G P McNally

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi request reprint A telemetric examination of cardiovascular function during the development of, and recovery from, opiate dependence in rats
    Gavan P McNally
    School of Psychology, The University of New South Wales, Sydney, 2052, Australia
    Physiol Behav 88:55-60. 2006
  2. pmc The promises and pitfalls of retrieval-extinction procedures in preventing relapse to drug seeking
    Kate Hutton-Bedbrook
    School of Psychology, The University of New South Wales Sydney, NSW, Australia
    Front Psychiatry 4:14. 2013
  3. pmc Ventral hippocampal kappa opioid receptors mediate the renewal of fear following extinction in the rat
    Sindy Cole
    School of Psychology, The University of New South Wales, Sydney, Australia
    PLoS ONE 8:e58701. 2013
  4. doi request reprint Extinction of drug seeking: Neural circuits and approaches to augmentation
    Gavan P McNally
    The University of New South Wales, School of Psychology, Sydney, NSW 2052, Australia Electronic address
    Neuropharmacology 76:528-32. 2014
  5. ncbi request reprint Blocking, unblocking, and overexpectation of fear: a role for opioid receptors in the regulation of Pavlovian association formation
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 118:111-20. 2004
  6. ncbi request reprint Altered vulnerability to acute opiate withdrawal following stress: roles of N-methyl-D-aspartate and glucocorticoid receptors
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 119:1215-21. 2005
  7. ncbi request reprint Facilitation of fear extinction by midbrain periaqueductal gray infusions of RB101(S), an inhibitor of enkephalin-degrading enzymes
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 119:1672-7. 2005
  8. doi request reprint Placing prediction into the fear circuit
    Gavan P McNally
    School of Psychology, The University of New South Wales, Sydney, NSW, Australia
    Trends Neurosci 34:283-92. 2011
  9. ncbi request reprint A short intertrial interval facilitates acquisition of context-conditioned fear and a short retention interval facilitates its expression
    Gavan P McNally
    School of Psychology, The University of New South Wales, Sydney, Australia
    J Exp Psychol Anim Behav Process 32:164-72. 2006
  10. ncbi request reprint Opioid receptors in the midbrain periaqueductal gray regulate prediction errors during pavlovian fear conditioning
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 120:313-23. 2006

Collaborators

Detail Information

Publications44

  1. ncbi request reprint A telemetric examination of cardiovascular function during the development of, and recovery from, opiate dependence in rats
    Gavan P McNally
    School of Psychology, The University of New South Wales, Sydney, 2052, Australia
    Physiol Behav 88:55-60. 2006
    ....
  2. pmc The promises and pitfalls of retrieval-extinction procedures in preventing relapse to drug seeking
    Kate Hutton-Bedbrook
    School of Psychology, The University of New South Wales Sydney, NSW, Australia
    Front Psychiatry 4:14. 2013
    ..Moreover, under some circumstances, the retrieval - extinction procedure can significantly increase vulnerability to reinstatement in animal models...
  3. pmc Ventral hippocampal kappa opioid receptors mediate the renewal of fear following extinction in the rat
    Sindy Cole
    School of Psychology, The University of New South Wales, Sydney, Australia
    PLoS ONE 8:e58701. 2013
    ..These findings show that hippocampal KORs are involved in fear renewal and also identify a dissociation in the contribution of VH and DH KORs to the expression of renewed fear...
  4. doi request reprint Extinction of drug seeking: Neural circuits and approaches to augmentation
    Gavan P McNally
    The University of New South Wales, School of Psychology, Sydney, NSW 2052, Australia Electronic address
    Neuropharmacology 76:528-32. 2014
    ..They hold promise as novel strategies to promote abstinence from drug seeking. This article is part of a Special Issue entitled 'NIDA 40th Anniversary Issue'...
  5. ncbi request reprint Blocking, unblocking, and overexpectation of fear: a role for opioid receptors in the regulation of Pavlovian association formation
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 118:111-20. 2004
    ..These results are consistent with a role for opioid receptors controlling Pavlovian association formation by regulating the discrepancy (lambda - SigmaV) described by R. A. Rescorla and A. R. Wagner (1972)...
  6. ncbi request reprint Altered vulnerability to acute opiate withdrawal following stress: roles of N-methyl-D-aspartate and glucocorticoid receptors
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 119:1215-21. 2005
    ..Together these experiments show that restraint stress alters vulnerability to opiate withdrawal and identify activation of NMDA and glucocorticoid receptors as causal to this vulnerability...
  7. ncbi request reprint Facilitation of fear extinction by midbrain periaqueductal gray infusions of RB101(S), an inhibitor of enkephalin-degrading enzymes
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 119:1672-7. 2005
    ..These results confirm that vIPAG endogenous opioids contribute to fear extinction and show that extinction can be facilitated by manipulations that increase vIPAG opioid neuromodulation...
