Robert A McLaughlin

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi request reprint Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley, WA 6009, Australia
    Opt Express 16:17521-9. 2008
  2. doi request reprint Parametric imaging of cancer with optical coherence tomography
    Robert A McLaughlin
    University of Western Australia, School of Electrical, Electronic and Computer Engineering, Crawley, West Australia, Australia
    J Biomed Opt 15:046029. 2010
  3. ncbi request reprint Mapping tissue optical attenuation to identify cancer using optical coherence tomography
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, Uni Western Australia, WA, Australia
    Med Image Comput Comput Assist Interv 12:657-64. 2009
  4. doi request reprint Imaging of human lymph nodes using optical coherence tomography: potential for staging cancer
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic, and Computer Engineering, M018, University of Western Australia, Crawley, Western Australia, Australia
    Cancer Res 70:2579-84. 2010
  5. ncbi request reprint Respiratory gating of anatomical optical coherence tomography images of the human airway
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley WA 6009, Australia
    Opt Express 17:6568-77. 2009
  6. pmc Distribution of airway narrowing responses across generations and at branching points, assessed in vitro by anatomical optical coherence tomography
    Peter B Noble
    Division of Clinical Sciences, Telethon Institute for Child Health Research, Roberts Road, Perth, 6008, Australia
    Respir Res 11:9. 2010
  7. doi request reprint Dual-modality needle probe for combined fluorescence imaging and three-dimensional optical coherence tomography
    Dirk Lorenser
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, WA, Australia
    Opt Lett 38:266-8. 2013
  8. doi request reprint Static and dynamic imaging of alveoli using optical coherence tomography needle probes
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley, Western Australia, Australia
    J Appl Physiol 113:967-74. 2012
  9. doi request reprint High-sensitivity anastigmatic imaging needle for optical coherence tomography
    Loretta Scolaro
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, Crawley, WA 6009, Australia
    Opt Lett 37:5247-9. 2012
  10. doi request reprint Using optical coherence tomography to improve diagnostic and therapeutic bronchoscopy
    Jonathan P Williamson
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Perth, WA 6009, Australia
    Chest 136:272-6. 2009

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley, WA 6009, Australia
    Opt Express 16:17521-9. 2008
    ..The paper also illustrates the capability of the system to assess the real-time dynamic changes within the airway that occur during respiration...
  2. doi request reprint Parametric imaging of cancer with optical coherence tomography
    Robert A McLaughlin
    University of Western Australia, School of Electrical, Electronic and Computer Engineering, Crawley, West Australia, Australia
    J Biomed Opt 15:046029. 2010
    ..We present the first parametric OCT images of human lymph nodes containing malignant cells, and demonstrate improved tissue contrast over en face OCT images...
  3. ncbi request reprint Mapping tissue optical attenuation to identify cancer using optical coherence tomography
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, Uni Western Australia, WA, Australia
    Med Image Comput Comput Assist Interv 12:657-64. 2009
    ..The algorithm is applied to ex vivo samples of human axillary lymph nodes and validated against a histological gold standard. Results are shown illustrating the variation in optical properties between cancerous and healthy tissue...
  4. doi request reprint Imaging of human lymph nodes using optical coherence tomography: potential for staging cancer
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic, and Computer Engineering, M018, University of Western Australia, Crawley, Western Australia, Australia
    Cancer Res 70:2579-84. 2010
    ....
  5. ncbi request reprint Respiratory gating of anatomical optical coherence tomography images of the human airway
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley WA 6009, Australia
    Opt Express 17:6568-77. 2009
    ..It is shown that respiratory gating can substantially improve the quality of aOCT images and reveal events and features that are otherwise obscured by blurring...
  6. pmc Distribution of airway narrowing responses across generations and at branching points, assessed in vitro by anatomical optical coherence tomography
    Peter B Noble
    Division of Clinical Sciences, Telethon Institute for Child Health Research, Roberts Road, Perth, 6008, Australia
    Respir Res 11:9. 2010
    ..Whilst heterogeneity has been detected by previous experimental approaches, its spatial relationship either within or between airways is unknown...
  7. doi request reprint Dual-modality needle probe for combined fluorescence imaging and three-dimensional optical coherence tomography
    Dirk Lorenser
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, WA, Australia
    Opt Lett 38:266-8. 2013
    ..We were able to identify alveoli, bronchioles, and blood vessels. The results demonstrate that the combined OCT plus fluorescence needle images provide improved tissue differentiation over OCT alone...
  8. doi request reprint Static and dynamic imaging of alveoli using optical coherence tomography needle probes
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley, Western Australia, Australia
    J Appl Physiol 113:967-74. 2012
    ..We also present the first dynamic OCT images acquired with an OCT needle probe, allowing tracking of individual alveoli during simulated cyclical lung inflation and deflation...
