Research Topics
Species | Nicola T LautenschlagerSummaryAffiliation: University of Melbourne Country: Australia Publications
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Detail Information
Publications
Personality of mental healthcaregiversNicola T Lautenschlager
Academic Unit for Psychiatry of Old Age, St Vincent s Health, Department of Psychiatry, University of Melbourne, Melbourne, Australia
Curr Opin Psychiatry 26:97-101. 2013..This review investigated the recent evidence on the role of personality traits and features for caregiver burden and depression in caregivers of care recipients with mental illness...
Ginkgo biloba extract EGb 761® in the context of current developments in the diagnosis and treatment of age-related cognitive decline and Alzheimer's disease: a research perspectiveNicola T Lautenschlager
Academic Unit for Psychiatry of Old Age, St Vincent s Health, Department of Psychiatry, University of Melbourne, Melbourne, Australia
Int Psychogeriatr 24:S46-50. 2012....
The influence of exercise on brain aging and dementiaNicola T Lautenschlager
Academic Unit for Psychiatry of Old Age, St Vincent s Health, Department of Psychiatry, The University of Melbourne, St George s Hospital, 283 Cotham Road, Kew 3103, Victoria, Australia
Biochim Biophys Acta 1822:474-81. 2012..This article is part of a Special Issue entitled: Imaging Brain Aging and Neurodegenerative disease...
Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trialNicola T Lautenschlager
WA Centre for Health and Ageing, University of Western Australia, Melbourne, Australia
JAMA 300:1027-37. 2008..Many observational studies have shown that physical activity reduces the risk of cognitive decline; however, evidence from randomized trials is lacking...
Physical activity and mild cognitive impairment and Alzheimer's diseaseNicola T Lautenschlager
Academic Unit for Psychiatry of Old Age, St Vincent s Health, Department of Psychiatry, St George s Hospital, The University of Melbourne, 283 Cotham Road, Kew, 3103, Victoria, Australia
Curr Neurol Neurosci Rep 10:352-8. 2010..The first large-scale multidomain intervention trials are under way to put this to the test. This review aims to give an overview of recent trials of physical activity in patients with MCI or dementia...
The PACE study: a randomised clinical trial of cognitive activity (CA) for older adults with mild cognitive impairment (MCI)Mandy R Vidovich
Western Australia Centre for Health and Ageing, School of Psychiatry and Clinical Neurosciences, Perth, Western Australia, Australia
Trials 10:114. 2009..The Promoting Healthy Ageing with Cognitive Exercise (PACE) study has been designed to determine whether a cognitive activity intervention decreases the rate of cognitive decline amongst older adults with mild cognitive impairment (MCI)...
Current experiences and educational preferences of general practitioners and staff caring for people with dementia living in residential facilitiesChristopher Beer
Western Australian Centre for Health and Ageing, Western Australian Institute for Medical Research, Perth, Australia
BMC Geriatr 9:36. 2009..We sought to determine participation in dementia education, perceived levels of current knowledge regarding dementia, perceived unmet educational needs, current barriers, facilitators and preferences for dementia education...
Effectiveness of balance training exercise in people with mild to moderate severity Alzheimer's disease: protocol for a randomised trialKeith D Hill
Musculoskeletal Research Centre, Faculty of Health Sciences, La Trobe University, Bundoora, Victoria, 3086 Australia
BMC Geriatr 9:29. 2009..The primary objective of this study is to evaluate whether a home-based balance exercise programme improves balance performance in people with mild to moderate severity Alzheimer's disease...
Anxiety, depression, and comorbid anxiety and depression: risk factors and outcome over two yearsOsvaldo P Almeida
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Perth, WA, Australia
Int Psychogeriatr 24:1622-32. 2012..This study aimed to determine: (1) the prevalence of depression, anxiety, and depression associated with anxiety (DA); (2) the risk factor profile of depression, anxiety, and DA; (3) the course of depression, anxiety, and DA over 24 months...
