Andrew R Lloyd

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. doi request reprint Safety and effectiveness of a nurse-led outreach program for assessment and treatment of chronic hepatitis C in the custodial setting
    Andrew R Lloyd
    Inflammation and Infection Research Centre, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Clin Infect Dis 56:1078-84. 2013
  2. pmc Incidence of primary hepatitis C infection and risk factors for transmission in an Australian prisoner cohort
    Suzy Teutsch
    School of Medical Sciences, The University of New South Wales, Sydney, New South Wales, Australia
    BMC Public Health 10:633. 2010
  3. pmc Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr virus
    Suzanne D Vernon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 6:15. 2006
  4. pmc Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution
    William C Reeves
    Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    BMC Health Serv Res 3:25. 2003
  5. pmc Fatigue states after cancer treatment occur both in association with, and independent of, mood disorder: a longitudinal study
    David Goldstein
    Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia
    BMC Cancer 6:240. 2006
  6. ncbi request reprint Host and viral factors in the immunopathogenesis of primary hepatitis C virus infection
    Andrew R Lloyd
    Centre for Infection and Inflammation Research, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia
    Immunol Cell Biol 85:24-32. 2007
  7. doi request reprint Comment on "Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome"
    Andrew Lloyd
    Centre for Infection and Inflammation Research, University of New South Wales, Sydney, Australia 2052
    Science 328:825; author reply 825. 2010
  8. ncbi request reprint Virological responses during treatment for recent hepatitis C virus: potential benefit for ribavirin use in HCV/HIV co-infection
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales UNSW, Sydney, Australia
    AIDS 26:1653-61. 2012
  9. pmc Effect of pegylated interferon-α-2a treatment on mental health during recent hepatitis C virus infection
    Maryam Alavi
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    J Gastroenterol Hepatol 27:957-65. 2012
  10. ncbi request reprint Clearance of hepatitis C viremia associated with cellular immunity in the absence of seroconversion in the hepatitis C incidence and transmission in prisons study cohort
    Jeffrey J Post
    Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia
    J Infect Dis 189:1846-55. 2004

Detail Information

Publications44

  1. doi request reprint Safety and effectiveness of a nurse-led outreach program for assessment and treatment of chronic hepatitis C in the custodial setting
    Andrew R Lloyd
    Inflammation and Infection Research Centre, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Clin Infect Dis 56:1078-84. 2013
    ....
  2. pmc Incidence of primary hepatitis C infection and risk factors for transmission in an Australian prisoner cohort
    Suzy Teutsch
    School of Medical Sciences, The University of New South Wales, Sydney, New South Wales, Australia
    BMC Public Health 10:633. 2010
    ..Previous studies of HCV incidence have been based on small case numbers and have not distinguished risk events in prison from those in the community...
  3. pmc Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr virus
    Suzanne D Vernon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 6:15. 2006
    ..The objective of this pilot study was to determine the gene expression correlates of post-infective fatigue following acute Epstein Barr virus (EBV) infection...
  4. pmc Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution
    William C Reeves
    Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    BMC Health Serv Res 3:25. 2003
    ..Difficulties with accurate case ascertainment contribute to this ignorance...
  5. pmc Fatigue states after cancer treatment occur both in association with, and independent of, mood disorder: a longitudinal study
    David Goldstein
    Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia
    BMC Cancer 6:240. 2006
    ..We sought to examine the longitudinal relationships between fatigue and mood disorder in women treated with adjuvant therapy for early stage breast cancer...
  6. ncbi request reprint Host and viral factors in the immunopathogenesis of primary hepatitis C virus infection
    Andrew R Lloyd
    Centre for Infection and Inflammation Research, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia
    Immunol Cell Biol 85:24-32. 2007
    ..A growing body of evidence has implicated polymorphisms in both innate and adaptive immune response genes as determinants of viral clearance in individuals infected with HCV...
  7. doi request reprint Comment on "Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome"
    Andrew Lloyd
    Centre for Infection and Inflammation Research, University of New South Wales, Sydney, Australia 2052
    Science 328:825; author reply 825. 2010
    ..However, the cases with CFS and the control subjects in their study are poorly described and unlikely to be representative. Independent replication is a critical first step before accepting the validity of this finding...
  8. ncbi request reprint Virological responses during treatment for recent hepatitis C virus: potential benefit for ribavirin use in HCV/HIV co-infection
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales UNSW, Sydney, Australia
    AIDS 26:1653-61. 2012
    ..This study evaluated early virological decline during recent HCV therapy in HIV-uninfected individuals receiving pegylated interferon (PEG-IFN) monotherapy and HIV-infected individuals receiving PEG-IFN/RBV...