  8. doi request reprint Placing prediction into the fear circuit
    Gavan P McNally
    School of Psychology, The University of New South Wales, Sydney, NSW, Australia
    Trends Neurosci 34:283-92. 2011
    ..This aversive prediction error circuit might represent a conserved mechanism for regulating fear learning in mammals...
  9. ncbi request reprint A short intertrial interval facilitates acquisition of context-conditioned fear and a short retention interval facilitates its expression
    Gavan P McNally
    School of Psychology, The University of New South Wales, Sydney, Australia
    J Exp Psychol Anim Behav Process 32:164-72. 2006
    ..The effects of the training to test interval on performance are predicted by Wagner's sometimes opponent process (SOP) theory (Wagner, 1981)...
  10. ncbi request reprint Opioid receptors in the midbrain periaqueductal gray regulate prediction errors during pavlovian fear conditioning
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 120:313-23. 2006
    ..These experiments show that v1PAG micro-opioid receptors contribute to Pavlovian fear learning by regulating predictive error...
  11. ncbi request reprint Predicting danger: the nature, consequences, and neural mechanisms of predictive fear learning
    Gavan P McNally
    School of Psychology, The University of New South Wales, Sydney 2052, Australia
    Learn Mem 13:245-53. 2006
    ..Finally, it reviews recent data from rodent and human studies that have begun to identify the neural mechanisms for direct and indirect predictive fear learning...
  12. ncbi request reprint The midbrain periaqueductal gray and fear extinction: opioid receptor subtype and roles of cyclic AMP, protein kinase A, and mitogen-activated protein kinase
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 119:1023-33. 2005
    ..These mechanisms are different from the cellular mechanisms for extinction in the amygdala and from the known cellular mechanisms for opioid analgesia in the vlPAG...
  13. ncbi request reprint Opioid receptors in the midbrain periaqueductal gray regulate extinction of pavlovian fear conditioning
    Gavan P McNally
    School of Psychology, The University of New South Wales, Sydney, New South Wales 2052, Australia
    J Neurosci 24:6912-9. 2004
    ..During nonreinforcement, this vlPAG opioid receptor contribution signals extinction...
  14. ncbi request reprint A peripheral, intracerebral, or intrathecal administration of an opioid receptor antagonist blocks illness-induced hyperalgesia in the rat
    G P McNally
    School of Psychology, University of New South Wales, Sydney, Australia
    Behav Neurosci 114:1183-90. 2000
    ..These results document a pain facilitatory role of opioid receptors in both the peripheral and central nervous systems and are discussed with reference to their analgesic and motivational functions...
  15. ncbi request reprint Effects of contextual or olfactory cues previously paired with morphine withdrawal on behavior and pain sensitivity in the rat
    G P McNally
    Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Psychopharmacology (Berl) 156:381-7. 2001
    ..At least one locus for this contribution is during opiate withdrawal. These experiments studied the contribution of Pavlovian conditioning processes to morphine withdrawal...
  16. ncbi request reprint Role of corticotropin-releasing hormone in the amygdala and bed nucleus of the stria terminalis in the behavioral, pain modulatory, and endocrine consequences of opiate withdrawal
    G P McNally
    Mental Health Research Institute, The University of Michigan, Ann Arbor, MI, USA
    Neuroscience 112:605-17. 2002
    ....
  17. ncbi request reprint Temporally graded, context-specific retrograde amnesia and its alleviation by context preexposure: effects of postconditioning exposures to morphine in the rat
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, New South Wales 2052, Australia
    J Exp Psychol Anim Behav Process 29:130-42. 2003
    ..These results show that retrograde deficits in contextual fear conditioning are mediated by failures to consolidate a contextual representation...
  18. pmc GABA(A) receptors determine the temporal dynamics of memory retention
    Gavan P McNally
    School of Psychology, The University of New South Wales, Sydney 2052, Australia
    Learn Mem 15:106-11. 2008
    ..Our results suggest that the temporal dynamics of memory retention may be caused by variations in neurotransmission through the GABA(A) receptor in the post-training period...
  19. ncbi request reprint Anterograde amnesia for Pavlovian fear conditioning and the role of one-trial overshadowing: effects of preconditioning exposures to morphine in the rat
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, New South Wales 2052, Australia
    J Exp Psychol Anim Behav Process 29:222-32. 2003
    ..These results suggest that anterograde deficits in Pavlovian fear conditioning emerged from differences in susceptibility to 1-trial overshadowing of context by CS...
