6. 2009
    ..It also evaluated endorsement of genetic and environmental causal attributions of mental illness...
  49. ncbi A sham-controlled trial of the efficacy and safety of twice-daily rTMS in major depression
    Colleen K Loo
    School of Psychiatry, University of NSW and Black Dog Institute, Sydney, Australia
    Psychol Med 37:341-9. 2007
    ..Studies of repetitive transcranial magnetic stimulation (rTMS) in depression have mostly involved once-daily treatment, with positive but modest clinical results. This study tested the efficacy and safety of twice-daily rTMS over 2 weeks...
  50. ncbi Attitudes towards childbearing, causal attributions for bipolar disorder and psychological distress: a study of families with multiple cases of bipolar disorder
    Bettina Meiser
    Psychosocial Research Group, Prince of Wales Hospital, NSW, Australia
    Psychol Med 37:1601-11. 2007
    ....
  51. ncbi Repetitive transcranial magnetic stimulation for the treatment of obsessive compulsive disorder: a double-blind controlled investigation
    Perminder S Sachdev
    School of Psychiatry, University of New South Wales, Australia
    Psychol Med 37:1645-9. 2007
    ..To determine the efficacy and tolerability of repetitive transcranial magnetic stimulation (rTMS) as a treatment for obsessive compulsive disorder (OCD) in a double-blind placebo-controlled study...
  52. ncbi Characteristics of bipolar disorder in an Australian specialist outpatient clinic: comparison across large datasets
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Prince of Wales Hospital, Randwick, NSW, Australia
    Aust N Z J Psychiatry 43:109-17. 2009
    ....
  53. ncbi Does oxytocin influence the early detection of angry and happy faces?
    Adam J Guastella
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW 2050, Australia
    Psychoneuroendocrinology 34:220-5. 2009
    ..Oxytocin may have greater influence in altering the cognitive processing of social valence at more conceptual and elaborate levels of processing...
  54. ncbi Oxytocin increases gaze to the eye region of human faces
    Adam J Guastella
    School of Psychology, University of New South Wales, Kensington, Sydney, Australia
    Biol Psychiatry 63:3-5. 2008
    ..In humans, oxytocin has been found to enhance trust and the ability to interpret the emotions of others. It has been suggested that oxytocin may enhance facial processing by increasing focus on the eye region of human faces...
  55. ncbi Implications of childhood trauma for depressed women: an analysis of pathways from childhood sexual abuse to deliberate self-harm and revictimization
    Gemma L Gladstone
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Am J Psychiatry 161:1417-25. 2004
    ....
  56. ncbi Cognitive generation of affect in hypomania: an fMRI study
    Gin S Malhi
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Bipolar Disord 6:271-85. 2004
    ..To identify the brain regions associated with the cognitive generation of affect in hypomanic bipolar patients...
  57. ncbi Cognitive generation of affect in bipolar depression: an fMRI study
    Gin S Malhi
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Eur J Neurosci 19:741-54. 2004
    ..The differential patterns of activation inform us about bipolar depression and have potential diagnostic and therapeutic significance...
  58. ncbi Genome screen of 15 Australian bipolar affective disorder pedigrees supports previously identified loci for bipolar susceptibility genes
    Janice M Fullerton
    Prince of Wales Medical Research Institute, Sydney, New South Wales, Australia
    Psychiatr Genet 18:156-61. 2008
    ..The aim of this study was to identify chromosomal regions linked to BP in a new Australian extended pedigree cohort...
  59. ncbi Pharmacotherapy to limit weight gain caused by antipsychotic use
    Gin S Malhi
    The Mood Disorders Unit, The Villa, Prince of Wales Hospital, Randwick, NSW 2031, Sydney, Australia
    Expert Opin Pharmacother 4:1679-86. 2003
    ..Greater awareness and a willingness to address the problem are needed along with more research into the development of weight gain and its prevention. This review examines these issues with a pharmacotherapy focus...
  60. ncbi Making new choices about antidepressants in Australia: the long view 1975-2002
    Andrea Mant
    Quality Use of Medicines, South East Health, Sydney Hospital, PO Box 1614, Sydney, NSW 2001, Australia
    Med J Aust 181:S21-4. 2004
    ..To examine trends in types of antidepressant medications prescribed in Australia between 1975 and 2002...