Factors associated with suicidal thoughts in a large community study of older adultsOsvaldo P Almeida
Western Australia Centre for Health and Ageing M573, University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
Br J Psychiatry 201:466-72. 2012..Thoughts about death and self-harm in old age have been commonly associated with the presence of depression, but other risk factors may also be important...
A randomized trial to reduce the prevalence of depression and self-harm behavior in older primary care patientsOsvaldo P Almeida
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Australia
Ann Fam Med 10:347-56. 2012..We wanted to determine whether an educational intervention targeting general practitioners reduces the 2-year prevalence of depression and self-harm behavior among their older patients...
Dementia in residential care: education intervention trial (DIRECT); protocol for a randomised controlled trialChristopher D Beer
WA Centre for Health and Ageing, Centre for Medical Research, Perth, Western Australia, Australia
Trials 11:63. 2010..The DIRECT study will determine if delivery of education to General Practitioners (GPs) and care staff improves the quality of life of residential care recipients with cognitive impairment...
Two-year course of cognitive function and mood in adults with congestive heart failure and coronary artery disease: the Heart-Mind StudyOsvaldo P Almeida
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Australia
Int Psychogeriatr 24:38-47. 2012..We designed this study to determine if adults with CHF show evidence of cognitive decline compared with adults with and without coronary artery disease (CAD)...
A cluster-randomised trial of staff education to improve the quality of life of people with dementia living in residential care: the DIRECT studyChristopher Beer
WA Centre for Health and Ageing, Centre for Medical Research, Perth, Western Australia, Australia
PLoS ONE 6:e28155. 2011....
Subjective memory complaints with and without objective memory impairment: relationship with risk factors for dementiaNicola T Lautenschlager
School of Psychiatry and Clinical Neurosciences, University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
Am J Geriatr Psychiatry 13:731-4. 2005....
Olfactory dysfunction is associated with subjective memory complaints in community-dwelling elderly individualsHamid R Sohrabi
The School of Psychiatry and Clinical Neuroscience, University of Western Australia, Crawley, WA, Australia
J Alzheimers Dis 17:135-42. 2009....
'Gotta be sit down and worked out together': views of Aboriginal caregivers and service providers on ways to improve dementia care for Aboriginal AustraliansKate Smith
WA Centre for Health and Ageing, University of WA, Perth, Western Australia, Australia
Rural Remote Health 11:1650. 2011..The objective of this study was to determine ways to overcome factors affecting the successful delivery of services to Aboriginal people with dementia living in remote communities, and to their families and communities...
Awareness of cognitive deficits in older adults with cognitive-impairment-no-dementia (CIND): comparison with informant reportKathryn R Greenop
Division of Population Sciences, Telethon Institute for Child Health Research, Center for Child Health Research, University of Western Australia, Subiaco, WA, Australia
Alzheimer Dis Assoc Disord 25:24-33. 2011..In addition, self-report of cognitive complaints may be at least as useful as informant report when screening community-dwelling older adults at risk of cognitive decline and dementia...
24-month effect of smoking cessation on cognitive function and brain structure in later lifeOsvaldo P Almeida
Western Australian Centre for Health and Ageing, Centre for Medical Research, University of Western Australia, Crawley, Perth, WA, Australia
Neuroimage 55:1480-9. 2011..We completed this trial to determine if smoking cessation decreases the progression of cognitive decline in later life...
The fitness for the Ageing Brain Study II (FABS II): protocol for a randomized controlled clinical trial evaluating the effect of physical activity on cognitive function in patients with Alzheimer's diseaseElizabeth V Cyarto
National Ageing Research Institute, Melbourne, Australia
Trials 11:120. 2010..This paper describes the background, objectives of the study, and an overview of the protocol including design, organization and data collection methods...
