Research Topics
Species | John McGrathSummaryAffiliation: University of Queensland Country: Australia Publications
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Publications
The surprisingly rich contours of schizophrenia epidemiologyJohn J McGrath
Queensland Centre for Mental Health Research, University of Queensland, Wacol, QLD 4076, Australia
Arch Gen Psychiatry 64:14-6. 2007
Decanalization, brain development and risk of schizophreniaJ J McGrath
Queensland Brain Institute, University of Queensland, St Lucia, QLD, Australia
Transl Psychiatry 1:e14. 2011....
The association between delusional-like experiences, and tobacco, alcohol or cannabis use: a nationwide population-based surveySukanta Saha
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia
BMC Psychiatry 11:202. 2011..The aim of the study was to explore the association between DLE and three commonly used substances--tobacco, alcohol and cannabis...
Developmental vitamin D deficiency and risk of schizophrenia: a 10-year updateJohn J McGrath
Queensland Center for Mental Health Research, The Park Center for Mental Health, Wacol, Queensland 4076, Australia
Schizophr Bull 36:1073-8. 2010..This article provides a concise summary of the epidemiological and animal experimental research that has explored this hypothesis...
A systematic review of the association between common single nucleotide polymorphisms and 25-hydroxyvitamin D concentrationsJohn J McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Locked Bag 500, Richlands Q4077, Australia
J Steroid Biochem Mol Biol 121:471-7. 2010..Further research is required in order to clarify the genetic architecture underlying 25OHD serum concentrations, and to unravel the mechanisms of action responsible for these associations...
Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adultsJohn McGrath
Queensland Brain Institute, University of Queensland, St Lucia, Queensland, Australia
Arch Gen Psychiatry 67:440-7. 2010..The use of sibling pair analysis reduces the influence of unmeasured residual confounding...
The impact of nonlinear exposure-risk relationships on seasonal time-series data: modelling Danish neonatal birth anthropometric dataJohn McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Q4076, Australia
BMC Med Res Methodol 7:45. 2007..The aims of this paper are twofold: (a) to explore seasonal patterns in a large, Danish Medical Birth Register, and (b) to explore models based on seasonal exposures and a non-linear exposure-risk relationship...
The antecedents of schizophrenia: a review of birth cohort studiesJoy Welham
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia
Schizophr Bull 35:603-23. 2009..The aims of this article were to summarize key findings from BC studies in order to identify areas of convergence and to outline areas requiring further research...
Protein expression in the nucleus accumbens of rats exposed to developmental vitamin D deficiencyJohn McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Richlands, Australia
PLoS ONE 3:e2383. 2008..Because the nucleus accumbens has been implicated in neuropsychiatric disorders, in the current study we examined protein expression in this region in adult rats exposed to DVD deficiency..
Why schizophrenia epidemiology needs neurobiology--and vice versaJohn J McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland 4076, Australia
Schizophr Bull 35:577-81. 2009..We need to build shared discovery platforms that encourage greater cross-fertilization between schizophrenia epidemiology and basic neuroscience research...
Dissecting the heterogeneity of schizophrenia outcomesJohn McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland 4076, Australia
Schizophr Bull 34:247-8. 2008
No association between serum 25-hydroxyvitamin D3 level and performance on psychometric tests in NHANES IIIJohn McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia
Neuroepidemiology 29:49-54. 2007..We had the opportunity to examine the relationship between serum 25-hydroxyvitamin D(3) [25(OH)D] levels and performance on various cognitive tasks, based on a large, representative community sample...
Schizophrenia: a concise overview of incidence, prevalence, and mortalityJohn McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland 4076, Australia
Epidemiol Rev 30:67-76. 2008..In conclusion, the epidemiology of schizophrenia is characterized by prominent variability and gradients that can help guide future research...
Thought experiments on the incidence and prevalence of schizophrenia "under the influence" of cannabisJohn J McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia
Addiction 102:514-5; discussion 516-8. 2007
New directions in the epidemiology of schizophreniaJohn J McGrath
Queensland Brain Institute, University of Queensland, Brisbane, QLD
Med J Aust 190:S7-9. 2009..Epidemiology is good for generating candidate exposures but poor at proving them. Cross-disciplinary projects between epidemiology and neuroscience may help us understand the pathways leading to schizophrenia...
