Research Topics
| Michelle M LoeligerSummaryAffiliation: University of Melbourne Country: Australia Publications
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Detail Information
Publications
Cerebral outcomes in a preterm baboon model of early versus delayed nasal continuous positive airway pressureMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, 3010, Victoria, Australia
Pediatrics 118:1640-53. 2006....
BDNF increases survival of retinal dopaminergic neurons after prenatal compromiseMichelle M Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Melbourne, Victoria, Australia
Invest Ophthalmol Vis Sci 49:1282-9. 2008....- Immunocytochemical development of the guinea pig retinaMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Grattan St, Melbourne, VIC 3010, Australia
Exp Eye Res 80:9-21. 2005..Thus, in the guinea pig retina, the amacrine and horizontal cell populations investigated in this study are fully mature prior to birth... 
Developmental and neuropathological consequences of ductal ligation in the preterm baboonMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria 3010, Australia
Pediatr Res 65:209-14. 2009..Surgical ligation of the PDA does not increase the incidence of brain injury and may be beneficial if the PDA is contributing to persistent pulmonary and hemodynamic instability...- Vulnerability of dopaminergic amacrine cells and optic nerve myelination to prenatal endotoxin exposureMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Melbourne, Victoria, Australia
Invest Ophthalmol Vis Sci 48:472-8. 2007..The purpose of this study was to investigate the effects of fetal inflammation induced by exposure to endotoxin on the structure and neurochemistry of the retina and optic nerve... - Chronic placental insufficiency affects retinal development in the guinea pigMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Victoria, Australia
Invest Ophthalmol Vis Sci 45:2361-7. 2004.... - Chronic placental insufficiency and foetal growth restriction lead to long-term effects on postnatal retinal structureMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Victoria, Australia
Clin Experiment Ophthalmol 31:250-3. 2003.... - Ibuprofen treatment for closure of patent ductus arteriosus is not associated with increased risk of neuropathologyMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Melbourne, Victoria 3010, Australia
Pediatr Res 68:298-302. 2010..No overt cerebellar alterations were observed in either group. Ibuprofen treatment for PDA closure in the preterm baboon neonate is not associated with any increased risk of neuropathology or alterations to brain growth and development... - Extracellular glutamate levels and neuropathology in cerebral white matter following repeated umbilical cord occlusion in the near term fetal sheepM Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, 3010, Victoria, Australia
Neuroscience 116:705-14. 2003..We conclude that, in the unanesthetised fetus in utero, glutamatergic processes are associated with umbilical cord occlusion-induced brain damage in the cerebral white matter... - Cerebellar development in a baboon model of preterm delivery: impact of specific ventilatory regimesSandra M Rees
Department of Anatomy Cell Biology, University of Melbourne, Victoria, Australia
J Neuropathol Exp Neurol 68:605-15. 2009..001) and was higher in DnCPAP than EnCPAP animals (p < 0.05). These results indicate that respiratory regimens can influence cerebellar development and that early compared with delayed extubation to nCPAP seems to be beneficial... - Erythropoietin protects the developing retina in an ovine model of endotoxin-induced retinal injuryMichelle M Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria, Australia
Invest Ophthalmol Vis Sci 52:2656-61. 2011..Using an ovine model, the authors investigated the neuroprotective potential of recombinant human erythropoietin (rhEPO) on retinal injury induced by intrauterine inflammation... - Fetal growth restriction induced by chronic placental insufficiency has long-term effects on the retina but not the optic nerveMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, 3010 Victoria, Australia
Invest Ophthalmol Vis Sci 46:3300-8. 2005..This study was undertaken to determine whether prenatal exposure to a chronic compromise sufficient to cause fetal growth restriction (FGR) results in long-term alterations to the retina and optic nerve... - High-frequency oscillatory ventilation is not associated with increased risk of neuropathology compared with positive pressure ventilation: a preterm primate modelMichelle Loeliger
Anatomy and Cell Biology, University of Melbourne, Victoria, Australia
Pediatr Res 66:545-50. 2009..LV-PPV and HFOV ventilation in prematurely delivered animals is associated with decreased brain growth and an increase in subtle neuropathologies; HFOV may minimize adverse effects on brain growth... - Prenatally compromised neurons respond to brain-derived neurotrophic factor treatment in vitroTodd A Briscoe
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria, Australia
Neuroreport 17:1385-9. 2006..Thus, brain-derived neurotrophic factor can influence the growth of compromised fetal neurons supporting its therapeutic use following chronic placental insufficiency... - Erythropoietin is neuroprotective in a preterm ovine model of endotoxin-induced brain injurySandra Rees
Department of Anatomy and Cell Biology, University of Melbourne, Victoria, Australia
J Neuropathol Exp Neurol 69:306-19. 2010..This is the first study in a long-gestation species to demonstrate the neuroprotective potential of rhEPO in reducing fetal brain and optic nerve injury after LPS exposure... - Effects of umbilical cord occlusion in late gestation on the ovine fetal brain and retinaJhodie R Duncan
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Australia
J Soc Gynecol Investig 11:369-76. 2004..Our aim was to assess quantitatively the persistent consequences of UCO on the developing brain; we also examined the retina... - Effects of exposure to chronic placental insufficiency on the postnatal brain and retina in sheepJhodie R Duncan
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria, Australia
J Neuropathol Exp Neurol 63:1131-43. 2004..These alterations in the brain can apparently persist from fetal life or become established after birth; some changes that were present in the fetus at term did not persist into postnatal life... - Inhaled nitric oxide: effects on cerebral growth and injury in a baboon model of premature deliverySandra M Rees
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria, 3010, Australia
Pediatr Res 61:552-8. 2007..Overall, iNO did not alter the extent of brain damage but did result in the presence of hematomas. These results do not confirm any protective or major injurious effect of nitric oxide therapy on the developing brain... - Chronic placental insufficiency has long-term effects on auditory function in the guinea pigAlexandra E Rehn
Department of Anatomy and Cell Biology, The University of Melbourne, Parkville, VIC 3010, Australia
Hear Res 166:159-65. 2002..The results suggest subtle deficits in neural conduction in the PC guinea pig at maturity, and may have implications for speech perception abilities of low birth weight or prenatally affected infants... - The fetal brainstem is relatively spared from injury following intrauterine hypoxemiaMary Tolcos
Department of Anatomy and Cell Biology, The University of Melbourne, Parkville, Victoria 3010, Australia
Brain Res Dev Brain Res 143:73-81. 2003..We suggest that the absence of marked structural or neurochemical alterations in the brainstem is most likely due to the maintenance of oxygen delivery to the brainstem during fetal hypoxemia... - Investigating structural and biochemical correlates of ganglion cell dysfunction in streptozotocin-induced diabetic ratsBang V Bui
Department of Optometry and Vision Sciences, University of Melbourne, Parkville, Victoria 3010, Australia
Exp Eye Res 88:1076-83. 2009....