Elizabeth A Milward

Summary

Affiliation: University of Newcastle
Country: Australia

Publications

  1. ncbi Emerging real-time technologies in molecular medicine and the evolution of integrated 'pharmacomics' approaches to personalized medicine and drug discovery
    Elizabeth A Milward
    School of Biomedical Sciences and Pharmacy and Centre for Bioinformatics, Biomarker Discovery and Information Based Medicine, The University of Newcastle, Callaghan, NSW 2308, Australia Electronic address
    Pharmacol Ther 136:295-304. 2012
  2. ncbi The matrix metalloproteinases and CNS plasticity: an overview
    E A Milward
    School of Biomedical Sciences, University of Newcastle and Hunter Medical Research Institute, Callaghan NSW 2308, Australia
    J Neuroimmunol 187:9-19. 2007
  3. ncbi A cross-sectional community study of serum iron measures and cognitive status in older adults
    Elizabeth A Milward
    The School of Biomedical Sciences, University of Newcastle, Callaghan, Australia
    J Alzheimers Dis 20:617-23. 2010
  4. ncbi Brain transcriptome perturbations in the Hfe(-/-) mouse model of genetic iron loading
    Daniel Johnstone
    School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, Australia
    Brain Res 1448:144-52. 2012
  5. ncbi Changes in brain transcripts related to Alzheimer's disease in a model of HFE hemochromatosis are not consistent with increased Alzheimer's disease risk
    Daniel M Johnstone
    School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia
    J Alzheimers Dis 30:791-803. 2012
  6. ncbi Haemochromatosis HFE gene polymorphisms as potential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age
    Zumin Shi
    Research Centre for Gender, Health and Ageing, University of Newcastle, Callaghan, Australia
    Int J Cancer 125:78-83. 2009
  7. ncbi Long-term mortality risks associated with mild anaemia in older persons: the Busselton Health Study
    Kerry A Chalmers
    School of Psychology, The University of Newcastle and Hunter Medical Research Institute, Callaghan, New South Wales, Australia
    Age Ageing 41:759-64. 2012
  8. ncbi Molecular genetic approaches to understanding the roles and regulation of iron in brain health and disease
    Daniel Johnstone
    School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, The University of Newcastle, Callaghan, New South Wales, Australia
    J Neurochem 113:1387-402. 2010
  9. ncbi Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset
    Daniel Johnstone
    Priority Research Centre for Bioinformatics, Biomarker Discovery and Information Based Medicine, The University of Newcastle, Callaghan, New South Wales, Australia
    PLoS ONE 7:e34341. 2012
  10. ncbi Noncitrus fruits as novel dietary environmental modifiers of iron stores in people with or without HFE gene mutations
    Elizabeth A Milward
    School of Biomedical Sciences and Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW, Australia
    Mayo Clin Proc 83:543-9. 2008

Collaborators

Detail Information

Publications11

  1. ncbi Emerging real-time technologies in molecular medicine and the evolution of integrated 'pharmacomics' approaches to personalized medicine and drug discovery
    Elizabeth A Milward
    School of Biomedical Sciences and Pharmacy and Centre for Bioinformatics, Biomarker Discovery and Information Based Medicine, The University of Newcastle, Callaghan, NSW 2308, Australia Electronic address
    Pharmacol Ther 136:295-304. 2012
    ..This review considers how the latest generation of advances in ultra-rapid macromolecular sequencing will accelerate the evolution of personalized medicine and more systematic, rational drug discovery...
  2. ncbi The matrix metalloproteinases and CNS plasticity: an overview
    E A Milward
    School of Biomedical Sciences, University of Newcastle and Hunter Medical Research Institute, Callaghan NSW 2308, Australia
    J Neuroimmunol 187:9-19. 2007
    ....
  3. ncbi A cross-sectional community study of serum iron measures and cognitive status in older adults
    Elizabeth A Milward
    The School of Biomedical Sciences, University of Newcastle, Callaghan, Australia
    J Alzheimers Dis 20:617-23. 2010
    ..We conclude abnormal body iron stores (low or high) are unlikely to have clinically significant effects on cognition or dementia risk in community-dwelling older people...
  4. ncbi Brain transcriptome perturbations in the Hfe(-/-) mouse model of genetic iron loading
    Daniel Johnstone
    School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, Australia
    Brain Res 1448:144-52. 2012
    ....
  5. ncbi Changes in brain transcripts related to Alzheimer's disease in a model of HFE hemochromatosis are not consistent with increased Alzheimer's disease risk
    Daniel M Johnstone
    School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia
    J Alzheimers Dis 30:791-803. 2012
    ..As Hfe-/- mice did not have higher brain iron levels than wildtype controls, these studies highlight the need for further research in models of more severe hemochromatosis with brain iron loading...
  6. ncbi Haemochromatosis HFE gene polymorphisms as potential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age
    Zumin Shi
    Research Centre for Gender, Health and Ageing, University of Newcastle, Callaghan, Australia
    Int J Cancer 125:78-83. 2009
    ..Understanding the mechanisms by which HFE interrelates with colorectal malignancies could lead to reduction of disease risk in HNPCC...
  7. ncbi Long-term mortality risks associated with mild anaemia in older persons: the Busselton Health Study
    Kerry A Chalmers
    School of Psychology, The University of Newcastle and Hunter Medical Research Institute, Callaghan, New South Wales, Australia
    Age Ageing 41:759-64. 2012
    ..The objective of this study was to examine the long-term relationships of haemoglobin concentration with all-cause and cause-specific mortality in a community-based sample of Australian adults surveyed in 1978...
  8. ncbi Molecular genetic approaches to understanding the roles and regulation of iron in brain health and disease
    Daniel Johnstone
    School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, The University of Newcastle, Callaghan, New South Wales, Australia
    J Neurochem 113:1387-402. 2010
    ....
  9. ncbi Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset
    Daniel Johnstone
    Priority Research Centre for Bioinformatics, Biomarker Discovery and Information Based Medicine, The University of Newcastle, Callaghan, New South Wales, Australia
    PLoS ONE 7:e34341. 2012
    ..We conducted independent analyses of this dataset to identify plasma protein signatures predicting pre-clinical AD...
  10. ncbi Noncitrus fruits as novel dietary environmental modifiers of iron stores in people with or without HFE gene mutations
    Elizabeth A Milward
    School of Biomedical Sciences and Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW, Australia
    Mayo Clin Proc 83:543-9. 2008
    ..To investigate whether citrus fruit, noncitrus fruit, and other dietary factors act as environmental modifiers of iron status in the absence or presence of hemochromatotic HFE gene mutations...
  11. ncbi Genome-wide microarray analysis of brain gene expression in mice on a short-term high iron diet
    Daniel Johnstone
    School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia
    Neurochem Int 56:856-63. 2010
    ..The latter involve intralysosomal lipofuscin build-up that may reflect lysosomal iron accumulation. The findings suggest that high iron intake may cause subtle brain effects of clinical relevance in some circumstances...