  9. pmc Effect of pegylated interferon-α-2a treatment on mental health during recent hepatitis C virus infection
    Maryam Alavi
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    J Gastroenterol Hepatol 27:957-65. 2012
    ..Data on the effect of HCV treatment on mental health among injecting drug users (IDUs) are limited. We assessed mental health during treatment of recently acquired HCV, within a predominantly IDU population...
  10. ncbi request reprint Clearance of hepatitis C viremia associated with cellular immunity in the absence of seroconversion in the hepatitis C incidence and transmission in prisons study cohort
    Jeffrey J Post
    Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia
    J Infect Dis 189:1846-55. 2004
    ..These cases highlight the potential for cellular immune responses against HCV to facilitate viral clearance, responses that may model those required for effective HCV vaccination...
  11. pmc Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection
    Jason Grebely
    National Centre in HIV Epidemiology and Clinical Research NCHECR, University of New South Wales UNSW, Sydney, Australia
    Hepatology 52:1216-24. 2010
    ..Early therapeutic intervention could be recommended for individuals with unfavorable IL28B genotypes...
  12. pmc Adherence to treatment for recently acquired hepatitis C virus (HCV) infection among injecting drug users
    Jason Grebely
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    J Hepatol 55:76-85. 2011
    ..We assessed 80/80 adherence (≥80% of PEG-IFN doses, ≥80% treatment), on-treatment adherence, and treatment completion in a study of treatment of recent HCV infection (ATAHC)...
  13. ncbi request reprint Prevalence of production of virus-specific interferon-gamma among seronegative hepatitis C-resistant subjects reporting injection drug use
    Anthony J Freeman
    Department of Pathology, School of Medical Sciences, The University of New South Wales, Sydney, New South Wales, Australia
    J Infect Dis 190:1093-7. 2004
    ..Vaccine strategies to mimic this response may provide protection against persistent HCV infection...
  14. ncbi request reprint The presence of an intrahepatic cytotoxic T lymphocyte response is associated with low viral load in patients with chronic hepatitis C virus infection
    Anthony J Freeman
    Viral Hepatitis Research, Gastrointestinal and Liver Unit, The Prince of Wales Hospital, Barker Street, Randwick, Sydney, NSW 2031, Australia
    J Hepatol 38:349-56. 2003
    ..The role of cytotoxic T lymphocytes (CTL) in limiting viral replication and producing hepatocellular injury in patients with chronic hepatitis C virus (HCV) infection is controversial...
  15. ncbi request reprint Expression of the chemokine IP-10 (CXCL10) by hepatocytes in chronic hepatitis C virus infection correlates with histological severity and lobular inflammation
    Charles E Harvey
    Department of Gastroenterology, Prince of Wales Hospital, Sydney, New South Wales, Australia
    J Leukoc Biol 74:360-9. 2003
    ....
  16. doi request reprint Peripheral blood gene expression in postinfective fatigue syndrome following from three different triggering infections
    Sally Galbraith
    School of Mathematics and Statistics, Faculty of Science, University of New South Wales, Sydney, Australia
    J Infect Dis 204:1632-40. 2011
    ..Previous cross-sectional case-control studies of CFS have suggested that unique gene expression signatures are evident in peripheral blood samples...
  17. doi request reprint Frequent multiple hepatitis C virus infections among injection drug users in a prison setting
    Son T Pham
    School of Biotechnology and Biomolecular Sciences, Faculty of Science, Sydney, Australia
    Hepatology 52:1564-72. 2010
    ..Spontaneous clearance of viruses from one subtype and persistence of the other subtype after mixed infection was observed in eight subjects. In these subjects, the virus with higher HCV RNA levels superseded the other...
  18. pmc Risk factors for hepatitis C infection and perception of antibody status among male prison inmates in the Hepatitis C Incidence and Transmission in Prisons Study cohort, Australia
    Jennifer A Gates
    National Drug and Alcohol Research Centre, UNSW, Sydney, 2052, Australia
    J Urban Health 81:448-52. 2004
    ..Prisons are likely to remain an important site for the diagnosis of HCV infection and targeted interventions aimed at risk reduction among inmates with low education levels and a previous imprisonment history...
  19. pmc Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection
    Rowena A Bull
    School of Medical Sciences, University of New South Wales, Australia
    PLoS Pathog 7:e1002243. 2011
    ..These results provide the first detailed analysis of early within-host evolution of HCV, indicating strong selective forces limit viral evolution in the acute phase of infection...
  20. pmc Plasma interferon-gamma-inducible protein-10 (IP-10) levels during acute hepatitis C virus infection
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    Hepatology 57:2124-34. 2013
    ..hepatology 2013;)...