Hypotheses desert us, while data defend usJohn McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD, Australia
Schizophr Res 102:27-8. 2008
Growth in young adults who screen positive for non-affective psychosis: birth cohort studyJoy Welham
Queensland Centre for Mental Health Research, Park Centre for Mental Health, Queensland, Australia
Aust N Z J Psychiatry 43:61-7. 2009....
Paternal and maternal age as risk factors for psychosis: findings from Denmark, Sweden and AustraliaOssama El-Saadi
Queensland Centre for Schizophrenia Research, The Park Centre for Mental Health, Wacol, Queensland Q4076, Australia
Schizophr Res 67:227-36. 2004..The aim of the current study was to examine both paternal and maternal age as risk factors for the broader category of psychosis...
The prevalence and correlates of hallucinations in Australian adolescents: results from a national surveyJames Scott
Child and Youth Mental Health Service, Royal Children s Hospital, Herston, QLD, 4029, Australia
Schizophr Res 107:179-85. 2009..Further research may assist in understanding the variable trajectory of children and adolescents who hallucinate...
Correlates of delusion-like experiences in a non-psychotic community sampleDaniel Varghese
Department of Psychiatry, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia
Aust N Z J Psychiatry 42:505-8. 2008..The aim of the present study was to examine selected correlates of delusion-like experiences in a sample of non-psychotic individuals...
Psychopathology during childhood and adolescence predicts delusional-like experiences in adults: a 21-year birth cohort studyJames Scott
Child and Youth Mental Health Service, Royal Children s Hospital, Herston, Queensland, Australia
Am J Psychiatry 166:567-74. 2009..Community surveys have shown that many otherwise well individuals report delusional-like experiences. The authors examined psychopathology during childhood and adolescence as a predictor of delusional-like experiences in young adulthood...
Low maternal vitamin D as a risk factor for schizophrenia: a pilot study using banked seraJohn McGrath
Department of Psychiatry, Queensland Centre for Schizophrenia Research, University of Queensland, The Park Centre for Mental Health, Wacol Q4076, Australia
Schizophr Res 63:73-8. 2003..Evidence from epidemiology suggests that low maternal vitamin D may be a risk factor for schizophrenia...
The association between trauma and delusional-like experiencesSukanta Saha
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia
Psychiatry Res 189:259-64. 2011..Further understanding of biological and cognitive pathways is required to unravel the association between trauma exposure and delusional-like experiences...
A systematic review and meta-analysis of Northern Hemisphere season of birth studies in schizophreniaGeoffrey Davies
Queensland Centre for Mental Health Research, Wolston Park Hospital, Wacol, Australia
Schizophr Bull 29:587-93. 2003..271,p < 0.005). Furthermore, the shape of the seasonality in schizophrenia births varied by latitude band. These variations may encourage researchers to generate candidate seasonally fluctuating exposures...
A systematic review of the prevalence of schizophreniaSukanta Saha
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia
PLoS Med 2:e141. 2005..02). CONCLUSIONS: There is a wealth of data about the prevalence of schizophrenia. These gradients, and the variability found in prevalence estimate distributions, can provide direction for future hypothesis-driven research...
CTLA-4 single-nucleotide polymorphisms in a Caucasian population with schizophreniaAmanda L Jones
The University of Queensland, UQ Centre for Clinical Research, Brisbane, QLD 4029, Australia
Brain Behav Immun 23:347-50. 2009..These results suggest a role for the 3' UTR SNP and/or variants in high linkage disequilibrium with this SNP in the pathogenesis of schizophrenia...
Directional and fluctuating asymmetry in finger and a-b ridge counts in psychosis: a case-control studySukanta Saha
Queensland Centre for Schizophrenia Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia
BMC Psychiatry 3:3. 2003..Because ridges are fully formed by the end of the second trimester, they may provide clues to disturbed early development. The aim of this study was to assess these measures in a sample of patients with psychosis and normal controls...
A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodologyJohn McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Q4076, Australia
BMC Med 2:13. 2004..The aims of this review are to systematically identify studies related to the incidence of schizophrenia, to describe the key features of these studies, and to explore the distribution of rates derived from these studies...
