Research Topics
| Colleen K LooSummaryAffiliation: University of New South Wales Country: Australia Publications
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Detail Information
Publications
A review of the efficacy of transcranial magnetic stimulation (TMS) treatment for depression, and current and future strategies to optimize efficacyColleen K Loo
School of Psychiatry, University of NSW, Psychiatrist, Black Dog Institute and South Eastern Sydney Illawarra Area Health Service, Australia
J Affect Disord 88:255-67. 2005..Factors relevant to the efficacy of rTMS are discussed along with the implications of these for the further optimization of rTMS...
Stimulus waveform influences the efficacy of repetitive transcranial magnetic stimulationJanet L Taylor
Prince of Wales Medical Research Institute, Randwick, NSW, Australia
J Affect Disord 97:271-6. 2007..However, non-optimal coil orientation and high intensities of monophasic rTMS may have influenced previous results...
Cognitive impairment following electroconvulsive therapy--does the choice of anesthetic agent make a difference?Ross D MacPherson
Department of Anesthesia and Pain Management, Royal North Shore Hospital, Sydney, NSW, Australia
J ECT 24:52-6. 2008..This article reviews the current literature dealing with anesthesia and postoperative cognitive impairment in general and with regard to ECT in particular...
Speed of response in ultrabrief and brief pulse width right unilateral ECTColleen K Loo
School of Psychiatry, University of New South Wales, Sydney, Australia
Int J Neuropsychopharmacol 16:755-61. 2013..Further research with a larger randomized and blinded study is recommended...
Neuropsychological and mood effects of ketamine in electroconvulsive therapy: A randomised controlled trialColleen K Loo
School of Psychiatry, University of New South Wales, Sydney, NSW 2031, Australia St George Hospital, Sydney, NSW, Australia The Northside Clinic, Sydney, NSW, Australia Wesley Hospital, Kogarah, Sydney, NSW, Australia Black Dog Institute, Sydney, Australia Electronic address
J Affect Disord 142:233-40. 2012..This study tested whether the addition of ketamine reduced cognitive impairment and enhanced efficacy over a course of ECT, in a randomised, placebo-controlled, double-blind study...
Cognition in elderly patients receiving unilateral and bilateral electroconvulsive therapy: a prospective, naturalistic comparisonDaniel W O'Connor
Aged Mental Health Research Unit, Department of Psychological Medicine, Monash University, Melbourne, Australia
J Affect Disord 124:235-40. 2010..Little is known of the relative effectiveness and tolerability of the two placements in the treatment of elderly, severely depressed inpatients...
A comparison of RUL ultrabrief pulse (0.3 ms) ECT and standard RUL ECTColleen K Loo
School of Psychiatry, University of New South Wales, Sydney, Australia
Int J Neuropsychopharmacol 11:883-90. 2008..Cognitive outcomes were superior in the RUL-UB ECT group, particularly in the retention of verbal and visual information, as well as in retrograde autobiographical memory...
Transcranial direct current stimulation priming of therapeutic repetitive transcranial magnetic stimulation: a pilot studyColleen Loo
School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia
J ECT 25:256-60. 2009..Motor cortex experiments suggest that the effects of rTMS can be enhanced by first priming the same cortical area with transcranial direct current stimulation (tDCS). We explored this approach in depressed subjects...
The difficult-to-treat electroconvulsive therapy patient - Strategies for augmenting outcomesColleen K Loo
School of Psychiatry, University of N S W, Sydney, Australia
J Affect Disord 124:219-27. 2010....
A sham-controlled trial of left and right temporal rTMS for the treatment of auditory hallucinationsC K Loo
School of Psychiatry, University of NSW and Black Dog Institute, Sydney, Australia
Psychol Med 40:541-6. 2010..Several studies have reported reduction of auditory hallucinations (AH) after repetitive transcranial magnetic stimulation (rTMS) to the left temporal cortex. This study explored the effects of rTMS to the left and right temporal cortex...
A double-blind, sham-controlled trial of transcranial direct current stimulation for the treatment of depressionColleen K Loo
School of Psychiatry, University of New South Wales, Sydney, Australia
Int J Neuropsychopharmacol 13:61-9. 2010..It is recommended that the efficacy of tDCS in depression be further evaluated over a longer treatment period, using enhanced stimulation parameters...