  21. ncbi request reprint Establishment of a successful assessment and treatment service for Australian prison inmates with chronic hepatitis C
    Leng Boonwaat
    Blood Borne Viruses and Sexual Assault Services, Population Health, Justice Health, Sydney, NSW, Australia
    Med J Aust 192:496-500. 2010
    ..To evaluate the assessment and treatment outcomes of a prison hepatitis service...
  22. doi request reprint Cytokine polymorphisms have a synergistic effect on severity of the acute sickness response to infection
    Ute Vollmer-Conna
    School of Psychiatry and 2Centre for Infection and Inflammation Research, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Clin Infect Dis 47:1418-25. 2008
    ..The genetic determinants of severity of the acute sickness response have not previously been explored...
  23. ncbi request reprint Postinfective fatigue syndrome is not associated with altered cytokine production
    Ute Vollmer-Conna
    School of Psychiatry, University of New South Wales, Sydney University, Sydney, Australia
    Clin Infect Dis 45:732-5. 2007
    ..No significant differences were found. Ongoing production of the cytokines examined does not play a role in postinfective fatigue syndrome...
  24. doi request reprint Alterations in immune function are associated with liver enzyme elevation in HIV and HCV co-infection after commencement of combination antiretroviral therapy
    Barbara Anne Cameron
    Inflammation and Infection Research Centre, School of Medical Sciences, University of New South Wales, Sydney, NSW, 2052, Australia
    J Clin Immunol 31:1079-83. 2011
    ....
  25. doi request reprint Cohort Profile: The International Collaboration of Incident HIV and Hepatitis C in Injecting Cohorts (InC3) Study
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, New South Wales, Australia, Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA, CRCHUM, Universite de Montreal, Montreal, Quebec, Canada, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA, Harvard Medical School, Boston, MA, USA, Tufts Medical School, Boston, MA, USA, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia, Burnet Institute, Melbourne, Victoria, Australia, Cluster Infectious Diseases, Public Health Service, Amsterdam, Netherlands and Department of Internal Medicine, Academic Medical Center, Center for Infection and Immunity, Amsterdam, Netherlands
    Int J Epidemiol 42:1649-59. 2013
    ..Potential collaborators should contact the InC(3) PI Dr Kimberley Page (kPage@psg.ucsf.edu) for further information. ..
  26. pmc Effective treatment of injecting drug users with recently acquired hepatitis C virus infection
    Gregory J Dore
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    Gastroenterology 138:123-35.e1-2. 2010
    ..We evaluated the efficacy of treatment of recent HCV infection in IDUs with acute and early chronic HCV...
  27. pmc Hepatitis C virus clearance, reinfection, and persistence, with insights from studies of injecting drug users: towards a vaccine
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia
    Lancet Infect Dis 12:408-14. 2012
    ....
  28. ncbi request reprint Protective immunity against hepatitis C virus infection
    Lisa N Elliot
    School of Women s and Children s Health, The University of New South Wales, Sydney, New South Wales, Australia
    Immunol Cell Biol 84:239-49. 2006
    ..This article reviews the evidence that the responses identified in this unique group of individuals represent the protective immunity that will need to be elicited by hepatitis C virus vaccines...
  29. doi request reprint Occult infection with hepatitis C virus: friend or foe?
    Peter B Sugden
    Inflammation and Infection Research Centre, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia
    Immunol Cell Biol 90:763-73. 2012
    ..Here we critically review the published literature, suggest further avenues of investigation and propose that occult infection may be beneficial to the host by maintaining immunological memory to protect against reinfection...
  30. doi request reprint A novel assay for detection of hepatitis C virus-specific effector CD4(+) T cells via co-expression of CD25 and CD134
    Elizabeth Keoshkerian
    Inflammation and Infection Research Centre, School of Medical Sciences, University of New South Wales, Sydney NSW, 2052, Australia
    J Immunol Methods 375:148-58. 2012
    ..Responses were highly correlated with those revealed by LPA. Application of this assay will further define the role of CD4(+) T cells in the immunopathogenesis of HCV infection...
  31. ncbi request reprint A phase I study of the pharmacokinetics and safety of passive immunotherapy with caprine anti-HIV antibodies, (PE)HRG214, in HIV-1-infected individuals
    Sarah L Pett
    HIV, Immunology and Infectious Diseases Clinical Services, St Vincent s Hospital, Sydney, and National Centre in HIV Epidemiology and Clinical Research, University of NSW, Darlinghurst, Sydney, Australia
    HIV Clin Trials 5:91-8. 2004
    ..To establish the pharmacokinetics and safety of single-dose polyclonal caprine anti-HIV antibodies ((PE)HRG214)in HIV-1-infected individuals...
