Jim Lagopoulos

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi request reprint A functional magnetic resonance imaging study of emotional Stroop in euthymic bipolar disorder
    Jim Lagopoulos
    CADE Clinic, Royal North Shore Hospital, The University of Sydney, Sydney, Australia
    Neuroreport 18:1583-7. 2007
  2. doi request reprint Increased theta and alpha EEG activity during nondirective meditation
    Jim Lagopoulos
    Discipline of Psychological Medicine and Northern Clinical School, University of Sydney, Sydney, New South Wales, Australia
    J Altern Complement Med 15:1187-92. 2009
  3. pmc An event-related functional MRI study of working memory in euthymic bipolar disorder
    Jim Lagopoulos
    Psychological Medicine Northern Clinical School, University of Sydney, Sydney, Australia
    J Psychiatry Neurosci 32:174-84. 2007
  4. pmc Mismatch negativity/P3a complex in young people with psychiatric disorders: a cluster analysis
    Manreena Kaur
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    PLoS ONE 7:e51871. 2012
  5. pmc Neurophysiological biomarkers support bipolar-spectrum disorders within psychosis cluster
    Manreena Kaur
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    J Psychiatry Neurosci 37:313-21. 2012
  6. doi request reprint Delayed early face processing in bipolar disorder
    Racheal Degabriele
    School of Psychiatry, University of New South Wales, Sydney, NSW, Australia
    Neuroreport 23:152-6. 2012
  7. doi request reprint A functional MRI study of Theory of Mind in euthymic bipolar disorder patients
    Gin S Malhi
    Discipline of Psychological Medicine, University of Sydney, CADE Clinic, Department of Academic Psychiatry, Level 5, Building 36, Royal North Shore Hospital, St Leonards, Sydney, NSW 2065, Australia
    Bipolar Disord 10:943-56. 2008
  8. ncbi request reprint Reduced activation to implicit affect induction in euthymic bipolar patients: an fMRI study
    Gin S Malhi
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Affect Disord 97:109-22. 2007
  9. doi request reprint Glutathione relates to neuropsychological functioning in mild cognitive impairment
    Shantel L Duffy
    Ageing Brain Centre, Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia
    Alzheimers Dement 10:67-75. 2014
  10. doi request reprint Distinguishing young people with emerging bipolar disorders from those with unipolar depression
    Elizabeth M Scott
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, 100 Mallet Street, Camperdown, NSW 2050, Australia
    J Affect Disord 144:208-15. 2013

Detail Information

Publications51

  1. ncbi request reprint A functional magnetic resonance imaging study of emotional Stroop in euthymic bipolar disorder
    Jim Lagopoulos
    CADE Clinic, Royal North Shore Hospital, The University of Sydney, Sydney, Australia
    Neuroreport 18:1583-7. 2007
    ..This study provides evidence for a disconnection in the transfer of information within frontostriatal networks in bipolar disorder...
  2. doi request reprint Increased theta and alpha EEG activity during nondirective meditation
    Jim Lagopoulos
    Discipline of Psychological Medicine and Northern Clinical School, University of Sydney, Sydney, New South Wales, Australia
    J Altern Complement Med 15:1187-92. 2009
    ....
  3. pmc An event-related functional MRI study of working memory in euthymic bipolar disorder
    Jim Lagopoulos
    Psychological Medicine Northern Clinical School, University of Sydney, Sydney, Australia
    J Psychiatry Neurosci 32:174-84. 2007
    ..In this study, we investigated the encode, delay and response components of WM to identify the neural substrates and respective contributions to the WM deficits found in BD...
  4. pmc Mismatch negativity/P3a complex in young people with psychiatric disorders: a cluster analysis
    Manreena Kaur
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    PLoS ONE 7:e51871. 2012
    ..A data driven approach may help to further elucidate novel patterns of MMN/P3a amplitudes that characterise distinct subgroups in patients with emerging psychiatric disorders...
  5. pmc Neurophysiological biomarkers support bipolar-spectrum disorders within psychosis cluster
    Manreena Kaur
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    J Psychiatry Neurosci 37:313-21. 2012
    ..Further research is warranted to determine whether patients with bipolar-spectrum disorders show similar impairments in these biomarkers...