  61. ncbi A review of the safety of repetitive transcranial magnetic stimulation as a clinical treatment for depression
    Colleen K Loo
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Int J Neuropsychopharmacol 11:131-47. 2008
    ..Long-term effects of repeated rTMS sessions are as yet unknown. When given within recommended guidelines, the overall safety profile of rTMS is good, and supports its further development as a clinical treatment...
  62. ncbi Implications of genetic risk information in families with a high density of bipolar disorder: an exploratory study
    Bettina Meiser
    Hereditary Cancer Clinic, Prince of Wales Hospital, Randwick, Sydney NSW 2031, Australia
    Soc Sci Med 60:109-18. 2005
    ..Results suggest that families with bipolar disorder are likely to benefit psychologically from information about the genetic basis of bipolar disorder...
  63. ncbi A Brief Measure of Worry Severity (BMWS): personality and clinical correlates of severe worriers
    Gemma L Gladstone
    School of Psychiatry, University of New South Wales and Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Randwick, NSW 2031, Australia
    J Anxiety Disord 19:877-92. 2005
    ..This study suggests that pathological worry is not only relevant for patients with GAD, but may be an equally detrimental cognitive activity for patients with panic disorder and obsessive-compulsive disorder...
  64. ncbi The expanding pharmacopoeia for bipolar disorder
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Sydney, NSW 2052, Australia
    Annu Rev Med 53:173-88. 2002
    ....
  65. ncbi A review of the efficacy of transcranial magnetic stimulation (TMS) treatment for depression, and current and future strategies to optimize efficacy
    Colleen K Loo
    School of Psychiatry, University of NSW, Psychiatrist, Black Dog Institute and South Eastern Sydney Illawarra Area Health Service, Australia
    J Affect Disord 88:255-67. 2005
    ..Factors relevant to the efficacy of rTMS are discussed along with the implications of these for the further optimization of rTMS...
  66. ncbi Community interest in predictive genetic testing for susceptibility to major depressive disorder in a large national sample
    A Wilde
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Psychol Med 41:1605-13. 2011
    ..Despite international concern about unregulated predictive genetic testing, there are surprisingly few data on both the determinants of community interest in such testing and its psychosocial impact...
  67. ncbi 'Why getting fat, Doc?' Weight gain and psychotropic medications
    G S Malhi
    Mood Disorders Unit, The Villa, Prince of Wales Hospital, Randwick, NSW, Australia
    Aust N Z J Psychiatry 35:315-21. 2001
    ..This paper aims to explore this issue and discuss the mechanisms of weight gain and methods of prevention...
  68. ncbi Issues concerning feedback about genetic testing and risk of depression
    Kay Wilhelm
    School of Psychiatry, University of New South Wales, and Black Dog Institute, Sydney, Australia
    Br J Psychiatry 194:404-10. 2009
    ..Research in genes related to risk of depression leads to the question of how this information is received by individuals...
  69. ncbi Association between the serotonin 2A receptor gene and bipolar affective disorder in an Australian cohort
    Erica Z McAuley
    Prince of Wales Medical Research Institute, University of New South Wales, Sydney, New South Wales, Australia
    Psychiatr Genet 19:244-52. 2009
    ..We assessed HTR2A for association in an Australian bipolar disorder case-control cohort...
  70. ncbi Neuropsychological deficits and functional impairment in bipolar depression, hypomania and euthymia
    Gin S Malhi
    Academic Discipline of Psychological Medicine, Northern Clinical School, University of Sydney, Sydney, NSW, Australia
    Bipolar Disord 9:114-25. 2007
    ....
  71. ncbi Lack of cortico-limbic coupling in bipolar disorder and schizophrenia during emotion regulation
    R W Morris
    School of Psychiatry, University of New South Wales, Randwick, NSW, Australia
    Transl Psychiatry 2:e90. 2012
    ....
  72. ncbi Identification, characterization, and association analysis of novel genes from the bipolar disorder susceptibility locus on chromosome 4q35
    Ian P Blair
    Garvan Institute of Medical Research, Sydney, Australia
    Psychiatr Genet 15:199-204. 2005
    ..Single nucleotide polymorphisms were identified from the candidate genes and tested for association in our case-control cohort. Our data suggest that the six candidate genes analyzed can be excluded from involvement in the disorder...
  73. ncbi Executive functioning and theory of mind in euthymic bipolar disorder
    Amanda L Olley
    School of Psychiatry, Black Dog Institute, University of New South Wales, Sydney, NSW, Australia
    Bipolar Disord 7:43-52. 2005
    ..This is consistent with other neuropsychological and neuroimaging research that points to a trait deficit in BD. Further investigation is necessary perhaps using more real-world tests...
