Matthew W Kemp

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. doi request reprint Obesity and the developmental origins of health and disease
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Subiaco, Western Australia, Australia
    J Paediatr Child Health 48:86-90. 2012
  2. doi request reprint Preterm birth, infection, and inflammation advances from the study of animal models
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 17:619-28. 2010
  3. pmc Exposure to in utero lipopolysaccharide induces inflammation in the fetal ovine skin
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 18:88-98. 2011
  4. pmc Inflammation of the fetal ovine skin following in utero exposure to Ureaplasma parvum
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 18:1128-37. 2011
  5. doi request reprint Intra-amniotic administration of E coli lipopolysaccharides causes sustained inflammation of the fetal skin in sheep
    Li Zhang
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 19:1181-9. 2012
  6. pmc Selective exposure of the fetal lung and skin/amnion (but not gastro-intestinal tract) to LPS elicits acute systemic inflammation in fetal sheep
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    PLoS ONE 8:e63355. 2013
  7. doi request reprint Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep
    Jeffrey A Keelan
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Am J Obstet Gynecol 204:546.e10-7. 2011
  8. doi request reprint Maternal administration of solithromycin, a new, potent, broad-spectrum fluoroketolide antibiotic, achieves fetal and intra-amniotic antimicrobial protection in a pregnant sheep model
    Jeffrey A Keelan
    School of Women s and Infants Health, The University of Western Australia, Perth, Western Australia, Australia
    Antimicrob Agents Chemother 58:447-54. 2014

Collaborators

Detail Information

Publications8

  1. doi request reprint Obesity and the developmental origins of health and disease
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Subiaco, Western Australia, Australia
    J Paediatr Child Health 48:86-90. 2012
    ..Here, we review the evolution of 'the developmental origins of health and disease' as a concept and discuss recent advances in the association of specific stimuli to obesity, an epidemic cause of human morbidity and mortality...
  2. doi request reprint Preterm birth, infection, and inflammation advances from the study of animal models
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 17:619-28. 2010
    ..Herein, we review important developments in our understanding of the link between preterm birth and fetal inflammation subsequent to infection, gained from studies undertaken in animal models...
  3. pmc Exposure to in utero lipopolysaccharide induces inflammation in the fetal ovine skin
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 18:88-98. 2011
    ..These novel data strongly suggests that the fetal skin acts as an important mediator of the fetal inflammatory response and as such may contribute to preterm birth...
  4. pmc Inflammation of the fetal ovine skin following in utero exposure to Ureaplasma parvum
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 18:1128-37. 2011
    ..These novel findings provide further support for the role of the fetal skin in the development of fetal inflammation and the preterm birth that may follow...
  5. doi request reprint Intra-amniotic administration of E coli lipopolysaccharides causes sustained inflammation of the fetal skin in sheep
    Li Zhang
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 19:1181-9. 2012
    ..These novel data suggest that the fetal skin may cause prolonged in utero inflammatory response causally associated with preterm birth...
  6. pmc Selective exposure of the fetal lung and skin/amnion (but not gastro-intestinal tract) to LPS elicits acute systemic inflammation in fetal sheep
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    PLoS ONE 8:e63355. 2013
    ..These novel findings reveal differential fetal organ responses to pro-inflammatory stimulation and shed light on the pathogenesis of fetal systemic inflammation after exposure to chorioamnionitis...
  7. doi request reprint Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep
    Jeffrey A Keelan
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Am J Obstet Gynecol 204:546.e10-7. 2011
    ..The objective of the study was to explore the maternal-fetal pharmacokinetics of intraamniotic (IA), intravenous (IV), or intramuscular (IM) administration of erythromycin or azithromycin in a pregnant sheep model...
  8. doi request reprint Maternal administration of solithromycin, a new, potent, broad-spectrum fluoroketolide antibiotic, achieves fetal and intra-amniotic antimicrobial protection in a pregnant sheep model
    Jeffrey A Keelan
    School of Women s and Infants Health, The University of Western Australia, Perth, Western Australia, Australia
    Antimicrob Agents Chemother 58:447-54. 2014
    ..Our findings suggest that CEM-101 may provide, for the first time, an effective antimicrobial approach for the prevention and treatment of intrauterine infection and early prevention of preterm birth. ..