  32. ncbi request reprint Eotaxin expression by epithelial cells and plasma cells in chronic asthma
    Rakesh K Kumar
    Inflammation Research Unit, Department of Pathology, University of New South Wales, Sydney, Australia
    Lab Invest 82:495-504. 2002
    ..Although high eotaxin levels alone are not sufficient to cause recruitment of eosinophils into the airways, recurrent exposure may generate or up-regulate additional signals required for eosinophil chemotaxis...
  33. pmc Quantification of hepatitis C virus in human liver and serum samples by using LightCycler reverse transcriptase PCR
    Peter A White
    Virology Division, Department of Microbiology, SEALS, Prince of Wales Hospital, Sydney, New South Wales 2031, Australia
    J Clin Microbiol 40:4346-8. 2002
    ..There was a strong correlation between hepatic and serum viral load measurements (r = 0.689, P = 0.004, n = 15), indicating that the level of viremia reflected the amount of virus present in the liver...
  34. doi request reprint The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C virus infection
    Jason Grebely
    The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia
    Hepatology 59:109-20. 2014
    ..Further research is required to elucidate the observed sex-based differences in HCV control. (Hepatology 2014;58:109-120). ..
  35. doi request reprint Next generation deep sequencing and vaccine design: today and tomorrow
    Fabio Luciani
    Inflammation and Infection Research Centre, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Trends Biotechnol 30:443-52. 2012
    ..NGS is unraveling the complex dynamics of viral evolution and host responses against these viruses, thus contributing substantially to the likelihood of successful vaccine development...
  36. ncbi request reprint Gene expression correlates of postinfective fatigue syndrome after infectious mononucleosis
    Barbara Cameron
    School of Medical Sciences, University of New South Wales, Sydney, Australia
    J Infect Dis 196:56-66. 2007
    ..Infectious mononucleosis (IM) commonly triggers a protracted postinfective fatigue syndrome (PIFS) of unknown pathogenesis...
  37. doi request reprint Differences in amniotic fluid and maternal serum cytokine levels in early midtrimester women without evidence of infection
    Sharon S W Chow
    School of Medical Sciences, University of New South Wales, 2052 NSW, Australia
    Cytokine 44:78-84. 2008
    ..This study provides new normative data for multiple cytokine levels in amniotic fluid and maternal sera at 14-16 weeks gestation, and is a valuable tool for future diagnostic and comparative studies...
  38. doi request reprint Neurocognitive disturbances associated with acute infectious mononucleosis, Ross River fever and Q fever: A preliminary investigation of inflammatory and genetic correlates
    Erin Cvejic
    School of Psychiatry, University of New South Wales, Australia
    Brain Behav Immun 36:207-14. 2014
    ..These associations require replication in a larger sample size. ..
  39. doi request reprint Mood disturbance after infection
    Pramudie Gunaratne
    1Inflammation and Infection Research Centre, School of Medical Sciences, University of New South Wales, Sydney, Australia
    Aust N Z J Psychiatry 47:1152-64. 2013
    ..This review aims to examine the evidence for such a link, specifically between acute, self-limiting infection and major depression, and to summarize the current understanding of pathophysiological mechanisms underlying this link...
  40. ncbi request reprint Cutting edge: vasoactive intestinal peptide acts as a potent suppressor of inflammation in vivo by trans-deactivating chemokine receptors
    Michael C Grimm
    Department of Medicine, St George Clinical School and Inflammation Research Unit, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia
    J Immunol 171:4990-4. 2003
    ..Circulating mononuclear cells from VIP-infused mice were unable to respond to chemokines. VIP may provide a novel approach to treatment of inflammatory diseases through inhibition of chemokine-dependent leukocyte recruitment...
  41. ncbi request reprint Regulation of MMPs and TIMPs by IL-1beta during corneal ulceration and infection
    Mei Lang Xue
    Cooperative Research Centre for Eye Research and Technology and Cornea and Contact Lens Research Unit, School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia
    Invest Ophthalmol Vis Sci 44:2020-5. 2003
    ..This study was conducted to investigate the role of IL-1beta in the regulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in a mouse model of experimental keratitis and corneal injury...
  42. ncbi request reprint Influences of distress and alcohol consumption on the development of a delayed-type hypersensitivity skin test response
    Alison J Smith
    School of Psychology, University of Western Sydney, Locked Bag 1797 Penrith South DC, NSW, 1797 Australia
    Psychosom Med 66:614-9. 2004
    ..These in vivo measures provide a biologically relevant assessment of cellular immune competence...
  43. ncbi request reprint Immunity against hepatitis C virus infection
    Jeffrey J Post
    Lancet 360:1020; author reply 1020-1. 2002
  44. ncbi request reprint To exercise or not to exercise in chronic fatigue syndrome? No longer a question
    Andrew R Lloyd
    Med J Aust 180:437-8. 2004