  74. ncbi When euthymia is just not good enough: the neuropsychology of bipolar disorder
    Amanda Olley
    School of Psychiatry, University of New South Wales and Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Sydney, Australia
    J Nerv Ment Dis 193:323-30. 2005
    ....
  75. ncbi The long and the short of it: associations between 5-HTT genotypes and coping with stress
    Kay Wilhelm
    School of Psychiatry, University of New South Wales and Black Dog Institute, Sydney, Australia
    Psychosom Med 69:614-20. 2007
    ..The short (s) variant of the 5-HTT promoter polymorphism has been associated with an increased likelihood of depression after significant life stress and greater emotional reactivity to fear-invoking stimuli...
  76. ncbi Life events, first depression onset and the serotonin transporter gene
    Kay Wilhelm
    Consultation Liaison Psychiatry, Level 4, DeLacy Building, St Vincent s Hospital, Victoria Street, Sydney, New South Wales 2010, Australia
    Br J Psychiatry 188:210-5. 2006
    ..A relationship between the serotonin transporter gene, adverse events and onset of major depression has been reported...
  77. ncbi Bipolar disorder 40 years ago: a critical period of transition
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, Australia
    Aust N Z J Psychiatry 40:279-80. 2006
  78. ncbi Genetic refinement and physical mapping of a 2.3 Mb probable disease region associated with a bipolar affective disorder susceptibility locus on chromosome 4q35
    Renee F Badenhop
    Garvan Institute of Medical Research, Sydney, Australia
    Am J Med Genet B Neuropsychiatr Genet 117:23-32. 2003
    ..3 Mb. This region is very gene poor with only three known genes indicated from the YAC/BAC map. The small number of genes will facilitate systematic screening for variations associated with bipolar disorder...
  79. ncbi Public interest in predictive genetic testing, including direct-to-consumer testing, for susceptibility to major depression: preliminary findings
    Alex Wilde
    School of Psychiatry, University of New South Wales, Sydney, Black Dog Institute Building, Prince of Wales Hospital, Hospital Road, Randwick, NSW 2031, Australia
    Eur J Hum Genet 18:47-51. 2010
    ....
  80. ncbi A study using transcranial magnetic stimulation to investigate motor mechanisms in psychomotor retardation in depression
    Colleen K Loo
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Int J Neuropsychopharmacol 11:935-46. 2008
    ..Our study suggests that although the motor pathway from the motor cortex to the muscle is unimpaired, psychomotor retardation in depression is characterized by a reduced ability to drive the motor cortex...
  81. ncbi Association analysis of transcripts from the bipolar susceptibility locus on chromosome 4q35, exclusion of a pathogenic role for eight positional candidate genes
    Ian P Blair
    Garvan Institute of Medical Research, Sydney, Australia
    Am J Med Genet B Neuropsychiatr Genet 134:56-9. 2005
    ..We have therefore, excluded approximately half the genes within the chromosome 4q35 candidate interval from playing a direct pathogenic role in bipolar disorder...
  82. ncbi Techniques for the identification of genes involved in psychiatric disorders
    Ian P Blair
    School of Psychiatry, University of New South Wales and Black Dog Institute, Prince of Wales Hospital, Randwick, New South Wales 2031, Australia
    Aust N Z J Psychiatry 39:542-9. 2005
    ..Psychiatric genetics appears to be poised for significant advances in our knowledge and understanding of the molecular genetic basis of mental illness...
  83. ncbi Extended-release carbamazepine capsules: a viewpoint
    Philip B Mitchell
    School of Psychiatry, University of New South Wales, and Black Dog Institute, Prince of Wales Hospital, Sydney, New South Wales, Australia
    CNS Drugs 19:717-8. 2005
  84. ncbi Two-dimensional genome scan identifies multiple genetic interactions in bipolar affective disorder
    Janice M Fullerton
    Prince of Wales Medical Research Institute, Sydney, New South Wales 2031, Australia
    Biol Psychiatry 67:478-86. 2010
    ..Interactions between genes of small individual effect could partially explain the difficulties of traditional one-dimensional approaches to identify genetic risk factors...
  85. ncbi Altered gene expression in mice treated with the mood stabilizer sodium valproate
    Albert Chetcuti
    Neuroscience Institute of Schizophrenia and Allied Disorders (NISAD, Darlinghurst, Sydney, NSW, Australia
    Int J Neuropsychopharmacol 9:267-76. 2006
    ..Understanding the molecular and cellular mechanisms by which valproate achieves its therapeutic action represents a valuable step in clarifying the pathophysiology of bipolar disorder...
