Jean Pierre Levesque

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. ncbi Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor
    J P Levesque
    Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia
    Blood 98:1289-97. 2001
  2. ncbi Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment
    Jean Pierre Levesque
    Stem Cell Biology Laboratory, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Exp Hematol 30:440-9. 2002
  3. ncbi A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29)
    Jean Pierre Levesque
    The Peter MacCallum Cancer Institute, Stem Cell Biology Laboratory, East Melbourne, Australia
    Hybrid Hybridomics 21:253-60. 2002
  4. ncbi Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
    Jean Pierre Levesque
    Stem Cell Biology Laboratory, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    J Clin Invest 111:187-96. 2003
  5. ncbi Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells
    Jean Pierre Levesque
    Stem Cell Laboratory, Peter MacCallum Cancer Institute, Locked Bag 1, A Beckett Street, Melbourne, Victoria 3000, Australia
    Exp Hematol 31:109-17. 2003
  6. ncbi Characterization of hematopoietic progenitor mobilization in protease-deficient mice
    Jean Pierre Levesque
    Stem Cell Biology Laboratory, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Blood 104:65-72. 2004
  7. ncbi Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1
    Ingrid G Winkler
    Adhesive Interactions and Cell Trafficking Laboratory, Peter MacCallum Cancer Centre, Melbourne, Vic, Australia
    Blood 103:1685-92. 2004
  8. ncbi Granulocyte colony-stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells
    Kirsten E Herbert
    Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
    Transplantation 83:375-84. 2007
  9. ncbi Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells
    Tetsuya Eto
    Cell Adhesion and Trafficking Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
    Exp Hematol 33:232-42. 2005
  10. ncbi The use of experimental murine models to assess novel agents of hematopoietic stem and progenitor cell mobilization
    Kirsten E Herbert
    Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
    Biol Blood Marrow Transplant 14:603-21. 2008

Detail Information

Publications10

  1. ncbi Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor
    J P Levesque
    Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia
    Blood 98:1289-97. 2001
    ....
  2. ncbi Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment
    Jean Pierre Levesque
    Stem Cell Biology Laboratory, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Exp Hematol 30:440-9. 2002
    ..We sought to determine whether mobilization induced by G-CSF or chemotherapy was triggered by common or distinct mechanisms...
  3. ncbi A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29)
    Jean Pierre Levesque
    The Peter MacCallum Cancer Institute, Stem Cell Biology Laboratory, East Melbourne, Australia
    Hybrid Hybridomics 21:253-60. 2002
    ..9H9 binding. Our data therefore suggest that the regulatory epitope of the human beta(1) integrin chain is flexible with multiple conformations according to the cationic environment...
  4. ncbi Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
    Jean Pierre Levesque
    Stem Cell Biology Laboratory, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    J Clin Invest 111:187-96. 2003
    ....
  5. ncbi Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells
    Jean Pierre Levesque
    Stem Cell Laboratory, Peter MacCallum Cancer Institute, Locked Bag 1, A Beckett Street, Melbourne, Victoria 3000, Australia
    Exp Hematol 31:109-17. 2003
    ..We sought to determine the mechanisms responsible for the reduced expression of c-KIT on mobilized hematopoietic progenitor cells...
  6. ncbi Characterization of hematopoietic progenitor mobilization in protease-deficient mice
    Jean Pierre Levesque
    Stem Cell Biology Laboratory, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Blood 104:65-72. 2004
    ..Collectively, these data suggest a complex model in which both protease-dependent and -independent pathways may contribute to HPC mobilization...
  7. ncbi Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1
    Ingrid G Winkler
    Adhesive Interactions and Cell Trafficking Laboratory, Peter MacCallum Cancer Centre, Melbourne, Vic, Australia
    Blood 103:1685-92. 2004
    ..These data demonstrate that an E-selectin ligand(s) other than PSGL-1 transduces growth inhibitory and proapoptotic signals and requires posttranslational fucosylation to be functional...
  8. ncbi Granulocyte colony-stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells
    Kirsten E Herbert
    Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
    Transplantation 83:375-84. 2007
    ....
  9. ncbi Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells
    Tetsuya Eto
    Cell Adhesion and Trafficking Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
    Exp Hematol 33:232-42. 2005
    ....
  10. ncbi The use of experimental murine models to assess novel agents of hematopoietic stem and progenitor cell mobilization
    Kirsten E Herbert
    Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
    Biol Blood Marrow Transplant 14:603-21. 2008
    ..Technical aspects regarding mobilization regimens and control arms, and choice of experimental animals are also discussed...