Factors associated with dementia in Aboriginal AustraliansKate Smith
Western Australian Centre for Health and Ageing M570, Centre for Health Research, University of Western Australia, 35 Stirling Highway, Crawley, Perth, Western Australia 6009, Australia
Aust N Z J Psychiatry 44:888-93. 2010..This study was designed to determine the demographic, lifestyle and clinical factors associated with dementia in Aboriginal Australians living in the Kimberley region of Western Australia...
Socioeconomic disadvantage increases risk of prevalent and persistent depression in later lifeOsvaldo P Almeida
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, WA, Australia
J Affect Disord 138:322-31. 2012..This study aimed to determine the independent association between socioeconomic disadvantage and depression...
The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's diseaseKathryn A Ellis
Academic Unit for Psychiatry of Old Age, Department of Psychiatry, The University of Melbourne, St Vincent s Aged Psychiatry Service, St George s Hospital, Victoria, Australia
Int Psychogeriatr 21:672-87. 2009..This paper describes the recruitment of the cohort and gives information about the study methodology, baseline demography, diagnoses, medical comorbidities, medication use, and cognitive function of the participants...
Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later lifeOsvaldo P Almeida
School of Psychiatry and Clinical Neurosciences, University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
Neurobiol Aging 26:251-7. 2005..These results indicate that, in isolation, the MTHFR C677T gene variation does not play an important role in the modulation of mood and cognitive performance in later life...
Dietary patterns are associated with cognition among older people with mild cognitive impairmentSusan J Torres
Centre for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Burwood 3125, Victoria, Australia
Nutrients 4:1542-51. 2012..55; 95% CI: 1.08-6.03); as assessed by the Cambridge Cognitive Examination. In a group of older people with MCI; a diet high in processed foods was associated with some level of cognitive impairment...
Homocysteine, grey matter and cognitive function in adults with cardiovascular diseaseAndrew H Ford
Western Australian Centre for Health and Ageing, University of Western Australia, Perth, Western Australia, Australia
PLoS ONE 7:e33345. 2012..Elevated total plasma homocysteine (tHcy) has been associated with cognitive impairment, vascular disease and brain atrophy...
Balance and mobility dysfunction and falls risk in older people with mild to moderate Alzheimer diseasePlaiwan Suttanon
Department of Physiotherapy, La Trobe University, Bundoora, Victoria, Australia
Am J Phys Med Rehabil 91:12-23. 2012..This study aimed to identify the magnitude and type of balance and mobility impairments in people with Alzheimer disease by comparing their performance with that of older people without cognitive impairment...
Healthy mental ageingLeon Flicker
Department of Geriatric Medicine, School of Medicine and Pharmacology, University of Western Australia, Australia
J Br Menopause Soc 12:92-6. 2006....
Premorbid personality traits are associated with post-stroke behavioral and psychological symptoms: a three-month follow-up study in Perth, Western AustraliaKathryn R Greenop
WA Centre for Health and Ageing, University of Western Australia, Perth, Australia
Int Psychogeriatr 21:1063-71. 2009..This study sought to investigate further the relationship between premorbid personality and a number of common post-stroke behavioral and psychological symptoms in a three-month follow-up study...
The relationship between memory complaints, perceived quality of life and mental health in apolipoprotein Eepsilon4 carriers and non-carriersHamid R Sohrabi
The School of Psychiatry and Clinical Neuroscience, University of Western Australia, WA, Australia
J Alzheimers Dis 17:69-79. 2009....
Cognitive and brain changes associated with ischaemic heart disease and heart failureOsvaldo P Almeida
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Perth, Australia
Eur Heart J 33:1769-76. 2012..This study aimed to determine whether, compared with controls with and without IHD, adults with systolic HF show evidence of cognitive impairment and cerebral grey matter (GM) loss...
Personality change in old ageNicola T Lautenschlager
School of Psychiatry and Clinical Neurosciences and WA Centre for Health and Ageing, University of Western Australia, Australia
Curr Opin Psychiatry 20:62-6. 2007..The present short review summarizes some of the most important personality changes in older adults...