Schizophrenia, vitamin D, and brain developmentAlan Mackay-Sim
School of Biomolecular and Biomedical Science, Griffith University, Brisbane, QLD 4111, Australia
Int Rev Neurobiol 59:351-80. 2004..quot; We also discuss the possibility of a broader set of environmental and genetic factors interacting via the nuclear hormone receptors to affect the development of the brain leading to schizophrenia...
Fibroblast and lymphoblast gene expression profiles in schizophrenia: are non-neural cells informative?Nicholas A Matigian
Queensland Institute of Medical Research, Herston, Queensland, Australia
PLoS ONE 3:e2412. 2008....
Association between trauma exposure and delusional experiences in a large community-based sampleJames Scott
Kids in Mind Research, Mater Children s Hospital, South Brisbane and Queensland Centre for Mental Health Research, Wacol, Queensland
Br J Psychiatry 190:339-43. 2007..Surveys have found that otherwise well individuals report delusional experiences. Previous studies have shown an association between psychotic symptoms and exposure to trauma...
Incidence of schizophrenia does not vary with economic status of the country: evidence from a systematic reviewSukanta Saha
Queensland Centre for Mental Health Research The Park Centre for Mental Health, Wacol, QLD, 4076, Australia
Soc Psychiatry Psychiatr Epidemiol 41:338-40. 2006..The aim of this study was to examine the association between economic status and the underlying incidence of schizophrenia based on a recently published systematic review of the incidence of schizophrenia...
Refining clinical phenotypes by contrasting ethnically different populations with schizophrenia from Australia, India and SarawakDuncan McLean
Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Queensland, Australia
Psychiatry Res 196:194-200. 2012..The AAO site difference, however, has no obvious cultural or measurement bias explanation. Therefore, this may be an ideal candidate for use in genetic studies, given that genetic variants affecting AAO have already been proposed...
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010Theo Vos
School of Population Health, Brisbane, QLD, Australia
Lancet 380:2163-96. 2012..Neither effort quantified uncertainty in prevalence or years lived with disability (YLDs)...
Paradoxical association between smoking and olfactory identification in psychosis versus controlsDuncan McLean
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland, 4076, Australia
Aust N Z J Psychiatry 38:81-3. 2004..Deficits in olfactory identification have been demonstrated in patients with schizophrenia. This study examined the interaction between smoking and olfactory identification in patients with psychotic disorders versus well controls...
Vitamin D in fetal brain developmentDarryl Eyles
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD, Australia
Semin Cell Dev Biol 22:629-36. 2011..Finally, we discuss the epidemiological data that suggests that vitamin D deficiency either in utero or in early life may have adverse neuropsychiatric implications...
Modelling disease frequency measures in schizophrenia epidemiologySukanta Saha
Queensland Centre for Mental He Research, The Park Centre for Mental Health, Locked Bag 500, Sumner Park, Q4074, Australia
Schizophr Res 104:246-54. 2008....
A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time?Sukanta Saha
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol Q4076, Australia
Arch Gen Psychiatry 64:1123-31. 2007..Despite improvements in mental health services in recent decades, it is unclear whether the risk of mortality in schizophrenia has changed over time...
No significant association between prenatal exposure poliovirus epidemics and psychosisMatthew Cahill
Queensland Centre for Schizophrenia Research, Wolston Park Hospital, Wacol, Australia
Aust N Z J Psychiatry 36:373-5. 2002..Further investigation of such inconsistencies may help elucidate candidate risk-modifying factors for schizophrenia...
The association between physical health and delusional-like experiences: a general population studySukanta Saha
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland, Australia
PLoS ONE 6:e18566. 2011..The aim of this study was to explore associations between the common physical disorders and DLE using a large population sample...
Prevention and schizophrenia--the role of dietary factorsJohn McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia
Schizophr Bull 37:272-83. 2011....
Queensland Centre for Mental Health Research: the first 17 yearsJohn McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health and Department of Psychiatry, University of Queensland, Brisbane, Queensland, Australia
Aust N Z J Psychiatry 39:533-41. 2005..To reflect on the establishment and evolution of the Queensland Centre for Mental Health Research...