  20. ncbi request reprint Selective down-regulation of hippocampal glucocorticoid receptors during opiate withdrawal
    Gavan P McNally
    Mental Health Research Institute, The University of Michigan, USA
    Brain Res Mol Brain Res 118:152-5. 2003
    ....
  21. ncbi request reprint Opioid receptors regulate the extinction of Pavlovian fear conditioning
    Gavan P McNally
    School of Psychology, University of New South Wales, Sydney, New South Wales, Australia
    Behav Neurosci 117:1292-301. 2003
    ..These experiments show that opioid receptors regulate the development, but not the expression, of fear extinction and are discussed with reference to the roles of opioid receptors in US processing, memory, and appetitive motivation...
  22. ncbi request reprint Acute exposure to saccharin reduces morphine analgesia in the the rat: evidence for involvement of N-methyl-D-aspartate and peripheral opioid receptors
    G P McNally
    School of Psychology, The University of New South Wales, Australia
    Psychopharmacology (Berl) 149:56-62. 2000
    ..Exposure to a sweet taste also reduces morphine analgesia. We studied whether this taste-mediated reduction was reversed by an NMDA or peripheral opioid receptor antagonist...
  23. doi request reprint Renewal of extinguished cocaine-seeking
    A S Hamlin
    School of Psychology, The University of New South Wales, Sydney, New South Wales, 2052, Australia
    Neuroscience 151:659-70. 2008
    ....
  24. ncbi request reprint The neural correlates and role of D1 dopamine receptors in renewal of extinguished alcohol-seeking
    A S Hamlin
    School of Psychology, The University of New South Wales, Sydney, NSW, 2052, Australia
    Neuroscience 146:525-36. 2007
    ..Neuroscience 143:25-38] permits identification of similarities and differences in the correlates of renewal of extinguished drug- and natural-reward seeking...
  25. pmc Opioid receptors mediate direct predictive fear learning: evidence from one-trial blocking
    Sindy Cole
    School of Psychology, The University of New South Wales, Sydney 2052, Australia
    Learn Mem 14:229-35. 2007
    ..These results show that opioid receptors mediate the direct actions of predictive error on Pavlovian association formation...
  26. ncbi request reprint Increased vulnerability to stress following opiate exposures: behavioral and autonomic correlates
    Kate E Blatchford
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 119:1034-41. 2005
    ..The results show that a history of opiate exposures alters vulnerability to stress and has implications for understanding coping, anxiety, and emotionality in former opiate users...
  27. ncbi request reprint Temporal-difference prediction errors and Pavlovian fear conditioning: role of NMDA and opioid receptors
    Sindy Cole
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 121:1043-52. 2007
    ..They suggest that NMDA receptors contribute to fear learning by acting on the product of predictive error, whereas opioid receptors contribute to predictive error...
  28. doi request reprint US habituation, like CS extinction, produces a decrement in conditioned fear responding that is NMDA dependent and subject to renewal and reinstatement
    Andreas Berg Storsve
    School of Psychology, The University of New South Wales, Sydney 2052, Australia
    Neurobiol Learn Mem 93:463-71. 2010
    ..Together, these results suggest that the decrement in conditioned fear responses produced by US habituation and CS extinction could rely on overlapping processes...
  29. doi request reprint Conditioned stimulus familiarity determines effects of MK-801 on fear extinction
    Wan Yee Macy Chan
    School of Psychology, University of New South Wales, Sydney, Australia
    Behav Neurosci 123:303-14. 2009
    ..These experiments show that CS familiarity is an important determinant of effects of MK-801 on fear extinction learning: MK-801 impaired extinction learning about novel stimuli but spared extinction learning about familiar stimuli...
  30. doi request reprint Complementary roles for amygdala and periaqueductal gray in temporal-difference fear learning
    Sindy Cole
    School of Psychology, The University of New South Wales, Sydney 2052, Australia
    Learn Mem 16:1-7. 2009
    ..These findings identify complementary but dissociable roles for amygdala NMDA receptors and vlPAG MOR in temporal-difference predictive fear learning...
  31. doi request reprint Unblocking in Pavlovian fear conditioning
    Laura Bradfield
    School of Psychology, University of New South Wales, Sydney, Australia
    J Exp Psychol Anim Behav Process 34:256-65. 2008
    ..The results show that variations in US intensity or number produce unblocking of fear learning, but for each there is a different profile of associative change and a potentially different mechanism...
  32. ncbi request reprint Opioid receptors in the nucleus accumbens regulate attentional learning in the blocking paradigm
    Mihaela D Iordanova
    School of Psychology, The University of New South Wales, Sydney, New South Wales 2052, Australia
    J Neurosci 26:4036-45. 2006
    ....