  6. doi request reprint Delayed early face processing in bipolar disorder
    Racheal Degabriele
    School of Psychiatry, University of New South Wales, Sydney, NSW, Australia
    Neuroreport 23:152-6. 2012
    ..Delayed neural responses may be an ERP correlate of white matter deficits that have previously been identified. Furthermore, implications for early visual impairments may involve behavioural symptoms downstream...
  7. doi request reprint A functional MRI study of Theory of Mind in euthymic bipolar disorder patients
    Gin S Malhi
    Discipline of Psychological Medicine, University of Sydney, CADE Clinic, Department of Academic Psychiatry, Level 5, Building 36, Royal North Shore Hospital, St Leonards, Sydney, NSW 2065, Australia
    Bipolar Disord 10:943-56. 2008
    ..To determine the neural responses invoked in Theory of Mind (ToM) in euthymic bipolar patients as compared with healthy subjects...
  8. ncbi request reprint Reduced activation to implicit affect induction in euthymic bipolar patients: an fMRI study
    Gin S Malhi
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Affect Disord 97:109-22. 2007
    ..To examine whether euthymic bipolar patients engage similar or contrasting brain regions as healthy subjects when responding to implicit affect induction...
  9. doi request reprint Glutathione relates to neuropsychological functioning in mild cognitive impairment
    Shantel L Duffy
    Ageing Brain Centre, Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia
    Alzheimers Dement 10:67-75. 2014
    ..This study aims to assess in vivo levels of glutathione via proton magnetic resonance spectroscopy in patients with MCI and to determine how glutathione relates to cognitive decline...
  10. doi request reprint Distinguishing young people with emerging bipolar disorders from those with unipolar depression
    Elizabeth M Scott
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, 100 Mallet Street, Camperdown, NSW 2050, Australia
    J Affect Disord 144:208-15. 2013
    ..To facilitate early intervention, there is a need to distinguish unipolar versus bipolar illness trajectories in adolescents and young adults with adult-type mood disorders...
  11. pmc Correlating anterior insula gray matter volume changes in young people with clinical and neurocognitive outcomes: an MRI study
    Sean N Hatton
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    BMC Psychiatry 12:45. 2012
    ..This study examined the relationship between anterior insula GMV, clinical symptom severity and neuropsychological performance in a heterogeneous cohort of young people presenting for mental health care...
  12. ncbi request reprint Is a lack of disgust something to fear? A functional magnetic resonance imaging facial emotion recognition study in euthymic bipolar disorder patients
    Gin S Malhi
    CADE Clinic, Royal North Shore Hospital, University of Sydney, Australia
    Bipolar Disord 9:345-57. 2007
    ..To determine the neural responses invoked in the recognition of facial fear and disgust in euthymic bipolar patients as compared with healthy subjects...
  13. ncbi request reprint Cognitive generation of affect in hypomania: an fMRI study
    Gin S Malhi
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Bipolar Disord 6:271-85. 2004
    ..To identify the brain regions associated with the cognitive generation of affect in hypomanic bipolar patients...
  14. doi request reprint Longitudinal associations between mismatch negativity and disability in early schizophrenia- and affective-spectrum disorders
    Manreena Kaur
    Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Sydney, Australia Electronic address
    Prog Neuropsychopharmacol Biol Psychiatry 46:161-9. 2013
    ....
  15. doi request reprint A double-blind, sham-controlled trial of transcranial direct current stimulation for the treatment of depression
    Colleen K Loo
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Int J Neuropsychopharmacol 13:61-9. 2010
    ..It is recommended that the efficacy of tDCS in depression be further evaluated over a longer treatment period, using enhanced stimulation parameters...
  16. doi request reprint Fronto-striatal correlates of impaired implicit sequence learning in major depression: an fMRI study
    Sharon L Naismith
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia
    J Affect Disord 125:256-61. 2010
    ..This study sought to probe the integrity of fronto-striatal circuits using functional magnetic resonance imaging (fMRI) in conjunction with a theoretically-driven motor sequencing implicit learning (IL) task...
