Affiliation: University of Technology
- Zheng Y, Ji B, Song R, Wang S, Li T, Zhang X, et al. Accurate detection for a wide range of mutation and editing sites of microRNAs from small RNA high-throughput sequencing profiles. Nucleic Acids Res. 2016;44:e123 pubmed publisher..Compared with six existing studies or methods, MiRME has shown much superior performance for the identification and visualization of the M/E sites of miRNAs from the ever-increasing sRNA HTS profiles. ..
- Hasan M, Li J, Ahmad S, Molla M. predCar-site: Carbonylation sites prediction in proteins using support vector machine with resolving data imbalanced issue. Anal Biochem. 2017;525:107-113 pubmed publisher..A user-friendly web server of predCar-Site is available at http://research.ru.ac.bd/predCar-Site/. ..
- Ren J, Song J, Ellis J, Li J. Staged heterogeneity learning to identify conformational B-cell epitopes from antigen sequences. BMC Genomics. 2017;18:113 pubmed publisher..The proposed method uses only antigen sequence information, and thus has much broader applications. ..
- Peng H, Lan C, Zheng Y, Hutvagner G, Tao D, Li J. Cross disease analysis of co-functional microRNA pairs on a reconstructed network of disease-gene-microRNA tripartite. BMC Bioinformatics. 2017;18:193 pubmed publisher..We also confirmed that the regulation of the microRNAs for the development of cancers is more complex and have more unique properties than those of non-cancer diseases. ..
- Lan C, Chen Q, Li J. Grouping miRNAs of similar functions via weighted information content of gene ontology. BMC Bioinformatics. 2016;17:507 pubmed publisher..Our method has also demonstrated a novel usefulness for the function annotation of new miRNAs, as reported in the detailed case studies. ..
- Li Z, He Y, Liu Q, Zhao L, Wong L, Kwoh C, et al. Structural analysis on mutation residues and interfacial water molecules for human TIM disease understanding. BMC Bioinformatics. 2013;14 Suppl 16:S11 pubmed publisher..Our study reveals that a large cluster of water buried in protein interfaces is fragile and high-maintenance, closely related to the structure, function and evolution of the whole protein. ..