Jet Phey Lim
Affiliation: University of Melbourne
- A role for SNX5 in the regulation of macropinocytosisJet Phey Lim
Department of Biochemistry and Molecular Biology, The University of Melbourne, Melbourne, Victoria 3010, Australia
BMC Cell Biol 9:58. 2008..The mechanisms and components that regulate macropinocytosis are poorly understood. Here we have investigated the role of sorting nexin 5 (SNX5) in the regulation of macropinocytic activity...
- SNX5 is essential for efficient macropinocytosis and antigen processing in primary macrophagesJet Phey Lim
Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Victoria 3010, Australia
Biol Open 1:904-14. 2012..Therefore, SNX5 can function independently of SNX1 and is a modulator of macropinocytosis that influences the uptake and processing of soluble antigen in primary mouse macrophages...
- Macropinocytosis: an endocytic pathway for internalising large gulpsJet Phey Lim
Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, Victoria, Australia
Immunol Cell Biol 89:836-43. 2011..Here, we review the general characteristics of macropinocytosis, describe some of the regulators of this pathway, which have been identified to date and highlight strategies to explore the relevance of this endocytosis pathway in vivo...