  17. doi request reprint Cognitive dysfunction and functional disability in alcohol-dependent adults with or without a comorbid affective disorder
    Rico S C Lee
    a Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Cogn Neuropsychiatry 20:222-31. 2015
    ..We investigated the neuropsychology of alcohol dependence in detoxified adults with and without affective comorbidity and examined the factors associated with prolonged functional disability...
  18. doi request reprint Risky alcohol use in young persons with emerging bipolar disorder is associated with increased oxidative stress
    Kate M Chitty
    Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Sydney, NSW 2050, Australia
    J Affect Disord 150:1238-41. 2013
    ..Proton magnetic resonance spectroscopy ((1)H-MRS) is an in vivo tissue-based imaging modality that allows the investigation of changes in the brains primary antioxidant, glutathione (GSH), as a result of alcohol use in this population...
  19. pmc Microstructural white matter changes in the corpus callosum of young people with Bipolar Disorder: a diffusion tensor imaging study
    Jim Lagopoulos
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, Australia
    PLoS ONE 8:e59108. 2013
    ..Our findings provide evidence of microstructural white matter changes early in the course of illness within the corpus callosum and the nature of these changes suggest they are associated with abnormalities in the myelination of axons...
  20. doi request reprint Mentalizing impairment in schizophrenia: a functional MRI study
    Pritha Das
    Discipline of Psychiatry, Sydney Medical School, University of Sydney, NSW 2065, Australia
    Schizophr Res 134:158-64. 2012
    ..Therefore in the present study we used functional neuroimaging and a task that elicits 'on-line' mentalizing to investigate the neural basis of ToM deficits in schizophrenia...
  21. ncbi request reprint An emotional Stroop functional MRI study of euthymic bipolar disorder
    Gin S Malhi
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Bipolar Disord 7:58-69. 2005
    ..To identify the brain regions associated with emotional processing in euthymic bipolar patients...
  22. doi request reprint Neural correlates of emotional face processing in bipolar disorder: an event-related potential study
    Racheal Degabriele
    School of Psychiatry, The University of New South Wales, Sydney, Australia
    J Affect Disord 133:212-20. 2011
    ..The aim of our study was to explore these processes as indexed by the face-specific P100 and N170 ERP components in a BD cohort...
  23. pmc Delayed circadian phase is linked to glutamatergic functions in young people with affective disorders: a proton magnetic resonance spectroscopy study
    Sharon L Naismith
    Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Camperdown, NSW, 2050, Australia
    BMC Psychiatry 14:345. 2014
    ....
  24. pmc Frontal lobe changes occur early in the course of affective disorders in young people
    Jim Lagopoulos
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    BMC Psychiatry 12:4. 2012
    ..Contrasts were carried out between controls subjects and patients cohorts with attenuated syndromes and discrete disorders, separately...
  25. pmc Short association fibres of the insula-temporoparietal junction in early psychosis: a diffusion tensor imaging study
    Sean N Hatton
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, NSW, Australia
    PLoS ONE 9:e112842. 2014
    ....
  26. ncbi request reprint Cognitive generation of affect in bipolar depression: an fMRI study
    Gin S Malhi
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Eur J Neurosci 19:741-54. 2004
    ..The differential patterns of activation inform us about bipolar depression and have potential diagnostic and therapeutic significance...
  27. doi request reprint Hippocampal volume in older adults at risk of cognitive decline: the role of sleep, vascular risk, and depression
    Emma L Elcombe
    Healthy Brain Ageing Program, University of Sydney, NSW, Australia
    J Alzheimers Dis 44:1279-90. 2015
    ..This study aimed to examine the relationship between modifiable risk factors and hippocampal volume in older adults at risk of cognitive decline...
  28. pmc White matter tractography in early psychosis: clinical and neurocognitive associations
    Sean N Hatton
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, NSW, Australia
    J Psychiatry Neurosci 39:417-27. 2014
    ..Using whole tract reconstruction techniques, the aim of this study was to identify the white matter pathology associated with the common clinical symptoms and executive function impairments observed in young people with psychosis...
