S V McLennan


Affiliation: University of Sydney
Country: Australia


  1. request reprint
    McLennan S, Wang X, Moreno V, Yue D, Twigg S. Connective tissue growth factor mediates high glucose effects on matrix degradation through tissue inhibitor of matrix metalloproteinase type 1: implications for diabetic nephropathy. Endocrinology. 2004;145:5646-55 pubmed
  2. request reprint
    McLennan S, Kelly D, Schache M, Waltham M, Dy V, Langham R, et al. Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?. Kidney Int. 2007;72:481-8 pubmed
    ..Our findings suggest that diminished expression of the glycoprotein-degrading enzyme, MMP-7, may play a role in fibronectin accumulation in the diabetic kidney in response to AGEs and/or TGF-beta. ..