Augmentation strategies in electroconvulsive therapyColleen Loo
School of Psychiatry, University of New South Wales, Sydney, Australia
J ECT 26:202-7. 2010..Preliminary evidence suggests that ketamine and ECT may have synergistic antidepressant effects, although this needs to be further examined in randomized controlled trials...
Physical treatments for bipolar disorder: a review of electroconvulsive therapy, stereotactic surgery and other brain stimulation techniquesColleen Loo
School of Psychiatry, University of New South Wales, Sydney, Australia
J Affect Disord 132:1-13. 2011..Despite pharmacological advances, bipolar disorder continues to be difficult to treat. This article reviews the evidence base for the use of electroconvulsive therapy (ECT) and other brain stimulation therapies in bipolar disorder...
Mental health legislation and psychiatric treatments in NSW: electroconvulsive therapy and deep brain stimulationColleen Loo
School of Psychiatry, University of NSW, St George Hospital, Gray Street, Kogarah, NSW 2217, Australia
Australas Psychiatry 18:417-25. 2010....
Predictors of response to ultrabrief right unilateral electroconvulsive therapyColleen K Loo
School of Psychiatry, University of NSW, Sydney, Australia
J Affect Disord 130:192-7. 2011..In many countries it is gradually being adopted into clinical practice and further information on predictors of response is needed...
Transcranial direct current stimulation for depression: 3-week, randomised, sham-controlled trialColleen K Loo
School of Psychiatry, University of New South Wales, Sydney, Australia
Br J Psychiatry 200:52-9. 2012..Preliminary evidence suggests transcranial direct current stimulation (tDCS) has antidepressant efficacy...
The NSW Mental Health Bill 2007: implications for the provision of electroconvulsive therapyColleen Loo
School of Psychiatry, University of NSW, St George Hospital, and Psychiatrist, Black Dog Institute, Sydney, NSW, Australia
Australas Psychiatry 15:457-60. 2007..CONCLUSIONS: New limits introduced in the Mental Health Bill 2007 may have potentially detrimental consequences for ECT therapy in involuntary patients and may inadvertently result in the provision of suboptimal ECT to these patients...
A review of the safety of repetitive transcranial magnetic stimulation as a clinical treatment for depressionColleen K Loo
School of Psychiatry, University of New South Wales, Sydney, Australia
Int J Neuropsychopharmacol 11:131-47. 2008..Long-term effects of repeated rTMS sessions are as yet unknown. When given within recommended guidelines, the overall safety profile of rTMS is good, and supports its further development as a clinical treatment...
A report on mood and cognitive outcomes with right unilateral ultrabrief pulsewidth (0.3 ms) ECT and retrospective comparison with standard pulsewidth right unilateral ECTColleen Loo
School of Psychiatry, University of N S W, Australia
J Affect Disord 103:277-81. 2007..This study explored the potential of a novel approach, ultrabrief pulsewidth (0.3 ms) right unilateral (RUL-UB) ECT, to minimise cognitive effects while preserving efficacy...
Double-blind controlled investigation of transcranial magnetic stimulation for the treatment of resistant major depressionC Loo
Mood Disorders Unit, Prince of Wales Hospital, Randwick, N S W, Australia
Am J Psychiatry 156:946-8. 1999..The efficacy and safety of left prefrontal repetitive transcranial magnetic stimulation (rTMS) for treating resistant major depression were examined in a double-blind, controlled study...
Supraorbital edema induced by electroconvulsive therapyColleen K Loo
School of Psychiatry, University of NSW, Sydney, Australia
J ECT 21:249-50. 2005..Trauma during ECT, allergic reaction to anesthetic agents, and complications of manual ventilation were found to be unlikely causes. The supraorbital edema occurred as an isolated, benign, complication of ECT and resolved spontaneously...
Transcranial magnetic stimulation in adolescent depressionColleen Loo
School of Psychiatry, University of New South Wales, Australia
Australas Psychiatry 14:81-5. 2006..There are few safe and effective biological treatments for major depression in adolescents. We aimed to report the use of repetitive transcranial magnetic stimulation (rTMS) as a treatment for adolescents with this condition...