Psychotic-like experiences in the general community: the correlates of CIDI psychosis screen items in an Australian sampleJames Scott
Mater Child and Youth Mental Health Service, Mater Children's Hospital, South Brisbane, Queensland, Australia
Psychol Med 36:231-8. 2006..CONCLUSIONS: Many of the correlates of endorsement of psychosis-screen items are also associated with psychosis. Unravelling the factors that contribute to this broader non-clinical phenotype will aid our understanding of psychosis...
Meta-analyses of the incidence and prevalence of schizophrenia: conceptual and methodological issuesSukanta Saha
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Locked Bag 500, Richlands, Q4077, Australia
Int J Methods Psychiatr Res 17:55-61. 2008..When used with appropriate caution, meta-analysis can complement the synthesis of frequency data in epidemiology; however, researchers interested in variation should not rely on meta-analysis alone...
A sensitive LC/MS/MS assay of 25OH vitamin D3 and 25OH vitamin D2 in dried blood spotsDarryl Eyles
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Q4076, Australia
Clin Chim Acta 403:145-51. 2009..While a number of methods exist to measure 25OHD in sera, none have been specifically developed to examine dried blood spots (DBS)...
Psychotic-like experiences in major depression and anxiety disorders: a population-based survey in young adultsDaniel Varghese
Department of Psychiatry, Princess Alexandra Hospital, Woolloongabba, Queensland 4102, Australia
Schizophr Bull 37:389-93. 2011..However, it is unclear if these experiences are associated with common mental disorders. The aim of this study was to examine the prevalence of psychotic-like experiences in those with affective and anxiety disorders...
Transient prenatal Vitamin D deficiency is associated with hyperlocomotion in adult ratsThomas H J Burne
Centre for Molecular Neurobiology, School of Biomolecular and Biomedical Science, Griffith University, Brisbane, QLD 4111, Australia
Behav Brain Res 154:549-55. 2004..Thus, transient prenatal Vitamin D deficiency induces hyperlocomotion in adulthood, without severe motor abnormalities...
Hyperlocomotion associated with transient prenatal vitamin D deficiency is ameliorated by acute restraintThomas H J Burne
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland 4076, Australia
Behav Brain Res 174:119-24. 2006..The time spent in the centre was not altered by prenatal diet or acute restraint. Thus, transient prenatal vitamin D deficiency induces a transient spontaneous hyperlocomotion in adulthood that is modulated by acute restraint stress...
Maintaining and updating semantic context in schizophrenia: an investigation of the effects of multiple remote primesHelen J Chenery
Center for Research in Language Processing and Linguistics, Division of Speech Pathology, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia
Psychiatry Res 126:241-52. 2004..The results support and extend the hypothesis that schizophrenia is associated with concurrent increases in tonic dopamine activity and decreases in phasic dopamine activity...
Maternal vitamin D3 deprivation and the regulation of apoptosis and cell cycle during rat brain developmentPauline Ko
School of Biomedical Sciences, University of Queensland, QLD 4072, Brisbane, Australia
Brain Res Dev Brain Res 153:61-8. 2004....
Substance misuse in patients with schizophrenia: epidemiology and managementDavid J Kavanagh
Department of Psychiatry, School of Medicine, University of Queensland, Herston, Queensland, Australia
Drugs 62:743-55. 2002..Several pharmacotherapies for substance misuse can be used safely in people with schizophrenia, but the evidence base is small and guidelines for their use are necessarily derived from experience in the general population...
Minor physical anomalies and quantitative measures of the head and face in patients with psychosisJohn McGrath
Queensland Centre for Schizophrenia Research, Wolston Park Hospital, Wacol Q4076, Australia
Arch Gen Psychiatry 59:458-64. 2002..The aim of this study was to examine minor physical anomalies and quantitative measures of the head and face in patients with psychosis vs healthy controls...
Vitamin D supplementation during the first year of life and risk of schizophrenia: a Finnish birth cohort studyJohn McGrath
Department of Psychiatry, University of Cambridge, Cambridge, UK
Schizophr Res 67:237-45. 2004..The aim of this study was to explore the association between the use of vitamin D supplements during the first year of life and risk of developing schizophrenia...
