Matthew W Kemp

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. doi request reprint Obesity and the developmental origins of health and disease
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Subiaco, Western Australia, Australia
    J Paediatr Child Health 48:86-90. 2012
  2. doi request reprint Preterm birth, infection, and inflammation advances from the study of animal models
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 17:619-28. 2010
  3. pmc Exposure to in utero lipopolysaccharide induces inflammation in the fetal ovine skin
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 18:88-98. 2011
  4. pmc Inflammation of the fetal ovine skin following in utero exposure to Ureaplasma parvum
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 18:1128-37. 2011
  5. pmc Intra-amniotic administration of E coli lipopolysaccharides causes sustained inflammation of the fetal skin in sheep
    Li Zhang
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 19:1181-9. 2012
  6. pmc Selective exposure of the fetal lung and skin/amnion (but not gastro-intestinal tract) to LPS elicits acute systemic inflammation in fetal sheep
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    PLoS ONE 8:e63355. 2013
  7. ncbi request reprint Intrauterine Candida albicans infection elicits severe inflammation in fetal sheep
    Matthew S Payne
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Pediatr Res 75:716-22. 2014
  8. doi request reprint Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep
    Jeffrey A Keelan
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Am J Obstet Gynecol 204:546.e10-7. 2011
  9. ncbi request reprint Polymyxin B agonist capture therapy for intrauterine inflammation: proof-of-principle in a fetal ovine model
    Masatoshi Saito
    1School of Women s and Infants Health, The University of Western Australia, Perth, Western Australia
    Reprod Sci 21:623-31. 2014
  10. pmc High-Resolution Melt PCR Analysis for Genotyping of Ureaplasma parvum Isolates Directly from Clinical Samples
    Matthew S Payne
    School of Women s and Infants Health, University of Western Australia, Subiaco, WA, Australia
    J Clin Microbiol 52:599-606. 2014

Collaborators

Detail Information

Publications14

  1. doi request reprint Obesity and the developmental origins of health and disease
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Subiaco, Western Australia, Australia
    J Paediatr Child Health 48:86-90. 2012
    ..Here, we review the evolution of 'the developmental origins of health and disease' as a concept and discuss recent advances in the association of specific stimuli to obesity, an epidemic cause of human morbidity and mortality...
  2. doi request reprint Preterm birth, infection, and inflammation advances from the study of animal models
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 17:619-28. 2010
    ..Herein, we review important developments in our understanding of the link between preterm birth and fetal inflammation subsequent to infection, gained from studies undertaken in animal models...
  3. pmc Exposure to in utero lipopolysaccharide induces inflammation in the fetal ovine skin
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 18:88-98. 2011
    ..These novel data strongly suggests that the fetal skin acts as an important mediator of the fetal inflammatory response and as such may contribute to preterm birth...
  4. pmc Inflammation of the fetal ovine skin following in utero exposure to Ureaplasma parvum
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 18:1128-37. 2011
    ..These novel findings provide further support for the role of the fetal skin in the development of fetal inflammation and the preterm birth that may follow...
  5. pmc Intra-amniotic administration of E coli lipopolysaccharides causes sustained inflammation of the fetal skin in sheep
    Li Zhang
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Reprod Sci 19:1181-9. 2012
    ..These novel data suggest that the fetal skin may cause prolonged in utero inflammatory response causally associated with preterm birth...
  6. pmc Selective exposure of the fetal lung and skin/amnion (but not gastro-intestinal tract) to LPS elicits acute systemic inflammation in fetal sheep
    Matthew W Kemp
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    PLoS ONE 8:e63355. 2013
    ..These novel findings reveal differential fetal organ responses to pro-inflammatory stimulation and shed light on the pathogenesis of fetal systemic inflammation after exposure to chorioamnionitis...
  7. ncbi request reprint Intrauterine Candida albicans infection elicits severe inflammation in fetal sheep
    Matthew S Payne
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Pediatr Res 75:716-22. 2014
    ..in preterm birth and fetal injury, as a result of their colonization of either the vagina and/or the amniotic cavity. We hypothesized that intraamniotic Candida albicans would cause a vigorous, acute fetal inflammatory response...
  8. doi request reprint Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep
    Jeffrey A Keelan
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Am J Obstet Gynecol 204:546.e10-7. 2011
    ..The objective of the study was to explore the maternal-fetal pharmacokinetics of intraamniotic (IA), intravenous (IV), or intramuscular (IM) administration of erythromycin or azithromycin in a pregnant sheep model...
  9. ncbi request reprint Polymyxin B agonist capture therapy for intrauterine inflammation: proof-of-principle in a fetal ovine model
    Masatoshi Saito
    1School of Women s and Infants Health, The University of Western Australia, Perth, Western Australia
    Reprod Sci 21:623-31. 2014
    ..They suggest the potential for agonist capture as a conceptual means of resolving the proparturition inflammation caused by infection of the amniotic cavity. ..
  10. pmc High-Resolution Melt PCR Analysis for Genotyping of Ureaplasma parvum Isolates Directly from Clinical Samples
    Matthew S Payne
    School of Women s and Infants Health, University of Western Australia, Subiaco, WA, Australia
    J Clin Microbiol 52:599-606. 2014
    ..Choice of reaction reagents was found to be crucial to allow sufficient sensitivity to differentiate U. parvum serovars directly from clinical swabs rather than requiring cell enrichment using microbial culture techniques. ..
  11. doi request reprint Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes
    Lisa F Stinson
    School of Women s and Infants Health, King Edward Memorial Hospital, The University of Western Australia, 374 Bagot Road, Subiaco, Perth, Western Australia 6008, Australia
    Reproduction 147:313-20. 2014
    ..These results support the further investigation of intra-amniotically delivered CSAIDs for the prevention of inflammation-mediated PTB...
  12. doi request reprint High-Resolution Melt PCR Analysis for Genotyping of Ureaplasma parvum Isolates Directly from Clinical Samples
    Matthew S Payne
    School of Women s and Infants Health, University of Western Australia, Subiaco, WA, Australia
    J Clin Microbiol 52:599-606. 2014
    ..Choice of reaction reagents was found to be crucial to allow sufficient sensitivity to differentiate U. parvum serovars directly from clinical swabs rather than requiring cell enrichment using microbial culture techniques. ..
  13. pmc Maternal administration of solithromycin, a new, potent, broad-spectrum fluoroketolide antibiotic, achieves fetal and intra-amniotic antimicrobial protection in a pregnant sheep model
    Jeffrey A Keelan
    School of Women s and Infants Health, The University of Western Australia, Perth, Western Australia, Australia
    Antimicrob Agents Chemother 58:447-54. 2014
    ..Our findings suggest that CEM-101 may provide, for the first time, an effective antimicrobial approach for the prevention and treatment of intrauterine infection and early prevention of preterm birth. ..
  14. ncbi request reprint Thermal and mechanical nociceptive threshold testing in pregnant sheep
    Gabrielle C Musk
    School of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, Australia Animal Care and Veterinary Services, University of Western Australia, Crawley, Western Australia, Australia
    Vet Anaesth Analg 41:305-11. 2014
    ..Analgesic regimes were compared in pregnant ewes after laparotomy by measuring thermal (TT) and mechanical (MT) nociceptive thresholds...