Research Topics
| Jim ManosSummaryAffiliation: University of Sydney Country: Australia Publications
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Detail Information
Publications
Transcriptome analyses and biofilm-forming characteristics of a clonal Pseudomonas aeruginosa from the cystic fibrosis lungJim Manos
Department of Infectious Diseases and Immunology, University of Sydney, Sydney, Australia
J Med Microbiol 57:1454-65. 2008..This study extends our understanding of the transcriptomic and genetic differences between clonal and NC strains of P. aeruginosa from CF lung...
Gene expression characteristics of a cystic fibrosis epidemic strain of Pseudomonas aeruginosa during biofilm and planktonic growthJim Manos
Department of Infectious Diseases and Immunology, University of Sydney, Sydney, NSW, Australia
FEMS Microbiol Lett 292:107-14. 2009..Together, these properties may enhance long-term survival of AES-2 in CF lung and contribute to its transmissibility...
Phenotypic characterization of clonal and nonclonal Pseudomonas aeruginosa strains isolated from lungs of adults with cystic fibrosisPholawat Tingpej
Department of Infectious Diseases and Immunology, Blackburn Building DO6, University of Sydney, 2006 NSW, Australia
J Clin Microbiol 45:1697-704. 2007..Findings suggest that protease activity during chronic infection may contribute to the transmissibility or virulence of these clonal strains...
Pseudomonas aeruginosa AES-1 exhibits increased virulence gene expression during chronic infection of cystic fibrosis lungSharna Naughton
Department of Infectious Diseases and Immunology, University of Sydney, Sydney, Australia
PLoS ONE 6:e24526. 2011..Elucidation of these genes' roles could lead to targeted treatment strategies for chronically infected CF patients...
Gene expression of Pseudomonas aeruginosa in a mucin-containing synthetic growth medium mimicking cystic fibrosis lung sputumCarina Fung
Department of Infectious Diseases and Immunology, University of Sydney, Sydney, Australia
J Med Microbiol 59:1089-100. 2010..ASMDM thus appears to be highly suitable for gene expression studies of P. aeruginosa in CF...
Pseudomonas aeruginosa strains from the chronically infected cystic fibrosis lung display increased invasiveness of A549 epithelial cells over timeChristopher J Harmer
Bacterial Pathogens in Cystic Fibrosis Group, Department of Infectious Diseases and Immunology, Central Clinical School, Blackburn Building, University of Sydney, Sydney, NSW 2006, Australia
Microb Pathog 53:37-43. 2012..Defining mechanisms behind the increased invasiveness during chronic infection may help identify new therapeutic targets for CF patients...
Clinical profile of adult cystic fibrosis patients with frequent epidemic clones of Pseudomonas aeruginosaPholawat Tingpej
Department of Infectious Diseases and Immunology, University of Sydney, Sydney, New South Wales, Australia
Respirology 15:923-9. 2010..This study examines the frequency and virulence of P. aeruginosa frequent epidemic clones in the adult CF clinic at Royal Prince Alfred Hospital, Sydney, Australia...
Protease IV production in Pseudomonas aeruginosa from the lungs of adults with cystic fibrosisLucas Smith
Department of Infectious Diseases and Immunology, Blackburn Building DO61 University of Sydney, Sydney, Australia
J Med Microbiol 55:1641-4. 2006..Overall the findings suggest that protease IV plays an important role in the pathogenesis of P. aeruginosa infection in the CF lung...