Association study of the dystrobrevin-binding gene with schizophrenia in Australian and Indian samplesElizabeth G Holliday
Queensland Centre for Mental Health Research, The Park, Centre for Mental Health, Wacol, Queensland, Australia
Twin Res Hum Genet 9:531-9. 2006..More comprehensive studies in multiple samples will be required to determine whether specific DTNBP1 variants function as risk factors for schizophrenia...
Advanced paternal age is associated with alterations in discrete behavioural domains and cortical neuroanatomy of C57BL/6J miceClaire J Foldi
Queensland Brain Institute, The University of Queensland, St Lucia, Queensland, Australia
Eur J Neurosci 31:556-64. 2010..Male APA mice had thinner cortices at birth and increased cortical volume as adults. This animal model may assist in exploring the mechanism of action linking APA with disorders such as schizophrenia and autism...
Developmental vitamin D deficiency alters dopamine-mediated behaviors and dopamine transporter function in adult female ratsJames P Kesby
School of Biomedical Science, University of Queensland, Brisbane, QLD, 4072, Australia
Psychopharmacology (Berl) 208:159-68. 2010..DVD-deficient adult rats show novelty-induced hyperlocomotion and an enhanced locomotor response to MK-801, which can be ameliorated by pretreatment with the antipsychotic drug haloperidol...
Variations in the incidence of schizophrenia: data versus dogmaJohn J McGrath
Queensland Centre for Mental Health Research, Park Centre for Mental Health, Wacol, QLD 4076 Australia
Schizophr Bull 32:195-7. 2006..In addition, the prevalence of schizophrenia is also characterized by prominent variation. The realization that schizophrenia is characterized by rich and informative gradients will serve as a catalyst for future research...
Seasonal fluctuations in birth weight and neonatal limb length; does prenatal vitamin D influence neonatal size and shape?John J McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia
Early Hum Dev 81:609-18. 2005..Birth weight is known to fluctuate with season of birth, however, there is little information about seasonal variation in neonatal anthropometric measures...
Age-at-first-registration for affective psychosis and schizophreniaJoy L Welham
Queensland Centre for Mental Health Research, University of Queensland, Wolston Park Hospital, Wacol, Australia
Schizophr Bull 30:849-53. 2004..This finding suggests that factors influencing age-at-first-registration for schizophrenia and affective psychosis may be similar, especially for females...
Event-related potential correlates of impaired visuospatial working memory in schizophreniaAllison M Cameron
Cognitive Psychophysiology Laboratory, Medical School, The University of Queensland, Herston, Queensland, Australia
Psychophysiology 40:702-15. 2003..The results indicate that patients with schizophrenia generate less maintenance phase neuronal activity during WM performance, especially under conditions of distraction...
Vitamin D3-implications for brain developmentJohn J McGrath
Queensland Centre for Schizophrenia Research, The Park Centre for Mental Health, Wacol, Australia
J Steroid Biochem Mol Biol 89:557-60. 2004..It remains to be seen if these processes are of clinical relevance in humans, but in light of the high rates of hypovitaminosis D in pregnant women and neonates, this area warrants further scrutiny...
Invited commentary: Gaining traction on the epidemiologic landscape of schizophreniaJohn J McGrath
Queensland Centre for Schizophrenia Research, Park Centre for Mental Health, University of Queensland, Wacol, Queensland 4076, Australia
Am J Epidemiol 158:301-4. 2003
The utility of neonatal dried blood spots for the assessment of neonatal vitamin D statusDarryl W Eyles
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland, Australia
Paediatr Perinat Epidemiol 24:303-8. 2010..They could be used for case-control studies investigating the association between perinatal vitamin D status and later health outcomes...
Season of birth is associated with anthropometric and neurocognitive outcomes during infancy and childhood in a general population birth cohortJohn J McGrath
Department of Psychiatry, University of Queensland, St Lucia QLD, Australia
Schizophr Res 81:91-100. 2006..Winter/spring birth, while associated with an increased risk of schizophrenia, is generally associated with superior outcomes with respect to physical and cognitive development...
Developmental vitamin D (DVD) deficiency in the rat alters adult behaviour independently of HPA functionDarryl W Eyles
Queensland Centre for Mental Health Research, Wacol, The School of Biomedical Sciences, The University of Queensland, Brisbane, and Perinatal Research Centre, Royal Brisbane and Women s Hospital, Herston, Australia
Psychoneuroendocrinology 31:958-64. 2006..We conclude that the behavioural alterations induced by DVD deficiency are due to some adverse event in brain development rather than via an alteration in stress response...