Recent advances in optimizing electroconvulsive therapyColleen K Loo
Black Dog Institute, Hospital Rd, Prince of Wales Hospital, Barker St, Sydney, New South Wales 2031, Australia
Aust N Z J Psychiatry 40:632-8. 2006..Clinical practice should be guided by a careful appraisal of the available evidence for alternative approaches in ECT technique...
A sham-controlled trial of the efficacy and safety of twice-daily rTMS in major depressionColleen K Loo
School of Psychiatry, University of NSW and Black Dog Institute, Sydney, Australia
Psychol Med 37:341-9. 2007..Studies of repetitive transcranial magnetic stimulation (rTMS) in depression have mostly involved once-daily treatment, with positive but modest clinical results. This study tested the efficacy and safety of twice-daily rTMS over 2 weeks...
Fronto-extracephalic transcranial direct current stimulation as a treatment for major depression: an open-label pilot studyDonel M Martin
Black Dog Institute, School of Psychiatry, University of New South Wales, Sydney, Australia
J Affect Disord 134:459-63. 2011..This study investigated the efficacy and safety of tDCS given with a fronto-extracephalic (F-EX) montage...
Hypomania induction in a patient with bipolar II disorder by transcranial direct current stimulation (tDCS)Verònica Gálvez
School of Psychiatry, University of New South Wales, Sydney, Australia
J ECT 27:256-8. 2011..When the reference cathodal electrode in tDCS is moved from the cranium to an extracephalic position, larger areas of both cerebral hemispheres are stimulated, with potential implications for both efficacy and safety...
A study using transcranial magnetic stimulation to investigate motor mechanisms in psychomotor retardation in depressionColleen K Loo
School of Psychiatry, University of New South Wales, Sydney, Australia
Int J Neuropsychopharmacol 11:935-46. 2008..Our study suggests that although the motor pathway from the motor cortex to the muscle is unimpaired, psychomotor retardation in depression is characterized by a reduced ability to drive the motor cortex...
Repetitive transcranial magnetic stimulation for the treatment of obsessive compulsive disorder: a double-blind controlled investigationPerminder S Sachdev
School of Psychiatry, University of New South Wales, Australia
Psychol Med 37:1645-9. 2007..To determine the efficacy and tolerability of repetitive transcranial magnetic stimulation (rTMS) as a treatment for obsessive compulsive disorder (OCD) in a double-blind placebo-controlled study...
The effect of electrode placement and pulsewidth on asystole and bradycardia during the electroconvulsive therapy stimulusPatrick T Stewart
School of Psychiatry, University of New South Wales, Sydney, Australia
Int J Neuropsychopharmacol 14:585-94. 2011..Bifrontal ECT was associated with the lowest risk of bradycardia and asystole during ECT and should be considered for patients at risk of arrhythmias and prolonged asystole during ECT...
Daily transcranial direct current stimulation (tDCS) leads to greater increases in cortical excitability than second daily transcranial direct current stimulationAngelo Alonzo
School of Psychiatry, University of New South Wales, Black Dog Institute, Sydney, Australia
Brain Stimul 5:208-13. 2012..However, the optimal frequency at which tDCS sessions should be administered is unknown...
Continuation transcranial direct current stimulation for the prevention of relapse in major depressionDonel M Martin
Black Dog Institute, School of Psychiatry, University of New South Wales, Sydney, Australia
J Affect Disord 144:274-8. 2013..Little is known, however, of the duration of antidepressant effects following acute treatment. In this study, we describe the use of continuation tDCS treatment for up to 6 months following clinical response to an acute treatment course...
Comparison of depressive episodes in bipolar disorder and in major depressive disorder within bipolar disorder pedigreesPhilip B Mitchell
UNSW School of Psychiatry, Prince of Wales Hospital, Randwick, Australia
Br J Psychiatry 199:303-9. 2011....
