R G Langham

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. ncbi request reprint Over-expression of platelet-derived growth factor in human diabetic nephropathy
    Robyn G Langham
    University of Melbourne St Vincent s Hospital Department of Medicine, Fitzroy, Australia
    Nephrol Dial Transplant 18:1392-6. 2003
  2. doi request reprint Urotensin II and the kidney
    Robyn G Langham
    University of Melbourne, Department of Medicine, St Vincent s Hospital, Fitzroy, Victoria, Australia
    Curr Opin Nephrol Hypertens 22:107-12. 2013
  3. doi request reprint Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control
    R G Langham
    University of Melbourne Department of Medicine, St Vincent s Hospital, Fitzroy, Vic, Australia
    Diabetologia 51:668-74. 2008
  4. ncbi request reprint Increased expression of urotensin II and urotensin II receptor in human diabetic nephropathy
    Robyn G Langham
    University of Melbourne Department of Medicine, St Vincent s Hospital, Fitzroy, Victoria, Australia
    Am J Kidney Dis 44:826-31. 2004
  5. ncbi request reprint Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition
    Robyn G Langham
    University of Melbourne, Department of Medicine, St Vincent s Hospital, Australia
    Diabetes Care 29:2670-5. 2006
  6. ncbi request reprint Dysregulated growth factor gene expression is associated with tubulointerstitial apoptosis and renal dysfunction
    S A Teteris
    Department of Medicine, Central and Eastern Clinical School, Monash University, Prahran, Victoria, Australia
    Kidney Int 71:1044-53. 2007
  7. ncbi request reprint Transforming growth factor-beta1 and tumor growth factor-beta-inducible gene-H3 in nonrenal transplant cyclosporine nephropathy
    R G Langham
    Monash University, Department of Medicine, Prahran, Melbourne, Vic, Australia 3181
    Transplantation 72:1826-9. 2001
  8. ncbi request reprint Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: effects of angiotensin converting enzyme inhibition
    R G Langham
    University of Melbourne Department of Medicine, St Vincent s Hospital, Fitzroy, Victoria, Australia
    Diabetologia 45:1572-6. 2002
  9. ncbi request reprint Urinary connective tissue growth factor excretion in patients with type 1 diabetes and nephropathy
    Richard E Gilbert
    Department of Medicine, St Vincent s Hospital, University of Melbourne, Fitzroy, Australia
    Diabetes Care 26:2632-6. 2003
  10. doi request reprint Perindopril attenuates tubular hypoxia and inflammation in an experimental model of diabetic nephropathy in transgenic Ren-2 rats
    Kathryn J Wiggins
    Department of Medicine, The University of Melbourne, St Vincent s Hospital, Melbourne, Victoria, Australia
    Nephrology (Carlton) 13:721-9. 2008

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Over-expression of platelet-derived growth factor in human diabetic nephropathy
    Robyn G Langham
    University of Melbourne St Vincent s Hospital Department of Medicine, Fitzroy, Australia
    Nephrol Dial Transplant 18:1392-6. 2003
    ..In this study, the gene expression and protein distribution of platelet-derived growth factor-A and -B (PDGF-A and PDGF-B) in human diabetic nephropathy were examined...
  2. doi request reprint Urotensin II and the kidney
    Robyn G Langham
    University of Melbourne, Department of Medicine, St Vincent s Hospital, Fitzroy, Victoria, Australia
    Curr Opin Nephrol Hypertens 22:107-12. 2013
    ....
  3. doi request reprint Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control
    R G Langham
    University of Melbourne Department of Medicine, St Vincent s Hospital, Fitzroy, Vic, Australia
    Diabetologia 51:668-74. 2008
    ..We sought to determine whether in addition to activation, diabetes may lead to increased transcription of two PKC isoforms that have been implicated in the pathogenesis of diabetic nephropathy, PKC-alpha and PKC-beta...
  4. ncbi request reprint Increased expression of urotensin II and urotensin II receptor in human diabetic nephropathy
    Robyn G Langham
    University of Melbourne Department of Medicine, St Vincent s Hospital, Fitzroy, Victoria, Australia
    Am J Kidney Dis 44:826-31. 2004
    ..Accordingly, the present study sought to examine the expression and localization of UII and its receptor in kidney tissue from patients with diabetic nephropathy...
  5. ncbi request reprint Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition
    Robyn G Langham
    University of Melbourne, Department of Medicine, St Vincent s Hospital, Australia
    Diabetes Care 29:2670-5. 2006
    ..However, the role of the RAS blockade in abrogating TGF-beta in human disease is unknown. Accordingly, we sought to examine TGF-beta gene expression and biological activity in human renal biopsies, before and after ACE inhibition...