Developmental vitamin D deficiency alters MK 801-induced hyperlocomotion in the adult rat: An animal model of schizophreniaJames P Kesby
School of Biomedical Science, University of Queensland, Brisbane, Australia
Biol Psychiatry 60:591-6. 2006..In light of the putative association between low prenatal vitamin D and schizophrenia, the discrete behavioral differences associated with the DVD model may help elucidate the neurobiological correlates of schizophrenia...
Working memory correlates of three symptom clusters in schizophreniaAllison M Cameron
Cognitive Psychophysiology Laboratory, Medical School, The University of Queensland, Herston, Queensland, Australia
Psychiatry Res 110:49-61. 2002..The present study provides evidence that the positive, negative and disorganised symptom dimensions of the PANSS constitute independent clusters, associated with unique patterns of working memory impairment...
Evidence of altered prefrontal-thalamic circuitry in schizophrenia: an optimized diffusion MRI studyStephen E Rose
Centre for Magnetic Resonance, University of Queensland, Brisbane 4072, Australia
Neuroimage 32:16-22. 2006..001). This study has shown for the first time that MD measures offer an alternative strategy for investigating altered prefrontal-thalamic circuitry in schizophrenia...
Age-at-first-registration and heterogeneity in affective psychosesJoy L Welham
Queensland Centre for Schizophrenia Research, Wacol, Australia
Aust N Z J Psychiatry 37:66-9. 2003..This paper examines the influence of heterogeneity on the age-at-first-registration distribution for the ICD-9 diagnostic group 'affective psychosis'...
Developmental vitamin D (DVD) deficiency alters pup-retrieval but not isolation-induced pup ultrasonic vocalizations in the ratThomas H J Burne
Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia
Physiol Behav 102:201-4. 2011..We speculate that the altered maternal-pup interactions identified in the DVD model may impact on early periods of brain development and behaviour...
The neurodevelopmental hypothesis of schizophrenia: a review of recent developmentsJohn J McGrath
Queensland Centre for Schizophrenia Research, The Park Center for Mental Health, Wacol, QLD 4076, Australia
Ann Med 35:86-93. 2003..The NDH has provided great impetus to the schizophrenia research community. Recent versions of the hypothesis have encouraged more focused and testable hypotheses...
Neonatal vitamin D status and risk of schizophrenia: a population-based case-control studyJohn J McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia
Arch Gen Psychiatry 67:889-94. 2010..Clues from the epidemiology of schizophrenia suggest that low levels of developmental vitamin D may be associated with increased risk of schizophrenia...
The association between birth weight, season of birth and latitudeJohn J McGrath
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia
Ann Hum Biol 32:547-59. 2005..Birth weight is known to fluctuate with month of birth and with latitude; however the mechanisms underlying these gradients remain unclear...
Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brainDarryl W Eyles
Queensland Centre for Schizophrenia Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia
J Chem Neuroanat 29:21-30. 2005..The widespread distribution of 1alpha-OHase and the VDR suggests that Vitamin D may have autocrine/paracrine properties in the human brain...
Correlates of victimisation amongst people with psychosisBenjamin Chapple
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol (QLD) 4076, Australia
Soc Psychiatry Psychiatr Epidemiol 39:836-40. 2004..Models of care that address issues related to symptom relief, accommodation, and exposure to high-crime areas may reduce the rates of victimisation amongst those with psychotic disorders...
Swimming behaviour and post-swimming activity in Vitamin D receptor knockout miceThomas H J Burne
Neurobiology Program, Institute for Cell and Molecular Therapies, Griffith University, Brisbane, QLD 4111, Australia
Brain Res Bull 69:74-8. 2006..Differences in muscle strength may confound tests of activity that are used to infer an "anxious" phenotype...
Maternal vitamin D depletion alters neurogenesis in the developing rat brainXiaoying Cui
School of Biomedical Sciences, University of Queensland, Brisbane, QLD, Australia
Int J Dev Neurosci 25:227-32. 2007..These results show that vitamin D can regulate cell proliferation in the developing brain. Further studies are warranted to examine the underlying mechanisms for these findings...
