S Mesiano

Summary

Affiliation: University of Newcastle
Country: Australia

Publications

  1. ncbi request reprint Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium
    Sam Mesiano
    Mothers and Babies Research Center, John Hunter Hospital, Newcastle, New South Wales 2310, Australia
    J Clin Endocrinol Metab 87:2924-30. 2002
  2. ncbi request reprint Myometrial progesterone responsiveness and the control of human parturition
    Sam Mesiano
    Mothers and Babies Research Centre, University of Newcastle and John Hunter Hospital, Newcastle, New South Wales, Australia
    J Soc Gynecol Investig 11:193-202. 2004
  3. ncbi request reprint Steroid hormone control of myometrial contractility and parturition
    Sam Mesiano
    Department of Reproductive Biology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106 5034, United States
    Semin Cell Dev Biol 18:321-31. 2007
  4. ncbi request reprint Nuclear progesterone receptors in the human pregnancy myometrium: evidence that parturition involves functional progesterone withdrawal mediated by increased expression of progesterone receptor-A
    Amy A Merlino
    Department of Reproductive Biology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106 5034, USA
    J Clin Endocrinol Metab 92:1927-33. 2007
  5. ncbi request reprint Myometrial progesterone responsiveness
    Sam Mesiano
    Department of Reproductive Biology, Case Western Reserve University Department of Obstetrics Gynecology, University Hospitals Case Medical Center, Cleveland, Ohio 44106 5034, USA
    Semin Reprod Med 25:5-13. 2007
  6. ncbi request reprint Progesterone receptor or cytoskeletal protein?
    Gemma Madsen
    Mothers and Babies Research Centre, Hunter Medical Research Institute, University of Newcastle, John Hunter Hospital, Newcastle, NSW, Australia
    Reprod Sci 14:217-22. 2007
  7. ncbi request reprint Intracrine control of estrogen action in human gestational tissues at parturition
    Gemma Madsen
    Mothers and Babies Research Centre, University of Newcastle and John Hunter Hospital, Newcastle, New South Wales, Australia
    J Soc Gynecol Investig 11:213-9. 2004
  8. ncbi request reprint Prostaglandins differentially modulate progesterone receptor-A and -B expression in human myometrial cells: evidence for prostaglandin-induced functional progesterone withdrawal
    Gemma Madsen
    Mothers and Babies Research Centre, University of Newcastle and John Hunter Hospital, Newcastle, NSW, Australia
    J Clin Endocrinol Metab 89:1010-3. 2004
  9. ncbi request reprint Hormone trajectories leading to human birth
    Roger Smith
    Mothers and Babies Research Center, John Hunter Hospital, The University of Newcastle, NSW 2308, Newcastle, Australia newcstle edu au
    Regul Pept 108:159-64. 2002
  10. pmc Prostaglandin H2 synthase-1 and -2 expression in guinea pig gestational tissues during late pregnancy and parturition
    Toni Welsh
    Mothers and Babies Research Centre, Level 3 John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, NSW, 2305, Australia
    J Physiol 569:903-12. 2005

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium
    Sam Mesiano
    Mothers and Babies Research Center, John Hunter Hospital, Newcastle, New South Wales 2310, Australia
    J Clin Endocrinol Metab 87:2924-30. 2002
    ..Interaction between the PR and ER systems in the human myometrium may be critical for the control of human parturition and the coordination of progesterone withdrawal and estrogen activation required for parturition...
  2. ncbi request reprint Myometrial progesterone responsiveness and the control of human parturition
    Sam Mesiano
    Mothers and Babies Research Centre, University of Newcastle and John Hunter Hospital, Newcastle, New South Wales, Australia
    J Soc Gynecol Investig 11:193-202. 2004
    ....
  3. ncbi request reprint Steroid hormone control of myometrial contractility and parturition
    Sam Mesiano
    Department of Reproductive Biology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106 5034, United States
    Semin Cell Dev Biol 18:321-31. 2007
    ..This review addresses current understanding of how progesterone and estrogens affect the contractility of the pregnancy myometrium and how their actions are coordinated and controlled as part of the parturition cascade...
  4. ncbi request reprint Nuclear progesterone receptors in the human pregnancy myometrium: evidence that parturition involves functional progesterone withdrawal mediated by increased expression of progesterone receptor-A
    Amy A Merlino
    Department of Reproductive Biology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106 5034, USA
    J Clin Endocrinol Metab 92:1927-33. 2007
    ..We examined whether human parturition involves functional progesterone withdrawal mediated by changes in myometrial expression of progesterone receptors (PRs)-A and -B...
  5. ncbi request reprint Myometrial progesterone responsiveness
    Sam Mesiano
    Department of Reproductive Biology, Case Western Reserve University Department of Obstetrics Gynecology, University Hospitals Case Medical Center, Cleveland, Ohio 44106 5034, USA
    Semin Reprod Med 25:5-13. 2007
    ..This may be an important physiological link between the control of parturition and the immune/inflammatory process...
  6. ncbi request reprint Progesterone receptor or cytoskeletal protein?
    Gemma Madsen
    Mothers and Babies Research Centre, Hunter Medical Research Institute, University of Newcastle, John Hunter Hospital, Newcastle, NSW, Australia
    Reprod Sci 14:217-22. 2007
    ..The sc-538 nPR antibody therefore cross-reacts with cytoskeletal proteins that could be misinterpreted as nPR isoforms. Such misinterpretation has confused the progesterone response literature...
  7. ncbi request reprint Intracrine control of estrogen action in human gestational tissues at parturition
    Gemma Madsen
    Mothers and Babies Research Centre, University of Newcastle and John Hunter Hospital, Newcastle, New South Wales, Australia
    J Soc Gynecol Investig 11:213-9. 2004
    ....
  8. ncbi request reprint Prostaglandins differentially modulate progesterone receptor-A and -B expression in human myometrial cells: evidence for prostaglandin-induced functional progesterone withdrawal
    Gemma Madsen
    Mothers and Babies Research Centre, University of Newcastle and John Hunter Hospital, Newcastle, NSW, Australia
    J Clin Endocrinol Metab 89:1010-3. 2004
    ..We conclude that PGs acting via the PKC pathway facilitate functional progesterone withdrawal by increasing the myometrial PR-A/PR-B expression ratio...
  9. ncbi request reprint Hormone trajectories leading to human birth
    Roger Smith
    Mothers and Babies Research Center, John Hunter Hospital, The University of Newcastle, NSW 2308, Newcastle, Australia newcstle edu au
    Regul Pept 108:159-64. 2002
    ..Preliminary studies strongly support the hypothesis that the onset of human parturition is initiated by rising concentrations of PR-A in the myometrium...
  10. pmc Prostaglandin H2 synthase-1 and -2 expression in guinea pig gestational tissues during late pregnancy and parturition
    Toni Welsh
    Mothers and Babies Research Centre, Level 3 John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, NSW, 2305, Australia
    J Physiol 569:903-12. 2005
    ..The induction of PTGS1 in the amnion and the PYS is a critical event leading to labour in guinea pigs and models analogous changes in the human gestational tissues before labour...