  6. ncbi request reprint Dysregulated growth factor gene expression is associated with tubulointerstitial apoptosis and renal dysfunction
    S A Teteris
    Department of Medicine, Central and Eastern Clinical School, Monash University, Prahran, Victoria, Australia
    Kidney Int 71:1044-53. 2007
    ..005). Therefore dysregulation of cytokine/growth factor expression plays a central role in the progression of chronic renal disease through contribution to renal cell loss, tubulointerstitial injury, and renal dysfunction...
  7. ncbi request reprint Transforming growth factor-beta1 and tumor growth factor-beta-inducible gene-H3 in nonrenal transplant cyclosporine nephropathy
    R G Langham
    Monash University, Department of Medicine, Prahran, Melbourne, Vic, Australia 3181
    Transplantation 72:1826-9. 2001
    ..05). These findings support the hypothesis that TGF-beta1 is an important cytokine in the development of CyAN, independent of its role in chronic rejection in renal allografts...
  8. ncbi request reprint Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: effects of angiotensin converting enzyme inhibition
    R G Langham
    University of Melbourne Department of Medicine, St Vincent s Hospital, Fitzroy, Victoria, Australia
    Diabetologia 45:1572-6. 2002
    ....
  9. ncbi request reprint Urinary connective tissue growth factor excretion in patients with type 1 diabetes and nephropathy
    Richard E Gilbert
    Department of Medicine, St Vincent s Hospital, University of Melbourne, Fitzroy, Australia
    Diabetes Care 26:2632-6. 2003
    ..In this cross-sectional study, we sought to examine the urinary excretion of the profibrotic cytokine connective tissue growth factor (CTGF) in type 1 diabetic patients with incipient and overt diabetic nephropathy...
  10. doi request reprint Perindopril attenuates tubular hypoxia and inflammation in an experimental model of diabetic nephropathy in transgenic Ren-2 rats
    Kathryn J Wiggins
    Department of Medicine, The University of Melbourne, St Vincent s Hospital, Melbourne, Victoria, Australia
    Nephrology (Carlton) 13:721-9. 2008
    ..In this study the localization of cellular hypoxia in an experimental model of diabetic nephropathy was assessed, and the effect of the angiotensin-converting enzyme inhibitor perindopril on hypoxia evaluated...
  11. ncbi request reprint Vasoactive renal factors and the progression of diabetic nephropathy
    Lesley Wassef
    University of Melbourne, Department of Medicine, St Vincent s Hospital, Victoria 3165, Australia
    Curr Pharm Des 10:3373-84. 2004
    ..Further investigation into the effects of inhibiting vasoactive compounds, including endothelin, urotensin II and vasopeptidases, together with inhibiting RAS, may provide another therapeutic avenue for treating diabetic nephropathy...
  12. pmc Renal primary cilia lengthen after acute tubular necrosis
    Elizabeth Verghese
    Monash Immunology and Stem Cell Laboratories, Monash University, Melbourne, Victoria, Australia
    J Am Soc Nephrol 20:2147-53. 2009
    ..These findings demonstrate that the length of renal cilia is a clinically relevant indicator of renal injury and repair...
  13. ncbi request reprint Expression of filtrin in human glomerular diseases
    Pekka Ihalmo
    Department of Bacteriology and Immunology, Haartman Institute, Biomedicum Helsinki, University of Helsinki, Finland, and Renal Immunopathology Laboratory, Fondazione D Amico per la Ricerca sulle Malattie Renali, San Carlo Borromeo Hospital, Milan, Italy
    Nephrol Dial Transplant 22:1903-9. 2007
    ..In this study, the gene and protein expression of filtrin were examined in patients with acquired proteinuric diseases...
  14. doi request reprint Towards standard protocols and guidelines for urine proteomics: a report on the Human Kidney and Urine Proteome Project (HKUPP) symposium and workshop, 6 October 2007, Seoul, Korea and 1 November 2007, San Francisco, CA, USA
    Tadashi Yamamoto
    Department of Structural Pathology, Institute of Nephrology, Graduate School of Medical and Dental Sciences, Niigata, Japan
    Proteomics 8:2156-9. 2008
    ..An initial draft of standard protocols and guidelines for proteome analysis of non-proteinuric urine (urine protein excretion < or =150 mg/day) will soon be released as the first HKUPP product...
  15. ncbi request reprint Diabetic nephropathy without the diabetes: if not hyperglycaemia, then what?
    Robyn G Langham
    Nephrology (Carlton) 12:67-8. 2007