Vitamin D deficiency during various stages of pregnancy in the rat; its impact on development and behaviour in adult offspringDarryl W Eyles
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD 4076, Australia
Psychoneuroendocrinology 32:227-34. 2007..These findings suggest there may be a therapeutic window for maternal dietary intervention in the DVD model of psychosis...
Developmental vitamin D deficiency alters adult behaviour in 129/SvJ and C57BL/6J miceLauren R Harms
School of Biomedical Sciences, Department of Physiology and Pharmacology, The University of Queensland, Brisbane, Queensland 4072, Australia
Behav Brain Res 187:343-50. 2008....
Cell cycle alterations in biopsied olfactory neuroepithelium in schizophrenia and bipolar I disorder using cell culture and gene expression analysesRichard D McCurdy
Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, QLD 4111, Australia
Schizophr Res 82:163-73. 2006....
Long-term trends in sunshine duration and its association with schizophrenia birth rates and age at first registration--data from Australia and the NetherlandsJohn McGrath
Queensland Centre for Schizophrenia Research, Department of Psychiatry, University of Queensland, Wolston Park Hospital, Q4076, Wacol, Australia
Schizophr Res 54:199-212. 2002....
Olfactory neural cells: an untapped diagnostic and therapeutic resource. The 2000 Ogura LectureChristopher Perry
Department of Surgery, University of Queensland, Australia
Laryngoscope 112:603-7. 2002..This is an overview of the cellular biology of upper nasal mucosal cells that have special characteristics that enable them to be used to diagnose and study congenital neurological diseases and to aid neural repair...
An on-line investigation of lexical ambiguity processing in schizophreniaDavid Copland
Center for Research in Language Processing and Linguistics, Department of Speech Pathology and Audiology, The University of Queensland, Brisbane, Australia
Brain Cogn 48:324-7. 2002..At 1250 ms ISI, a pattern of nonselective meaning facilitation was obtained. These results suggest an attentional breakdown in the sustained inhibition of meanings on the basis of lexical context...
1,25-dihydroxyvitamin D3 induces nerve growth factor, promotes neurite outgrowth and inhibits mitosis in embryonic rat hippocampal neuronsJillanne Brown
School of Biomedical Sciences, University of Queensland, Brisbane, QLD 4072, Australia
Neurosci Lett 343:139-43. 2003..The role of vitamin D(3) during brain development warrants closer scrutiny...
Tumor necrosis factor haplotype analysis amongst schizophrenia probands from four distinct populations in the Asia-Pacific regionHerlina Y Handoko
Queensland Centre for Schizophrenia Research, The Park, Centre for Mental Health, Wacol, Queensland, Australia
Am J Med Genet B Neuropsychiatr Genet 121:1-6. 2003..Taken together, these data provide no support for the involvement of TNF promoter variants TNF(-308), TNF(-376), and TNF(-238) in schizophrenia susceptibility within four ethnically distinct cohorts...
Behavioural characterization of vitamin D receptor knockout miceThomas H J Burne
Centre for Molecular Neurobiology, School of Biomolecular and Biomedical Science, Griffith University, Brisbane, QLD 4111, Australia
Behav Brain Res 157:299-308. 2005..Therefore, it appears that VDR -/- mice have muscular and motor impairments that significantly affects locomotor behaviour but seemingly no impairments in cognition as indicated by exploration, working memory or anxiety...
Developmental vitamin D3 deficiency induces alterations in immune organ morphology and function in adult offspringLouise Harvey
School of Biomedical Sciences, Department of Physiology and Pharmacology, The University of Queensland, Brisbane, Queensland 4072, Australia
J Steroid Biochem Mol Biol 121:239-42. 2010..Given an increased incidence of vitamin D3 deficiency in women of child-bearing age these findings may be highly relevant for autoimmune disorders with a developmental basis...
Maternal age and paternal age are associated with distinct childhood behavioural outcomes in a general population birth cohortSukanta Saha
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Locked Bag 500, Richlands Q4077, Australia
Schizophr Res 115:130-5. 2009..The aim of the study was to examine the relationship between paternal and maternal ages and selected behavioural measures in children using a large birth cohort...