Repetitive transcranial magnetic stimulation as treatment for anxiety disordersMelissa Pigot
School of Psychiatry, University of New South Wales, Black Dog Institute, Prince of Wales Hospital, Randwick, NSW 2031, Australia
Expert Rev Neurother 8:1449-55. 2008..With advances in neuroimaging technology, this understanding is likely to be more accessible than it has been in the past...
Transcranial magnetic stimulation for the deficit syndrome of schizophrenia: a pilot investigationPerminder Sachdev
School of Psychiatry, University of New South Wales, Sydney, Australia
Psychiatry Clin Neurosci 59:354-7. 2005..Repetitive transcranial magnetic stimulation as a treatment of the deficit syndrome of schizophrenia is feasible, safe and may be beneficial. A systematic study in randomized control trials would be appropriate...
Induction of hypomanic episode with transcranial direct current stimulationAbraham Patrick Arul-Anandam
School of Psychiatry, University of New South Wales, Sydney, Australia
J ECT 26:68-9. 2010....
Valid assessment of the clinical features of depression by relatives appears to slip under the RADARGordon Parker
School of Psychiatry, University of New South Wales and Black Dog Institute, Price of Wales Hospital, Sydney, Australia
Aust N Z J Psychiatry 37:92-6. 2003..We report on the development of an observational measure designed for completion by relatives, the Recent Appearance of Depression Assessed by Relatives (RADAR), and consider its validity...
A computational model of direct brain stimulation by electroconvulsive therapySiwei Bai
Graduate School of Biomedical Engineering, Faculty of Engineering, University of New South Wales UNSW, Australia
Conf Proc IEEE Eng Med Biol Soc 2010:2069-72. 2010..Results suggested that this model is able to reproduce direct stimulation of the cortex during the application of ECT...
Paired associative stimulation increases motor cortex excitability more effectively than theta-burst stimulationMichael J Player
School of Psychiatry, University of New South Wales, Sydney, Australia
Clin Neurophysiol 123:2220-6. 2012..To examine the effects of theta burst stimulation (TBS) and paired associative stimulation (PAS) on excitability in the human motor cortex...
Transcranial direct current stimulation treatment protocols: should stimulus intensity be constant or incremental over multiple sessions?Verònica Gálvez
School of Psychiatry, University of New South Wales, Sydney, Australia
Int J Neuropsychopharmacol 16:13-21. 2013..This study demonstrated that, in the motor cortex, administration of tDCS five times per week whether at a constant intensity or at a gradually increasing intensity was equally effective in increasing cortical excitability...
Diagnosis and monitoring of bipolar disorder in general practicePhilip B Mitchell
Black Dog Institute, Prince of Wales Hospital, and School of Psychiatry, University of New South Wales, Sydney, NSW
Med J Aust 193:S10-3. 2010..Daily mood charts are useful for providing an overview of patient progress and for identifying and managing early warning signs. Families and carers can also play an active role in supporting patients with bipolar disorder...
Transcranial direct current stimulation: a new tool for the treatment of depression?Abraham P Arul-Anandam
School of Psychiatry, University of New South Wales, Sydney, Australia
J Affect Disord 117:137-45. 2009..We briefly review tDCS clinical trials for MDD, and then consider its mechanisms of action, identifying potential avenues for future research...
Transcranial magnetic stimulation for depressionPhilip B Mitchell
School of Psychiatry, University of New South Wales, Black Dog Institute, Prince of Wales Hospital, Randwick, Australia
Aust N Z J Psychiatry 40:406-13. 2006..To review the accumulated literature on the efficacy, safety and predictors of response for repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression...
Pharmacological attenuation of electroconvulsive therapy--induced cognitive deficits: theoretical background and clinical findingsMelissa Pigot
School of Psychiatry, University of New South Wales, Black Dog Institute, Sydney, Australia
J ECT 24:57-67. 2008....
Transcranial magnetic stimulation: promise for the future?Colleen Loo
Sydney, NSW, Australia
Australas Psychiatry 12:409-10. 2004
Effects of different frequencies of transcranial magnetic stimulation (TMS) on the forced swim test model of depression in ratsPerminder S Sachdev
School of Psychiatry, University of New South Wales, and Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia
Biol Psychiatry 51:474-9. 2002..e., repeating the Swim Test) requires further validation...