  33. doi request reprint The effects of FG7142 on overexpectation of Pavlovian fear conditioning
    Joshua B B Garfield
    School of Psychology, The University of New South Wales, Sydney, Australia
    Behav Neurosci 123:75-85. 2009
    ..They support claims that overexpectation shares features with extinction...
  34. ncbi request reprint Pain facilitatory circuits in the mammalian central nervous system: their behavioral significance and role in morphine analgesic tolerance
    G P McNally
    Mental Health Research Institute, University of Michigan, Ann Arbor 48109 0720, USA
    Neurosci Biobehav Rev 23:1059-78. 1999
    ....
  35. ncbi request reprint Effects of an odor paired with illness on startle, freezing, and analgesia in rats
    Rick Richardson
    School of Psychology, University of New South Wales, Sydney NSW 2052, Australia
    Physiol Behav 78:213-9. 2003
    ..potential threshold differences for various expressions of learned fear and (2). the possibility that the content of the learning established by odor-shock pairings differ from those established by odor-illness pairings...
  36. doi request reprint The role of nucleus accumbens shell in learning about neutral versus excitatory stimuli during Pavlovian fear conditioning
    Laura A Bradfield
    School of Psychology, The University of New South Wales, Sydney 2052, Australia
    Learn Mem 17:337-43. 2010
    ..AcbSh is required to reduce the processing of established predictors, thereby permitting neutral or less predictive stimuli to be learned about...
  37. ncbi request reprint The effects of FG7142 on two types of forgetting in 18-day-old rats
    Helen H Y Tang
    School of Psychology, University of New South Wales, Sydney, Australia
    Behav Neurosci 121:1421-5. 2007
    ..These results suggest that in the developing rat, forgetting observed at different retention intervals is mediated by different physiological mechanisms...
  38. ncbi request reprint Recovery of fear memories in rats: role of gamma-amino butyric acid (GABA) in infantile amnesia
    Jee Hyun Kim
    School of PsychologyUniversity of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 120:40-8. 2006
    ..It appears that GABA may be involved in infantile amnesia regardless of the emotional content of the memory...
  39. ncbi request reprint Induction of Fos proteins in regions of the nucleus accumbens and ventrolateral striatum correlates with catalepsy and stereotypic behaviours induced by morphine
    Adam S Hamlin
    Pain Management Research Institute, The University of Sydney, Royal North Shore Hospital, St Leonards, NSW 2065, Sydney, Australia
    Neuropharmacology 56:798-807. 2009
    ..These data provide further confirmation that psychomotor sensitisation induced by repetitive morphine exposure involves long-term neuroadaptations in basal ganglia circuitry particularly at the level of the nucleus accumbens...
  40. ncbi request reprint Altered responsivity to central administrations of corticotropin-releasing factor in rats with a history of opiate exposures
    Kate E Blatchford
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    Behav Neurosci 120:1169-74. 2006
    ..5-microg CRF 1 or 7 days after last opiate exposure. These findings suggest that alterations in central CRF circuits may underpin the increased vulnerability to anxiety observed following opiate exposures...
  41. ncbi request reprint Renewal of an extinguished instrumental response: neural correlates and the role of D1 dopamine receptors
    A S Hamlin
    School of Psychology, The University of New South Wales, Sydney, New South Wales, 2052, Australia
    Neuroscience 143:25-38. 2006
    ..D1 dopamine receptors within this circuit are essential for renewal. The results also suggest that rostral agranular insular cortex may play an important role in suppressing reward-seeking after extinction training...
  42. ncbi request reprint Paraventricular thalamus mediates context-induced reinstatement (renewal) of extinguished reward seeking
    Adam S Hamlin
    School of Psychology, The University of New South Wales, Sydney, NSW, Australia
    Eur J Neurosci 29:802-12. 2009
    ..These lesions had no effect on the acquisition of reward seeking. These results show that PvTh mediates context-induced reinstatement and that this renewal is associated with recruitment of a PvTh-AcbSh pathway...
  43. ncbi request reprint Cocaine and amphetamine related transcript (CART) inhibits context induced reinstatement of reward seeking
    Bradley J King
    School of Psychology, The University of New South Wales, Sydney, NSW, 2052, Australia
    Behav Neurosci 124:423-7. 2010
    ..ICV CART55-102 also altered the profile of behavioral responses observed on test in the training (ABA) but not extinction (ABB) context. These results identify a novel role for CART in preventing reinstatement of reward seeking...
  44. ncbi request reprint Induction of c-Fos and zif268 in the nociceptive amygdala parallel abstinence hyperalgesia in rats briefly exposed to morphine
    Adam S Hamlin
    Pain Management Research Institute Kolling Institute, The University of Sydney at the Royal North Shore Hospital, St Leonards, NSW 2065, Australia
    Neuropharmacology 53:330-43. 2007
    ....