Effectiveness of a smoking cessation intervention in older adultsRobert J Tait
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
Addiction 102:148-55. 2007....
Smoking is associated with reduced cortical regional gray matter density in brain regions associated with incipient Alzheimer diseaseOsvaldo P Almeida
Western Australia Centre for Health and Ageing, School of Psychiatry and Clinical Neurosciences, University of Western Australia, 35 Stirling Highway, Perth, Western Australia 6009, Australia
Am J Geriatr Psychiatry 16:92-8. 2008..The authors designed this study to determine if older people who smoke have decreased gray matter density in brain regions associated with incipient AD...
Factors associated with self and informant ratings of the quality of life of people with dementia living in care facilities: a cross sectional studyChristopher Beer
WA Centre for Health and Ageing, Centre for Medical Research, Perth, Western Australia, Australia
PLoS ONE 5:e15621. 2010..We undertook the present study to describe and determine the factors associated with ratings of the quality of life of a cohort of people with dementia living in a residential care facility...
Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer's disease: a pilot randomized controlled trialPlaiwan Suttanon
1School of Physiotherapy, Faculty of Health Sciences, La Trobe University, Bundoora, Victoria, Australia
Clin Rehabil 27:427-38. 2013..Conclusions: The exercise programme was feasible and safe and may help improve balance and mobility performance and reduce falls risk in people with Alzheimer's disease...
Physical activity and cognition in old ageNicola T Lautenschlager
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia
Curr Opin Psychiatry 19:190-3. 2006..This paper critically reviews the evidence in support of the association between exercise and cognitive decline/dementia, as reported by cohort studies or clinical trials...
Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: the AIBL Active trialElizabeth V Cyarto
National Ageing Research Institute, Melbourne, Australia
BMC Psychiatry 12:167. 2012..The aim of AIBL Active is to determine whether a 24-month physical activity program can delay the progression of white matter changes on magnetic resonance imaging (MRI)...
Recruiting and retaining GPs and patients in intervention studies: the DEPS-GP project as a case studyMichelle K Williamson
Centre for Health Policy, Programs and Economics, School of Population Health, University of Melbourne, Australia
BMC Med Res Methodol 7:42. 2007..The paper aims to outline experiences that may be of interest to others considering engaging GPs and/or their patients in primary care studies...
Dementia associated with infectious diseasesOsvaldo P Almeida
University of Western Australia, School of Psychiatry and Clinical Neurosciences, Mail Delivery Point M573, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
Int Psychogeriatr 17:S65-77. 2005....
Treatment fidelity and acceptability of a cognition-focused intervention for older adults with mild cognitive impairment (MCI)Mandy R Vidovich
Western Australia Centre for Health and Ageing, CMR, WAIMR, University of Western Australia, Perth, Western Australia, Australia
Int Psychogeriatr 25:815-23. 2013..Acceptability and fidelity assessments are an integral part of research, although few published trials comment on these processes in detail...
Common versus uncommon causes of dementiaNicola T Lautenschlager
University of Western Australia, School of Psychiatry and Clinical Neurosciences, Mail Delivery Point M573, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
Int Psychogeriatr 17:S27-34. 2005....
Dementia associated with alcohol and other drug useGary K Hulse
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
Int Psychogeriatr 17:S109-27. 2005..Health promotion programs designed to decrease tobacco smoking and "harmful" alcohol use (and possibly other drug use) may decrease the burden of cognitive impairment and perhaps dementia in later life...
Association between lifestyle factors and mental health measures among community-dwelling older womenKellie Cassidy
School of Psychiatry, and Clinical Neurosciences, University of Western Australia, Perth, Australia
Aust N Z J Psychiatry 38:940-7. 2004..Randomised clinical trials should be now designed to clarify whether management of lifestyle factors reduces the incidence of mood disorders and cognitive impairment in later life...