  29. doi request reprint Emotional processing, p50 sensory gating, and social functioning in bipolar disorder
    Laura Vuillier
    Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Sydney, Australia Department of Psychology and Faculty of Education, University of Cambridge, Cambridge, United Kingdom
    Clin EEG Neurosci 46:81-7. 2015
    ..Thus, it appears that patients with the greatest impairment in sensory gating also have the most difficulty engaging in social situations. ..
  30. doi request reprint Oxidative stress and depressive symptoms in older adults: A magnetic resonance spectroscopy study
    Shantel L Duffy
    Healthy Brain Ageing Program Brain and Mind Research Institute, The University of Sydney, 94 Mallett Street, Camperdown, NSW 2050, Australia Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, 94 Mallett Street, Camperdown, NSW 2050, Australia Electronic address
    J Affect Disord 180:29-35. 2015
    ..Further research examining the utility of glutathione as a marker for depressive symptoms and cognitive decline is now required. ..
  31. pmc Deficits in episodic memory retrieval reveal impaired default mode network connectivity in amnestic mild cognitive impairment
    Cameron J Dunn
    Healthy Brain Ageing Program, Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, NSW, Australia
    Neuroimage Clin 4:473-80. 2014
    ....
  32. doi request reprint Risky alcohol use predicts temporal mismatch negativity impairments in young people with bipolar disorder
    Kate M Chitty
    Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Sydney, Australia Electronic address
    Biol Psychol 99:60-8. 2014
    ..Given the increasing use of glutamatergic agents for BD treatment, this finding is important clinically. ..
  33. pmc Cognitive impairment with and without depression history: an analysis of white matter microstructure
    Shantel L Duffy
    Ageing Brain Centre, Brain and Mind Research Institute, University of Sydney, Camperdown, Australia, and the Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, Australia
    J Psychiatry Neurosci 39:135-43. 2014
    ..The present study examined white matter microstructure in patients with MCI with and without a history of major depression compared with healthy controls...
  34. ncbi request reprint When euthymia is just not good enough: the neuropsychology of bipolar disorder
    Amanda Olley
    School of Psychiatry, University of New South Wales and Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Sydney, Australia
    J Nerv Ment Dis 193:323-30. 2005
    ....
  35. ncbi request reprint Transient loss of motor-evoked responses associated with caudal injection of morphine in a patient with spondylolisthesis undergoing spinal fusion
    Peter R J Gibson
    Children s Hospital at Westmead, Westmead, Australia
    Paediatr Anaesth 16:568-72. 2006
    ..The possible mechanisms for this are discussed. We believe that significant L5/S1 spondylolisthesis should be considered a contraindication to the use of caudal epidural injections...
  36. doi request reprint Transcranial motor-evoked potentials combined with response recording through compound muscle action potential as the sole modality of spinal cord monitoring in spinal deformity surgery
    Brian Hsu
    Department of Orthopaedics, The Children s Hospital at Westmead, University of Sydney, Australia
    Spine (Phila Pa 1976) 33:1100-6. 2008
    ..This study is a prospective review of all spinal cord monitoring procedures in our unit from 1999 to 2004 in patients undergoing spinal deformity correction surgery...
  37. doi request reprint A meta-analysis of neuropsychological functioning in first-episode bipolar disorders
    Rico S C Lee
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia Department of Psychology, Macquarie University, Sydney, Australia Electronic address
    J Psychiatr Res 57:1-11. 2014
    ..Future studies need to more clearly characterise the presence of psychotic features, and the nature and number of previous mood episodes. ..
  38. doi request reprint Investigating the role of glutathione in mismatch negativity: An insight into NMDA receptor disturbances in bipolar disorder
    Kate M Chitty
    Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Sydney, Australia Electronic address
    Clin Neurophysiol 126:1178-84. 2015
    ....
  39. doi request reprint A longitudinal proton magnetic resonance spectroscopy study investigating oxidative stress as a result of alcohol and tobacco use in youth with bipolar disorder
    Kate M Chitty
    Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Sydney, Australia Electronic address
    J Affect Disord 175:481-7. 2015
    ....