  86. ncbi The epidemiology of bipolar disorder: sociodemographic, disability and service utilization data from the Australian National Study of Low Prevalence (Psychotic) Disorders
    Vera A Morgan
    School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Perth, WA, Australia
    Bipolar Disord 7:326-37. 2005
    ..CONCLUSIONS: Despite low levels of chronicity, the burden of social disablement associated with bipolar disorder is high. The data suggest a number of important gaps in the provision of services for this predominantly treated population...
  87. ncbi Evidence into practice: the mental health hurdle is high
    Philip B Mitchell
    Med J Aust 185:295. 2006
  88. ncbi Association between antidepressant prescribing and suicide in Australia, 1991-2000: trend analysis
    Wayne D Hall
    Office of Public Policy and Ethics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia
    BMJ 326:1008. 2003
    ..If so, increased prescribing of selective serotonin reuptake inhibitors in general practice may have produced a quantifiable benefit in population mental health...
  89. ncbi Diagnostic guidelines for bipolar disorder: a summary of the International Society for Bipolar Disorders Diagnostic Guidelines Task Force Report
    S Nassir Ghaemi
    Bipolar Disorder Research Program, Department of Psychiatry, Emory University, Atlanta, GA 30322, USA
    Bipolar Disord 10:117-28. 2008
    ....
  90. ncbi Escitalopram in major depressive disorder: a multicenter, randomized, double-blind, fixed-dose, parallel trial in a Chinese population
    Pei Xian Mao
    Beijing Anding Hospital, Capital University of Medical Sciences, Beijing, China
    Depress Anxiety 25:46-54. 2008
    ..quot;..
  91. ncbi Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Arch Gen Psychiatry 60:1079-88. 2003
    ....
  92. ncbi Parental care and personality in melancholic and nonmelancholic depression
    Valerie E Whiffen
    School of Psychology, University of Ottawa, Ottawa, ON, Canada K1N 6N5
    J Nerv Ment Dis 191:358-64. 2003
    ....
  93. ncbi The Bipolar Depression Rating Scale (BDRS): its development, validation and utility
    Michael Berk
    Barwon Health and The Geelong Clinic, Geelong Department of Clinical and Biomedical Sciences, University of Melbourne and ORYGEN Research Centre, Melbourne, Victoria, Australia
    Bipolar Disord 9:571-9. 2007
    ..Both clinically and in research there is a growing need for a new observer-rated scale that is specifically designed to assess bipolar depression...
  94. ncbi The empirical redefinition of the psychometric criteria for remission in bipolar disorder
    Michael Berk
    Barwon Health and The Geelong Clinic, Geelong, Victoria, Australia
    J Affect Disord 106:153-8. 2008
    ....
  95. ncbi Gender differences in 542 Chinese inpatients with schizophrenia
    Yi lang Tang
    Beijing Anding Hospital, Capital Medical University, Beijing, PR China
    Schizophr Res 97:88-96. 2007
    ..To investigate gender differences in the onset and other clinical features of Han Chinese inpatients with schizophrenia...
  96. ncbi Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, 100 Mallett Street, Camperdown, NSW 2050, Australia
    J Affect Disord 98:137-42. 2007
    ....
  97. ncbi Gender, age, smoking behaviour and plasma clozapine concentrations in 193 Chinese inpatients with schizophrenia
    Yi lang Tang
    Beijing Anding Hospital, Capital University of Medical Sciences, Beijing, China
    Br J Clin Pharmacol 64:49-56. 2007
    ..To study the relationship between age, gender, cigarette smoking and plasma concentrations of clozapine (CLZ) and its metabolite, norclozapine (NCLZ) in Chinese patients with schizophrenia...
  98. ncbi Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder
    Ricardo Segurado
    Neuropsychiatric Genetics Unit, Department of Genetics, Trinity College, Dublin 2, Ireland
    Am J Hum Genet 73:49-62. 2003
    ..We note that meta-analysis can sometimes provide support for linkage but cannot disprove linkage in any candidate region...
  99. ncbi ECNP consensus meeting. Bipolar depression. Nice, March 2007
    Guy M Goodwin
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Eur Neuropsychopharmacol 18:535-49. 2008
    ..Assay sensitivity and patient acceptability are enhanced if the outcome in long-term studies is 'time to intervention for a new episode' for discontinuation designs...