  9. doi request reprint High-sensitivity anastigmatic imaging needle for optical coherence tomography
    Loretta Scolaro
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, Crawley, WA 6009, Australia
    Opt Lett 37:5247-9. 2012
    ..Our needle achieves the highest sensitivity of currently reported OCT imaging needles (112 dB), and we demonstrate its performance by superficial imaging of human skin and 3D volumetric imaging within a biological sample...
  10. doi request reprint Using optical coherence tomography to improve diagnostic and therapeutic bronchoscopy
    Jonathan P Williamson
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Perth, WA 6009, Australia
    Chest 136:272-6. 2009
    ..The severity of newly diagnosed tracheomalacia was able to be quantified using aOCT imaging (subject 3). aOCT imaging during bronchoscopy allows accurate real-time airway measurements and may assist bronchoscopic assessment...
  11. ncbi request reprint Feasibility of Applying Real-time Optical Imaging During Bronchoscopic Interventions for Central Airway Obstruction
    Jonathan P Williamson
    Departments of Pulmonary Physiology Respiratory Medicine Radiology, Sir Charles Gairdner Hospital School of Anatomy and Human Biology Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia West Australian Sleep Disorders Research Institute, Perth, Australia
    J Bronchology Interv Pulmonol 17:307-16. 2010
    ..This study aims to describe the potential role of real-time aOCT in guiding interventions during CAO procedures...
  12. ncbi request reprint Ultrasound-guided optical coherence tomography needle probe for the assessment of breast cancer tumor margins
    Andrea Curatolo
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009, Australia
    AJR Am J Roentgenol 199:W520-2. 2012
    ..The technique entails deployment of a high-resolution optical imaging needle under ultrasound guidance. Assessment was performed on fresh ex vivo tissue samples...
  13. doi request reprint In vivo assessment of human burn scars through automated quantification of vascularity using optical coherence tomography
    Yih Miin Liew
    The University of Western Australia, School of Electrical, Electronic and Computer Engineering, Optical and Biomedical Engineering Laboratory, Crawley, Perth, Australia
    J Biomed Opt 18:061213. 2013
    ..This study establishes the feasibility of this methodology as a means of clinical monitoring of scar progression...
  14. doi request reprint In situ imaging of lung alveoli with an optical coherence tomography needle probe
    Bryden C Quirk
    University of Western Australia, School of Electrical, Electronic and Computer Engineering, Crawley, WA 6009, Australia
    J Biomed Opt 16:036009. 2011
    ..We present the first published images of alveoli acquired with an OCT needle probe and demonstrate the potential of this technique to visualize other anatomical features such as bifurcations of the bronchioles...
  15. doi request reprint In vivo dynamic optical coherence elastography using a ring actuator
    Brendan F Kennedy
    School of Electrical, Electronic and Computer Engineering, The University of Western Australia, Crawley, Western Australia, Australia
    Opt Express 17:21762-72. 2009
    ..The results constitute the first demonstration of a practical means of performing in vivo dynamic optical coherence elastography on a human subject...
  16. doi request reprint En face parametric imaging of tissue birefringence using polarization-sensitive optical coherence tomography
    Lixin Chin
    The University of Western Australia, School of Electrical, Electronic and Computer Engineering, Optical Biomedical Engineering Laboratory, Crawley, Western Australia 6009, Australia
    J Biomed Opt 18:066005. 2013
    ..The resulting en face images of tissue birefringence are more useful than conventional PS-OCT B-scans in assessing the severity of tissue damage and in localizing the spatial extent of damage...
  17. doi request reprint Reduction of image artifacts in three-dimensional optical coherence tomography of skin in vivo
    Yih Miin Liew
    The University of Western Australia, School of Electrical, Electronic and Computer Engineering, Crawley, WA 6009, Australia
    J Biomed Opt 16:116018. 2011
    ..Based on our findings, recommendations are given for optimal OCT imaging of skin in vivo...
  18. doi request reprint Imaging true 3D endoscopic anatomy by incorporating magnetic tracking with optical coherence tomography: proof-of-principle for airways
    Brandon Lau
    School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley, WA, Australia
    Opt Express 18:27173-80. 2010
    ..We characterize the accuracy of the system, and present the first published magnetic tracker-assisted endoscopic OCT reconstructions using a phantom airway...
  19. doi request reprint Needle optical coherence elastography for tissue boundary detection
    Kelsey M Kennedy
    Optical Biomedical Engineering Laboratory, The University of Western Australia, WA 6009, Australia
    Opt Lett 37:2310-2. 2012
    ..Results demonstrate differentiation of tissues based on mechanical properties and highlight the potential of needle OCE for in vivo tissue boundary detection...