Advanced paternal age is associated with impaired neurocognitive outcomes during infancy and childhoodSukanta Saha
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Richlands, Australia
PLoS Med 6:e40. 2009..The aim of this study was to examine the relationship between paternal age and performance on neurocognitive measures during infancy and childhood...
The incidence of Streptococcus pneumoniae otitis media is affected by the polymicrobial environment particularly Moraxella catarrhalis in a mouse nasal colonisation modelAjay Krishnamurthy
Capricornia Centre for Mucosal Immunology, CQUniversity, Queensland, Australia
Microbes Infect 11:545-53. 2009..The study has shown that the composition of bacteria in the nasal cavity and respiratory viral infection significantly affected the OM incidence rate, duration of infection and bacterial load (severity)...
Airway bacterial interactions and impact on host immune responsesJennelle Kyd
Institute for Health and Social Science Research, School of Medical and Applied Science, CQ University Australia, Rockhampton, QLD, Australia
Adv Otorhinolaryngol 72:116-20. 2011....
Combined prenatal and chronic postnatal vitamin D deficiency in rats impairs prepulse inhibition of acoustic startleThomas H J Burne
Centre for Molecular Neurobiology, School of Biomolecular and Biomedical Science, Griffith University, Brisbane, Queensland 4111, Australia
Physiol Behav 81:651-5. 2004..We conclude that combined prenatal and chronic postnatal hypovitaminosis D, but not early life hypovitaminosis D, alters PPI...
Executive control of working memory in schizophreniaJoanne Oram
Cognitive Psychophysiology Laboratory, Edith Cavell Building Medical School, University of Queensland, Herston Road, Herston, Queensland 4006, Australia
Psychiatry Res 135:81-90. 2005....
Developmental vitamin D deficiency alters dopamine turnover in neonatal rat forebrainJames P Kesby
School of Biomedical Science, University of Queensland, QLD 4072, Australia
Neurosci Lett 461:155-8. 2009..Correspondingly, expression of the enzyme required for this conversion, catechol-O-methyl transferase (COMT), was decreased. These results suggest that DVD-deficiency influences dopamine turnover during development...
Regulation of adult olfactory neurogenesis by insulin-like growth factor-IRichard D McCurdy
Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, QLD 4111, Australia
Eur J Neurosci 22:1581-8. 2005..These effects appear to be similar to the cellular effects of IGF-I in the developing nervous system...
The high prevalence of vitamin D insufficiency across Australian populations is only partly explained by season and latitudeIngrid A F van der Mei
Menzies Research Institute, University of Tasmania, Hobart, Australia
Environ Health Perspect 115:1132-9. 2007..Inadequate sun exposure and dietary vitamin D intake can result in vitamin D insufficiency. However, limited data are available on actual vitamin D status and predictors in healthy individuals in different regions and by season...
Transient prenatal vitamin D deficiency is associated with subtle alterations in learning and memory functions in adult ratsAxel Becker
O v Guericke University, Faculty of Medicine, Institute of Pharmacology and Toxicology, Leipziger Str 44, 39120 Magdeburg, Germany
Behav Brain Res 161:306-12. 2005..The behavioural phenotype associated with this animal model may provide insights into the neurobiological correlates of the cognitive impairments of schizophrenia...
Seasonal variation in birth weightJohn J McGrath
CMAJ 173:733; author reply 733-4. 2005
The urgent need to recommend an intake of vitamin D that is effectiveReinhold Vieth
Am J Clin Nutr 85:649-50. 2007
Associations between early development and outcome in schizophrenia--A 35-year follow-up of the Northern Finland 1966 Birth CohortErika Jaaskelainen
Department of Psychiatry, University of Oulu, Finland, P O Box 5000, 90014 University of Oulu, Finland
Schizophr Res 99:29-37. 2008..We conclude that risk factors for schizophrenia are not necessarily prognostic factors...
Thermal damage prediction for collagenous tissues part I: a clinically relevant numerical simulation incorporating heating rate dependent denaturationAlptekin Aksan
Center for Engineering in Medicine and Department of Surgical Services, Massachusetts General Hospital, Boston, MA 02114, USA
J Biomech Eng 127:85-97. 2005....
