Tobias Merson

Summary

Affiliation: Florey Neuroscience Institutes
Location: Melbourne, Australia
URL: www.mersonlab.org

Publications

  1. ncbi L-selectin and intercellular adhesion molecule 1 mediate lymphocyte migration to the inflamed airway/lung during an allergic inflammatory response in an animal model of asthma
    E Keramidaris
    Department of Immunology, Royal Children's Hospital, Flemington Rd, Parkville, VIC 3052, Australia
    J Allergy Clin Immunol 107:734-8. 2001
  2. ncbi Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS
    Tobias D Merson
    Florey Neuroscience Institutes, Centre for Neuroscience, University of Melbourne, Parkville, Vic, 3010, Australia
    Neuromolecular Med 12:99-132. 2010
  3. ncbi Modulation of bone morphogenic protein signalling alters numbers of astrocytes and oligodendroglia in the subventricular zone during cuprizone-induced demyelination
    Holly S Cate
    Centre for Neuroscience, University of Melbourne, Parkville, Victoria, Australia
    J Neurochem 115:11-22. 2010
  4. ncbi p75 neurotrophin receptor expression defines a population of BDNF-responsive neurogenic precursor cells
    Kaylene M Young
    Queensland Brain Institute, The University of Queensland, Brisbane QLD 4072, Australia
    J Neurosci 27:5146-55. 2007
  5. ncbi The transcriptional coactivator Querkopf controls adult neurogenesis
    Tobias D Merson
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia
    J Neurosci 26:11359-70. 2006
  6. ncbi Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination
    Ben Emery
    Department of Neurobiology, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 103:7859-64. 2006
  7. ncbi SOCS3 negatively regulates LIF signaling in neural precursor cells
    B Emery
    Multiple Sclerosis Group, The Howard Florey Institute, University of Melbourne, Melbourne, Victoria 3010, Australia
    Mol Cell Neurosci 31:739-47. 2006
  8. ncbi Development of hydrocephalus in mice lacking SOCS7
    Danielle L Krebs
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 101:15446-51. 2004
  9. ncbi Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation
    A Luchin
    Department of Molecular Genetics, Ohio State University, Columbus, Ohio 43210, USA
    J Biol Chem 276:36703-10. 2001
  10. ncbi Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome
    Chelsee A Hewitt
    The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
    PLoS ONE 5:e11561. 2010

Detail Information

Publications10

  1. ncbi L-selectin and intercellular adhesion molecule 1 mediate lymphocyte migration to the inflamed airway/lung during an allergic inflammatory response in an animal model of asthma
    E Keramidaris
    Department of Immunology, Royal Children's Hospital, Flemington Rd, Parkville, VIC 3052, Australia
    J Allergy Clin Immunol 107:734-8. 2001
    ..8% +/- 1.8%, P =.002). These findings demonstrate clear roles for both L-selectin and ICAM-1 in lymphocyte migration to the lung during an allergic inflammatory response, with ICAM-1 playing a greater role...
  2. ncbi Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS
    Tobias D Merson
    Florey Neuroscience Institutes, Centre for Neuroscience, University of Melbourne, Parkville, Vic, 3010, Australia
    Neuromolecular Med 12:99-132. 2010
    ....
  3. ncbi Modulation of bone morphogenic protein signalling alters numbers of astrocytes and oligodendroglia in the subventricular zone during cuprizone-induced demyelination
    Holly S Cate
    Centre for Neuroscience, University of Melbourne, Parkville, Victoria, Australia
    J Neurochem 115:11-22. 2010
    ..Our results suggest that lineage commitment of SVZ neural precursor cells is altered during demyelination and that BMP signalling plays a role in this process...
  4. ncbi p75 neurotrophin receptor expression defines a population of BDNF-responsive neurogenic precursor cells
    Kaylene M Young
    Queensland Brain Institute, The University of Queensland, Brisbane QLD 4072, Australia
    J Neurosci 27:5146-55. 2007
    ....
  5. ncbi The transcriptional coactivator Querkopf controls adult neurogenesis
    Tobias D Merson
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia
    J Neurosci 26:11359-70. 2006
    ..Together, our data show that Qkf is essential for normal adult neurogenesis...
  6. ncbi Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination
    Ben Emery
    Department of Neurobiology, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 103:7859-64. 2006
    ..These results indicate that modulation of SOCS3 expression could facilitate the endogenous response to CNS injury...
  7. ncbi SOCS3 negatively regulates LIF signaling in neural precursor cells
    B Emery
    Multiple Sclerosis Group, The Howard Florey Institute, University of Melbourne, Melbourne, Victoria 3010, Australia
    Mol Cell Neurosci 31:739-47. 2006
    ..However, the clonal potential of SOCS3WT/WT but not SOCS3KO/KO NPCs is enhanced by exogenous LIF. Thus, SOCS3 acts as a negative regulator of LIF signaling in NPCs...
  8. ncbi Development of hydrocephalus in mice lacking SOCS7
    Danielle L Krebs
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 101:15446-51. 2004
    ..In situ hybridization studies revealed prominent expression of Socs7 in the brain, suggestive of an important functional role of SOCS7 in this organ...
  9. ncbi Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation
    A Luchin
    Department of Molecular Genetics, Ohio State University, Columbus, Ohio 43210, USA
    J Biol Chem 276:36703-10. 2001
    ..Taken in total, the results afford an example of how lineage-specific gene regulation can be achieved by the combinatorial action of two broadly expressed transcription factors...
  10. ncbi Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome
    Chelsee A Hewitt
    The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
    PLoS ONE 5:e11561. 2010
    ..Down syndrome (DS) individuals suffer mental retardation with further cognitive decline and early onset Alzheimer's disease...