  40. doi request reprint A systematic review and meta-analysis of eye-tracking studies in children with autism spectrum disorders
    Eleni A Papagiannopoulou
    a Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, Australia
    Soc Neurosci 9:610-32. 2014
    ..The heterogeneity associated with the mouth fixation data precludes any definitive statement as to the robustness of these findings. ..
  41. doi request reprint The impact of alcohol and tobacco use on in vivo glutathione in youth with bipolar disorder: an exploratory study
    Kate M Chitty
    Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Sydney, Australia Electronic address
    J Psychiatr Res 55:59-67. 2014
    ....
  42. doi request reprint Stress-induced grey matter loss determined by MRI is primarily due to loss of dendrites and their synapses
    Mustafa S Kassem
    The Brain and Mind Research Institute, University of Sydney, 100 Mallett Street, Camperdown, NSW 2050, Australia
    Mol Neurobiol 47:645-61. 2013
    ..This quantitative study is the first to relate GMV changes in the cortex measured with MRI to volume changes in cellular constituents of the grey matter...
  43. doi request reprint Pathways to alcohol-induced brain impairment in young people: a review
    Daniel F Hermens
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Cortex 49:3-17. 2013
    ....
  44. doi request reprint Alcohol use and mismatch negativity in young patients with psychotic disorder
    Kate M Chitty
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    Neuroreport 22:918-22. 2011
    ..This may reflect an additive effect of N-methyl-D-aspartate receptor hypofunction and high-alcohol consumption...
  45. ncbi request reprint Cognitive compromise in bipolar disorder with chronic cannabis use: cause or consequence?
    Catherine M Cahill
    University of New South Wales, School of Psychiatry, Sydney, Australia
    Expert Rev Neurother 6:591-8. 2006
    ..The findings are contextualized within bipolar disorder, examining functional outcome...
  46. ncbi request reprint A fiber-optic system for recording skin conductance in the MRI scanner
    Jim Lagopoulos
    University of New South Wales, Sydney, Australia
    Behav Res Methods 37:657-64. 2005
    ..5 and 3.0 Tesla MRI scanners running EPI sequences. This system was able to safely record SCRs free of RF interference during an fMRI experiment, and the fiber-optic design of the transducer eliminated any artifacts on the MRI scan...
  47. ncbi request reprint Functional brain maps of Tower of London performance: a positron emission tomography and functional magnetic resonance imaging study
    Ulrich Schall
    Centre for Mental Health Studies, University of Newcastle, New South Wales, Australia
    Neuroimage 20:1154-61. 2003
    ..These results imply consistency across the two neuroimaging modalities, particularly for the assessment of prefrontal brain function when using a parametric TOL adaptation...
  48. ncbi request reprint Functional MRI BOLD response to Tower of London performance of first-episode schizophrenia patients using cortical pattern matching
    Paul E Rasser
    Neuroscience Institute of Schizophrenia and Allied Disorders NISAD, Australia
    Neuroimage 26:941-51. 2005
    ....
  49. doi request reprint Anatomical abnormalities of the anterior cingulate and paracingulate cortex in patients with bipolar I disorder
    Alex Fornito
    Melbourne Neuropsychiatry Centre, The University of Melbourne, Melbourne, Australia
    Psychiatry Res 162:123-32. 2008
    ..These findings suggest that bipolar disorder is associated with more pronounced changes in the PaC, and that reliance on volumetric measures alone may obscure more subtle differences...
  50. ncbi request reprint A matter of motion or an emotional matter? Management of depression in Parkinson's disease
    Jim Lagopoulos
    School of Psychiatry, The University of New South Wales, Australia
    Expert Rev Neurother 5:803-10. 2005
    ..The focus of this review is to provide an overview of current knowledge regarding depression in Parkinson's disease, followed by a practical discussion addressing the issues of the detection, diagnosis and treatment...
  51. ncbi request reprint Diffuse axonal injury in severe traumatic brain injury visualized using high-resolution diffusion tensor imaging
    Jian Xu
    Department of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway
    J Neurotrauma 24:753-65. 2007
    ..In conclusion, DTI holds great promise as a diagnostic tool to identify and quantify the degree of white matter injury in TBI patients...